Clinical trials: Nervous Vagus
Vagus Nerve Autonomic Disorder
Comparison Of The Immediate Effects Of Manipulation On The Autonomic Nervous System
High velocity low amplitude thrust applied at the vertebral level during spinal manipulation is thought to slide the vertebrae over each other and alter segmental biomechanics.
- Trial name
- NCT05850910
- Testing
- Supine practice group, Prone application group
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Methylene Blue, Recurrent Laryngeal Nerve Injuries
Methylene Blue Spray for Identification of Recurrent Laryngeal Nerve and Parathyroid Gland
Thyroidectomy is the procedure by which surgeons treat various thyroid diseases and is considered the commonest endocrinal surgery. Yet, it carries a risk for intraoperative complications.
- Conditions
- Methylene Blue, Recurrent Laryngeal Nerve Injuries, Parathyroid Gland
- Trial name
- NCT05113628
- Testing
- methylene blue identification
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Zagazig University
Chronic Tension-Type Headache, Episodic Tension-Type Headache
Treatment of Tension Headache Using Soft Tissue Techniques VS Vagus Stimulation Techniques.
A treatment based on manual therapy and vagus nerve stimulation is more effective than manual therapy only to reduce frequency, intensity and pressure pain threshold in patients with tension type headache.
- Trial name
- NCT05097300
- Testing
- Suboccipital inhibition, Ischemic pressure, Passive stretching
- Where
- 2 sites in Spain
- Volunteers
- 42 people
- Sponsor
- Lucia Trullenque Espallargas
Efficacy, Self, Fatigue; Muscle, Heart
Neuromodulation of the Autonomic Nervous System in Athletes
There are few studies in the literature that have evaluated the effects of using percutaneous stimulation of the auricular branch of the vagus nerve for sports purposes (to accelerate recovery after physical exertion).
- Conditions
- Efficacy, Self, Fatigue; Muscle, Heart, Fatigue, Mental, Fatigue; Combat
- Trial name
- NANSA (NCT06281795)
- Testing
- tVNS
- Where
- Russia
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Bakulev Scientific Center of Cardiovascular Surgery
Spinal Cord Injuries, Spinal Cord Diseases
Transcutaneous Auricular Vagus Nerve Stimulation in Spinal Cord Injury
This study is a single blinded prospective randomized monocentric study examining the effectiveness of transcutaneous auricular vagus nerve stimulation paired with rehabilitation and low frequency/antidromic stimulation of the…
- Conditions
- Spinal Cord Injuries, Spinal Cord Diseases, Nervous System Diseases, Trauma, Nervous System
- Trial name
- taVNS (NCT05852379)
- Testing
- active taVNS
- Volunteers
- 10 people
- Sponsor
- Possover International Medical Center AG
Insomnia
A Study of Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) for Insomnia During Pregnancy
The goal of this clinical trial is to learn whether transcutaneous auricular vagus nerve stimulation (taVNS) can treat insomnia during pregnancy. It will also learn about the safety of taVNS for pregnant women and their fetuses.
- Trial name
- NCT07730762
- Testing
- transcutaneous auricular vagus nerve stimulation
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Xijing Hospital
Refractory Epilepsy
Effect of Blue Light on Vagus Nerve Stimulation in Patients With Refractory Epilepsy
Vagus nerve stimulation (VNS) is an adjunctive treatment for refractory epilepsy. Although widely used, there is still a substantial number of patients with insufficient response.
- Trial name
- BLUELIGHTVNS (NCT06304389)
- Testing
- electroencephalography, electrocardiogram, pupillometry, evoked potentials, light administration, transcutaneous vagus nerve stimulation, electroencephalography, pupillometry, electrocardiogram, light administration
- Where
- Belgium
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Ischemic Stroke, Post-stroke Dysphagia
EEG Feedback-Based Vagus Nerve Stimulation for Post-Stroke Dysphagia
The goal of this clinical trial is to learn if electroencephalogram (EEG) biofeedback-guided transcutaneous auricular vagus nerve stimulation (taVNS) works to treat swallowing difficulties (dysphagia) in adults after a stroke.
- Conditions
- Ischemic Stroke, Post-stroke Dysphagia, Swallowing Disorders
- Trial name
- NCT07894315
- Testing
- EEG Biofeedback-Guided taVNS, Conventional taVNS
- Where
- 6 sites in China
- Volunteers
- 60 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Auricular Vagus Nerve Stimulation, Transcutaneous
Effects of Vagus Nerve Stimulation on the Autonomic Nervous System
The aim of this study is to determine the effect of vagus nerve stimulation, applied after running exercise, on recovery and fatigue in healthy young adults.
- Conditions
- Auricular Vagus Nerve Stimulation, Transcutaneous, Recovery
- Trial name
- NCT07371676
- Testing
- Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul Gelisim University
Spontaneous Intracerebral Hemorrhage, Motor Function
Rehabilitation Paired with VNS for Motor Function Recovery
The goal of this clinical trial is to investigate the efficacy and safety of vagus nerve stimulation (VNS) combined with rehabilitation in improving upper extremity motor function after spontaneous intracerebral hemorrhage (ICH).
