Clinical trials: Neuralgia Peripheral
Neuropathic Pain
Study of NMDA Antagonists and Neuropathic Pain
The aim of this study is to evaluate if memantine or dextromethorphan gave in relay to ketamine maintains or induces a decrease of pain intensity.
- Trial name
- NMDA (NCT01602185)
- Testing
- Dextromethorphan (drug used like antitussive), Memantine (drug used in Alzheimer's disease)
- Where
- France
- Volunteers
- 7 people
- Sponsor
- University Hospital, Clermont-Ferrand
Neuropathic Pain, Phantom Limb Pain
Mindful SensoriMotor Therapy With Brain Modulation in Highly Impaired Extremities
Brief summary: This single-arm, pilot clinical investigation aims to evaluate Mindful SensoriMotor Therapy (MSMT) enhanced with brain modulation as a treatment of pain due to sensorimotor impairment, such as Phantom Limb Pain…
- Trial name
- NCT04897425
- Testing
- Mindful SensoriMotor Therapy Enhanced with Brain Modulation
- Where
- Sweden
- Volunteers
- 8 people
- Sponsor
- Chalmers University of Technology
COVID-19 Pandemic, ICU
Chronic Pain in COVID-19 Patients Discharged From Intensive Care Unit
More than six million French were affected by SARS-COV2 epidemic. About 20% of infected peoples were hospitalized, and about 5% were admitted to the intensive care units (ICU) for severe SARS-COV2 acute respiratory distress…
- Conditions
- COVID-19 Pandemic, ICU, Pain, Chronic, Post Intensive Care Unit Syndrome
- Trial name
- NCT04940208
- Testing
- Pain and neuropsychological questionnaires, Quantitative Sensory testing
- Where
- 3 sites in France
- Volunteers
- 143 people
- Sponsor
- Mikhail Dziadzko, MD, PhD
Pain
Selective Neurectomy and Mesh Removal for Chronic Postherniotomy Pain
Chronic postherniotomy pain affects every day activities in 5-8% of patients. However, no established treatment for this pain syndrome exists and previous reports on the effect of surgical intervention suffer from methodological…
- Trial name
- NCT00627289
- Where
- 2 sites in Denmark
- Volunteers
- 21 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Pain Management, Psychiatric Comorbidities
Accelerated Dual-Protocol rTMS for Refractory Trigeminal Neuralgia
Brief Summary The goal of this clinical trial is to learn if an accelerated, dual-protocol high-frequency repetitive transcranial magnetic stimulation (rTMS) intervention can treat and achieve long-term pain relief (analgesia) in…
- Trial name
- rTMS-TN-M1 (NCT07908420)
- Where
- Bulgaria
- Volunteers
- 192 people
- Sponsor
- Galileo Medical Center
Neuropathic Pain, Reflex Sympathetic Dystrophy
Effects of Vaporized Marijuana on Neuropathic Pain
This study theorized that a low dose of vaporized cannabis could alleviate nerve injury pain.
- Conditions
- Neuropathic Pain, Reflex Sympathetic Dystrophy, Peripheral Neuropathy, Post-herpetic Neuralgia
- Trial name
- NCT01037088
- Testing
- Mild dose cannabis, Low dose cannabis, Cannabis
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of California, Davis
Cervical Radiculopathy, Cervical Disc Herniation
Clinical Outcomes of Magnesium Sulfate in Cervical Interlaminar Epidural Steroid Injection
This single-center observational comparative cohort study evaluates clinical outcomes following two cervical interlaminar epidural steroid injection protocols used in routine care for chronic cervical radicular pain due to…
- Trial name
- NCT07788820
- Testing
- Magnesium Sulfate, Normal Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 123 people
- Sponsor
- Marmara University
Osteoarthritis, Knee
Effects of Central Sensitization on Response to Conventional Physical Therapy in Patients With Knee Osteoarthritis
The aim of this study was to investigate the relationship between central sensitization (CS) and poor response to conventional physical therapy in patients with knee osteoarthritis (OA) by evaluating clinical parameters of pain…
- Trial name
- NCT05518097
- Testing
- Conventional physical therapy program
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Ankara University
Postherpetic Neuralgia
Involvement of Reorganization of Cerebral Functional Connectivity in the Process of Transition to Postherpetic Neuralgia
Postherpetic neuralgia(PHN) is a chronic neuropathic pain syndrome which persists more than 3 months after the resolution of the acute shingles episode.
- Trial name
- NCT03106896
- Volunteers
- 75 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Diabetic Peripheral Neuropathic Pain
Chronic Pain Master Protocol (CPMP): A Study of LY3016859 in Participants With Diabetic Peripheral Neuropathic Pain
This study is being done to test the safety and efficacy of the study drug LY3016859 for the treatment of diabetic peripheral neuropathic pain.
