Clinical trials: Neurodevelopmental Disorder
Attention Deficit Hyperactivity Disorder
An Open Label Phase I/II Study of the Safety and Dopamine Transporter Binding Properties of C-11 Altropane in Normal Human Subjects and in Subjects With ADHD
The primary objective of this study is to evaluate the Binding Potential in subjects with ADHD and adults without ADHD: the intent being to demonstrate that C-11 Altropane PET can be used to differentiate adults with ADHD from…
- Trial name
- NCT00302380
- Testing
- PET imaging using C-11 altropane as the ligand.
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Autistic Disorder, Autism Spectrum Disorder
A Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Food Effect of RO6953958 in Healthy Participants
This study will evaluate the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of single- and multiple-ascending doses (SAD (Part 1) and MAD (Part 2)) and food effect (FE) of RO6953958 following oral…
- Conditions
- Autistic Disorder, Autism Spectrum Disorder, Child Development Disorders, Pervasive, Mental Disorders
- Trial name
- NCT04475848
- Testing
- RO6953958, Midazolam
- Where
- United Kingdom
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Gut Microbiome, Gastrointestinal Microbiome
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records.
- Conditions
- Gut Microbiome, Gastrointestinal Microbiome, Autism, Autism Spectrum Disorder
- Trial name
- NCT04031469
- Testing
- There is no intervention in this study
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- ProgenaBiome
Autism Spectrum Disorder, Disruptive Behavior
RUBIES in Educational Settings
The proposed three-year pilot randomized trial aims to test the effectiveness of the newly-redesigned paraeducator-delivered RUBI for use in Educational Settings (RUBIES) intervention compared to usual care training in reducing…
- Trial name
- RUBIES (NCT05093686)
- Testing
- RUBIES, Usual Care Training
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Attention Deficit Hyperactivity Disorder
Food Additives Effects on EEG Profiles in College Students With ADHD
The purpose of this study is to examine the effects of food additives on college students with ADHD. This study could potentially answer an important question which still remains unanswered as to whether certain food additives…
- Trial name
- NCT03342469
- Testing
- Artificial Food Coloring
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- American University
Autism Spectrum Disorders
Genetics, Brain Structure and Thinking Skills in Autism
The purpose of this research is to better understand the genetic, biochemical, cognitive and behavioral symptom abnormalities that contribute to autism spectrum disorders.
- Trial name
- NCT01451983
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Attention Deficit Hyperactivity Disorder
Metabolic Pathway of Tryptophan and Executive Dysfunction in Children With Attention Deficit Hyperactivity Disorder
The present project is to identify the relationship between ADHD and the metabolites of tryptophan.
- Trial name
- NCT03901859
- Where
- Taiwan
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Generalized Anxiety Disorder, Social Phobia
Computerized Cognitive Behavioral Therapy for Childhood Anxiety in Community Health Centers
This study will examine the efficacy of a computerized cognitive behavioral therapy (CCBT) program for children with anxiety disorders in community health centers.
- Conditions
- Generalized Anxiety Disorder, Social Phobia, Separation Anxiety Disorder
- Trial name
- NCT01416805
- Testing
- Computerized Cognitive Behavioral Therapy, Treatment as usual
- Where
- 4 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Child Behavior, Child Behavior Problem
Self-Concept Reinforcement for Early School Readiness
The goal of this pilot randomized controlled trial is to evaluate a self-concept intervention (Self-Concept Reinforcement for Early School Readiness (SCR4ESR)) in young African American children using experimental and mixed…
- Conditions
- Child Behavior, Child Behavior Problem, Child Behavior Disorders
- Trial name
- SCR4ESR (NCT06084910)
- Testing
- Self-Concept Reinforcement for Early School Readiness, Reach Out and Read
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
ADHD - Attention Deficit Disorder With Hyperactivity, ADHD
Research on the Development, Implementation Effect and Neural Mechanism of a Physical Intervention Program for College Students With ADHD Based on the Characteristics of Balance Dysfunction
Background: Attention deficit/hyperactivity disorder is a common neurodevelopmental disorder. Its core symptoms and related executive function, emotional and motor coordination problems often persist into adulthood, significantly…
- Conditions
- ADHD - Attention Deficit Disorder With Hyperactivity, ADHD, ADHD - Combined Type, ADHD - Inattentive Type
- Trial name
- NCT07499427
- Testing
- Aerobic Treadmill Training, Progressive Balance Training, Cognitive-Balance Dual-Task Training
- Where
- China
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Wuhan Sports University
Movement Disorder
Cerebral Activity Related to Primary Motor Stereotypies in Children: An EEG Study.
