Clinical trials: Nervous System Disorders
Chronic Subdural Hematoma, Recurrence
The Effectiveness and Safety of Body Posture in Preventing Postoperative Recurrence for Chronic Subdural Hematoma
This study aims to investigate the effectiveness and safety of body posture to improve intracranial pressure in preventing postoperative recurrence for chronic subdural hematoma
- Trial name
- NCT06401772
- Testing
- Intracranial Hypotension Targeted(IHT) Body Posture
- Where
- China
- Volunteers
- 830 people
- Sponsor
- Huashan Hospital
Spinal Cord Injuries
Turkish Version of the Neurogenic Bladder Symptom Score Questionnaire: a Cross-cultural Adaptation, Reliability and Validity Study
Turkish version of the Neurogenic Bladder Symptom Score questionnaire: a cross-cultural adaptation, reliability and validity study
- Trial name
- NCT03964077
- Testing
- Neurogenic Bladder Symptom Score Questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Fibromyalgia, Nociplastic Pain
Vestibular Innovation in Pain 2
Fibromyalgia is the most common centralized pain disorder, affecting up to 3% of the population. Current treatments are incompletely effective, often poorly tolerated, and costly: there remains an urgent need for novel…
- Trial name
- VIPR (NCT07423377)
- Testing
- Vestibulocortical Stimulation
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Parkinsonian Syndrome
Study of Individuals With Parkinson's Symptoms But in Whom There is Diagnostic Uncertainty
The overall goal of this study is to evaluate the use of dopamine transporter (DAT) imaging as a diagnostic tool in subjects with early parkinsonian symptoms, in whom Parkinson's disease (PD) or parkinsonian syndrome (PS) is…
- Trial name
- NCT00129675
- Testing
- [123I]ß CIT
- Where
- United States
- Volunteers
- 169 people
- Sponsor
- Institute for Neurodegenerative Disorders
Parkinson Disease, Acupuncture
Acupuncture for Management of Balance Impairment in Patients With Parkinson's Disease
This plan is to evaluate the effectiveness of scalp acupuncture, a modern acupuncture technique specialized to neurological disorders, in managing motor function and body balance for PD patients.
- Trial name
- NCT03178175
- Testing
- Acupuncture, Needle Insertion
- Where
- Taiwan
- Volunteers
- 4 people
- Sponsor
- Chang Bing Show Chwan Memorial Hospital
Parkinson Disease, Dyskinesia, Medication-Induced
Efficacy, Safety and Pharmacokinetic Study of CPL500036 in Patients with Levodopa Induced Dyskinesia
The aim of the study is to determine potential anti-dyskinetic properties of CPL500036 (PDE10A inhibitor) in Parkinson disease patients suffering from levodopa Induced dyskinesia.
- Trial name
- NCT05297201
- Testing
- CPL500036 - low dose, CPL500036 - high dose
- Where
- 16 sites in Poland, Ukraine
- Volunteers
- 105 people
- Sponsor
- Celon Pharma SA
Dystonia, Focal
Motor and Non-motor Symptoms in Cervical Dystonia
In this monocenter, observational, non-interventional, prospective, open label study investigators will enrol 43 CD patients from the outpatient Movement Disorders Clinic of the Department of Human Neurosciences, Sapienza…
- Trial name
- Royal (NCT04560101)
- Testing
- botulinum toxin A
- Where
- Italy
- Volunteers
- 43 people
- Sponsor
- University of Roma La Sapienza
Granulomatosis With Polyangiitis (GPA), Microscopic Polyangiitis (MPA)
Study of IFX-1 to Replace Steroids in Patients With Granulomatosis With Polyangiitis and Microscopic Polyangiitis.
The purpose of the study is to evaluate the efficacy of IFX-1 treatment as replacement for glucocorticoid (GC) therapy in subjects with polyangiitis (GPA) or microscopic polyangiitis (MPA).
- Trial name
- IXchange (NCT03895801)
- Testing
- IFX-1, Glucocorticoid (GC)
- Where
- 76 sites in Belgium, Czechia and 9 more
- Volunteers
- 57 people
- Sponsor
- InflaRx GmbH
Neurocysticercosis, Tropical Disease
Parenchymal and Extraparenchymal Neurocysticercosis-A Registry Based Study
Neurocysticercosis(NCC) is the commonest parasitic infection of the central nervous system. It is the commonest cause of focal seizures in India.
- Conditions
- Neurocysticercosis, Tropical Disease, Tenia Solium Infection
- Trial name
- NCT04706819
- Volunteers
- 1,000 people
- Sponsor
- All India Institute of Medical Sciences
Depression, Involutional
Function of Catecholamines in the Brain During Depression
This study will explore brain function related to depressive symptoms and will examine DNA for genes that may be involved in depressive disorders, particularly genes that regulate synthesis and metabolism of the brain…
- Trial name
- NCT00082030
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Intracerebral Hemorrhage (ICH)
GLP-1 CellBeads® for the Treatment of Stroke Patients With Space-occupying Intracerebral Hemorrhage
The objective of this study is to assess the safety of GLP-1 CellBeads® in patients with space-occupying intracerebral hemorrhage.
