Clinical trials: Neurodevelopmental Disorder
Attention Deficit Hyperactivity Disorder
Adults With Attention Deficit Hyperactivity Disorder (ADHD): Validation of a Clinical Interview and Screening Instruments in French
ADHD is a neurodevelopmental disorder that affects about 5% of school-age children and 3.5% of adults worldwide. This condition is under-recognised in France and other European countries and, therefore, under-diagnosed.
- Trial name
- NCT01553695
- Testing
- questionary
- Where
- France
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Down Syndrome, Speech and Language Disorder
Building Sentences With Preschoolers Who Use AAC
The focus of this investigation is to compare the effectiveness of the AAC Generative Language Intervention approach to an AAC Standard of Care condition on preschool sentence productions.
- Conditions
- Down Syndrome, Speech and Language Disorder, Speech Disorders in Children, Speech Intelligibility
- Trial name
- NCT03538925
- Testing
- AAC Generative Language Intervention, Standard of Care / Business as Usual
- Where
- 2 sites in United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Language Disorders in Children
Let's Know!2: Language-focused Intervention for Children at Risk of Comprehension Difficulties
In the proposed project, the investigators will conduct a multisite randomized controlled trial (RCT) to determine the efficacy of Let's Know!2, a small-group, language focused comprehension intervention, on children's lower- and…
- Trial name
- LK!2 (NCT05133479)
- Testing
- Let's Know! small-group or TierL 2 Intervention
- Where
- 2 sites in United States
- Volunteers
- 241 people, healthy volunteers welcome
- Sponsor
- MGH Institute of Health Professions
Disability Physical, Developmental Disability
Virtual Reality Exercise in a Community Highschool for Children With Disabilities
The purpose of this study is to work with a community engagement group to develop and pilot a protocol for a virtual reality exergaming program for children with special needs at a high school.
- Conditions
- Disability Physical, Developmental Disability, Physical Inactivity
- Trial name
- NCT05935982
- Testing
- Virtual reality exercise
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Autism Spectrum Disorder, Mental Health Issue
Access to Tailored Autism Integrated Care Pilot Study
Children with autism spectrum disorder (ASD) represent a rapidly growing, high-priority clinical population highlighted by the NIMH and Interagency Autism Coordinating Committee due, in part, because they have multiple service…
- Trial name
- ATTAIN (NCT04293627)
- Testing
- ATTAIN
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Brain Development, Behavior Disorders, Child
The Brain Mechanism of Social Emotion and Communication in Infants Aged 0 to 6 Years
This study explores the relationship between brain development and infants' social emotion and communication ability, as well as the role of genetic factors and maternal exposure during pregnancy (e.g., environmental exposures…
- Conditions
- Brain Development, Behavior Disorders, Child, Intellectual Developmental Disorders
- Trial name
- NCT05040542
- Testing
- maternal exposure during pregnancy
- Where
- China
- Volunteers
- 3,001 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Attention Deficit Hyperactivity Disorder
A Controlled Study of Solriamfetol for Attention Deficit Hyperactivity Disorder (ADHD) in Adults
A double-blind, placebo controlled study of solriamfetol for adults age 18 to 65 with diagnosis of Attention Deficit Hyperactivity Disorder.
- Trial name
- NCT04839562
- Testing
- Solriamfetol 75 MG, Solriamfetol 150 MG
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Prosocial Behavior, Anxiety Disorders and Symptoms
Promoting Social-emotional Development and Self-esteem in Primary School Students
This is an effectiveness study into a program ("HiRO") for improving social-emotional development, self esteem and the perceived classroom peer context in primary school students (aged 4-13 years).
- Conditions
- Prosocial Behavior, Anxiety Disorders and Symptoms, Attention Deficit Hyperactivity Disorder, Healthy
- Trial name
- NCT06019429
- Testing
- HiRO, HiRO +judo, School as usual
- Where
- Netherlands
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Universiteit Leiden
Tourette Syndrome
Exploration of Glutamatergic System With PET Radiotracer in Gilles de la Tourette Patients: Pilot Study (GlutaTour)
Gilles de la Tourette syndrome is a neuropsychiatric disorder characterized by motor and vocal tics often associated with psychiatric comorbidities (obsessive compulsive disorder, anxiety and depressive syndrome, impulsivity).
- Trial name
- GlutaTour (NCT03681795)
- Testing
- Experimental MRI exam and PET scan exam with radiotracer
- Where
- France
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Attention Deficit Hyperactivity Disorder
Meta-cognitive Functional Intervention for Adults With ADHD: A Pilot Efficacy Study
The purpose of this study is to examine the initial efficacy of a psycho-social, metacognitive-functional intervention for Adults (Cog-Fun - A) with Attention Deficit Hyperactivity Disorder (ADHD).
