Clinical trials: Nervousness
Stroke, Cognitive Deficits
Self Treatment With an Electronic Device for Cognitive Rehabilitation in Patients With Subacute Stroke
The objective of this study is to evaluate whether the independent use of an electronic device by a patient with stroke outcomes can enhance the effectiveness of rehabilitative treatment for attentional functions compared to…
- Conditions
- Stroke, Cognitive Deficits, Computerized Rehabilitation, Computerized Device
- Trial name
- NCT06755437
- Testing
- Rehabilitation with a computerized device (in the morning), Self-treatment with a computerized device (in the afternoon), self-treatment with pencil-and-paper exercises (in the afternoon)
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Universita di Verona
Muscular Dystrophies
Open Label Study of GSK2402968 in Subjects With Duchenne Muscular Dystrophy
The purpose of this study is to explore long-term safety, tolerability and efficacy of GSK2402968 in DMD subjects who previously participated in either DMD114117 or DMD114044.
- Trial name
- NCT01480245
- Testing
- GSK2402968
- Where
- 59 sites in Argentina, Australia and 22 more
- Volunteers
- 233 people
- Sponsor
- GlaxoSmithKline
Insomnia, Primary
Study of Low Field Magnetic Stimulation (LFMS) on Measures of Sleep
Participants will be recruited and screened through ongoing studies in the sleep and anxiety disorders clinic. Participants with insomnia will be consented to complete several questionnaires, undergo a brief physical exam…
- Trial name
- NCT03050372
- Testing
- LFMS - Active
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Restless Legs Syndrome
Relationship Between Sensory and Motor Systems in Restless Leg Syndrome
This study will explore what occurs between sensory and motor systems in restless legs syndrome (RLS). Patients with RLS have uncomfortable sensations in the legs, usually in the evening or early part of the night.
- Trial name
- NCT00074672
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Pain, Acute, Opioid Use
Femoral Triangle Block With Popliteal Plexus Block Versus Femoral Triangle Block Versus Adductor Canal Block for TKA
In this study we wish to investigate the analgesic effect 3 different nerve block regimes in patients following primary total knee arthroplasty (TKA).
- Conditions
- Pain, Acute, Opioid Use, Analgesia
- Trial name
- NCT04854395
- Testing
- Marcain 5 mg/ml
- Where
- Denmark
- Volunteers
- 165 people
- Sponsor
- Regionshospitalet Silkeborg
High Grade Glioma, Glioma
5-Aminolevulinic Acid (5-ALA) Gliolan®: Usage Increase Proposal for Neurosurgical Procedures in High-Grade Gliomas
The goal of this observational study is to evaluate disease-free survival (DFS) in patients with malignant gliomas undergoing neurosurgical procedures using 5-aminolevulinic acid (5-ALA)-based photodynamic therapy
- Conditions
- High Grade Glioma, Glioma, Glioma, Malignant, Neoplasms, Neuroepithelial
- Trial name
- NCT05850377
- Testing
- 5-Aminolevulinic Acid (5-ALA) Gliolan®, Fluorescence-Guided Surgery using 5-aminolevulinic acid (5-ALA)
- Where
- Ecuador
- Volunteers
- 90 people
- Sponsor
- Sociedad de Lucha Contra el Cáncer del Ecuador
Acute Cerebral Stroke Within 12 Hours for the First Time
Dl-3-n-butylphthalide and Cerebrolysin Treatment in Acute Ischemic Stroke
The investigators conducted a randomized, double-blind, trial enrolled 60 patients within 12 hours of acute ischemic stroke (AIS) in China.
- Trial name
- NCT02149875
- Testing
- Dl-3-n-butylphthalide, Cerebrolysin
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Shanghai 6th People's Hospital
Sensation Disorders, Sensation, Phantom
Prospective Study of Sensation and Satisfaction in Cancer and Transgender Mastectomy Patients
During breast surgery, sensory nerves are cut which may lead to reduced sensation and pain. Surgical reinnervation techniques have been developed with the aim of improving postoperative sensation by preserving the nerves and…
- Conditions
- Sensation Disorders, Sensation, Phantom, Pain, Postoperative, Pain, Chronic
- Trial name
- NCT06094257
- Testing
- Sensory testing
- Where
- 2 sites in United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Cancer, Hearing Loss Ototoxic
The Effect of Cancer Treatments on Speech Perception in Noise, Cognition, and Hearing-Related Quality of Life
The study will assess the effect of cancer treatments on speech perception in noise, cognition, and hearing-related quality of life by monitoring 200 cancer patients receiving standard care for their underlying malignancy.
- Conditions
- Cancer, Hearing Loss Ototoxic, Cognitive Decline, Quality of Life
- Trial name
- CaSPiN (NCT06551857)
- Testing
- Chemotherapy, chemoradiation, radiation therapy
- Where
- Finland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Cerebral Palsy Spastic Diplegia
Comparison of the Effects of Vojta and Bobath Treatment on Gait and Balance in Diplegic Cerebral Palsy
This study aims compare the effects of Vojta verses Bobath therapy on gait in children with diplegic cerebral palsy and to compare the effects of Vojta versus Bobath therapy on balance in children with diplegic cerebral palsy.
