Clinical trials: Nervous System Disorders
Transcutaneous Electrical Nerve Stimulation, Blunt Pressure Pain
The Antalgic Effect of Pulse Frequency and Pad Size of TENS on Blunt Pressure Pain
The purpose of this study is to determine the antalgic of surface electrical stimulation with pulse frequencies and pad sizes on blunting pressure pain on healthy human due to various temporal and spatial summations of the…
- Conditions
- Transcutaneous Electrical Nerve Stimulation, Blunt Pressure Pain, Pad Size, Pulse Frequency
- Trial name
- TENS (NCT01999595)
- Testing
- Control TENS, High frequency TENS with large pads, Low frequency TENS with large pads
- Where
- Taiwan
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Chang Gung University
Brain Tumor
Real-time Assessment of Frameless Intrafraction Motion
The purpose of this study is to assess the ability of a modified thermoplastic mask system in keeping an individual head stationary for a predefined amount of time.
- Trial name
- NCT01202539
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Muscle Weakness, Sports Performance
Light Therapy and Electrical Stimulation on Functional Performance in Volleyball Athletes
Background: Volleyball players constantly perform vertical jumps, the higher the height of the jump is better sports performance of these players. Several methods have been tested to improve jumping performance in these players.
- Trial name
- NCT02443701
- Testing
- Exercise, LASER, NMES
- Where
- Brazil
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Centro de Traumatologia do Esporte
Sleep Deprivation, Sleep Hygiene
Vitoria Sleep Smart City: Interactive Intervention for Sleep Improvement
Currently, the investigators know that there is a high and increasing prevalence of sleep quality and quantity deficits in the general population with the social and health consequences that this entails.
- Trial name
- SMARTCITY (NCT05066581)
- Testing
- Live Chat
- Where
- Spain
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Araba
Movement Disorders (Incl Parkinsonism), Tremor Familial Essential, 1
MRI Study of Brain Activity in Healthy Adults and Individuals With Parkinsonism and Rapid Eye Movement Disorder.
This proposal is focused on developing a reliable, valid, and reproducible imaging techniques and statistical methodology for segregation of various forms of Parkinsonism from healthy adults without Parkinsonism.
- Conditions
- Movement Disorders (Incl Parkinsonism), Tremor Familial Essential, 1, REM Sleep Behavior Disorder
- Trial name
- NCT01547481
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Stroke
Neuro-rehabilitation Training Effects on Motion and Quality of Life After Acute Stroke and Post Stroke
High intensity motion improves motor functions and quality of life in a neurologist. The investigators want to improve the clinical condition and quality of life of post-STROKE participants with a special sensory motor and visual…
- Trial name
- NCT03736200
- Testing
- Exergaming group, Physiotherapy, Exergaming group 2/day
- Where
- Hungary
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Somogy Megyei Kaposi Mór Teaching Hospital
Tinnitus
Nitrous Oxide Treatment for Tinnitus
Tinnitus is perception of sound without the presence of an external acoustic stimulus. Approximately 50 million Americans experience chronic tinnitus and of these, 10 million have bothersome tinnitus.
- Trial name
- NCT03365011
- Testing
- Nitrous oxide gas for inhalation
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Depression
Prevention of Depression in Spouses of People With Cognitive Impairment
This study evaluates the effectiveness of a problem-solving training program in preventing depression in the spouses or family caregivers of persons with mild cognitive impairment or early dementia.
- Trial name
- NCT00321971
- Testing
- PST-MCI/AD Caregiving, NT-MCI/AD Caregiving
- Where
- 2 sites in United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Deafness, Bilateral
Study of the Role of Top-down Processes in Neuronal Reorganization and Recovery From Sensory Loss: an Exploratory Behavioral and Electroencephalographic Study in Cochlear-supported Deaf Patients
This study posits that central top-down processes (attention, inhibition), marked by alpha oscillations in EEG, play a key role.
- Trial name
- REASCENT (NCT07500909)
- Testing
- neurophysiological assessment, Cognitive, behavioral and quality of life assessment
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Obstructive Sleep Apnea, Atrial Fibrillation
Effective Conversion of Individuals at Risk
This study aims to guide participants in recognizing their OSA (obstructive sleep apnea) and AFib (atrial fibrillation) symptoms, realizing what medical conditions can cause these symptoms (if any) and inform the participants on…
- Trial name
- NCT05112757
- Testing
- Smartphone application use
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Philips Clinical & Medical Affairs Global
Myalgic Encephalomyelitis, Chronic Fatigue Syndrome
Cardiovascular Analysis of PEM
The purpose of this study is to examine cardiopulmonary function in Chronic Fatigue Syndrome (CFS) patients and determine how it relates to the common symptom of Post-exertional malaise (PEM).
