Clinical trials: Neurobehavioral Manifestation
Delirium
Nu-DESC DK: The Danish Version of the Nursing Delirium Screening Scale
Delirium is one of the most common complications among elderly hospitalized patients, postoperative patients and patients on intensive care units. The reported prevalence is between 11 and 80 %.
- Trial name
- Nu-DESC DK (NCT02628925)
- Testing
- Nu-DESC DK
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Naestved Hospital
Vasovagal Syncope (VVS), Presyncope
A Warning Red Flag Classification System to Predict Risk of Vasovagal Event During Office Hysteroscopy
The goal of this pilot cross sectional study is to identify participants at risk of vasovagal reaction/syncope(VVR/VVS) during office hysteroscopy.
- Trial name
- FLAG-VS (NCT07030218)
- Testing
- Office hysteroscopy
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tanvir Hospital
Word Finding Difficulty, Communication Disorders
Intervention for Fluency Difficulty
The focus of the study is to identify children with word-finding difficulty and other speech and communication difficulties such as stuttering, a procedure referred to as screening.
- Trial name
- FIST (NCT04217460)
- Testing
- Intervention for fluency difficulty
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University College, London
Pain, Inflammatory, Pain Management
Reduced-pressure Pneumoperitoneum and Intraperitoneal Saline Washout to Alleviate Pain Following vNOTES Hysterectomy
vNOTES, initially employed for cholecystectomy, appendectomy, and nephrectomy, made its debut in the field of gynecologic surgery in 2012.
- Trial name
- Vnotes (NCT06944015)
- Testing
- normal saline
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Erzincan Military Hospital
Dementia, Caregiver Burnout
WeCareAdvisor Study for Caregivers of People Living With Dementia
The WeCareAdvisor is an online tool to help caregivers manage behavioral and psychological symptoms of people living with dementia.
- Conditions
- Dementia, Caregiver Burnout, Caregiver Stress Syndrome, Alzheimer Disease
- Trial name
- NCT05012410
- Testing
- Immediate treatment group with High-Intensity Prompts, Immediate treatment group with Low-Intensity Prompts, Waitlist Control after three months with High-Intensity Prompts
- Where
- United States
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- Drexel University
Stuttering, Childhood
Speech Signals in Stuttering
The purpose of this research study is to understand how speech and language are processed in the brain. This study will provide information that may help with the understanding how speech and language are processed in children…
- Trial name
- NCT05668923
- Testing
- Speech sound stimulation
- Where
- 2 sites in United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Language Disorder, Healthy
Language Stimuli Screening in Children
This study will determine baseline language skills in children 4 to 8 years old. The data will be used to design studies using functional magnetic resonance imaging (fMRI) to identify what areas of the brain in children are…
- Trial name
- NCT00016796
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Dexmedetomidine, Postoperative Delirium
Different Administration Routes of Dexmedetomidine on Postoperative Delirium
Intravenous dexmedetomidine has been reported to decrease the occurrence of postoperative delirium (POD) in elderly patients. Nevertheless, some previous studies have indicated that intratracheal dexmedetomidine and intranasal…
- Conditions
- Dexmedetomidine, Postoperative Delirium, General Anesthesia
- Trial name
- NCT05952050
- Testing
- Dexmedetomidine
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Boston Intelligent Medical Research Center, Shenzhen United Scheme Technology Co., Ltd.
Schizophrenia, Schizoaffective Disorder
Quantifying Abnormalities in Cortical Activation Associated With Auditory Hallucinations Using Functional Magnetic Resonance Imaging
The goal of the project is to characterize abnormalities in brain structure and function related to schizophrenia. The investigators will use advanced magnetic resonance imaging (MRI) techniques to measure the degree and…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Hallucinations
- Trial name
- NCT00288340
- Testing
- functional magnetic resonance imaging
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Apathy
Multidimensional Apathy in Psychiatric Pathologies.
Apathy is defined by quantitative decrease in goal-directed activity in comparison to the person's previous level of functioning.
