Clinical trials: Neural Injury
Brain Injury
Neural Bases of Cognitive Rehabilitation for Brain Injury
Some of the most common and disabling consequences of brain injury are deficits in cognition, such as difficulty with sustained attention, memory, organization, and goal management.
- Trial name
- NCT01120756
- Testing
- Goal-oriented attentional self-regulation, Brain Health Education
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Osteoporosis, Osteoporotic Fractures
Osteoporotic Precisely Screening Using Chest Radiograph and Artificial Neural Network (OPSCAN)
Artificial Intelligence-assisted Diagnosis and Prognostication in Osteoporosis Using Chest X-ray
- Trial name
- NCT05721157
- Testing
- AI-enabled Chest X-ray-based Screening Tool
- Where
- Taiwan
- Volunteers
- 4,912 people
- Sponsor
- National Defense Medical Center, Taiwan
Carpal Tunnel Syndrome
In Patients With Carpal Tunnel Syndrome, Median Nerve Conduction is Evaluated After Nerve Mobilizations
This project is linked to the line of research on carpal tunnel syndrome, of the PhysiUZerapy research group, belonging to the University of Zaragoza.
- Trial name
- NCT06399484
- Testing
- Manual mobilizations of the median nerve, Wrist movements
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universidad de Zaragoza
Pain, Infection
Safety of Coronectomy vs Excision of Wisdom Teeth
The purpose of this study is to compare the surgical complications and neurosensory disturbance of coronectomy and conventional excision of wisdom teeth with roots in close proximity to inferior alveolar nerve.
- Conditions
- Pain, Infection, Alveolar Nerve Injury
- Trial name
- coronrct (NCT00752284)
- Testing
- Coronectomy, Total Excision
- Where
- China
- Volunteers
- 349 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Peripheral Nerve Injuries
Mirror Therapy Integrated With Electrical Stimulation for Cortical Modulations
Peripheral nerve injury is common and can result in loss of sensation and motor function, reduced quality of life, and prolonged time to return to work.
- Trial name
- NCT06209801
- Testing
- Mirror therapy, Neuromuscular electrical stimulation, Motor imagery
- Where
- 2 sites in Taiwan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Peripheral Nerve Injuries
Registry of Avance® Nerve Graft's Utilization and Recovery Outcomes Post Peripheral Nerve Reconstruction
This study is a registry of general use of Avance Nerve Graft and is intended to evaluate the uses, response rates, and safety of Avance Nerve Graft in the real-life clinical setting.
- Trial name
- RANGER® (NCT01526681)
- Testing
- Processed Human Nerve Graft, Standard Treatment, Autogenous Nerve Graft, Direct Suture, etc., Autogenous Nerve Graft
- Where
- 49 sites in United States, Austria and 2 more
- Volunteers
- 3,126 people
- Sponsor
- Axogen Corporation
PTSD, Adolescent
Neural Connectivity During Therapy for Adolescent PTSD
Posttraumatic stress disorder in adolescence impairs neurobiological networks underlying cognitive, social and emotional skills.
- Conditions
- PTSD, Adolescent, Psychological Trauma
- Trial name
- NCT05423444
- Testing
- TF-CBT, TAU
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Tennis Elbow
Adding Neural Mobilization to Mulligan Technique for Treatment of Patients With Chronic Tennis Elbow
The study aimed to assess the combined effect of neural mobilization and mulligan technique on pain ,functional disability and grip strength in patients with tennis elbow
- Trial name
- NCT06765798
- Testing
- Group A : receive neural mobilization for radial nerve , mulligan mobilization with movement and conventional Therapy, Group B receive neural mobilization for radial nerve and conventional, Group C receive Mulligan mobilization with movement and conventional
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Safaa Radi Saber
Digital Nerve Injury, Nerve Injury
Evaluating Therapeutic Electrical Stimulation to Improve Nerve Healing After Surgical Repair of Digital Nerve Injuries
The goal of this clinical study is to evaluate if a period of electrical stimulation delivered during the surgical repair procedure can speed up nerve healing.
- Conditions
- Digital Nerve Injury, Nerve Injury, Nerve Reconstruction, Nerve Trauma
- Trial name
- FASTR-TEN (NCT06867185)
- Testing
- Brief Electrical Stimulation Therapy, Digital Nerve Repair
- Where
- 5 sites in United States
- Volunteers
- 60 people
- Sponsor
- Checkpoint Surgical Inc.
Spinal Cord Injury
Testosterone and Neural Function in Men With Spinal Cord Injury
Spinal cord injury (SCI) disrupts the nerves controlling movement, along with those that regulate functions like heart rate and blood pressure (known as the autonomic nervous system, or ANS).
