Clinical trials: Neural Activity
Post-traumatic Stress Disorder (PTSD), Aggressive Behavior
Treatment of Trauma and Violence in the Townships of South Africa
Escalating violence is omnipresent in South African townships and can be traced back to two core mechanisms: a trauma-related hyper-arousal and a positive rewarding perception of violence.
- Trial name
- NCT02012738
- Testing
- FORNET, CBT, Waiting List Control Group (camp)
- Where
- South Africa
- Volunteers
- 45 people
- Sponsor
- University of Konstanz
Physical Activity
Investigations of the Effects and Associated Neural Mechanisms of Different Exercise in People With Metabolic Syndrome
Metabolic syndrome (MetS) is a risk for many chronic diseases of middle-aged and older adults. Hence, prevention and treatment of MetS is a crucial global health issue.
- Trial name
- NCT05672940
- Testing
- Aerobic plus resistance training, Stretching plus breathing training
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Chronic Obstructive Pulmonary Disease
The Effect of Inhaled Nitric Oxide on Deadspace in COPD
Chronic obstructive pulmonary disease (COPD) is a progressive disease of the respiratory system that generally develops as a result of smoking.
- Trial name
- NCT04069052
- Testing
- Nitric Oxide
- Where
- Canada
- Volunteers
- 13 people
- Sponsor
- Dr. Denis O'Donnell
Subjective Cognitive Decline, Age-Related Cognitive Decline
Lifestyle, Exercise and Diet: The LEAD Study
This study will explore the impact of an exercise and nutrition (EX+NUTR) , relative to exercise alone (EX) intervention, on brain structure and function as well as blood biomarkers in older adults with subjective cognitive…
- Trial name
- LEAD (NCT03056508)
- Testing
- Exercise plus nutrition, Exercise
- Where
- 4 sites in Canada
- Volunteers
- 14 people
- Sponsor
- Rotman Research Institute at Baycrest
Cerebral Palsy, Spina Bifida
Virtual Peer Health Coaching for Adolescents With Disabilities
Participation in physical activity (PA) confers clear physical and psychosocial benefits. Yet, many adolescents with physical disabilities such as cerebral palsy and spina bifida do not engage in regular PA, putting them at…
- Trial name
- NCT05587634
- Testing
- Virtual Peer Health Coaching
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Spaulding Rehabilitation Hospital
Chronic Stroke
Neural Mobilization With Task Based Activities on Upper Limb in Patients With Chronic Stroke.
Stroke is defined as sudden neurological disruption of blood supply to brain. It is most common disease that causes severe disabilities like hemiparesis which is most common motor impairment that leads to persistent upper limb…
- Trial name
- NCT06131827
- Testing
- Neural mobilization, Task based activities
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Riphah International University
Lumbar Radiculopathy
Effect of Active Versus Passive Lower Extremity Neural Mobilization in Lumber Radiculopathy
The aim of this study was to find out the effects of active versus passive lower extremity neuralmobilizations combined with lumbar traction and lumbar mobilization in patients with lumbarradiculopathy.
- Trial name
- NCT04581239
- Testing
- Active neural mobilization, passive neural mobilization
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Riphah International University
Social Acceptance
An fMRI Study of Opioid-related Changes in Neural Activity
The purpose of the study is to explore the effect of blocking opioids on affiliation-related neural activity.
- Trial name
- NCT02818036
- Testing
- Naltrexone
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Tristen Inagaki
Parkinson Disease, Gait Disorders, Neurologic
Investigating Neural Biomarkers for Gait in Parkinson's Patients
This observational study's main goal is to learn more about the neural mechanisms during movement in Parkinson's disease. Furthermore, it aims to inspire personalised treatment options.
- Trial name
- NCT05820074
- Testing
- Neural Activity Recording, Movement Parameter Recording, Neuromodulation
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Autonomic Nervous System, Cardiovascular Outcomes
Impact of Caffeine Intake on Autonomic Parameters in the Exercise of Strength
The objective of this study was to evaluate the variability of the heart rate of exercise physicists with and without caffeine intake.
