Clinical trials: Neurally Adjusted Ventilatory Assist
Chronic Obstructive Pulmonary Disease
Neurally Adjusted Ventilatory Assist and Synchrony in Patients With Chronic Obstructive Pulmonary Disease (COPD)
NAVA used the electrical activity of the diaphragm (EAdi) to initiate and deliver in proportion of an inspiratory assistance. During inspiration, EAdi signal occurred earlier than airflow or pressure variations in the airway.
- Trial name
- NAVASYNC (NCT01042080)
- Testing
- NAVA, Expiratory trigger (ET)
- Where
- 2 sites in France
- Volunteers
- 16 people
- Sponsor
- Hôpital Européen Marseille
Respiratory Failure
Non-invasive Neurally Adjusted Ventilatory Assist
Neurally adjusted ventilatory assist (NAVA) is a new concept of mechanical ventilation. NAVA delivers assistance to spontaneous breathing based on the detection of the electrical activity of the diaphragm.
- Trial name
- NCT01280383
- Testing
- non-invasive neurally adjusted ventilatory assist
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Acute Respiratory Failure
Adjusted Ventilatory Assist (NAVA-NIV) in Infants: Short-term Physiological Study
Neurally Adjusted Ventilatory Assist (NAVA) is a new form of partial support wherein the machine applies positive pressure throughout inspiration in proportion to the electrical activity of the diaphragm (EAdi), as assessed by…
- Trial name
- NCT02043990
- Testing
- Noninvasive NAVA ventilation
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Mechanical Ventilation
Mechanical Ventilation Controlled by the Electrical Activity of the Patient's Diaphragm - Effects of Changes in Ventilator Parameters on Breathing Pattern
Neurally adjusted ventilatory assist (NAVA) is a new concept of mechanical ventilation. NAVA delivers assist to spontaneous breathing based on the detection of the electrical activity of the diaphragm.
- Trial name
- NCT00529347
- Testing
- neurally adjusted ventilatory assist (NAVA)
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Acute Lung Injury, Mechanical Ventilation
NAV-ALI: Neurally Adjusted Ventilatory Assist in Patients Recovering Spontaneous Breathing After Acute Lung Injury
Evaluation of a new ventilatory mode Neurally Adjusted Ventilatory Assist "NAVA" in patients who recover spontaneous breathing after acute lung injury.
- Trial name
- NCT00963066
- Testing
- PSV - pressure suppot ventilation, NAVA - Neurally Adjusted Ventilatory Assist, NAVA - EMG
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Caen
Newborn Morbidity
Effect of Changing Levels of Neurally Adjusted Ventilatory Assist (NAVA) in Newborns
To examine the effect of changing levels of support during NAVA-ventilation ("NAVA-level") on electrical diaphragm activity of the newborn on invasive or non-invasive NAVA ventilation.
- Trial name
- NCT03780842
- Testing
- NAVA level
- Where
- Belgium
- Volunteers
- 21 people
- Sponsor
- Julie Lefevere
Congenital Diaphragmatic Hernia
Neurally Adjusted Ventilatory Assist for Neonates With Congenital Diaphragmatic Hernias
Congenital Diaphragmatic Hernias (CDH) are typically repaired surgically in the first few days of a neonate's life. Following surgical repair, infants usually require ventilatory support to ensure adequate oxygenation.
- Trial name
- NAN-C (NCT05839340)
- Testing
- Neurally Adjusted Ventilatory Assist, Assist Control Ventilation
- Where
- 2 sites in United Kingdom
- Volunteers
- 18 people
- Sponsor
- King's College Hospital NHS Trust
Obstructive Lung Diseases
Can NAVA Mode Reduce Mechanical Ventilation Day in Patients With COPD ?
Background： Neurally Adjusted Ventilatory Assist (NAVA) mode is a new mode of ventilator, using electronic potential of diaphragm to adjust tidal volume.
- Trial name
- NCT05595733
- Testing
- Ventilator mode
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Fu Jen Catholic University Hospital
Respiratory Failure
Conventional vs Neurally Adjusted Ventilatory Assist in Difficult Weaning From Mechanical Ventilation
The NAVA, by its more physiological aspect and a better adaptation of the patient to the ventilator with a decrease of asynchronies patients-ventilators, could decrease the duration of weaning and so decrease the duration of…
- Trial name
- SENA (NCT02382861)
- Testing
- Neurally adjusted ventilatory assist, Noninvasive pressure support ventilation
- Where
- France
- Volunteers
- 47 people
- Sponsor
- University Hospital, Bordeaux
Acute Respiratory Failure
Study Comparing Two Ventilation Modes NAVA (Neurally Adjusted Ventilatory Assist) Mode and Spontaneous Breathing With Inspiratory Pressure Support (IPS) Mode in Consecutive Patients Hospitalized for Acute Respiratory Failure Requiring Mechanical Ventilation With Endotracheal Tube.
