Clinical trials: Neurodevelopmental Disability
Dyslexia, Gait Disorders, Neurologic
Dynamic Gait Index in Children With Dyslexia
The aim of the present study is to investigate reliability in dyslexic children and compare it with healthy peers.
- Trial name
- NCT04235465
- Testing
- Dynamic Gait Index
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Marmara University
Stroke, Dyslexia, Acquired
Neurofeedback Intervention for Reading Deficits in Subacute Stroke
The overall goal of this project is to advance a biologically-based approach to treatment of reading disorders after stroke, which will expand the limits of cognitive rehabilitation.
- Trial name
- ReadingNFB (NCT04875936)
- Testing
- Motor Imagery and Real-Time fMRI Neurofeedback
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Dyslexia
Dyslexia, Motor Control and Proprioception
The investigators hypothesize that children with dyslexia present proprioceptive disorders and the purpose of the present study is to better understand relationships between motor control, proprioception and academic learnings.
- Trial name
- NCT03364010
- Testing
- Evaluation of proprioception, Evaluation of motor learning, Evaluation of written language
- Where
- France
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Learning Disorders, Dyslexia
Efficacy of a Two-Year Intensive Reading Intervention for Middle School English Learners With Reading Difficulties
This study investigates the efficacy of a reading comprehension intervention for English learners in Grades 6 and 7 with reading difficulties.
- Trial name
- TCLD (NCT03695068)
- Testing
- RISE Intervention
- Where
- 2 sites in United States
- Volunteers
- 840 people
- Sponsor
- University of Houston
Premature Birth, Brain Injuries
S100B as a Marker of Brain Injury of Preterm Infants
The improvement of treatment of preterm neonates improved their survival, however there is still significant portion of preterm infants (specifically very preterm infants) that suffers from brain insults and as a result…
- Conditions
- Premature Birth, Brain Injuries, Leukomalacia Periventricular, Developmental Disabilities
- Trial name
- PTS100B (NCT02082535)
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Sheba Medical Center
Intellectual Disability, Overweight and Obesity
Cooking Skills to Improve Long-Term Weight Loss in Young Adults With Intellectual Disabilities
The goal of this study is to see if adding hands-on cooking classes to a weight management program (called Chef-ID) helps young adults with intellectual disabilities lose more weight and keep it off compared to a standard weight…
- Trial name
- CHEF-ID (NCT06961591)
- Testing
- Weight Loss Plus Cooking, Traditional Weight Loss
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- University of Kansas Medical Center
Reading Disability
University of Washington Reading & Dyslexia Research Program
Subjects are recruited for a pre-kindergarten education program focusing on early literacy skills. Primary outcomes are improvement in letter knowledge and changes in brain response to text.
- Trial name
- NCT03945097
- Testing
- preK
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Washington
Intellectual Developmental Disorder, Malformations
The Belgian Genome Resource to Resolve Rare Diseases
Whole-exome (WES) or whole-genome sequencing (WGS) are recommended as first- or second-tier molecular tests for patients with developmental disorders (DD), but the clinical utility of WGS continues to be debated.
- Conditions
- Intellectual Developmental Disorder, Malformations, Dysmorphia, Developmental Delay (Disorder)
- Trial name
- BeSolveRD (NCT07051213)
- Testing
- Whole exome sequencing, Whole genome Sequencing
- Where
- Belgium
- Volunteers
- 567 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Developmental Dyslexia, Developmental Spelling Disorder
Remotely Controlled Intervention for Developmental Reading and Spelling Disorders Through the Tachidino Platform
The study aims to document the effects of the intervention system for specific reading and spelling disorders, currently in use at Scientific Institute (IRCCS) Medea as an innovative intervention model in e-health mode.
- Trial name
- NCT04382482
- Testing
- Tachidino
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- IRCCS Eugenio Medea
Cardiology, Infant Development
Developmental Intervention for Hospitalized Newborns With Congenital Heart Disease
The proposed study includes a newborn developmental intervention to improve neurodevelopmental (ND) and medical outcomes for infants with congenital heart disease (CHD) with improved parent well-being.