- Trial name
- NCT01298830
- Testing
- GLP-1 CellBeads
- Where
- 6 sites in Germany
- Volunteers
- 11 people
- Sponsor
- CellMed AG, a subsidiary of BTG plc.
Labor Pain
A Novel Approach to Optimize Programmed Intermittent Epidural Bolus (PIEB) Delivery for Labour Analgesia
Programmed intermittent epidural bolus (PIEB) for labour analgesia allows an epidural pump to be programmed to deliver small amounts of the local anesthetic and opioid solution at regularly timed intervals.
- Trial name
- NCT03871530
- Testing
- Coordinate A, Coordinate B, Coordinate C
- Where
- Canada
- Volunteers
- 55 people
- Sponsor
- IWK Health Centre
Ischemic Stroke
Effects of Mepivacaine on the Neurological Sequelae of Cerebral Infarction
A patient, suffering from cortical blindness after a bi-occipital infarction 1 year earlier, regained near-normal vision in the right visual hemifield a few minutes after subcutaneous administration of mepivacaine.
- Trial name
- MEPI-AVC (NCT05222828)
- Testing
- Carbocaine Injectable Product
- Where
- France
- Volunteers
- 38 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Wilsons Disease
sCD163 and sMR in Wilsons Disease - Associations With Disease Severity and Fibrosis
The aim is to investigate macrophage activation markers and correlations to liver fibrosis in patients with Wilsons Disease. Researchers wish to investigate associations to neurologic and metabolic liver function.
- Trial name
- NCT02702765
- Testing
- Fibroscan, Ultrasound, Galactose
- Where
- Denmark
- Volunteers
- 33 people
- Sponsor
- University of Aarhus
Obstructive Sleep Apnea Syndrome
Home Nasal Pressure for Sleep Apnea Management in Primary Case
Primary objectives: To determine the efficacy and cost-effectiveness of a management program for patients with obstructive sleep apnea syndrome (OSAS) carried out in primary or specialist healthcare.
- Trial name
- Primary (NCT02141165)
- Testing
- Diagnosis, autoCPAP, follow up.
- Where
- Spain
- Volunteers
- 280 people
- Sponsor
- Sociedad Española de Neumología y Cirugía Torácica
Multiple Sclerosis
Depression and Fatigue in MS Patients Treated With Betaferon.
This study aims to evaluate the occurence and severity of fatigue and depression in multiple sclerosis patients and the impact of Betaferon treatment on symptoms alterations.
- Trial name
- FADO (NCT01354665)
- Testing
- Interferon beta-1b (Betaferon, BAY86-5046)
- Where
- Poland
- Volunteers
- 567 people
- Sponsor
- Bayer
Cardiovascular Diseases, Carotid Artery Diseases
Vitamin E and C to Slow Progression of Common Carotid Artery Plaque Build-Up
This study will evaluate the effects of vitamin E supplementation in retarding the progression of common carotid artery intima-media thickening in African Americans.
- Conditions
- Cardiovascular Diseases, Carotid Artery Diseases, Intracranial Arteriosclerosis, Cerebrovascular Disorders
- Trial name
- NCT00000600
- Testing
- Vitamin E, Vitamin C
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Temporomandibular Disorders (TMD)
Journaling Intervention for Temporomandibular Disorder (TMD) and Chronic Overlapping Pain
The goal of this clinical trial is to learn whether a 2-week gratitude journaling activity is feasible and acceptable for individuals with Temporomandibular Disorder (TMD) and chronic overlapping pain.
- Trial name
- NCT06977100
- Testing
- Gratitude, General Wellness
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Florida
Nutritional Deficiency, Gastrointestinal Cancers
A Randomized, Double-blind, Placebo-controlled, Prospective, Multi-center Trial Evaluating the Improvement of Nutritional Status and Sarcopenia With Silkworm Pupa Tablets in Patients With Malignancies
This is a randomized, double-blind, placebo-controlled, parallel-group, prospective, multi-center clinical trial, to evaluate the efficacy of silkworm pupa tablets in improving nutritional status and sarcopenia in patients with…
- Conditions
- Nutritional Deficiency, Gastrointestinal Cancers, Sarcopenia
- Trial name
- NCT07554807
- Testing
- Silkworm pupa tablets
- Where
- 4 sites in China
- Volunteers
- 480 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Dementia, Sundowning
Aromatherapy Formulas for Sundowning and Sleep Quality in Patients With Dementia.
Dementia is common in aging societies and is often accompanied by sundowning syndrome and sleep problems. These symptoms can be very distressing for patients and place a heavy burden on family members and professional caregivers.
- Trial name
- AROMA-SUN (NCT07288736)
- Testing
- Aromatherapy Formula A, Aromatherapy Formula B
- Where
- 2 sites in Taiwan
- Volunteers
- 35 people
- Sponsor
- National Cheng-Kung University Hospital
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