Clinical trials: Neurocognitive Deficit
ADHD
Effects of Noise Cancelling Headphones on Neurocognitive and Academic Outcomes in ADHD
The purpose of this study is to evaluate performance on the Attention Deficit Hyperactivity Disorder ( ADHD) Battery of the Cambridge Automated Neuropsychological Test Battery (CANTAB), including spatial working memory…
- Trial name
- NCT03216512
- Testing
- Use of Noise Cancelling Headphones
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Duke University
Cognitive Change, Cognitive Decline
Normative Database and Test-Retest Reliability for BrainCheck Assessments
The purpose of this study is to collect normative test values and demographic information for normative and referential data for a rapid, portable, computerized neurocognitive testing device from healthy adults 50 and older.
- Conditions
- Cognitive Change, Cognitive Decline, Cognitive Deterioration, Neurocognitive Deficit
- Trial name
- NDTR (NCT05497427)
- Testing
- BrainCheck Assessment
- Where
- 5 sites in United States
- Volunteers
- 1,300 people, healthy volunteers welcome
- Sponsor
- BrainCheck, Inc.
Healthy Subjects
Nicotinic Modulation of Schizophrenia-like Information Processing Deficits in Healthy Subjects
This study examines the interactive effects of ketamine and nicotine.
- Trial name
- NCT00690170
- Testing
- Ketamine, Nicotine, Ketamine and Nicotine
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Yale University
Attention Deficit Hyperactivity Disorder
Neurocognitive Exercise Program for Children With Attention Deficit and Hyperactivity Disorder
The effects of Neurocognitive Exercise Program (NEP) on ADHD symptoms and executive functions in children with Attention Deficit and Hyperactivity Disorder (ADHD) will be investigated using The Conners parent rating scale-revised…
- Trial name
- NCT04707040
- Testing
- Neurocognitive Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
Anesthesia
Anesthesia Related Neurocognitive Deficits in Children
The infantile brain has to pass essential, mayor steps in the first 36 months of life. During that period of development it is particularly vulnerable to toxic, exogenic influences.
- Trial name
- ANFOLKI-36 (NCT03034889)
- Where
- Germany
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Heart Defects, Congenital, Critical Illness
Leuven Growing Into Deficit Follow-up Study
The key objective of the Leuven growing-into-deficit (GID) follow-up-study is to test the hypothesis that children with a congenital heart disease (CHD) show more neurocognitive impairment at the second follow-up at 7 years old…
- Conditions
- Heart Defects, Congenital, Critical Illness, Mental Processes, Child
- Trial name
- Leuven-GID (NCT01632813)
- Where
- Belgium
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Epilepsy, Cognitive Deficits
Methylphenidate Treatment of Attention Deficits in Epilepsy
Methylphenidate (MPH) has long been used to improve attention and cognitive difficulties associated with ADHD, including in children with ADHD and epilepsy (Torres et al., 2008).
- Conditions
- Epilepsy, Cognitive Deficits, Attention Deficits
- Trial name
- NCT02178995
- Testing
- Methylphenidate
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Kimford Jay Meador
Alzheimer Disease
Targeting zDHHC Enzymes to Counteract Alzheimer's Disease
Alzheimer's disease (AD) is a growing problem for aging populations worldwide and represents one of the most demanding challenges for biomedical and pharmacological research.
- Trial name
- zTARGETAD (NCT06677632)
- Testing
- Palmitoylation Enzyme Expression Profiling Study
- Where
- Italy
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Traumatic Brain Injuries, Neurobehavioral Manifestations
Self-defining Memories in Patients With a TBI
The study will be conducted over 18 months. The main objective of this study is to explore the relationships between autobiographical memory and specific cognitive measures, as well as emotional and behavioural measures in…
- Conditions
- Traumatic Brain Injuries, Neurobehavioral Manifestations, Cognition Disorders, Memory Deficits
- Trial name
- IDENTITY (NCT02680210)
- Testing
- Questionnaires and cognitive measures
- Where
- France
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Centre d'Investigation Clinique et Technologique 805
Mild Cognitive Impairment, Cerebral Blood Flow
A Study of Low-level Light Therapy Using Photo-activated Modulation Ameliorates Cognitive Deficits
The primary objective of this study is to confirm and compare the effect of methods of Low-level light therapy (LED-T) in the mild cognitive impairment.
- Conditions
- Mild Cognitive Impairment, Cerebral Blood Flow, Low-level Light Therapy, Brain Activity
- Trial name
- NCT03192670
- Testing
- Low-level light therapy device
- Where
- 2 sites in South Korea
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Yong-il Shin, MD
Attention-deficit/Hyperactivity Disorder
Attention-deficit/Hyperactivity Disorder Translational Center for Identifying Biomarkers
The purpose of this study was to identify genetic, brain morphologic, and environmental biomarkers that contribute to the pathophysiology of attention-deficit/hyperactivity disorder (ADHD).