- Conditions
- Spontaneous Intracerebral Hemorrhage, Motor Function, Upper Extremity Injury, Rehabilitation
- Trial name
- NCT06892574
- Testing
- Active-VNS
- Volunteers
- 10 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Vestibular Diseases, Vestibular Vertigo
Investigation of the Efficacy of Non-Invasive Vagus Nerve Stimulation and Physiotherapy in Unilateral Vestibular Hypofunction Patients
The purpose of this study: To investigate the effectiveness of non-invasive vagus nerve stimulation and vestibular rehabilitation applications in patients diagnosed with Unilateral Vestibular Hypofunction (UVH).
- Conditions
- Vestibular Diseases, Vestibular Vertigo, Vertigo
- Trial name
- NCT06332326
- Testing
- non-invasive vagus nerve stimulation, vestibular rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Medipol University
Epilepsy
Transcutaneous Auricular Vagus Nerve Stimulation for Pediatric Epilepsy
The purpose of this study is to determine whether transcutaneous auricular vagus nerve stimulation as a complementary therapy is effective in the treatment of pediatric epilepsy.
- Trial name
- NCT02004340
- Testing
- ear vagus nerve stimulator
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- China Academy of Chinese Medical Sciences
Post-COVID / Long-COVID, ME/CFS
Vagus Nerve Stimulation to the Ear to Improve Symptoms in Post-COVID-19 and ME/CFS
This study is testing whether a gentle electrical stimulation of a nerve in the ear, called the vagus nerve, can help reduce fatigue and improve symptoms in people with Post-COVID Syndrome or Myalgic Encephalomyelitis/Chronic…
- Trial name
- STIMPACT (NCT06968104)
- Testing
- transcutaneous vagus nerve stimulation
- Where
- Luxembourg
- Volunteers
- 48 people
- Sponsor
- University of Luxembourg
Spinal Cord Injury, Chronic
taVNS During Exercise and Recovery in Chronic Spinal Cord Injury
This study investigates the effects of transcutaneous auricular vagus nerve stimulation (taVNS) on autonomic cardiovascular regulation during exercise and recovery in individuals with chronic spinal cord injury (SCI).
- Trial name
- taVNS-HRV-SCI (NCT07524491)
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation
- Where
- Spain
- Volunteers
- 35 people
- Sponsor
- University of the Balearic Islands
Healthy Volunteers
Non-Invasive Transcutaneous Auricular Vagus Nerve Stimulation Applied at Different Durations in Healthy Adults
This randomized, participant-blinded, sham-controlled interventional study aims to compare the acute effects of non-invasive transcutaneous auricular vagus nerve stimulation (taVNS) applied at different durations on autonomic…
- Trial name
- taVNS-DUR (NCT07532005)
- Testing
- Active taVNS
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Sinop University
Mother of a Child With Cerebral Palsy
Effect of Vagus Nerve Stimulation and Breathing Exercise on the Autonomic Nervous System
This project will compare the effects of intraaural vagus nerve stimulation and deep breathing exercises on the autonomic nervous system in mothers of children with cerebral palsy.
- Trial name
- NCT06970769
- Testing
- Vagus nerve stimulation, Deep Breathing Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Atlas University
Paralysis, Unilateral, Vocal Cord
Early Intracordal Hyaluronic Acid Injection During Spontaneous Reinnervation for Unilateral Recurrent Laryngeal Nerve Paralysis
Backgrounds: Unilateral vocal cord paralysis caused from recurrent laryngeal nerve (RLN) injury is not an unusual disease and may deteriorate patients'voice and swallowing outcomes.
- Trial name
- NCT02163772
- Testing
- Intracordal hyaluronate injection
- Where
- Taiwan
- Volunteers
- 29 people
- Sponsor
- Chang Gung Memorial Hospital
Drug Resistant Epilepsy
A First in hUman Study for Resistant Epilepsy With the Vagus Nerve stimulatiOn Device by syneRgia medicAl
This is an open label, single arm, interventional, prospective first in human study, designed to evaluate the safety of the NAO.VNS SYSTEM.
- Trial name
- AURORA (NCT06340802)
- Testing
- VNS Treatment
- Where
- 2 sites in Belgium
- Volunteers
- 5 people
- Sponsor
- Synergia Medical
Parkinson Disease (PD)
Synthetic Vasomotion for Glymphatic Enhancement
The goal of this pilot clinical trial is to learn whether a week-long study combining controlled breathing procedures, intermittent exposure to a low-concentration carbon dioxide gas mixture, and noninvasive vagus nerve…
- Trial name
- NCT07814534
- Testing
- Active noninvasive vagus nerve stimulation, Active intermittent hypercapnia, Guided breathing
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Florida Institute for Human and Machine Cognition
Anxiety, PTSD
Rapid Entrainment and Signal-guided Neuromodulation for Behavioral Health
RESYNC-BH is a research study evaluating a personalized, non-drug brain-and-body treatment approach for adults with ongoing behavioral health symptoms such as depression, anxiety, trauma-related symptoms, sleep problems…
- Conditions
- Anxiety, PTSD, ADHD, Depression Disorders
- Trial name
- RESYNC-BH (NCT07812987)
- Testing
- AIP-Informed Integrative Psychotherapy, Transcutaneous Auricular Vagus Nerve Stimulation, Regulated Breathing and Autonomic Regulation
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Tactical Mind Research Coalition, Inc.