- Trial name
- NCT04476108
- Testing
- LY3016859
- Where
- 36 sites in United States, Puerto Rico
- Volunteers
- 125 people
- Sponsor
- Eli Lilly and Company
Diabetic Peripheral Neuropathy (DPN), Diabetic Peripheral Neuropathic Pain (DPNP)
Using Lymphovenous Bypass to Alleviate Diabetic Peripheral Neuropathy
Diabetes is a metabolic disease characterized by high blood sugar levels due to a lack of insulin. Long-term metabolic disorders can cause structural and functional changes in many organs, mainly affecting the vascular system…
- Conditions
- Diabetic Peripheral Neuropathy (DPN), Diabetic Peripheral Neuropathic Pain (DPNP), Diabetic Foot Ulcer
- Trial name
- LVB ease DPN (NCT07126197)
- Testing
- lymphovenous bypass at diseased foot dorsum
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Pulsed Radiofrequency, Lumbar Radiculopathy
High-Voltage Pulsed Radiofrequency of the Lumbar Dorsal Root Ganglion for the Treatment of Chronic Lumbar Radicular and Neuropathic Pain; A Prospective, Doble-blinded and Randomized Controlled Trial
The management of chronic lumbar radicular and neuropathic pain is complex and the treatment success rates are low. Pulsed radiofrequency (PRF) has been described in these cases.
- Trial name
- Radiofrequency (NCT06264297)
- Testing
- Radiofrequency
- Where
- Spain
- Volunteers
- 98 people
- Sponsor
- Consorci Sanitari de Terrassa
Neuropathic Pain, Corneal Disease
Evaluation of the Clinical Efficacy and Mechanisms of Cord Plasma Eye Drops in the Treatment of Neuropathic Corneal Pain
The goal of this clinical trial is to investigate the efficacy and work of action of cord plasma eye drops in the treatment of neuropathic corneal pain (NCP).
- Trial name
- NCT07566806
- Testing
- Cord plasma eye drops
- Where
- Singapore
- Volunteers
- 20 people
- Sponsor
- Singapore Eye Research Institute
Piriformis Syndrome
Interfascial Hydrodissection Added to Ultrasound-Guided Piriformis Injection for Piriformis Syndrome
The gluteus maximus overlies the piriformis muscle and forms a broad fascial interface with it. Restricted movement, increased tension, or adhesions between these tissue layers may contribute to persistent buttock pain in…
- Trial name
- NCT07813455
- Testing
- Ultrasound-Guided Piriformis Injection, Ultrasound-Guided Interfascial Hydrodissection, Standardized Home-Based Piriformis Stretching Program
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Haydarpasa Numune Training and Research Hospital
Neuropathic Pain, Spinal Cord Injury
Reliability and Validity of the Turkish Version of the SCIPI
Pain after spinal cord injury (SCI) is common, with the majority of individuals experiencing chronic pain and a significant portion reporting severe pain that interferes with their daily lives.
- Trial name
- NCT06990243
- Testing
- Evaluation Group
- Volunteers
- 40 people
- Sponsor
- Istinye University
Bursa; Tuberculous, Hip Bursitis
Trochanteric Bursal Repair After a Total Hip Replacement - Are There Benefits During the First 90 Days
During total hip arthroplasty surgery, the trochanteric bursa is routinely excised. This anatomical structure, which functions as a soft tissue barrier, is generally recommended for removal as it facilitates the surgical…
- Conditions
- Bursa; Tuberculous, Hip Bursitis, Deep Gluteal Syndrome, Hip Disease
- Trial name
- NCT06553508
- Testing
- Trochanteric bursa repaired, Trochanteric bursa unrepaired
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people
- Sponsor
- Ankara City Hospital Bilkent
Neuropathic Pain
Safety And Efficacy In Long Term Use Of Lyrica (Regulatory Post Marketing Commitment Plan)
The objective of this investigation is to evaluate the safety and efficacy of long term use with Lyrica in medical practice. Also, occurrence of unknown and known adverse drug reactions (ADRs) in subjects treated with Lyrica will…
- Trial name
- RAINBOW-L (NCT01279850)
- Testing
- Pregabalin (Lyrica) capsule
- Volunteers
- 891 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Peripheral Neuropathy, Pain
Teleconsultations Hypnosis Sessions for Patients With Peripheral Chronic Neuropathic Pain
The aim of this study is to assess the feasibility of hypnosis sessions performed in teleconsultations and led by a nurse, for patients with peripheral chronic neuropathic pain.
- Trial name
- HYPTEC (NCT05623449)
- Testing
- Clinical examination, Anxiety and Depression Scale (HAD), pain scale
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Bordeaux
Neuropathic Pain, Neuropathy;Peripheral
Posterior-superior Insula Deep Brain Stimulation in Refractory Peripheral Neuropathic Pain Patients
This study evaluates the long term pain relief after deep brain stimulation on posterior-superior insula (PSI) in patients with refractory peripheral neuropathic pain who responded to real but not to sham non-invasive stimulation…
- Trial name
- PSI-DBS (NCT04279548)
- Testing
- Deep Brain Stimulation
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- University of Sao Paulo
Neuropathic Pain
Symptomatic Treatment Of Patients With Neuropathic Pain With LYRICA
A Non-Interventional, Post-Marketing Surveillance (NI-PMS) study whose objectives were to assess the impact of pregabalin on subjects' pain, quality of sleep, and their general wellbeing, as well as the tolerance and safety of…
- Trial name
- NI-PMS (NCT00843284)
- Testing
- Pregabalin
- Volunteers
- 691 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
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