- Trial name
- NCT02623114
- Testing
- methylphenidate, atomoxetine
- Where
- South Korea
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Seoul National University Childrens Hospital
Postoperative Cognitive Deficit (POCD), Neurocognitive Disorders
International Observational Study on Perioperative Cognitive Trajectories (POCD Census International/PCI)
The purpose of this international, multi-centre observational study is to describe perioperative cognitive changes (pre-existing neurocognitive disorder [NCD], postoperative delirium [POD] and Postoperative Cognitive Dysfunction…
- Trial name
- NCT03540433
- Where
- 3 sites in Germany
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Post Traumatic Stress Disorder, Cognitive Deficit
Investigating the Use of Goal Management Therapy in Improving Cognitive Functioning in Public Safety Personnel With PTSD
This study examines the efficacy of Goal Management Therapy (GMT) - a well-established cognitive remediation strategy aimed at improving goal-directed behaviors that are dependent on basic cognitive processes and on executive…
- Trial name
- NCT04251624
- Testing
- Goal Management Therapy, Psychosocial Education
- Where
- Canada
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Homewood Research Institute
Cognitive Decline, Cognitive Deficit
Validation Study SCOBES-AR
Purpose of the study The purpose of this study is to evaluate five tests to see if they are suitable for the early detection of cognitive impairment in people over the age of 60.
- Conditions
- Cognitive Decline, Cognitive Deficit, Cognitive Impairment
- Trial name
- NCT04204239
- Where
- Austria
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- FH Joanneum Gesellschaft mbH
Postoperative Cognitive Dysfunction, Mild Cognitive Impairment
Cognitive Changes After Major Joint Replacement
Patients assume that cognitive performance rapidly returns to baseline after anesthesia and surgery. Several studies have shown that one week after major non-cardiac surgery about 27% of patients have postoperative cognitive…
- Conditions
- Postoperative Cognitive Dysfunction, Mild Cognitive Impairment, Delirium, Cognitive Deficit
- Trial name
- Cognigram (NCT02964221)
- Testing
- Cognitive Testing
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Dr. Stephen Choi
Early Memory Loss, Mild Cognitive Impairment
NAC-003 P.L.U.S. Program (Progress Through Learning Understanding & Support)
This study will be an observational study in which patients who have been prescribed CerefolinNAC® are invited to participate in surveys regarding their experiences with CerefolinNAC®.
- Conditions
- Early Memory Loss, Mild Cognitive Impairment, Alzheimer's Disease, Vascular Dementia
- Trial name
- NCT01370954
- Testing
- CerefolinNAC®
- Where
- United States
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Pamlab, Inc.
Schizophrenia, Psychosis
Cognitive Remediation in Schizophrenia
The aim of this project is to undertake a randomized placebo controlled trial of cognitive remediation therapy (CRT) that focuses on working memory training in a sample of community based patients with chronic schizophrenia or…
- Trial name
- NCT01903707
- Testing
- Cognitive Remediation Therapy
- Where
- Ireland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Dublin, Trinity College
Mild Cognitive Impairment, Behavioral Symptoms
The Moderating Roles of Social Support, Coping Resources and Personality and Mediating Role of Self-esteem on the Impact of Cognitive Deficit on Neuropsychiatric Symptoms Among Persons With Mild Cognitive Impairment: A Mixed-method Sequential Explanatory Design
This is a sequential mixed study to test the hypothesized models with seven hypotheses of the relationship between cognitive deficit (subject and objective) and neuropsychiatric symptoms (NPS) among persons with mild cognitive…
- Trial name
- NCT04085107
- Testing
- Face-to-face interviews
- Where
- Hong Kong
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
ADD, ADHD
Neurocognitive and Neurobiological Improvement in ADHD Children With High Protein Diet
Multicenter, Prospective, randomized, comparative and controlled study about the beneficial effects in behavior and brain connectivity of different dietary patterns in 100 children with ADHD between 7 and 12 years, followed up…
- Trial name
- BrainProtein (NCT02614599)
- Testing
- BP22042013, Low carbohydrate diet
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Spanish Foundation for Neurometrics Development
Healthy, CVA
Development of Automated Analysis to Electroencephelogram (EEG) Data in Patients Treated at the Sagol Hyperbaric Medicine and Research Center at the Years 2017-2019.
DELPhI software developed for the analysis of EEG recordings in response to magnetic stimulation in relation to clinical data.
- Conditions
- Healthy, CVA, Hemorrhage, TBI (Traumatic Brain Injury)
- Trial name
- NCT04095377
- Testing
- No intervention, this is a retrospective study.
- Where
- Israel
- Volunteers
- 875 people, healthy volunteers welcome
- Sponsor
- QuantalX Neuroscience