- Trial name
- NCT06130449
- Testing
- Natesto testosterone intranasal gel, Ayr Saline Nasal Gel
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Neurosensory Function of Inferior Alveolar Nerve
Assessment of Nerve Function After Mandible Surgery With a Modified Bilateral Sagittal Split Osteotomy Technique
Several technical modifications based on the anatomical position of the neurovascular bundle and its bony mandibular canal have been developed, aiming to prevent injury to the intraalveolar nerve We hypothesized that the…
- Trial name
- NCT02634840
- Testing
- bilateral sagittal split osteotomy
- Volunteers
- 57 people
- Sponsor
- Chang Gung Memorial Hospital
Traumatic Brain Injury
Relationship Between Attention and Emotional Regulation Post-Traumatic Brain Injury (TBI)
The purpose of this pilot study is to investigate the relationship between attention and emotional function post-Traumatic Brain Injury (TBI) in an effort to better understand the cognitive mechanisms of emotional processing in…
- Trial name
- NCT01681589
- Testing
- Transcranial Direct Current Stimulator (TDCS), Control Group, Healthy Control Group
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Nerve Block, Nerve Blocks
Blast-related Regional Anaesthesia and Peripheral nerVe Injury Evaluation
This randomized study will examine whether ultrasound-guided regional anaesthesia (a nerve block) contributes to new or worsening peripheral nerve problems after blast-related limb trauma.
- Conditions
- Nerve Block, Nerve Blocks, Nerve Injury, Blast Injury
- Trial name
- BRAVE (NCT07879508)
- Testing
- Standardized Multimodal Analgesia, Ultrasound-Guided Regional Anaesthesia
- Volunteers
- 150 people
- Sponsor
- Ukrainian Society of Regional Anesthesia and Pain Therapy
Digital Nerve Injury
SECURE Post-Market Study
The purpose of this post-market study is to generate post-market, real- world evidence on the safety and performance of COAPTIUM® CONNECT with TISSIUM® LIGHT for the atraumatic sutureless repair of acute digital (sensory)…
- Trial name
- SECURE PMS (NCT07756489)
- Testing
- COAPTIUM® CONNECT
- Volunteers
- 65 people
- Sponsor
- Tissium
Nerve Injury, Peripheral Nerve Injuries
Promoting Healing of Injured Nerves With Electrical Stimulation Therapy
This study is evaluating a new therapeutic use of electrical stimulation to promote nerve healing and improve functional recovery following surgical intervention for peripheral nerve injury in arm.
- Conditions
- Nerve Injury, Peripheral Nerve Injuries, Peripheral Nerve Injury Upper Limb, Nerve Palsy
- Trial name
- PHINEST (NCT05884125)
- Testing
- Checkpoint BEST System
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Checkpoint Surgical Inc.
Carpal Tunnel Syndrome
Comparative Effect of Scaphoid, Hamate Mobilization and Neural Mobilization in Patients With Carpal Tunnel Syndrome
To rule out the effects bone mobilization and neural mobilization in Carpal Tunnel Syndrome.
- Trial name
- NCT05261880
- Testing
- Neural mobilization, Scaphoid , hamate mobilization
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Riphah International University
Nerve Injury, Orofacial Pain
Post-traumatic Neuropathy of the Trigeminal Nerve
This is retrospective research mainly aims to determine the patterns of symptoms, clinical and radiological findings and outcomes in patients with trigeminal neuropathy following trauma or iatrogenic damage and how this…
- Conditions
- Nerve Injury, Orofacial Pain, Trigeminal Nerve Injuries, Trigeminal Neuropathy
- Trial name
- NCT04612855
- Testing
- Groupwise comparison of primary and secondary outcomes
- Where
- Belgium
- Volunteers
- 1,333 people
- Sponsor
- KU Leuven
PTSD
Efficacy and Neural Mediators of Response to Trauma Management Therapy for PTSD
Social difficulties are serious and frequent complicating factors in the treatment of post-traumatic stress disorder (PTSD). To better understand how treatment of post-traumatic stress disorder impacts neural mechanisms of social…
- Trial name
- NCT03449576
- Testing
- Trauma Management Therapy, Exposure Therapy with Psychotherapy group
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- VA Office of Research and Development
MTBI - Mild Traumatic Brain Injury
Retraining Neural Pathways Improves Cognitive Skills After A Mild Traumatic Brain Injury
The proposed study tests the efficacy (Phase II) of 36 or 54 30-minute training sessions of PATH neurotraining followed by digit memory exercises to improve working memory, processing speed and attention in mTBI patients rapidly…
- Trial name
- NCT03655782
- Testing
- PATH + DigitMemory (DM) neurotraining
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- Perception Dynamics Institute
Dexterity, Tendon Injuries
Does Restriction of the Dominant Hand Due to Injury Improve Non-Dominant Hand Function?
Hand injuries result in the restriction of use of the injured hand within a splint or a plaster during the first 6 weeks which is critical for tissue healing.
- Conditions
- Dexterity, Tendon Injuries, Fractures, Nerve Injury
- Trial name
- NCT06783205
- Testing
- Restriction of the Dominant Hand Due to Splint Use
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Gazi University