- Conditions
- Cardiology, Infant Development, Development Delay
- Trial name
- NCT05885113
- Testing
- NIDCAP Developmental Care
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Boston Children's Hospital
Vaccine Refusal, Compliance, Patient
Vaccinations and People With Disabilities
The goal of this observational study is to learn about vaccinations hesitancy, delay or avoidance in children with chronic diseases, congenital anomalies or disabilities.
- Conditions
- Vaccine Refusal, Compliance, Patient, Disability, Intellectual, Congenital Disorders
- Trial name
- NCT05749419
- Where
- Israel
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Attention Deficit in Intellectual Disability
Outcomes Measures in Intellectual Disability
Objective quantitative primary endpoints are lacking in Clinical trials in intellectual disability. We propose to develop quantitative interactive attention evaluation criteria in patients with intellectual disability by using…
- Trial name
- EVALDI (NCT03878251)
- Testing
- Quantitative attention evaluation criteria in intellectual disability
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Diabetes Mellitus, Type 2, Prediabetic State
Diabetes Screening & Prevention for People With Learning (Intellectual) Disabilities:STOP Diabetes Study
People with learning (intellectual) disabilities have more health problems than the rest of the population; they are less likely to access help and have lifestyles that may increase their risk of getting diabetes (for example…
- Conditions
- Diabetes Mellitus, Type 2, Prediabetic State, Intellectual Disability
- Trial name
- NCT02513277
- Where
- United Kingdom
- Volunteers
- 930 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Intellectual Disability, Developmental Disability
Written Language Intervention for Adults With Intellectual and Developmental Disabilities
The purpose of this study is to evaluate the effects of a written language intervention using functional texts for young adults with intellectual and developmental disabilities.
- Trial name
- NCT05851937
- Testing
- Written language intervention
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Baylor University
Communication Disabilities
Improving Communication and Healthcare Outcomes for Patients With Communication Disabilities
In the United States, 14% of all adults report a speech, language, voice, and/or hearing disability (collectively known as communication disabilities, CD).
- Trial name
- NCT04697212
- Testing
- Healthcare team- + patient-directed intervention, Healthcare team-directed intervention
- Where
- 5 sites in United States
- Volunteers
- 687 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Global Developmental Delay
Design and Implementation of a Carer Aromatherapy Training (CAT) Program for Children With Global Developmental Delay in Hong Kong: A Mixed Qualitative Study Using the COM-B Framework
This project aims to design and implement a Carer Aromatherapy Training (CAT) program, guided by the Capability, Opportunity, Motivation and Behaviour (COM-B) model, to empower carers with safe and effective aromatherapy…
- Trial name
- CAT programme (NCT07800689)
- Testing
- Carer Aromatherapy Training (CAT) program and home massage with massage oil with the mixture of Petitgrain Mandarin (Citrus reticulate) essential oil and fractionated coconut oil
- Where
- Hong Kong
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hong Kong Metropolitan University
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
The Coordination of Rare Diseases at Sanford (CoRDS) is an international patient registry that serves as a centralized resource for rare disease research.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Prader-Willi Syndrome, Aggression
Guanfacine Extended Release for the Reduction of Aggression and Self-injurious Behavior Associated With Prader-Willi Syndrome
This is a placebo-controlled clinical trial to assess whether Guanfacine Extended Release (GXR) reduces aggression and self injurious behavior in individuals with Prader Willi Syndrome (PWS).
- Conditions
- Prader-Willi Syndrome, Aggression, Self-Injurious Behavior, Pathologic Processes
- Trial name
- PWS-GXR (NCT05657860)
- Testing
- Guanfacine Extended Release
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Maimonides Medical Center
Gaucher's Disease
Effects of Enzyme Replacement in Gaucher's Disease
Gaucher disease is a lysosomal storage disease resulting from glycocerebroside accumulation in macrophages due to a genetic deficiency of the enzyme glucocerebrosidase.
- Trial name
- NCT00001289
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Intellectual Disability, Quality of Life
The Effect of Gardening Activities on the Quality of Life of Students With Mild Intellectual Disability
This study will be conducted to determine the effect of gardening activities applied to mildly intellectually disabled secondary school students on their quality of life and to examine their views on these activities in depth.
- Trial name
- NCT07504874
- Testing
- Horticultural activity
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ordu University
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