This is a multicenter, prospective, randomized, open-label study which compared two ventilation modes: spontaneous NAVA mode and spontaneous breathing with IPS mode (the latter is considered as the reference ventilatory mode) in…
- Trial name
- NCT02018666
- Testing
- NAVA endotracheal tube
- Where
- 11 sites in France
- Volunteers
- 129 people
- Sponsor
- Clinact
Sleep, Cerebral Oxygenation
Respiratory Support and Brain Health in Preterm Infants
Premature babies often require breathing support during their neonatal intensive care unit stay. This is because their lungs are not fully developed to perform the work of breathing on their own.
- Trial name
- NCT05589831
- Testing
- Non-invasive Neurally Adjusted Ventilatory Assist
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Mount Sinai Hospital, Canada
Evaluation of Preterm NAVA Catheter Placement
Positioning of EDI Catheter In Premature Infants
Nasogastric (NG) and orogastric (OG) feeding tubes have a high incidence of malpositioning, occurring in up to 59% of preterm infants (Lopes 2019).
- Trial name
- PIPI (NCT05107713)
- Where
- Canada
- Volunteers
- 65 people
- Sponsor
- Unity Health Toronto
Respiration
Comparison of Pressure-, Flow- and Neurally Adjusted Ventilatory Assistance (NAVA)-Triggering in Pediatric and Neonatal Ventilatory Care
The purpose of this study is to study whether neurally adjusted ventilatory assist (NAVA) provides advantages over current methods in detecting patients own breathing efforts in pediatric and neonatal ventilatory care.
- Trial name
- NCT00893087
- Testing
- Triggering mode of the ventilator, Triggering method of the ventilator
- Where
- Finland
- Volunteers
- 18 people
- Sponsor
- University of Oulu
Respiratory Failure
Impact of NAVA (Neurally Adjusted Ventilatory Assist) on Ventilatory Demand During Pediatric Non-Invasive Ventilation
Mechanical ventilation permits to support the work of breathing in case of respiratory failure, but therapy also has many side effects.
- Trial name
- NAVANI (NCT02163382)
- Testing
- Neurovent Monitor XIII
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- St. Justine's Hospital
Non Invasive Ventilation, Patient Ventilator Interaction
Neurally Adjusted Ventilatory Assist for Non Invasive Ventilation and Patient-ventilator Interaction
The present study aims to compare various parameters reflecting patient-ventilator synchrony during standard pressure support (PS) and Neurally Adjusted Ventilatory assist (NAVA) in a group of patients receiving non invasive…
- Trial name
- NCT01074866
- Testing
- Neurally Adjusted Ventilatory Assist
- Where
- 4 sites in Belgium, Switzerland
- Volunteers
- 13 people
- Sponsor
- University Hospital, Geneva
Heart Defects, Congenital, Surgery
Feasibility Study Over the NAVA Mode in Noninvasive Ventilation After Cardiac Surgery in Infants.
Neonates who underwent cardiac surgery with cardiopulmonary bypass almost always require non-invasive respiratory support (NIV) in relay to conventional ventilation.
- Trial name
- NIVNAVA (NCT01570933)
- Testing
- NivNava, Cpap
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Ventilator Lung
Neurally Adjusted Ventilatory Assist (NAVA) vs Pressure Support Ventilation After Cardiac Surgery
The study compares two different ventilation modes, Pressure support ventilation vs. Neuronally Adjusted Ventilatory Assist, in postcardiac surgery patients. Of special interest is shunt and alveolar deadspace and ventral vs.
- Trial name
- NCT03217305
- Testing
- NAVA
- Where
- Sweden
- Volunteers
- 12 people
- Sponsor
- Sahlgrenska University Hospital
Respiratory Failure
Regional Distribution Differences Between Neurally Adjusted Ventilatory Assist and Pressure Support Ventilation
Neurally adjusted ventilatory assist (NAVA) is an FDA approved mode of mechanical ventilation. This mode of ventilation is currently in routine use in adult, pediatric and neonatal intensive care units.
- Trial name
- NCT01504373
- Testing
- Neurally Adjusted Ventilatory Assist (NAVA)
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Boston Children's Hospital
Respiratory Distress Syndrome, Newborn, Bronchopulmonary Dysplasia
Work of Breathing During Non-invasive Ventilation in Premature Neonates
Background: Non-invasive forms of respiratory support have been developed to manage respiratory distress and failure in premature newborns without exposing them to the risks associated with invasive mechanical ventilation.
- Trial name
- NCT02788110
- Testing
- Noninvasive neurally adjusted ventilatory assist (NIV NAVA), Nasal intermittent positive pressure ventilation (NIPPV)
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Arkansas Children's Hospital Research Institute
Diaphragm Electrical Activity, Neurally Adjusted Ventilatory Assist
Does Diaphragm Electrical Activity Monitoring Predict Extubation Success in Children?
This study aimed to record diaphragm electrical activity (Edi) during the preextubation (weaning) and postextubation periods and to analyze whether Edi monitoring could predict extubation success.
- Conditions
- Diaphragm Electrical Activity, Neurally Adjusted Ventilatory Assist, Pediatrics
- Trial name
- NCT06163183
- Testing
- Edi catheter
- Volunteers
- 25 people
- Sponsor
- Mersin University