- Trial name
- NCT02681575
- Testing
- Cog-Fun - A
- Where
- Israel
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Disruptive Mood Dysregulation Disorder, Attention Deficit Hyperactivity Disorder
Characterization and Brain Mechanisms of Frustration in Youth With Severe Irritability or Attention Deficit Hyperactivity Disorder (ADHD)
Background: Irritability is an elevated proneness to anger. Children with irritability have difficulty tolerating frustration. They get angry and have temper outbursts more easily than their others their age.
- Conditions
- Disruptive Mood Dysregulation Disorder, Attention Deficit Hyperactivity Disorder, Normal Physiology
- Trial name
- NCT05357495
- Testing
- Affective Posner fMRI frustration induction task
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Autism Spectrum Disorder
Trial of Autism Parent Navigator Program
To address the dual needs of parents for support in navigating Autistic Spectrum Disorder (ASD) services and maintaining positive family functioning, the investigators propose to test Autism Parent Navigators (APN), an innovative…
- Trial name
- APN (NCT04744428)
- Testing
- Autism Parent Navigators, Peer mentoring
- Where
- United States
- Volunteers
- 388 people, healthy volunteers welcome
- Sponsor
- Penn State University
Attention-Deficit/Hyperactivity Disorder
Role of Circadian and Homeostatic Systems in the Regulation of Wakefulness in Adult Patients With Attention Deficit Disorder With or Without Hyperactivity
In a previous protocol, we highlighted an excessive daytime sleepiness at the Maintenance of Wakefulness Tests (MWT) in 36% of adult Attention Deficit Disorder with or without Hyperactivity (ADHD) patients.
- Trial name
- VEILLETDAH (NCT02217371)
- Testing
- Neuropsychological tests
- Where
- France
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Developmental Language Disorder, Specific Language Impairment
Retrieval-Based Word Learning in Developmental Language Disorder: Verb Learning
Children with developmental language disorder (DLD; also referred to as specific language impairment) experience a significant deficit in language ability that is longstanding and harmful to the children's academic, social, and…
- Conditions
- Developmental Language Disorder, Specific Language Impairment, Language Development
- Trial name
- NCT06001866
- Testing
- Retrieval-based verb learning: Repeated Spaced Retrieval condition, Retrieval-based verb learning: Repeated Study condition
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Purdue University
Development, Child, Motor Skills Disorders
Motor and Visual Development in 2 Year Olds
It is a study where investigators are going to measure variables related to motor development and vision through objective tests in children with typical development of two years of age.
- Conditions
- Development, Child, Motor Skills Disorders, Visual Disorder
- Trial name
- NCT04277754
- Testing
- Observational
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Seville
Developmental Coordination Disorder, Autism Spectrum Disorder
An Explorative RVA of the Motor Development of Children With DCD <2y
This study compares motor development in three groups of infants (controls, DCD, DCD+ASD) before the age of 2 years using retrospective video analysis of infants in home video contexts.
- Trial name
- RVA_DCD (NCT04126395)
- Testing
- Movement Assessment Battery for Children 2(M-ABC-2), Developmental Coordination Disorder - Questionnaire (DCD-Q), Social Responsiveness Scale 2 (SRS-2)
- Where
- 2 sites in Belgium, Canada
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University Ghent
Developmental Language Disorder, Language Disorders in Children
The Influence of Immersive Virtual Field Trips on Academic Vocabulary
The purpose of this study is to investigate an immersive virtual field trip (iVFT) on topic specific academic vocabulary for students with developmental language disorder (DLD).
- Trial name
- NCT05242575
- Testing
- The information provided in the iVFT and control book parallel one another.
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Salus University
Attention Deficit Hyperactivity Disorder, ADHD
Female Experiences and Brain Activity
The Female Experiences and Brain Activity study will investigate how different groups of people process information in different ways.
- Conditions
- Attention Deficit Hyperactivity Disorder, ADHD, Bipolar Disorder
- Trial name
- FEBA (NCT01395160)
- Where
- 2 sites in United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- King's College London
Neurodevelopmental Disorder (Diagnosis), Epilepsy
Characterization of Neurocognitive Profiles in Neurodevelopmental Disorders and Epilepsy: a Transdiagnostic Approach
Neurodevelopmental disorders (NDDs) are early-onset conditions affecting personal, social, and academic functioning, with high comorbidity rates and shared neurobiological traits.
- Trial name
- DIS-Neurodev (NCT06877260)
- Testing
- Computer based task with EEG
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Autism Spectrum Disorder
Characterizing Occupational Therapy Intervention for Children With Autism Spectrum Disorders
This pilot study aims to identify behavioral and neural measures of sensory processing and attention associated with routine occupational therapy intervention for children with autism spectrum disorders.
- Trial name
- NCT05480605
- Testing
- Occupational Therapy
- Where
- 2 sites in United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Ohio State University
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