Clinical trials: Nervousness
Agitation, Dementia
An Efficacy, and Safety Study Of BXCL501 For The Treatment Of Agitation Associated With Dementia
A randomized, double-blind, placebo-controlled parallel group 3-arm study assessing efficacy, safety, and tolerability of two doses BXCL501 in male and female geriatric residents (65 years and older) with acute agitation…
- Trial name
- NCT05276830
- Testing
- BXCL501
- Where
- 3 sites in United States
- Volunteers
- 5 people
- Sponsor
- BioXcel Therapeutics Inc
Anorexia Nervosa
The Experience of Affective Touch in Anorexia Nervosa
The aim of the present research will be to verify if the pleasantness of affective touch is comparable between women with AN and healthy women while measuring the level of social anhedonia and the lifespan experience of affective…
- Trial name
- AffTouch_AN (NCT05756530)
- Testing
- Affective touch paradigm
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istituto Auxologico Italiano
Carpal Tunnel Syndrome
Comparison of Ultrasound-guided Corticosteroid Injection Versus Corticosteroid Injection and Hydrodissection for Carpal Tunnel Syndrome
The objective of this study is to investigate the effect of ultrasound guided steroid injection versus ultrasound guided steroid hydrodissection to treat patients with CTS.
- Trial name
- NCT04346030
- Testing
- Triamcinolone Acetonide, lidocaine hydrochloride, normal saline
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Music Therapy
Effect of Music Therapy on Postoperative Health Outcomes
Patients underwent surgical procedure experiences acute postoperative pain, but less than half report adequate postoperative pain relief.
- Trial name
- MToPOHO (NCT04155528)
- Testing
- Music therapy
- Volunteers
- 60 people
- Sponsor
- Cairo University
Stroke, Cerebrovascular Accident
Non-invasive Brain Stimulation and Occupational Therapy To Enhance Stroke Recovery
The purpose of this study is to determine whether a non-painful, non-invasive, brain-stimulation technique called transcranial direct current stimulation (tDCS) combined with traditional physical-occupational therapy (OT) will…
- Conditions
- Stroke, Cerebrovascular Accident, CVA, Acute Stroke
- Trial name
- TDCS+OT (NCT00792428)
- Testing
- Real Transcranial Direct Current Stimulation
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Insomnia, Health Adult Subjects
Does Style Matter: Comparison of Moderate- to Low-intensity Styles of Yoga
The goal of this clinical trial is to learn if yoga works to improve sleep and heart health in adults with and without insomnia disorder.
- Conditions
- Insomnia, Health Adult Subjects, Insomnia Disorder, Heart Health Markers
- Trial name
- NCT07638267
- Testing
- Vinyasa yoga, Gentle yoga, Non-active control
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Caitlin Cheruka
Posterior Reversible Encephalopathy Syndrome
Posterior Reversible Encephalopathy Syndrome in the Critically Ill Patients
Posterior Reversible Encephalopathy Syndrome prospective (PRES) registry. Data collection using a standardized form : demographic data and data related to the PRES, including circumstances of onset, dates and times of onset and…
- Trial name
- NCT03470467
- Testing
- No intervention
- Where
- France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ictal Group
Skeletal Muscle Damage, Muscle Inflammation
Protein Supplementation and Muscle Recovery in Football
Soccer is an intermittent sport including a high number of powerful actions such as accelerations, decelerations, changes of direction, jumps and impacts that incorporate a strong eccentric component and may therefore lead to…
- Conditions
- Skeletal Muscle Damage, Muscle Inflammation, Muscle Recovery, Soccer Performance
- Trial name
- PRO-FOOTBALL (NCT03348267)
- Testing
- Milk protein isolate
- Where
- Greece
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Depression, Anxiety
Prevention of ANxiety and Depression Over Risk Assessment
The general goal is to design, develop and evaluate a personalized, self-guided and trans-diagnostic internet-based intervention to prevent anxiety and depression, based on predictive risk algorithms and decision support systems…
- Conditions
- Depression, Anxiety, Prevention, m-Health
- Trial name
- NCT07185867
- Testing
- Pandora-1 app with high levels of personalization, interaction, monitoring and feedback, Pandora-2 app with low levels of personalization, interaction, monitoring and feedback
- Where
- Spain
- Volunteers
- 2,595 people, healthy volunteers welcome
- Sponsor
- The Mediterranean Institute for the Advance of Biotechnology and Health Research
Stroke, Acute, Cerebrovascular Disorders
The Norwegian Tenecteplase Stroke Trial 2
Background: Alteplase is the only approved acute drug treatment in ischemic stroke and aims at dissolving arterial clots causing cerebral ischemia. The overall benefit of alteplase is substantial.
