Clinical trials: Neurodevelopmental Conditions
Learning Disturbance
Complex Motor Learning With Motor Imaginary
Subjects participate in a motor learning training with a special bicycle. The experimental group proceed with 15 minutes of physical training with the bicycle and 15 minutes of rest where they use motor imaginary.
- Trial name
- NCT02999516
- Testing
- Motor imaginary, Non Motor imaginary, tDCS
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centro Universitario La Salle
Physical Activity, Motor Skills Development
Feasibility and Acceptability of a Co-produced Intervention to Improve Physical Activity and Motor Competence Amongst Children With Intellectual Disabilities and/or Autism Spectrum Disorder: Movement Matters
The goal of this observational study is to find out whether an intervention designed to improve physical activity levels and movement skills is practical and acceptable for children aged 7-11 years with intellectual disabilities…
- Trial name
- MM (NCT07456514)
- Testing
- Movement Matters
- Where
- United Kingdom
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Liverpool John Moores University
Nutritional Deficiencies, Developmental Delay
Project Grow Smart: Intervention Trial of Multiple Micronutrients and Early Learning Among Infants in India
Project Grow Smart evaluates the impact fortification with multiple micronutrient powders (MNP) vs. placebo (one vitamin) on child development (primary outcome) and on micronutrient status, growth, and morbidity (secondary…
- Trial name
- GrowSmart (NCT01660958)
- Testing
- MNP, Early Learning
- Where
- India
- Volunteers
- 834 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Developmental Articulation Disorder, Stuttering
Study of Brain Activity During Speech Production and Speech Perception
The purpose of this study is to gain a better understanding of the brain's activity and organization in the development of speech disorders.
- Trial name
- NCT00004991
- Where
- United States
- Volunteers
- 411 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Autism, Developmental Delay
Developmental Delay in Children Exposed During Pregnancy to Either Lamotrigine,Sodium Valproate, or Carbamazepine
This study is investigating the neurodevelopmental effects of prenatal exposure to lamotrigine (LTG), sodium valproate (VPA), or carbamazepine (CBZ) monotherapies. The hypotheses to be tested include: 1.
- Conditions
- Autism, Developmental Delay, Birth Defects
- Trial name
- NCT01097720
- Where
- United States
- Volunteers
- 298 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Refractive Error, Visual Impairment
The Baltimore Reading and Eye Disease Study
The Baltimore Reading and Eye Disease Study (BREDS) is a two year study to determine the prevalence of vision problems in an early school age population with reading difficulty.
- Conditions
- Refractive Error, Visual Impairment, Convergence Insufficiency, Reading Disabilities
- Trial name
- BREDS (NCT02607384)
- Testing
- Eyeglass wearing, Orthoptic exercises, Specialist referral
- Volunteers
- 328 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Autism Spectrum Disorder
Tool for Evaluating the Effectiveness of the DENVER Protocol
Early remediation of the communicative and social difficulties of children with autism spectrum disorders (ASD) is central. However, from the age of 6-8 months, children with ASD show a lack of attention to social stimuli such as…
- Trial name
- FACECOM (NCT06253793)
- Where
- 3 sites in France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Physical Activity, Health Promotion
Move it, Move ID! Promotion of Physical Activity in Adolescents With Intellectual Disability
The aim of this study is to develop and implement an mHealth intervention focusing on the promotion of physical activity in adolescents with intellectual disability.
- Conditions
- Physical Activity, Health Promotion, Adolescents, Intellectual Disability
- Trial name
- NCT05149443
- Testing
- theory-based mHealth-intervention (app)
- Where
- Belgium
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University Ghent
Dyslexia
Reading and Stuttering
Dyslexia is a common neurodevelopmental condition, which manifests itself in the form of reading difficulties and occurs in 7-10% of the population (Peterson \& Pennington, 2012).
