Clinical trials: Neurodevelopmental Disability
Nutritional Deficiencies, Developmental Delay
Project Grow Smart: Intervention Trial of Multiple Micronutrients and Early Learning Among Infants in India
Project Grow Smart evaluates the impact fortification with multiple micronutrient powders (MNP) vs. placebo (one vitamin) on child development (primary outcome) and on micronutrient status, growth, and morbidity (secondary…
- Trial name
- GrowSmart (NCT01660958)
- Testing
- MNP, Early Learning
- Where
- India
- Volunteers
- 834 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Developmental Dyslexia, Developmental Language Disorder
Dynamic Assessment of the Risk for Language and Reading Disorders in Monolingual and Multilingual Children
The project represents the completion of a part of the recently concluded European project MultiMind, in which a computer platform called MuLiMi was developed and validated.
- Trial name
- NCT06937255
- Testing
- computerized Dynamic Assessment
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Intellectual Disability, Developmental Disability
Research Engagement With People With Intellectual and Developmental Disabilities
The objectives of this project are to to build sustainable regional communities of Intellectual or Developmental Disabilities (IDD) stakeholders to provide ongoing input to research priorities, methodological processes, and…
- Conditions
- Intellectual Disability, Developmental Disability, Chronic Conditions, Multiple
- Trial name
- PCORI (NCT04182347)
- Testing
- Health Research ToolKit Development
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Microcephaly, Mental Retardation
Neurodevelopment Outcome of Newborns Exposed to Zika Virus (ZIKV) in Utero
This prospective cohort study will determine the natural history of fetal exposure to Zika virus (ZIKV) and its effects on the fetus and newborn with emphasis on neurodevelopment outcome.
- Trial name
- ZENI (NCT02943304)
- Testing
- Symptomatic pregnant women with positive RT-PCR ZIKV in serum or urine, or a positive serologic test specific for ZIKV
- Where
- Colombia
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- Universidad Industrial de Santander
Reading Disability
Executive Function in Early Childhood
Despite the fact that a substantial number of school age children struggle with both reading and math acquisition, the brain mechanisms of the overlapping aspects of reading and math skills, thought in part to be linked via…
- Trial name
- NCT03713125
- Testing
- Reading Tutoring
- Where
- United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Dyslexia
Maturation of Auditory Processing in Children With Dyslexia Compared to Average-reading Children
The hypothesis of central auditory processing disorders has been advanced to explain the anomalies of the grapheme/phoneme combination in some dyslexia.
- Trial name
- ASTRAUCOLE (NCT02345876)
- Testing
- no intervention
- Where
- 3 sites in France
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Developmental Disability
Benefits of Coding Training on Young Adults With Developmental Disabilities
The purpose of the present study is to develop and evaluate the Technology Early Career Preparation Intervention (TECH-Prep) program with African American high school students with developmental disabilities.
- Trial name
- NCT05132491
- Testing
- TECH-Prep Intervention
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Developmental Language Disorders, Developmental Articulation Disorder
Smart Computing Models, Sensors, and Early Diagnostic Speech and Language Deficiencies Indicators in Child Communication
This clinical trial aims to justify a protocol for designing and developing an automated decision-making system to support and enhance screening and early detection procedures for developmental speech/language difficulties in…
- Conditions
- Developmental Language Disorders, Developmental Articulation Disorder, Speech Disorder, Neurodevelopmental Disorder (Diagnosis)
- Trial name
- SmartSpeech (NCT06633874)
- Testing
- TD Playing the Serious Game APSOU, Non-TD Playing Serious Game
- Where
- Greece
- Volunteers
- 520 people, healthy volunteers welcome
- Sponsor
- University of Ioannina
Ankle Sprains, Motor Coordination or Function; Developmental Disorder
Project Hypnos: The Impact of a Brief Hypnosis Intervention on Single-limb Dynamic Balance in People With Chronic Ankle Instability
This study will determine the relationship of one's self-reported awareness of their body and their ankle motor control for people with chronic ankle instability.