- Conditions
- Stroke, Acute, Cerebrovascular Disorders, Ischemic Stroke
- Trial name
- NOR-TEST 2 (NCT03854500)
- Testing
- Tenecteplase, Alteplase
- Where
- Norway
- Volunteers
- 201 people
- Sponsor
- Haukeland University Hospital
Sarcopenia, Obesity
Investigating the Link Between Advanced Glycation End Products (AGEs) and Muscle Wasting in Sarcobesity
The study aims to explore whether a high level of AGEs (Advanced Glycation end products) derived from the diet may mediate diet-related muscle loss in Western-type diet, influencing the onset and progression of sarcopenia…
- Trial name
- Westernage (NCT06438900)
- Where
- Italy
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliero Universitaria Maggiore della Carita
Pain Management, Total Hip Arthroplasty
Ultrasound-Guided Quadro-Iliac Plane Block for Pain Management After Total Hip Arthroplasty
This prospective, randomized, double-blind study evaluates the analgesic effectiveness of the ultrasound-guided Quadro-Iliac Plane (QIP) block in patients undergoing primary total hip arthroplasty.
- Trial name
- NCT07410000
- Testing
- Quadro-Iliac Plane (QIP) Block
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Bursa City Hospital
Vascular Cognitive Impairment, Alzheimer Disease
Multimodal Biomarkers for Diagnosis and Prognosis in VCI
We will try to 1. establish the correlation of plasma Aβ40 and Aβ42 level, ApoE genotype, MRI imaging markers in the diagnosis and prognosis of VCI patients 2. understand more on the pathophysiology of VCI.
- Trial name
- VCI (NCT04604600)
- Testing
- amyloid PET
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Erectile Dysfunction, Nocturia, Short Term Insomnia, Obstructive Sleep Apnea
Effects of Nightshift Work and Sleep Disturbances on Erectile Function
We aim to observe the unwanted effects of nightshift work and short term insomnia on erectile function of men aged between 25 to 60 years.
- Trial name
- NCT04707807
- Testing
- IIEF-5
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Disorder of Consciousness
Ketamine to Treat Patients With Post-comatose Disorders of Consciousness
The investigators will run a Randomized Clinical Trial with 30 patients with disorders of consciousness (DoC), with intravenous subanesthetic doses of ketamine. Patients will simultaneously undergo TMS-EEG.
- Trial name
- NCT05343507
- Testing
- Ketalar 50 MG/ML Injectable Solution
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- University of Liege
Cerebrovascular Accident (CVA), Chronic Disease
Upper Limb Task-Oriented Rehabilitation With Robotic Exoskeleton for Hemiparetic Stroke Patients
The aim of this study is to evaluate the effects of an assisted rehabilitation treatment through a robotic exoskeleton device on the functional recovery in a group of patients with hemiparesis from lesion of the first motor…
- Conditions
- Cerebrovascular Accident (CVA), Chronic Disease, Stroke Rehabilitation
- Trial name
- RH-LEXOS (NCT03319992)
- Testing
- Upper Arm Rehabilitation Light Exoskeleton (RH-LEXOS)
- Where
- Italy
- Volunteers
- 26 people
- Sponsor
- Scuola Superiore di Studi Universitari e di Perfezionamento Sant'Anna
Postherpetic Neuralgia ( PHN ), Ultrasound Guided, Block, Ultrasound Guided Injection
Effectiveness of Ultrasonography-Guided Serratus Posterior Superior Intercostal Plane Block in Thoracic Postherpetic Neuralgia: A Retrospective Cohort Study
Postherpetic neuralgia (PHN) is a chronic pain syndrome that can be resistant to treatment, leading to physical and social disability, psychological disturbances, and potentially persisting for years .
- Trial name
- pain (NCT07067892)
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Dementia
Cholinesterase Inhibitor Discontinuation
This study tries to determine if stopping certain medications that are used to treat dementia will cause worsening from the patient and family perspective.
- Trial name
- CID (NCT02248636)
- Testing
- Cholinesterase inhibitor
- Where
- 4 sites in United States
- Volunteers
- 72 people
- Sponsor
- VA Office of Research and Development
Postherpetic Neuralgia
A Crossover Study to Evaluate the Safety, Tolerability and Efficacy of XPF-002 in Subjects With Postherpetic Neuralgia (PHN)
The purpose of this trial is to determine if XPF-002 is safe and effective for the treatment of pain in subjects with Postherpetic Neuralgia
- Trial name
- XEN402 (NCT01195636)
- Testing
- XPF-002
- Where
- 24 sites in United States
- Volunteers
- 70 people
- Sponsor
- Xenon Pharmaceuticals Inc.
Telerehabilitation, Neuropsychology
Teleneuropsychological Intervention in Asymptomatic HIV Seropositive Patients: N&C NeuroChange
Currently 37.9 million people are living with human immunodeficiency virus (HIV) around the world (UNAIDS, 2018). Even with antiretroviral treatment (ART), the virus enters the central nervous system and can affect the following…
- Conditions
- Telerehabilitation, Neuropsychology, HIV Dementia
- Trial name
- NCT05571761
- Testing
- Cognitive stimulation program
- Where
- Mexico
- Sponsor
- Universidad Nacional Autonoma de Mexico
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