Clinical trials: Neuralgia Peripheral
Phantom Limb Pain After Amputation, Chronic Pain Due to Injury
Negative Pressure Wound Therapy as a Predictor of Persistent Pain After War-Related Trauma
War-related trauma frequently causes complex soft tissue injuries that require repeated surgical treatment and advanced wound management techniques such as Negative Pressure Wound Therapy (NPWT).
- Conditions
- Phantom Limb Pain After Amputation, Chronic Pain Due to Injury, Postoperative Pain, Trauma (Including Fractures)
- Trial name
- NPWT-Pain Stud (NCT07475897)
- Where
- Ukraine
- Volunteers
- 150 people
- Sponsor
- Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans)
Sciatica
Effect of Somatosensory Motor Control With and Without Kinesio Tape in Patients With Sciatica
Sciatica can be defined as a radicular pain that runs through the sciatic nerve from the lower back to the lower limbs and also may be associated with weakness or numbness in the muscles.
- Trial name
- NCT07756905
- Testing
- somatosensory motor control exercises, Kinesiology taping, and conventional Treatment, somatosensory motor control and conventional Treatment
- Where
- Pakistan
- Volunteers
- 58 people
- Sponsor
- Riphah International University
Neuropathy, Painful, Chemotherapy-induced Peripheral Neuropathy
Lidocaine for Oxaliplatin-induced Neuropathy
Oxaliplatin-induced neuropathy is a major dose-limiting side effect in patients with colorectal cancer treated with the FOLFOX chemotherapy regimen.
- Conditions
- Neuropathy, Painful, Chemotherapy-induced Peripheral Neuropathy, Colorectal Cancer
- Trial name
- NCT03254394
- Testing
- Lidocaine Hydrochloride, FOLFOX regimen
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Washington University School of Medicine
Patient With Neuropathic Pain
Impact of Oral Magnesium on Neuropathic Pain
Use lay language. The aim of this study is to evaluate on pain scores (neuropathic pain questionnaire and pain numeric scale) and on quality of life, the effect of oral magnesium intake on patients with neuropathic pain comparing…
- Trial name
- NCT01121653
- Testing
- Magnogene ® (magnesium)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Clermont-Ferrand
Neuropathic Pain, Multiple Sclerosis
Efficacy and Safety Evaluation of Nabilone as Adjunctive Therapy to Gabapentin for the Management of Neuropathic Pain in Multiple Sclerosis
The purpose of this study is to determine whether nabilone (Cesamet) when used as an adjunctive agent with gabapentin (Neurontin) provides significantly improved pain relief over gabapentin alone for the management of neuropathic…
- Trial name
- NCT00480181
- Testing
- nabilone
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Manitoba
Chronic Radicular Back Pain, Lumboischialgia
High-tone External Muscle Stimulation for Pain Reduction
Sciatica is a common pain problem that affects not only the patient but also constitutes a socioeconomic burden and thus affects the whole society. So far, current pharmacologic therapies are inadequate for many patients.
- Conditions
- Chronic Radicular Back Pain, Lumboischialgia, Cervico Brachialgia
- Trial name
- HTEMS (NCT02151565)
- Testing
- HTEMS, TENS
- Where
- 2 sites in Germany
- Volunteers
- 100 people
- Sponsor
- West German Center of Diabetes and Health
Neuropathic Pain
Efficacy and Safety of Praga Formulation in the Treatment of Neuropathic Pain
The purpose of this study is to evaluate the efficacy and safety of Praga formulation in the treatment of neuropathic pain.
- Trial name
- NCT04666714
- Testing
- Praga formulation, Pregabalin 75mg, Pregabalin 150mg
- Where
- Brazil
- Volunteers
- 136 people
- Sponsor
- EMS
Postherpetic Neuralgia
A Study to Evaluate the Safety and Efficacy of Topically Applied TV 45070 Ointment in Patients With Postherpetic Neuralgia (PHN)
This is a study to evaluate the safety and efficacy of 4% and 8% w/w TV 45070 ointment compared with placebo ointment applied topically and twice daily to the area of PHN pain for 4 weeks in patients with PHN
- Trial name
- (PHN) (NCT02365636)
- Testing
- TV-45070
- Where
- 77 sites in United States
- Volunteers
- 300 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Pudendal Neuralgia, Canal Syndrome
Therapeutic Effects Analysis of Pudendal Nerve Infiltrations After 3 Months, in Patients Suffering of Pudendal Neuralgia
Pudendal neuralgia is a recent identified pathology, extremely invalidating, related to chronic pelvic entrapment. Nowadays, pudendal neuralgia can be treated with: neuropathic pains treatment specific kinesitherapy Alcock's…
- Trial name
- INFILTHERA (NCT00851513)
- Testing
- Lidocaine, Depmedrol, physiological serum
- Where
- 9 sites in France
- Volunteers
- 202 people
- Sponsor
- Nantes University Hospital
Neuroma, Neuropathic Pain
Pain Outcomes After Digital Amputation Using Tulavi Allay™ Nerve Cap
In 2016, one in five individuals in the United States (US) experienced chronic pain, and approximately 40% of them suffered from neuropathic pain.