- Trial name
- NCT06757101
- Testing
- Vojta Therapy, Bobath Therapy, Combined Vojta and Bobath Therapy
- Where
- Pakistan
- Volunteers
- 72 people
- Sponsor
- Riphah International University
Multiple Sclerosis
Comparison of 1.5T vs. 3T Protocols After Treatment With Glatiramer Acetate (GA)
This study will: Explore whether GA decreases inflammation more on the 3T optimized protocol when compared to the 1.5T standard protocol.
- Trial name
- NCT00937157
- Testing
- Copaxone
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University at Buffalo
Generalized Convulsive Status Epilepticus
Combined Ketamine and Midazolam for Generalized Convulsive Status Epilepticus
Generalized convulsive status epilepticus (GCSE) is a common neurological emergency in children. Benzodiazepines are the recommended first line antiseizure medication (ASMs), but they fail to control seizures in a third of cases.
- Trial name
- Ket-Mid (NCT05779657)
- Testing
- Ketamine, Midazolam
- Where
- Egypt
- Volunteers
- 144 people
- Sponsor
- Sohag University
Spinal Cord Injuries, Self-Management
Improving Self-Management Skills Among People With Spinal Cord Injury
The goal of our study is to evaluate the use of a self-management application ("app") that the investigators have developed to help facilitate self-management among individuals with SCI who live in the community.
- Conditions
- Spinal Cord Injuries, Self-Management, Mobile Application
- Trial name
- MobileApp (NCT03140501)
- Testing
- Mobile application ("app")
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Complex Regional Pain Syndrome
The Effects and Mechanisms of a High CBD Cannabis Extract (BRC-002) for the Treatment of Pain and Health in Complex Regional Pain Syndrome
The aim of this trial is to determine the potential effects and mechanisms of cannabinoid-induced pain relief in complex regional pain syndrome (CRPS).
- Trial name
- NCT06393101
- Testing
- BRC-002
- Where
- 2 sites in United States
- Volunteers
- 52 people
- Sponsor
- University of California, San Diego
Multiple Sclerosis
Effect of Sensory Integration Therapy on Gait Variability and Quality Of Life in Patients With Multiple Sclerosis
This study aims to evaluate the impact of sensory integration therapy on individuals with multiple sclerosis (MS) by examining its effects on gait variability and overall quality of life.
- Trial name
- NCT07390201
- Testing
- Conventional physical therapy program, Sensory integration therapy
- Where
- Egypt
- Volunteers
- 38 people
- Sponsor
- Cairo University
Spinal Cord Injury
Safety and Efficacy of SC0806 (Fibroblast Growth Factor 1 and a Device) in Traumatic Spinal Cord Injury Subjects
This is an open, randomized, rehabilitation-controlled study in subjects with complete Traumatic Spinal Cord Injury, where the active treatment consists of a surgical implantation of SC0806 (a biodegradable device with…
- Trial name
- NCT02490501
- Testing
- SC0806 and rehabilitation, Rehabilitation only
- Where
- Sweden
- Volunteers
- 10 people
- Sponsor
- BioArctic AB
Insomnia, HIV
RCT of CBT for Insomnia With PLWHA
The proposed study will consist of a randomized controlled trial (RCT) comparing a known efficacious treatment for insomnia (CBT-I) to a sleep hygiene (SH) comparison condition.
- Conditions
- Insomnia, HIV, Aids
- Trial name
- NCT02259101
- Testing
- CBT-I Treatment Condition, SH Comparison Condition
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Emory University
Neurofibromatosis Type 1
Ophthalmological Screening and Follow-up of Optic Pathway Gliomas in Children With Neurofibromatosis Type 1.
The goal of this project is to get more insight into the (neuro)ophthalmological characteristics of children with neurofibromatosis type 1.
- Trial name
- NCT02078401
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Acute Ischemic Stroke (AIS), Stroke-Associated Pneumonia (SAP)
Oral Care Strategies for Stroke Patients with Dysphagia
This study aims to evaluate whether combining neuromuscular electrical stimulation (NMES) with oral care can improve swallowing function in patients who have experienced an acute stroke and are dealing with dysphagia (difficulty…
- Conditions
- Acute Ischemic Stroke (AIS), Stroke-Associated Pneumonia (SAP), Dysphagia Following Cerebrovascular Accident
- Trial name
- NCT06692101
- Testing
- oral care, Neuromuscular Electrical Stimulation (NMES)
- Where
- Taiwan
- Volunteers
- 35 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Stroke, Acute
An Open, Study to Assess the Safety of RGTA® (OTR4132) in Patients With Acute Ischemic Stroke (AIS)
RGTA® (ReGeneraTing Agent) are synthetic polysaccharides mimicking extra-cellular matrix scaffold elements and protective agents called Heparan Sulphates (HSPGs). OTR4132-MD is provided as a sterile injectable medical device.
- Trial name
- MATRISS (NCT04083001)
- Testing
- OTR4132MD
- Where
- 3 sites in France
- Volunteers
- 19 people
- Sponsor
- Organ, Tissue, Regeneration, Repair and Replacement
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