Clinical trials: Neuralgia Peripheral
Neuropathic Pain
A Study on the Safety and Efficacy of Nitric Oxide Gel in Subjects With Painful Diabetic Neuropathy
This is a randomized, double-blind, placebo-controlled, 2-period crossover, 12-week trial to be conducted in 50 subjects with painful diabetic neuropathy.
- Trial name
- NCT01633086
- Testing
- nitric oxide gel
- Where
- Taiwan
- Volunteers
- 24 people
- Sponsor
- China Medical University Hospital
Diabetic Peripheral Neuropathic Pain, Post-herpetic Neuralgia
DS-5565 Phase III Study for Renal Impairment in Japanese Subjects
Investigate the safety and efficacy of DS-5565 in Japanese subjects with Diabetic Peripheral Neuropathic Pain (DPNP) with renal impairment or Post-Herpetic Neuralgia (PHN) with renal impairment.
- Trial name
- NCT02607280
- Testing
- DS-5565
- Where
- Japan
- Volunteers
- 35 people
- Sponsor
- Daiichi Sankyo Co., Ltd.
Breast Cancer
"Electro Acupuncture in the Treatment and Management of Chemotherapy Induced Peripheral Neuropathy"
To evaluate the effectiveness of Electro acupuncture (EA) for treatment of persistent painful CIPN symptoms in patients with stages 1-3 breast cancer treated with docetaxel chemotherapy 6 months prior
- Trial name
- NCT02821442
- Testing
- Acupuncture
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Manitoba
Neuropathy, Painful, Chemotherapy-induced Peripheral Neuropathy
Lidocaine for Oxaliplatin-induced Neuropathy
Oxaliplatin-induced neuropathy is a major dose-limiting side effect in patients with colorectal cancer treated with the FOLFOX chemotherapy regimen.
- Conditions
- Neuropathy, Painful, Chemotherapy-induced Peripheral Neuropathy, Colorectal Cancer
- Trial name
- NCT03254394
- Testing
- Lidocaine Hydrochloride, FOLFOX regimen
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Washington University School of Medicine
Diabetic Peripheral Neuropathy, Diabetic Peripheral Neuropathic Pain
Exercise Induced Hypoalgesia Diabetes
The purpose of this research study is to learn whether different forms of exercise can reduce pain experienced by individuals with painful diabetic peripheral neuropathy.
- Trial name
- EIHDM (NCT05296642)
- Testing
- Moderate Cycling, Personalized Tourniquet System
- Where
- United States
- Sponsor
- University of Miami
Neuralgia, Perineal
Promoting Optimal Healing After Laceration Repair Study
The goal of this research is to investigate three different methods of perineal skin closure during second-degree perineal wound repair and determine which method is associated with the least amount of patient pain.
- Trial name
- PALS (NCT02055794)
- Testing
- Suturing of the perineal skin, Closing perineal skin with surgical glue, No suturing of the perineal skin
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Postherpetic Neuralgia ( PHN )
Electroacupuncture for PHN: Efficacy and Biomarker Evaluation in a Multicenter, Randomized, Sham-Controlled Trial Protocol
The investigators are conducting a clinical study with the following objectives: to evaluate the clinical efficacy of electroacupuncture combined with pregabalin in treating Postherpetic Neuralgia(PHN); to investigate the…
- Trial name
- NCT06990854
- Testing
- Electroacupuncture (Hans-100A, Nanjing Jisheng Medical Technology, China), Pharmacotherapy：① Pregabalin ( Lyrica™ ，Pfizer Inc. America) ② Methylcobalamin ( Mecobalamin tablets， Weicai (China) Pharmaceutical Co., Ltd， China）
- Where
- China
- Volunteers
- 207 people
- Sponsor
- Dexiong Han
Causalgia, Polyneuropathy
Efficacy of Etoricoxib on Peripheral Hyperalgesia
The purpose of the study is to determine the efficacy of etoricoxib on pain patients. The investigators assume that patients with neuropathic pain will have greater pain relief then patients on placebo.
- Conditions
- Causalgia, Polyneuropathy, Postherpetic Neuralgia, Peripheral Nerve Injury
- Trial name
- NCT01088256
- Testing
- Etoricoxib
- Where
- Germany
- Volunteers
- 9 people
- Sponsor
- Ruhr University of Bochum
Chemotherapy-induced Peripheral Neuropathy (CIPN), Acupuncture
Efficacy of Acupuncture on Chemotherapy-Induced Peripheral Neuropathy (CIPN)-TMANH
This three-armed, multicenter, randomized, parallel, sham-controlled clinical trial will conduct in three centers in Taiwan. The investigators will randomly assign 234 eligible patients into three groups, an acupuncture group…
- Trial name
- AcuCIPN (NCT07693335)
- Testing
- Acupuncture, Minimal acupuncture
- Where
- Taiwan
- Volunteers
- 28 people
- Sponsor
- Taiwan Municipal An-Nan Hospital-China Medical University
Diabetic Peripheral Neuropathic Pain
Effectiveness of Electroacupuncture in the Treatment of Diabetic Peripheral Neuropathy
Diabetic Peripheral Neuropathy (DPN) is one of the most common chronic complications of diabetes mellitus, which mainly manifests symmetric pain, numbness, ankylosis, or with abdominal distension, abnormal sweating, and…
- Trial name
- NCT06054087
- Testing
- Basal therapy+EA, Basal therapy
- Where
- China
- Volunteers
- 104 people
- Sponsor
- Zhejiang Chinese Medical University
Radius Fracture Distal, Surgery
Volar Locking Plate Versus External Fixation for Distal Radius Fracture - a Longterm Follow up
A 10-year follow up of a fusion of two earlier published randomized controlled trials. 203 patients with displaced distal radius fractures were randomized to surgery with a volar locking plate or external fixation.