- Trial name
- NCT04740736
- Testing
- Saline Infusion
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Mild Cognitive Impairment, Alzheimer's Disease
Aftobetin-HCl and Fluorescence Detection Measured by Sapphire II to Determine the Number and Timing of Administrations
This is an open-label study to evaluate Aftobetin-HCl and florescence detection as measured by the Sapphire II device. Performance of Part I of the study has been completed (15 subjects received a single administration of…
- Trial name
- NCT02928211
- Testing
- Sapphire II, Aftobetin-HCl, Positron Emission Tomography
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Cognoptix, Inc.
Memory Disorders, Anxiety Depression
Coriandrum Sativum Seeds Improve Memory, Alleviate Anxiety and Depression, and Enhance Sleep Quality in University Students: A Randomized Controlled Trial
C. sativum could potentially serve as a memory enhancer for university students. It is considered a preferable option to stimulant drugs due to its safety profile. Additionally, C.
- Conditions
- Memory Disorders, Anxiety Depression, Sleep
- Trial name
- NCT05999071
- Testing
- Coriandrum sativum seeds
- Where
- Jordan
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- The Hashemite University
Aging, Aphasia
Exercise Effects on Word Learning
The aging Veteran population will substantially increase over the next 10 years, as the 24.9% of Veterans who are currently between 55-64 years of age join the 38.5% who are already over age 65.
- Trial name
- NCT03370471
- Testing
- Retrieval Practice + Moderate Intensity Exercise, Retrieval Practice + Gentle Stretching, Study Only + Moderate Intensity Exercise
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Dizziness, Neck Pain
Dynamic Neck Function During Gait in Patients With Dizziness
This study aims to explore the possible association between dizziness and head-on trunk-movements and thus, neck movement and if this differs to healthy controls.
- Conditions
- Dizziness, Neck Pain, Gait
- Trial name
- NCT04626544
- Testing
- Body-worn inertial sensors
- Where
- Norway
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Hearing Impairment, Deafness
RoboHear™ Device: Advanced Haptic Technology That Allows the Deaf to Understand Speech
Pilot study to test the feasibility of translating the English language into haptics (touch sensations)
- Trial name
- NCT03966144
- Testing
- RoboHear Device
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Arkansas
Vertigo, Diseases, Vestibular
Effect of Caffeine Intake in Vestibular Function
Objective: Assess the effect of caffeine in the following vestibular function tests: Cervical Vestibular Evoked Potential (cVEMP), Ocular Vestibular Evoked Potential(oVEMP) and Caloric Test.
- Conditions
- Vertigo, Diseases, Vestibular, Caffeine
- Trial name
- NCT02825199
- Testing
- Caffeine, Non caffeine
- Where
- Brazil
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Instituto Brasiliense de Otorrinolaringologia
Hyperalgesia, Pain Perception
Session-Order Sensitivity of TS and OA in a Capsaicin Crossover Model
Temporal summation (TS) and offset analgesia (OA) are widely used psychophysical endpoints in pain research that index different components of central nociceptive processing.
- Conditions
- Hyperalgesia, Pain Perception, Central Nervous System Sensitization, Pain Threshold
- Trial name
- TS-OA-Cap (NCT07625475)
- Testing
- Topical 0.075% capsaicin cream (Zostrix), Topical vehicle lotion (Lubriderm)
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Guelph
Cerebral Palsy, Spastic
Investigation of Motor Imaging Skills in Children With Spastic Cerebral Palsy
The aim of this study was to investigate implicit and explicit motor imagery skills in children with spastic cerebral palsy and typically developing children.
- Trial name
- NCT06343701
- Testing
- Implicit motor imagery, Explicit motor imagery
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Stroke, Healthy
Effects of Vibration on Motor Function of Survivors of Chronic Stroke
The aim of this study is to evaluate how vibration of the tendons enhances arm and hand training in survivors of chronic stroke.
- Trial name
- NCT06663501
- Testing
- Assisted Motion with Enhanced Sensation training
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
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