- Trial name
- NCT06915662
- Testing
- Tulavi allay Nerve Cap
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Massachusetts General Hospital
Peripheral Nerve Stimulation, Chronic Neuropathic Pain
Mechanisms of Stimulation for Pain Alleviation
This is a mechanistic randomized controlled trial of patients with chronic neuropathic pain (CNP) in the upper extremities, lower back, pelvis, and lower extremities, randomized to conventional medical management (CMM) or…
- Conditions
- Peripheral Nerve Stimulation, Chronic Neuropathic Pain, Chronic Neuropathic Pain (Below the Shoulders)
- Trial name
- M-SPA (NCT06741579)
- Testing
- Peripheral Nerve Stimulation, Conventional Care Regimen
- Where
- 2 sites in United States
- Volunteers
- 148 people
- Sponsor
- Stanford University
Pain
Efficacity of a Standardized Hypnotic Message During the Application of a Qutenza (Capsaicin) 8% Patch
QUTENZA® is a skin patch with a high concentration of capsaicin (8%) which is the component responsible for spicy peppers. QUTENZA® is indicated for the treatment of peripheral neuropathic pain in non-diabetic adults either alone…
- Trial name
- ENHYZA (NCT02822625)
- Testing
- QUTENZA®, hypnotic message, music therapy
- Where
- France
- Volunteers
- 69 people
- Sponsor
- Institut de Cancérologie de Lorraine
Neuropathic Pain, Complex Regional Pain Syndrome Type 1
Effectiveness of Ketamine Administered by Mesotherapy in Complex Regional Pain Syndrome Type 1 (CRPS1)
Complex Regional Pain Syndrome type 1 (CRPS1) is a disabling pain syndrome. Its definitive treatment has not been established and the results of current treatments are often unsatisfactory.
- Trial name
- MESO-SDRC (NCT04650074)
- Testing
- LIDOCAINE 20 mg, LIDOCAINE 20 mg + KETAMINE 20 mg, LIDOCAINE 20 mg + KETAMINE 40 mg
- Where
- France
- Volunteers
- 31 people
- Sponsor
- Hospices Civils de Lyon
Cervicobrachial Neuralgia, Cervical Discopathy
GRANVIA®-C Cervical Disc Prosthesis Multicenter European Pilot Study
This is a prospective clinical study to assess the performance of the prosthesis according to a composite success criterion. The clinical and functional results and the patient's quality of life up to 24 months of follow-up will…
- Trial name
- NCT01518582
- Testing
- Cervical arthroplasty surgery with Granvia-C
- Where
- 3 sites in Belgium, France
- Volunteers
- 70 people
- Sponsor
- Medicrea International
Herpes Zoster, Neuralgia
Study of NGX-4010 for the Treatment of Painful HIV-Associated Neuropathy (HIV-AN) or Postherpetic Neuralgia (PHN)
The purpose of the study is to evaluate the safety and efficacy of NGX-4010 administered at intervals of no less than 12 weeks over 1 year, based on the presence or return of pain, for the treatment of painful HIV-AN and PHN.
- Conditions
- Herpes Zoster, Neuralgia, Pain, HIV Infections
- Trial name
- NCT00233155
- Testing
- Capsaicin Dermal Patch
- Volunteers
- 100 people
- Sponsor
- NeurogesX
Painful Diabetic Neuropathy
Eslicarbazepine Acetate as Therapy in Diabetic Neuropathic Pain
The primary objective of this study is to assess the efficacy of Eslicarbazepine acetate (ESL) as therapy in subjects with Diabetic Neuropathic Pain (DNP) over a 15 week treatment phase.
- Trial name
- NCT01129960
- Testing
- Eslicarbazepine acetate (BIA 2-093)
- Where
- Portugal
- Volunteers
- 332 people
- Sponsor
- Bial - Portela C S.A.
Sciatica, Piriformis Muscle Syndrome
Ultrasonographic Evaluation of the Sciatic Nerve in Patients With Piriformis Syndrome
Piriformis syndrome (PS) is defined as a neuropathy of entrapment resulting from compression and irritation of the sciatic nerve at the level of the piriformis muscle (PM) at the pelvic outlet, causing sciatica radiating to the…
- Trial name
- Sciatica (NCT06783439)
- Testing
- Ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 19 people
- Sponsor
- Istanbul University - Cerrahpasa
Painful Diabetic Peripheral Neuropathy
Ricolinostat in Patients With Painful Diabetic Peripheral Neuropathy
This is a randomized, double-blind, 2-arm, parallel group study of up to 274 evaluable patients designed to evaluate the safety and efficacy of the histone deacetylase 6 (HDAC6) inhibitor ricolinostat for painful DPN.
- Trial name
- NCT03176472
- Testing
- ricolinostat
- Where
- 35 sites in United States
- Volunteers
- 282 people
- Sponsor
- Regenacy Pharmaceuticals LLC
Neuropathic Pain, Child, Only
Neuropathic Pain in Children: Multimodal Assessment and Diagnosis
Some children experience chronic pain that is related to damage or diseases that affect the nerves that send pain signals. This is known as neuropathic pain. This is not well understood and can be difficult to diagnose.
- Trial name
- NCT03312881
- Testing
- quantitative sensory testing, neuroimaging, Patient Reported Outcome Measures
- Where
- United Kingdom
- Volunteers
- 160 people
- Sponsor
- Institute of Child Health
Diabetic Peripheral Neuropathic Pain
Study of the Safety, Tolerability and Efficacy of V3381 in Patients With Diabetic Peripheral Neuropathic Pain
Randomised, double-blind, placebo-controlled, parallel group, multicentre study of oral doses of V3381, titrated to effect. A 2-week single-blind run-in period will be followed by a 13 week double-blind titration and maintenance…
- Trial name
- NCT00794430
- Testing
- V3381
- Where
- 31 sites in United States, Canada and 2 more
- Volunteers
- 161 people
- Sponsor
- Vernalis (R&D) Ltd