Clinical trials: Neurodevelopmental Disorder
Autism Spectrum Disorder, Language Development
HR-EEG Contribution in Prognostic Evaluation of Language Development in Children With ASD
The goal of this prospective observational multicentric cohort study is to evaluate the clinical prognostic value of the speech tracking score of language development in children with ASD aged from 3 years to 4 years and half at…
- Conditions
- Autism Spectrum Disorder, Language Development, Neurocognitive Disorders, Child Language
- Trial name
- EE-TSA-LANG (NCT05586672)
- Testing
- EEG-HR, ADI-R, ADOS-2
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Etablissement Public de Santé Barthélemy Durand
Developmental Delay, Preterm Children
Home-based Visual-motor Training Program on Kindergarteners
The study aims to investigate the feasibility and effectiveness of the traditional and computerized home-based visual-motor training programs on at-risk kindergarteners.
- Trial name
- NCT05605977
- Testing
- Traditional visual-motor training program, Computerized visual-motor training program
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Attention-deficit/Hyperactivity Disorder
Language-based Learning Skills and Attention Deficit Hyperactivity Disorder (ADHD): Impact of Treatment With Sustained-release Guanfacine
This study is investigating the effect of sustained-release guanfacine (Intuniv) on language-based learning skills in children age 6-12 who are diagnosed with attention deficit hyperactivity disorder (ADHD).
- Trial name
- NCT01146002
- Testing
- Guanfacine (sustained release)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Neurology Group of Bergen County, P.A.
Fragile X Syndrome, Angelman Syndrome
Parent and Infant Inter(X)Action Intervention (PIXI)
The objective is to develop and test, through an iterative process, an intervention to address and support the development of infants with a confirmed diagnosis of a neurogenetic disorder with associated developmental delays or…
- Conditions
- Fragile X Syndrome, Angelman Syndrome, Prader-Willi Syndrome, Dup15Q Syndrome
- Trial name
- NCT03836300
- Testing
- Parent-Infant Inter(X)action Intervention (PIXI)
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- RTI International
Autism
Assessment Of Spinal Posture, Balance And Ankle Muscle Shortness İn Children With Autism
The aim of this study is to evaluate spinal posture, mobility, balance and ankle muscle shortness in children with autism. The study will feature two groups, First group will consist of children with autism Second group will…
- Trial name
- NCT06995716
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Developmental Coordination Disorder
Rhythmic Motor Learning in Children With Developmental Coordination Disorders
The importance of play and physical activity include many benefits on positively improving health and well-being, enhancing children's and young people's thinking and performance in school, improving their sleep and enabling…
- Trial name
- EPIC2 (NCT03150784)
- Testing
- EPIC Club
- Where
- 5 sites in United Kingdom
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Oxford Brookes University
Attention Deficit/Hyperactivity Disorder
Exercise Effects in Children With Attention Deficit Hyperactivity Disorder
The study will investigate catecholamines responses, and cognitive effects of exercise in children with attention deficit hyperactivity disorder, and the effect of exercise training on these measures.
- Trial name
- NCT00945971
- Testing
- Physical activity
- Where
- Israel
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Autism Spectrum Disorder, Parent-Child Relations
RCT of a Mobile Phone App-based Intervention for Parents of Children With Autism Spectrum Disorder (ASD)
The objective of this study is to evaluate the effectiveness of a 6-week mobile app-based intervention in empowering and supporting Chinese parents of ASD children through knowledge and skills transfer and mindfulness training…
- Trial name
- NCT05927116
- Testing
- Mobile phone app-based intervention for supporting and empowering parents of children with autism spectrum disorder (ASD)
- Where
- Hong Kong
- Volunteers
- 852 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Epilepsy, Pregnancy
Maternal Outcomes and Neurodevelopmental Effects of Antiepileptic Drugs (MONEAD)
Epilepsy is one of the most common neurological disorders affecting women of childbearing age. Poor pregnancy outcomes are increased in these women and their children.
- Trial name
- MONEAD (NCT01730170)
- Where
- 20 sites in United States
- Volunteers
- 565 people, healthy volunteers welcome
- Sponsor
- Stanford University
Attention Deficit Hyperactivity Disorder
A Trial of Computer-based Attention-training Systems in Children With Attention Deficit Hyperactivity Disorder (ADHD)
This study examines the efficacy of two computer-based training systems to teach children with ADHD to attend more effectively.
- Trial name
- CATS (NCT00956605)
- Testing
- Computer attention training systems for children with ADHD
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Tufts Medical Center
Heart Defects, Congenital
Impact of Congenital Heart Disease on Neurodevelopmental Outcome
The project aims toward clarifying the underlying mechanism and the long-term impact of congenital heart disease on neurodevelopment.