- Trial name
- NCT06836115
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Wafaa Helmy Abdelhakeem
Intellectual Disability, Developmental Delay
Establishing the Clinical Utility of First StepDx PLUS and NextStepDx PLUS Study
The study uses a randomized controlled study design of pediatric neurologists and developmental pediatricians and front-line (primary care) pediatricians to determine if use of FirstStepDx PLUS and Next StepDx PLUS are associated…
- Trial name
- NCT02414438
- Testing
- FirstStepDX PLUS and NextStepDX PLUS Webinar, FirstStepDX PLUS and NextStepDX PLUS Test Results
- Where
- United States
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Qure Healthcare, LLC
Depression - Major Depressive Disorder, Bipolar
Behavioural Development, Long-term Outcomes and Opportunities to Optimize Youth Mental Health Trajectories
Behavioural Development, Long-term Outcomes and Opportunities to Optimize Youth Mental Health (BLOOM) is a project that aims to overcome age and diagnostic boundaries to generate person-specific longitudinal profiles of mental…
- Conditions
- Depression - Major Depressive Disorder, Bipolar, Psychosis, Eating Disorder NOS
- Trial name
- BLOOM (NCT06978452)
- Where
- Canada
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- Douglas Mental Health University Institute
Autism Spectrum Disorder
Emotional Proactive Brain Study in Adults With Autism Spectrum Condition
This project aims: to study behavioral and cerebral activity specificity (latency and amplitude of evoked potentials, time frequency maps and cerebral connectivity) in predictive process (top-down regulation) during visual…
- Trial name
- PREDEMAUT (NCT04069676)
- Testing
- EEG
- Where
- France
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Developmental Dyslexia
Prediction and Intervention in Developmental Dyslexia
The long-term goal of this study is to improve prediction of poor reading outcome at preschool age by using a combination of behavioural and neuroimaging measures and to evaluate a specific computerized training program to…
- Trial name
- LEXI (NCT02217696)
- Testing
- Computerized reading training
- Where
- Switzerland
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Autism Spectrum Disorders, Mood Disorders
Multidimensional Measurement of Psychopharmacological Treatment Response
The study examines actigraphic, observational, psychometric and associated repeated measurements obtained prior to and during psychopharmacological treatment.
- Conditions
- Autism Spectrum Disorders, Mood Disorders, Sleep Disorders, Attention Deficit Disorders
- Trial name
- NCT01184235
- Testing
- Pharmacological Intervention
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Child Psychopharmacology Institute
Dyslexia
Maturation of Auditory Processing in Children With Dyslexia Compared to Average-reading Children
The hypothesis of central auditory processing disorders has been advanced to explain the anomalies of the grapheme/phoneme combination in some dyslexia.
- Trial name
- ASTRAUCOLE (NCT02345876)
- Testing
- no intervention
- Where
- 3 sites in France
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Intellectual Disability
The Effect of Transition to Adulthood Education Program on Family Quality of Life and Perceived Stress Level
Negative emotions experienced during life processes and the burden of caregiving affect the quality of life of parents. It has been found that parents who care for their children with intellectual disability (ID) for a long time…
- Trial name
- NCT05587647
- Testing
- Transition to Adulthood Education Program
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Koç University
Down Syndrome, Speech and Language Disorder
Building Sentences With Preschoolers Who Use AAC
The focus of this investigation is to compare the effectiveness of the AAC Generative Language Intervention approach to an AAC Standard of Care condition on preschool sentence productions.
- Conditions
- Down Syndrome, Speech and Language Disorder, Speech Disorders in Children, Speech Intelligibility
- Trial name
- NCT03538925
- Testing
- AAC Generative Language Intervention, Standard of Care / Business as Usual
- Where
- 2 sites in United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Child Developmental Delay, Child Development
CASITA Intervention for Children at Risk of Delay in Carabayllo, Peru
Building on an intervention for early child development from the SPARK Center in Boston, Socios En Salud (SES) pilot tested "CASITA" a community-based package to screen and treat young children (ages 1-3 years of age) diagnosed…
- Conditions
- Child Developmental Delay, Child Development, Community Health Workers, Low Income Population
- Trial name
- NCT03010306
- Testing
- CASITA
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Disability, Intellectual, Disability Psychological
The Role of Family and Individual Factors in Going Through Adolescence - Perspective of a Healthy Child.
The goal of this observational study is to investigate the specificity of the growing up process in young people with disabled siblings.
- Conditions
- Disability, Intellectual, Disability Psychological, Disability, Developmental, Diabetes
- Trial name
- NCT06156124
- Testing
- Psychological tests and psychosocial questionnaires
- Where
- Poland
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- University of Gdansk
Intellectual Disability
Support Staff-client Interactions With Augmentative and Alternative Communication
This exploratory and observational study focuses on adults with an intellectual disability (ID) and their support workers. Two groups of clients are observed: clients using Key Word Signing, and clients using aided Augmentative…
- Trial name
- NCT02099773
- Where
- 3 sites in Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven