Clinical trials: Nervousness
ALS (Amyotrophic Lateral Sclerosis)
Intermediate-size Patient Population Expanded Access Protocol
The purpose of this Expanded Access Program is to provide tazbentetol to ALS patients who are not eligible to enroll in an ALS clinical trial.
- Trial name
- NCT07088159
- Testing
- Tazbentetol
- Where
- 16 sites in United States
- Sponsor
- Spinogenix
Primary Hyperalgesia
Sensory Function After Wound Instillation of Capsaicin
The use of capsaicin as a potential analgesic drug for postoperative pain relies on the ability of capsaicin to induce membrane lysis of c-nerve fibers.
- Trial name
- NCT00583180
- Testing
- Capsaicin
- Where
- Denmark
- Volunteers
- 42 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Spinal Cord Injury
Implantable Wireless Brain-Machine Interface System for Spinal Cord Injury: Efficacy and Safety Study
This is a prospective, open-label, multi-center, single-arm study to evaluate the efficacy and safety of an implantable wireless brain-machine interface (BMI) system in patients with spinal cord injury.
- Trial name
- NCT07603752
- Testing
- WRS
- Where
- China
- Volunteers
- 34 people
- Sponsor
- Shanghai StairMed Technology Co., Ltd.
Intracranial Neoplasm
The Effect of Cerebral Oxygenation on Postoperative Recovery in Intracranial Surgery
The aim of this study was to investigate the effect of cerebral oxygenation on postoperative compilation in intracranial surgery.
- Trial name
- Oxygenation (NCT03714347)
- Testing
- cerebral oxygen monitoring, routine monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Trakya University
Brain Injuries
Efficacy of Nucleo CMP Forte in Traumatic Brain Injury in Pediatrics
Efficacy of Nucleo CMP Forte in Traumatic Brain Injury in Pediatrics
- Trial name
- NCT04499755
- Testing
- Nucleo CMP Forte
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sherief Abd-Elsalam
Dravet Syndrome
A Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Fenfluramine (Hydrochloride) in Infants 1 Year to Less Than 2 Years of Age With Dravet Syndrome
The primary purpose of this study is evaluate the safety and tolerability of fenfluramine hydrochloride (HCl) 0.2 to 0.8 mg/kg/day in infants 1 year to less than 2 years of age with Dravet syndrome.
- Trial name
- ORCHID (NCT06118255)
- Testing
- fenfluramine
- Where
- 12 sites in United States, Belgium and 3 more
- Volunteers
- 25 people
- Sponsor
- UCB BIOSCIENCES, Inc.
Spinal Cord Injury
Intervention Study to Assess the Effects of Moderate and High Intensity Aerobic Training on Physical Capacity and Activity Level in Persons With Incomplete Spinal Cord Injury
The aims of this study are to assess the effects of medium versus high intensity 12-week adjusted training programs on physical capacity in persons with incomplete SCI, early after discharge from primary rehabilitation, and to…
- Trial name
- NCT01903226
- Testing
- High intensity training, Moderate intensity training
- Where
- Norway
- Volunteers
- 30 people
- Sponsor
- Sunnaas Rehabilitation Hospital
Syringomyelia, Chiari Malformation
Development of a Patient-reported Outcome Measure for Chiari Malformation and Syringomyelia
Chiari malformation corresponds to the herniation of cerebellar tonsils into the foramen magnum resulting in obstruction of cerebrospinal fluid circulation, which may eventually lead to the formation of an intramedullary cavity…
- Trial name
- BCS-score (NCT06011226)
- Testing
- focus groups, questionnaire
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Postoperative Delirium, Pediatric Anesthesia
Inflammatory Biomarkers and Postoperative Delirium in Pediatric Circumcision
Postoperative delirium may occur in children after general anesthesia, even following short procedures such as circumcision. Preoperative systemic inflammation has been associated with postoperative delirium in adults, but data…
- Conditions
- Postoperative Delirium, Pediatric Anesthesia, Inflammatory Biomarkers
- Trial name
- NCT07323485
- Testing
- Measurement of Preoperative Inflammatory Biomarkers
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Ankara Etlik City Hospital
Dementia
Establishment of Core Competence and Training Model for Dementia Case Management
The purpose of this study is to develop the core competence and training model for case management of dementia. This study is the second phase of the project.
- Trial name
- NCT05151185
- Testing
- Case Management Service Program
- Where
- Taiwan
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Parkinson Disease
Impact of Customized Respiratory Training on Cardiopulmonary Function in Parkison's Disease
People with PD have lower cardiopulmonary function than their age matched peers. This decline can further impair a person's ability to participate in exercise and daily activities.
- Trial name
- NCT05287243
- Testing
- inspiratory muscle training
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of St. Augustine for Health Sciences
Poliomyelitis
Inactivated Poliomyelitis Vaccine Made From Sabin Strain
This study includes both active and passive safety monitoring in large pupulations for the phase IV safety monitoring study of Inactivated Poliomyelitis Vaccine Made From Sabin Strain (sIPV).
- Trial name
- NCT04220515
- Testing
- Inactivated Poliomyelitis Vaccine Made From Sabin Strain
- Where
- China
- Volunteers
- 49,731 people, healthy volunteers welcome
- Sponsor
- Institute of Medical Biology, Chinese Academy of Medical Sciences
Stroke
Effectiveness of the Cognitive Orientation to Daily Occupational Performance (CO-OP)
The goal of this clinical study is to examine the effectiveness of the Cognitive Orientation to daily Occupational Performance (CO-OP) in adults (18+) with accuired brain injury when applied in Danish rehabilitation context.
- Trial name
- NCT06919315
- Testing
- CO-OP intervention, Usual practice
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Louise Møldrup Nielsen
Peripheral Nerve Injuries
Performance Study of an Artificial Nerve Guide (Reaxon® Nerve Guide) to Treat Digital Nerve Lesions
The purpose of this clinical investigation is to confirm the medium- and long-term safety and performance of the chitosan-based nerve guide (Reaxon® Nerve Guide) in comparison to an autologous nerve graft to bridge nerve defects…
- Trial name
- NCT02459015
- Testing
- Implantation
- Where
- 4 sites in Germany
- Volunteers
- 46 people
- Sponsor
- Medovent GmbH
Major Depressive Disorder, Fibromyalgia
Duloxetine Compassionate Use in Patients Who Have Completed a Previous Neuroscience Duloxetine Clinical Trial
The primary objective of this study is to provide duloxetine to investigators for the treatment of patients who have previously participated in neuroscience duloxetine clinical trials and for whom effective alternative therapy is…
- Conditions
- Major Depressive Disorder, Fibromyalgia, Diabetic Peripheral Neuropathic Pain, Generalized Anxiety Disorder
- Trial name
- NCT00071708
- Testing
- Duloxetine Hydrochloride
- Where
- 13 sites in Australia
- Sponsor
- Eli Lilly and Company
Cervicogenic Headache
Comparative Effects Of Eye-Cervical Re-Education Exercises And Pressure Biofeedback Training Of Deep Cervical Flexors In Cervicogenic Headache
Cervicogenic headache (CGH) is a secondary headache that originates from dysfunction in the upper cervical spine, particularly the atlanto-occipital and C1-C3 segments, and is perceived in one or more regions of the head and/or…
- Trial name
- NCT07526025
- Testing
- Eye cervical re-education exercises, Pressure biofeedback training group
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Foundation University Islamabad
Postoperative Pain After Uterine Fibroid Embolization, Uterine Fibroids (UF)
Transmucosal Uterosacral Electrical Stimulation for Pelvic Pain Relief
This study will test whether gentle electrical stimulation to nerves near the uterus can reduce pelvic pain after uterine fibroid embolization.
- Conditions
- Postoperative Pain After Uterine Fibroid Embolization, Uterine Fibroids (UF), Uterine Fibroids, Pelvic Pain
- Trial name
- TUNES (NCT07501676)
- Testing
- TUNES (Transmucosal Uterosacral Electrical Stimulation)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Weill Medical College of Cornell University
Delirium
Using Eye Mask and Earplugs on Prevention of Delirium
This research is planned as a randomized controlled experimental study to examine the effect of using eye mask and earplugs in preventing delirium with evidence-based nonpharmacological nursing interventions in intensive care…
- Trial name
- NCT05000476
- Testing
- eye mask and earplugs, Nurse Education and Environmental Regulation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Baskent University
Vestibular Diseases, Vestibular Disorder
Effectiveness of Vestibular Electrical Stimulation in Vestibular Rehabilitation
This study aimed to evaluate the effectiveness of the vestibular rehabilitation program applied to patients with chronic unilateral vestibular hypofunction and the vestibular electrical stimulation applied to the trapezius…
- Conditions
- Vestibular Diseases, Vestibular Disorder, Vestibular Vertigo
- Trial name
- NCT06563076
- Testing
- Vestibular Rehabilitation, Vestibular Electrical Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- Ankara City Hospital Bilkent
Stroke, Adrenal Incidentaloma
Association Between Stroke and Adrenal Incidentalomas
Adrenal incidentalomas (AIs) are commonly encountered in transsection imaging which purpose not for suspected adrenal disease. However, part of AIs in patients is associated with Stroke.
- Trial name
- ABSAI (NCT05237817)
- Where
- China
- Volunteers
- 2 people
- Sponsor
- Xuanwu Hospital, Beijing
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