- Trial name
- NCT06390072
- Testing
- Self-Hypnosis, Ankle Education
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ohio University
Math Learning Disability, Learning Disabilities
Intervention on Mathematical Problem-Solving Skills
The purpose of this study is to investigate neurocognitive mechanisms underlying response to intervention aimed at enhancing and remediating weaknesses in arithmetic skills in children, including those with mathematical learning…
- Conditions
- Math Learning Disability, Learning Disabilities, Learning Disabilities, Child, Dyscalculia
- Trial name
- NCT07778706
- Testing
- Speeded practice training, Arithmetic strategy training
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Stanford University
Autism Spectrum Disorder, Autism
Dynamic Quantification of Social-Visual Engagement in Autism Spectrum Disorder (ASD)
The goal of this clinical study is to learn about the utility and performance of the EarliPoint System (™): Evaluation for Autism Spectrum Disorder to diagnose and assess autism spectrum disorder (ASD) in children ages 31-96…
- Trial name
- MEASURE-ASD2 (NCT05806216)
- Testing
- EarliPoint Diagnosis, Clinically Certain Expert Clinician Diagnosis (CC-ECD)
- Where
- 9 sites in United States
- Volunteers
- 929 people, healthy volunteers welcome
- Sponsor
- EarliTec Diagnostics, Inc
Child Development, Infant Development
Expanding the Infant Achievements Intervention Through Community Partnerships
The goal of the research study is to increase teachers' implementation of evidence-based practices in Early Head Start classrooms through the delivery of a professional development (PD) training intervention.
- Conditions
- Child Development, Infant Development, Developmental Delay, Language Development
- Trial name
- NCT06312358
- Testing
- Building Capacity for Infant Achievements in Child Care
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Learning Disturbance
Complex Motor Learning With Motor Imaginary
Subjects participate in a motor learning training with a special bicycle. The experimental group proceed with 15 minutes of physical training with the bicycle and 15 minutes of rest where they use motor imaginary.
- Trial name
- NCT02999516
- Testing
- Motor imaginary, Non Motor imaginary, tDCS
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centro Universitario La Salle
Dyslexia, Developmental
Poly-unsaturated Fatty Acids and Developmental Dyslexia
Poly-unsaturated fatty acids (PUFAs) represent a component of lipids that covers a relevant role in human diet and biological functions such as provision of energy, functionality of cell membranes and tissue metabolism.
- Trial name
- NCT04287530
- Testing
- Poly-unsaturated fatty acids supplementation, Neuropsychological intervention
- Where
- 2 sites in Italy
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Developmental Delay
The CHICA Developmental Screening Study
The aims of this study are to (1) Expand and modify an existing computer-based decision support system (CHICA) to include the 2006 AAP developmental surveillance and screening algorithm; (2) Evaluate the effect of the CHICA…
- Trial name
- NCT01351077
- Testing
- CHICA DevScreen Module
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Indiana University
Dyslexia, Gait Disorders, Neurologic
Dynamic Gait Index in Children With Dyslexia
The aim of the present study is to investigate reliability in dyslexic children and compare it with healthy peers.
- Trial name
- NCT04235465
- Testing
- Dynamic Gait Index
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Marmara University
Stroke, Dyslexia, Acquired
Neurofeedback Intervention for Reading Deficits in Subacute Stroke
The overall goal of this project is to advance a biologically-based approach to treatment of reading disorders after stroke, which will expand the limits of cognitive rehabilitation.
- Trial name
- ReadingNFB (NCT04875936)
- Testing
- Motor Imagery and Real-Time fMRI Neurofeedback
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Dyslexia
Dyslexia, Motor Control and Proprioception
The investigators hypothesize that children with dyslexia present proprioceptive disorders and the purpose of the present study is to better understand relationships between motor control, proprioception and academic learnings.
- Trial name
- NCT03364010
- Testing
- Evaluation of proprioception, Evaluation of motor learning, Evaluation of written language
- Where
- France
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Vaccine Refusal, Compliance, Patient
Vaccinations and People With Disabilities
The goal of this observational study is to learn about vaccinations hesitancy, delay or avoidance in children with chronic diseases, congenital anomalies or disabilities.
- Conditions
- Vaccine Refusal, Compliance, Patient, Disability, Intellectual, Congenital Disorders
- Trial name
- NCT05749419
- Where
- Israel
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Diabetes Mellitus, Type 2, Prediabetic State
Diabetes Screening & Prevention for People With Learning (Intellectual) Disabilities:STOP Diabetes Study
People with learning (intellectual) disabilities have more health problems than the rest of the population; they are less likely to access help and have lifestyles that may increase their risk of getting diabetes (for example…
- Conditions
- Diabetes Mellitus, Type 2, Prediabetic State, Intellectual Disability
- Trial name
- NCT02513277
- Where
- United Kingdom
- Volunteers
- 930 people, healthy volunteers welcome
- Sponsor
- University of Leicester