Background: Motor stereotypies are a movement disorder characterized by involuntary, repetitive, and rhythmic movements. These movements have a predictable pattern and seem purposeful, but they serve no obvious function, tend to…
- Trial name
- NCT01037361
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Autism
Parent Language Intervention for Autism
Improving social communication outcomes for children with autism spectrum disorders (ASD) has important public health implications.
- Trial name
- NCT02632773
- Testing
- Responsive Intervention, Directive Intervention
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Autistic Disorder
A Chart Review to Evaluate the Safety and Efficacy of MeRT on Subjects With ASD
The purpose of this study is to evaluate the safety and efficacy of Magnetic EEG/ECG-Guided Resonance Therapy (MeRT) on subjects with Autism Spectrum Disorder (ASD).
- Trial name
- NCT02758496
- Testing
- MeRT Efficacy Chart Review
- Where
- United States
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Wave Neuroscience
Developmental Coordination Disorder
Rhythmic Interlimb Coordination in Children with Developmental Coordination Disorder
This study is a case-controlled observational study, involving children with Developmental Coordination Disorder (DCD) and typically developing children with an age from 8 up to 12 years old.
- Trial name
- NCT04891562
- Testing
- interlimb coordination of the lower limbs and synchronization
- Where
- Belgium
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Stuttering, Developmental, Dyslexia
Investigating Individual Differences in Speech Motor Skills in Neurotypical Speakers and Persons With Disordered Speech
This study aims to understand how people use different types of feedback to control their speech. When an individual speaks, the brain relies on several systems at the same time, such as sensory systems that monitor an…
- Conditions
- Stuttering, Developmental, Dyslexia, Healthy Participants
- Trial name
- NCT07459803
- Testing
- Unpredictable auditory feedback perturbation: 2 behavioral sessions, Unpredictable auditory feedback perturbation during tCS: 3 behavioral sessions, Sustained F1 auditory feedback perturbation
- Where
- 2 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
ADHD
Prevalence of Attention Deficit Hyperactivity Disorder and Its Comorbidities
Estimate the prevalence of attention deficit hyperactivity disorder and comorbid psychiatric disorder among primary school students in New Valley governorate.
- Trial name
- NCT06146595
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Assiut University
Autism, Attention Deficit Hyperactivity Disorder
a2 Milk for Autism and Attention-deficit Hyperactivity Disorder (ADHD)
Under double-blind, placebo-controlled, cross-over conditions, the short-term effects of use of A1 beta casein free milk (a2 milk) and milk containing A1 beta casein will be compared in a sample of pre-pubescent boys diagnosed…
- Conditions
- Autism, Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder
- Trial name
- A2MT (NCT02911194)
- Testing
- a2 milk, a1 containing milk
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Attention Deficit Hyperactivity Disorder (ADHD)
The Relationship of Essential Fatty Acids to Adult ADHD: The OCEAN Study (Oils and Cognitive Effects in Adult ADHD Neurodevelopment)
Brief summary The aim of the study is to provide preliminary data on the relationship of Essential Fatty Acids (EFAs) to cognitive and electrophysiological measures of brain and behavioural functions in adults with attention…
- Trial name
- OCEAN (NCT01750307)
- Testing
- Experimental fatty acid supplementation
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- King's College London
Neurodevelopmental Disorders, Cystic Fibrosis
Neurodevelopmental Assessment of Infants With Cystic Fibrosis
Infants included in the study will be divided into two groups as healthy infants and cystic fibrosis infants . Demographic, natal and postnatal information of the infants will be available from patient files.
- Trial name
- NCT03577756
- Testing
- Neurodevelopmental assessments
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Autism Spectrum Disorder, Neurodevelopmental Disorders
Evaluation of a Novel Intervention for Infants At Risk for Neurodevelopmental Disorders
This study entails a "proof of concept" evaluation of a novel intervention, Parents and Infants Engaged (PIE), for prodromal infants at-risk for neurodevelopmental disorders (NDs).
- Trial name
- PIE (NCT03388294)
- Testing
- Parents and Infants Engaged
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
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