Clinical trials: Neural Activity
Alzheimer Disease
Neural Mechanisms of Clinically Designed Improvisatory Music for Alzheimer's Disease
Clinically Designed Improvisatory Music (CDIM) is a form of improvised music based on calm-inducing sound parameters which brought relief to our cohort of neurology patients.
- Trial name
- NCT05477862
- Testing
- Clinically Designed Improvisatory Music
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Posttraumatic Stress Disorder
Impact of Cognitive Behavioral Therapy on PTSD-CVD Link
This is a pilot randomized controlled trial to assess the impact of a first-line treatment for posttraumatic stress disorder (PTSD) (Cognitive Processing Therapy; CPT) versus waitlist control on mechanisms of cardiovascular…
- Trial name
- NCT06429293
- Testing
- Cognitive processing therapy
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Massachusetts General Hospital
Acoustic Stimulation, Parkinson Disease
Rhythmic Auditory Stimulation on Neural Activity During Finger-tapping in PD Patients
Introduction Bradykinesia (i.e., slow movements) is one of the most prominent symptoms of Parkinson's disease (PD) and has a negative impact on quality of life.
- Conditions
- Acoustic Stimulation, Parkinson Disease, Electroencephalography
- Trial name
- NCT05839821
- Testing
- noF-noRAS, F-noRAS, noF-100RAS
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Height Phobia, Fear of Heights
Changes in Brain Activity (Functional MRI Study) Before and After Behavioral Therapy of Height Phobia
We are interested in investigating the functional brain abnormalities of height phobia. Subjects will be have a functional MRI scan before and after a course of treatment with behavioral therapy.
- Trial name
- NCT00302978
- Testing
- Behavior therapy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Parkinson Disease, Deep Brain Stimulation
The Impact of Exercise on Subthalamic Nucleus Neural Activity in Parkinson's Disease
Fifteen PwPD who have undergone DBS surgery and utilize the Percept system will complete a FE and VE exercise session on a stationary cycle while Off antiparkinsonian medication.
- Trial name
- NCT05905302
- Testing
- Forced and Voluntary Exercise
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Jay Alberts
Elevated Blood Pressure
Mindfulness and Neural Cardiovascular Control in Humans
This study evaluates the impact of mindfulness-based stress reduction (MBSR) on sympathetic nerve activity and arterial stiffness.
- Trial name
- NCT03626363
- Testing
- Stress Management
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Michigan Technological University
Neural Connectivity
Neural Activation and Connectivity in Response to Exercise and Cognitive Training
The goal of this pilot study is to evaluate whether healthy, sedentary older adults have increased activation of specific brain areas, in response to exercise and cognitive training, in comparison to a control group, and whether…
- Trial name
- NAC (NCT01603771)
- Testing
- Blood Oxygen Level Dependent (BOLD) functional magnetic imaging (fMRI)
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Inadequate; Pulmonary Ventilation, Newborn, Infant, Very Low Birth Weight
Nasal Noninvasive NAVA in the Very Low Birth Weight Infant
The purpose of this study is to determine if a new type of mechanical ventilation, or breathing machine (called neurally adjusted ventilatory assist or NAVA), will provide additional support to infants who were born prematurely.
- Trial name
- NCT01785563
- Testing
- Nasal NIV-NAVA
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Tarah T Colaizy
Cognitive Health, Healthy Aging
Successful Aging and Enrichment (SAGE)
Progress has been made in understanding the impact of different kinds of structured intervention programs in improving cognitive processing and performance in older adults, and in determining whether there is electrophysiological…
- Trial name
- SAGE (NCT05128396)
- Testing
- Cognitive Stimulation, Mindfulness training, Physical Activity
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Overweight, Obesity
The Influence of Acute Continuous Exercise and Adiposity on Appetite Hormones and Neural Correlates of Visual Food Cues
Exercise increases energy expenditure and impacts appetite and energy intake. Some appetite-related hormones such as oxyntomodulin suppress appetite whilst other hormones such as ghrelin stimulate appetite.
- Trial name
- ACECRAVE (NCT06849050)
- Testing
- Acute continuous exercise
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Multiple Sclerosis
Promoting Aerobic Training in Multiple Sclerosis
Multiple sclerosis (MS) is a chronic neurological disease characterized by inflammation and degeneration within the central nervous system.