- Trial name
- NCT03899675
- Testing
- Caffeine
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Pernambuco
Non-specific Low Back Pain
Dose Response of Neural Mobilization on Hamstring Flexibility in Low Back Pain
This study will be a randomized control trial and will be conducted in Riphah International Hospital, National orthopedic and specialist hospital, Riphah international hospital and Chambeli institute of physiotherapy.
- Trial name
- NCT05101200
- Testing
- High Dose Neural Mobilization Technique, Low Dose Neural Mobilization Technique
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Riphah International University
Stroke
A Study Exploring Brain Activity in Relation to Sensory Arm Impairments in the Early Stages of Stroke
This clinical study is organized for people with stroke often experience difficulties with their sensation in their upper limb. New technologies may be able to help these important problems.
- Trial name
- NCT03407547
- Testing
- Electroencephalography
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Stroke
A Closed Loop Neural Activity Triggered Stroke Rehabilitation Device
The purpose of this research is to determine if two non-invasive brain stimulation techniques, muscle stimulation of the arm and neuro-stimulation through the tongue, can increase the extent of stroke recovery.
- Trial name
- NCT02098265
- Testing
- Functional Electric Stimulation (FES), Behavioral Assessments, Magnetic Resonance Imaging
- Where
- United States
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Cognition, Brain Activity
Human Neural Correlates of Multi-Timescale Inference
Adult epilepsy patients who are undergoing intracranial monitoring will participate in a simple behavioral task during the clinical recording period.
- Trial name
- NCT07606469
- Testing
- Decision-making task, eye tracking
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Colorado, Boulder
Healthy
Chatbot Intervention Effects on Resting-State Brain Function in Anhedonia
The main aim of the present study is to investigate the effects of a Motivational Interviewing-based artificial intelligence chatbot on resting-state brain function in college students with elevated anhedonia and depressive…
- Trial name
- NCT07665216
- Testing
- MI Chatbot Interaction, Active Control Chatbot Interaction
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Human Neural Cells Functioning
Inside a Neuron - Ex Vivo Evaluation of Cerebral and Cerebellar Neuronal Activity.
Understanding the functioning of human neurons has always been a key element, especially with regard to the translation of the inputs they receive into actions that determine human behavior.
- Trial name
- INSANE (NCT06896331)
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Perinatal Hypoxia, Dopamine
Measuring Brain Activity of School Age Children
This observational study will investigate whether differences in birth events and oxygen levels during the newborn period affects the brain activity of children during the middle childhood years.
- Conditions
- Perinatal Hypoxia, Dopamine, Neurobehavioral Manifestations
- Trial name
- NCT03407729
- Testing
- Magnetic Resonance Imaging, Cognitive Performance Testing
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Cognitive Change
Impact of Challenging Engagement on Cognition in Older Adults
The study will enroll 90 participants in the "Impact of Challenging Engagement" study and assign them to one of three groups: high-demand photography, moderate-demand photography, and active placebo.
- Trial name
- engAGE (NCT03962439)
- Testing
- High-Demand Photography, Moderate-Demand Photography, At-Home Engagement
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Dallas
Knee Pain, Patellofemoral Pain
A Comparison of Two Exercise Programs on Knee Motor Control
Pain at the front of the knee is a common condition treated by physical therapists. Treatment may consist of generalised strengthening exercises directed at the quadriceps muscle or specific retraining aimed at restoring motor…
- Trial name
- NCT00662493
- Testing
- Motor control retraining program, Quadriceps strengthening program
- Where
- Australia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Melbourne
Tetraplegia, Spinal Cord Injury
Cortical Recording and Stimulating Array Brain-Machine Interface
The purpose of this research study is to demonstrate the safety and efficacy of using two CRS Arrays (microelectrodes) for long-term recording of brain motor cortex activity and microstimulation of brain sensory cortex.
- Conditions
- Tetraplegia, Spinal Cord Injury, Brainstem Stroke, Brachial Plexus Injury
- Trial name
- CRS-BMI (NCT01894802)
- Testing
- Implantation of CRS Arrays
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Michael Boninger