- Trial name
- AmSeD (NCT04757220)
- Testing
- Cognitive tasks with EEG recording
- Where
- France
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Cerebral Palsy, Perceptual Disorders
Motor and Cognitive Functions in Acquired and Developmental Brain Damaged Patients
Neurological pathologies cause important and permanent disabilities in every day life. These pathologies can follow stoke, affecting two people per one thousand each year or cerebral palsy, affecting two births per one thousand…
- Conditions
- Cerebral Palsy, Perceptual Disorders, Hemiparesis
- Trial name
- NCT02543424
- Testing
- Motor, cognitive and neuropsychological assessment
- Where
- 2 sites in Belgium
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Memory Impairment
Examining the Effect of a Simple Memory Tool
Objective: There have been a wide variety of interventions to assist with cognition and memory of older adults; however, it is often unclear if the interventions have an impact on daily life memory performance and goal…
- Trial name
- NCT03244111
- Testing
- simple memory tool
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Delirium
Clinical Investigation of an Eye-Tracking Device as a Predictor of Delirium in the Recovery Room After Surgery With General Anesthesia
Neurotrack™ is an FDA-approved device for measuring and tracking cognitive decline, as may occur with age-related cognitive decline and Alzheimer's disease.
- Trial name
- NCT05579093
- Testing
- Cognitive test + Pupillary measure
- Where
- United States
- Volunteers
- 325 people, healthy volunteers welcome
- Sponsor
- Columbia University
Developmental Disability, Intellectual Disability
Online Learning Module to Advance Research Related to People With Disabilities
This study will measure the effects of a brief one-time eLearning intervention on researcher Knowledge, Attitudes, and Perceptions (KAP) of including people with disabilities (PWDs) in biomedical \& behavioral research.
- Conditions
- Developmental Disability, Intellectual Disability, Disability
- Trial name
- D2/R3 (NCT07220837)
- Testing
- eLearning module, Control
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Down Syndrome
Parent Supported Weight Reduction in Down Syndrome
The purpose of this study is to determine whether a nutrition and physical activity education program for families of overweight or obese adolescents with Down syndrome is more effective when behavioral lifestyle change…
- Trial name
- NCT01256112
- Testing
- Parent Supported Behavioral Intervention, Nutrition/Activity Education (NAE)
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Developmental Dyslexia
Prediction and Intervention in Developmental Dyslexia
The long-term goal of this study is to improve prediction of poor reading outcome at preschool age by using a combination of behavioural and neuroimaging measures and to evaluate a specific computerized training program to…
- Trial name
- LEXI (NCT02217696)
- Testing
- Computerized reading training
- Where
- Switzerland
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Amputation
AMI Construction in Lower Extremity Residual Limbs
This study will involve the development of a novel approach to lower extremity residual limb surgical revision that offers the promise of augmenting volitional motor control, restore proprioception and reverse atrophy
- Trial name
- NCT04063592
- Testing
- Residual limb revision
- Where
- 3 sites in United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Analgesia, Obstetrical, Postpartum Hemorrhage
Prospective Effect of Intravenous Ketorolac on Opioid Use, EBL and Complications Following Cesarean Delivery
In this randomized, double-blind control trial to evaluate the effect of ketorolac given at the time of cord clamp has on estimated blood loss and postcesarean pain control.
- Conditions
- Analgesia, Obstetrical, Postpartum Hemorrhage, Opioid Use, Nonsteroidals (NSAIDs)Toxicity
- Trial name
- NCT02509312
- Testing
- Ketorolac
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Parkinson Disease, Ataxia
Rhythmic Entrainment in Bilingual Speakers With Dysarthria
The objectives of this study are to determine i) the effect of rhythmic entrainment of speech with hand gestures and auditory rhythmic cues on intelligibility and speech naturalness in Spanish-accented speakers of English in two…
- Trial name
- NCT03645265
- Testing
- Auditory, Gestures
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Herbert H. Lehman College, City University of New York
Pain, Pain Management
Pain in Aging Former Athletes, Master's Athletes, and Nonathletes
The goal of this clinical trial is to determine how male and female former athletes experience pain and respond to moderate-intensity exercise (strength versus aerobic) compared with both current master's athletes and…
- Conditions
- Pain, Pain Management, Athlete, Exercise Training
- Trial name
- PAIN (NCT07502742)
- Testing
- Moderate-Intensity Strength Exercise Intervention, Moderate-Intensity Aerobic Exercise Intervention
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Marquette University
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