- Trial name
- NCT03871881
- Testing
- Magnetic Resonance Imaging, Neuropsychological assessment
- Where
- Denmark
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Autism Spectrum Disorder, Language Development
Predicting Language and Literacy Growth in Children With ASD Using Statistical Learning
The goal of this observational study is to test a reciprocal relationship between statistical learning and the development of language and literacy in first-graders with autism and their non-autistic peers.
- Conditions
- Autism Spectrum Disorder, Language Development, Literacy
- Trial name
- PLAUSL (NCT06332144)
- Testing
- Structural vs. Random sequences of stimuli, Intact vs. Degraded speech, Repeating 5-syllable nonwords or 2-syllable nonwords
- Where
- 2 sites in United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Northeastern University
Attention Deficit Hyperactivity Disorder
The Effects of Long-acting Methylphenidate on Academic Activity and Related Constructs in Children With ADHD
This study aims at investigating the direct effects of methylphenidate on school performance of primary school children. Although behavioral effects of this frequently prescribed drug are thoroughly studied (and confirmed), the…
- Trial name
- NCT02501798
- Testing
- Methylphenidate
- Where
- Netherlands
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- VU University of Amsterdam
Autism, Infantile
The Effect of Acceptance and Commitment Therapy
In this randomized control study, investigators will evaluate the effectiveness of the Acceptance and Commitment Therapy (ACT) matrix behavioral protocol compared to Parent Training (PT) programs in improving the psychological…
- Trial name
- ASDMatrix (NCT04909658)
- Testing
- ACT Matrix, PT Protocol
- Where
- Italy
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- S.Anna Rehabilitation Institute
Anxiety, Separation
A Comparison of Two Doses of Intranasal Dexmedetomidine for Premedication in Children
The purpose of the study is to determine if 4mcg/kg of intranasal dexmedetomidine is better than 2mcg/kg in successfully sedating a child prior to induction of anesthesia.
- Trial name
- NCT02459509
- Testing
- Dexmedetomidine
- Where
- Hong Kong
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Cardiac Conditions, Connective Tissue Diseases
The Genetics Navigator: Evaluating a Digital Platform for Genomics Health Services
Genetic testing (GT) (including targeted panels, exome and genome sequencing) is increasingly being used for patient care as it improves diagnosis and health outcomes.
- Conditions
- Cardiac Conditions, Connective Tissue Diseases, Retinal Disease, Epilepsy in Children
- Trial name
- NCT06455384
- Testing
- Genetics Navigator, Standard Care with Genetics Professionals
- Where
- 3 sites in Canada
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Depression - Major Depressive Disorder, Bipolar
Behavioural Development, Long-term Outcomes and Opportunities to Optimize Youth Mental Health Trajectories
Behavioural Development, Long-term Outcomes and Opportunities to Optimize Youth Mental Health (BLOOM) is a project that aims to overcome age and diagnostic boundaries to generate person-specific longitudinal profiles of mental…
- Conditions
- Depression - Major Depressive Disorder, Bipolar, Psychosis, Eating Disorder NOS
- Trial name
- BLOOM (NCT06978452)
- Where
- Canada
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- Douglas Mental Health University Institute
Attention Deficit Hyperactivity Disorder, Psychiatric Diagnosis
Neurophysiological Marker of ADHD in Children
This study investigated quantitative electroencephalography (QEEG) subtypes as auxiliary tools to assess Attention Deficit Hyperactivity Disorder (ADHD).
- Conditions
- Attention Deficit Hyperactivity Disorder, Psychiatric Diagnosis, Diagnosis, Psychiatric
- Trial name
- NCT04467658
- Testing
- electroencephalography absolute delta power, electroencephalography relative delta power, electroencephalography absolute theta power
- Where
- South Korea
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Daegu Catholic University Medical Center
Autism Disorder
Triadic Interactions of Families With Autism and Oxytocin
The study will investigate the effects of an intranasal administration of oxytocin (OT) to parents of children with autism spectrum disorders (ASD) on the quality of mother-father-child interactions.
- Trial name
- TAO (NCT01912378)
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Autism Spectrum Disorder
The Relationship Between Social Memory Disorders and Sleep Spindles in Children With Autism Spectrum Disorder
Research background and project basis Autism spectrum disorder (ASD) is a lifelong neurodevelopmental disorder characterized by social disorders and repetitive stereotypical behavior.
- Trial name
- NCT06306378
- Testing
- social memory levels and spindle levels
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
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