- Trial name
- NCT05212805
- Testing
- Aerobic exercise, Task-oriented upper-limb training, Sport events participation
- Where
- Italy
- Volunteers
- 62 people
- Sponsor
- Fondazione Italiana Sclerosi Multipla
Alzheimer's Disease
Statins in Cerebral Blood Flow and Neuronal Activity--A Pilot Study
Specific Aim: Demonstrate that statins have an effect on cerebral blood flow and neuronal activity
- Trial name
- NCT03411291
- Testing
- MRI, MR Spectroscopy, MR Perfusion
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Cedars-Sinai Medical Center
Neuropathy, Diabete Mellitus
Comparison of Active vs Passive Neural Mobilizations Effects in Improving Burning Pain, Muscular Strength, and Range of Motion in Patients With Diabetic Neuropathy
Randomized controlled trial evaluating active and passive neurodynamic techniques for diabetic neuropathy. Sample size: 60 patients (30 per group), aged 40 to 65 years, diagnosed with diabetes mellitus.
- Conditions
- Neuropathy, Diabete Mellitus, Diabetic Neuropathy
- Trial name
- RCT (NCT07141992)
- Testing
- Active Neural Mobilzations, Passive Neural Mobilzations
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Dow University of Health Sciences
Multiple Sclerosis
Examining the Neural Effects of a Behavioral Intervention for Physical Activity in Multiple Sclerosis
Multiple sclerosis [MS] is a prevalent neurological disease that is the leading cause of irreversible neurological disability among young women and the second leading cause of disability among young men in the United States.
- Trial name
- BIPAMS-Brain (NCT04496804)
- Testing
- Behavioral Intervention for Physical Activity in MS (BIPAMS), Wellness for MS (WellMS)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Alabama at Birmingham
Schizophrenia Disorders, Psychosis
Magnetoencephalography in Psychosis Program
This research involves the examination of speech, thinking patterns and symptoms and recordings from brain's activity in patients with schizophrenia.
- Trial name
- MEGPSY (NCT06978881)
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Douglas Mental Health University Institute
Acute Brain Injury, Traumatic Brain Injury
Connectivity and Neural Signatures of Consciousness in Unresponsive States
The CONSCIUS study is a prospective, interventional study including patients with acute brain injury and impaired consciousness implanted with intracranial electrodes.
- Conditions
- Acute Brain Injury, Traumatic Brain Injury, Consciousness Disorders, Seizures
- Trial name
- CONSCIUS (NCT06426615)
- Testing
- Intracranial electrodes
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Metabolic Syndrome X
Sympathetic Activity in Individuals With the Metabolic Syndrome: Benefits of Lifestyle Interventions
An abdominal distribution of fat is associated with the greatest heart disease risk, because commonly, several risk factors of metabolic origin (high blood pressure, unfavourable cholesterol profile, elevated blood sugar…
- Trial name
- NCT00163943
- Testing
- Dietary weight loss +/- aerobic exercise
- Where
- Australia
- Volunteers
- 66 people
- Sponsor
- Bayside Health
Stress, Anxiety
Minerals and Botanicals for Acute Stress
The objective of this acute intervention study is to examine the potential of minerals combined with botanicals to demonstrate unique and synergistic effects on oscillatory brain activity, cognitive performance, and stress…
- Trial name
- NCT03262376
- Testing
- Minerals + Vitamins, Botanical A, Botanical B
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Neurogenic Bladder, Neurogenic Bowel
The Role of Active Administration of Peristeen Bowel Evacuation for the Management of Urinary Tract Infection
This study investigates whether active use of transanal irrigation (Peristeen®) effectively manages urinary tract infection among patients with the diagnosis of neurogenic bladder.
- Conditions
- Neurogenic Bladder, Neurogenic Bowel, Spina Bifida, Fecal Incontinence
- Trial name
- NCT04815226
- Testing
- Peristeen Transanal Irrigation
- Where
- South Korea
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Stroke
Neurofeedback for Stroke Rehabilitation
Real-time neurofeedback aims to alter brain activation patterns through online feedback of ongoing brain activity using magnetic resonance imagining (MRI).
- Trial name
- NCT03775915
- Testing
- Neurofeedback
- Where
- United Kingdom
- Volunteers
- 27 people
- Sponsor
- University of Oxford