- Conditions
- Radius Fracture Distal, Surgery, Surgery--Complications, Treatment Complication
- Trial name
- EXTEND (NCT05371938)
- Testing
- Volar locking plate, external fixation
- Where
- Sweden
- Volunteers
- 203 people
- Sponsor
- Olof Skoldenberg
Pain, Chronic Pain
Evaluation of Effectiveness and Tolerability of Tapentadol Hydrochloride in Subjects With Severe Chronic Low Back Pain Taking WHO Step III Analgesics But Showing a Lack of Tolerability
The main objective of the study is to evaluate the effectiveness, tolerability, and safety of tapentadol hydrochloride prolonged release in subjects suffering from severe chronic low back pain (LBP) who are taking WHO Step III…
- Conditions
- Pain, Chronic Pain, Low Back Pain, Neuropathic Pain
- Trial name
- NCT00986258
- Testing
- Tapentadol Prolonged Release
- Where
- 27 sites in Belgium, Czechia and 6 more
- Volunteers
- 136 people
- Sponsor
- Grünenthal GmbH
Neuropathic Pain, Orofacial Pain
Pain and Perceptual Distortion of Face
Post-traumatic trigeminal neuropathic pain (PTNP) is "a unilateral or bilateral facial or oral pain following and caused by trauma to the trigeminal nerve(s), with other symptoms and/or clinical signs of trigeminal nerve…
- Trial name
- NCT06577649
- Testing
- Active repetitive transcranial magnetic stimulation (rTMS)
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- University of Aarhus
Complex Regional Pain Syndromes
Ketamine and Midazolam Infusions for CRPS: Feasibility Study
This study will assess the feasibility of administering ketamine plus midazolam or midazolam alone, when infused over 5 days in an outpatient setting, to adults with complex regional pain syndrome (CRPS).
- Trial name
- NCT05945147
- Testing
- Ketamine, Midazolam, Normal Saline
- Where
- United States
- Sponsor
- Stanford University
Neuropathic Pain, Spinal Cord Injury
Ultramicronized PEA (Normast) in Spinal Cord Injury Neuropathic Pain
Randomized, double-blinded, placebo-controlled, parallel group study of ultramicronized PEA (Normast)600 mg x 2 daily or corresponding placebo with a week of baseline period followed by 1 x 12 weeks treatment period.
- Trial name
- NCT01851499
- Testing
- Ultramicronized PEA (Normast)
- Where
- 2 sites in Denmark
- Volunteers
- 73 people
- Sponsor
- Danish Pain Research Center
Low Back Pain, Disc Disease
Fibrin for Chronic Multi-level Discogenic Low Back Pain
Intra-annular injections of non-autologous fibrin for moderate to severe chronic low back pain (LBP).
- Conditions
- Low Back Pain, Disc Disease, Disc Degeneration, Radiculopathy
- Trial name
- NCT04621799
- Testing
- Fibrin sealant
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Pauza, Kevin, MD
Piriformis Syndrome
Foam Rolling and Dynamic Stretching in Piriformis Syndrome
To compare the combined effects of foam rolling and dynamic stretching in patients with piriformis syndrome. 1. Warm-Up (2-3 minutes) Objective: Increase blood flow and prepare muscles for stretching.
- Trial name
- NCT07278193
- Testing
- Group A (Foam Rolling), Group B (Foam rolling and Dynamic Stretching)
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- University of Lahore
Radiculopathy, Sciatica
Clinical Trial to Evaluate the Safety and Analgesic Efficacy of VVZ-149 in Lumbar Radiculopathy (Sciatica)
Double-blind, crossover, randomized, 3x3 Latin square, placebo-controlled study of single intravenous dose administration of VVZ-149. To demonstrate assay sensitivity, lidocaine will be administered as a positive control.
- Trial name
- LMR (NCT02644421)
- Testing
- VVZ-149, Lidocaine
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Brigham and Women's Hospital
Neuropathic Pain Management, Diabetic Neuropathies, Painful
Beneficial Effects of Supplementation With CRONILIEF™ (Palmitoylethanolamide Phospholipids) in Diabetic Subjects With Neuropathic Pain.
This study aims to evaluate the potential benefit of an oral nutritional supplement based on CRONILIEF™ (Palmitoylethanolamide Phospholipids) in diabetic subjects with neuropathic pain, compared to a placebo.
- Conditions
- Neuropathic Pain Management, Diabetic Neuropathies, Painful, Palmitoylethanolamide
- Trial name
- NCT07377409
- Testing
- Cronilief™ (300 mg)
- Volunteers
- 70 people
- Sponsor
- Azienda di Servizi alla Persona di Pavia
Coccyx Disorder, Neuropathic Pain
Study Evaluating the Analgesic Efficacy of Capsaicin 8% Patches in Chronic Coccygodynia.
The primary objective is to demonstrate the analgesic effect at day 60 of 8% capsaicin patch (Qutenza) for the treatment of patients with coccygodyinia.
- Conditions
- Coccyx Disorder, Neuropathic Pain, Coccygodynia
- Trial name
- CAPSACOX (NCT06023706)
- Testing
- Capsaicin 179 Mg Cutaneous Patch, Capsaicin low concentration patch (capsaicin 0,04%, 3,2 mg/cm2)
- Where
- 6 sites in France
- Volunteers
- 188 people
- Sponsor
- Nantes University Hospital
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