Clinical trials: Neurodevelopmental Disorder
Dyslexia
taVNS for Letter Learning in Dyslexia
This is a pilot study to establish feasibility of transcutaneous auricular vagus nerve stimulation (taVNS) for improving letter-learning in adolescents with dyslexia.
- Trial name
- NCT06127550
- Testing
- active taVNS
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Florida
Chronic Pain, Chronic Pain Syndrome
Outcomes Mandate National Integration With Cannabis as Medicine
This will be a multistate, multicenter clinical study to determine the efficacy and safety of medical cannabis for a wide variety of chronic medical conditions.
- Conditions
- Chronic Pain, Chronic Pain Syndrome, Chronic Pain Due to Injury, Chronic Pain Due to Trauma
- Trial name
- OMNI-Can (NCT03944447)
- Testing
- Cannabis, Medical, RYAH-Medtech Inhaler
- Where
- 17 sites in United States
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- OMNI Medical Services, LLC
Mental Disorders, Healthy Control
Psychiatric Multi-omics and Neuroimaging Project
This study focuses on the structure and function of the brain and gene expression in peripheral blood of patients with schizophrenia, to explore the interaction and influence between the three.
- Trial name
- PMNP (NCT06580860)
- Testing
- Antipsychotic drugs, antidepressants, mood stabilizers, and sleep aids
- Where
- China
- Volunteers
- 1,899 people, healthy volunteers welcome
- Sponsor
- mingjun Zhong
Child Behavior Problem, Child Behavior Disorders
Positive Parenting Program in Foster Care
The purpose of the study is to evaluate early implementation outcomes of a positive parenting program, Child Adult Relationship Enhancement in Primary Care (PriCARE), in the foster care setting and to assess the efficacy of…
- Conditions
- Child Behavior Problem, Child Behavior Disorders, Parenting, Foster Care
- Trial name
- NCT03910491
- Testing
- PriCARE
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Post-Acute COVID-19 Syndrome, ME/CFS
Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research
The unhide® Project is a non-interventional, longitudinal research study designed to establish a secure data repository of demographic, health, and lifestyle information from individuals with brain inflammation and related…
- Conditions
- Post-Acute COVID-19 Syndrome, ME/CFS, Rheumatic Arthritis, Juvenile Rheumatoid Arthritis (JRA)
- Trial name
- NCT04806620
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Brain Inflammation Collaborative
Child Development, Child Behavior Disorders
Promoting Infant Mental Health in Foster Care
This study will evaluate the effectiveness of the Promoting First Relationships (PFR) program versus an Early Education Support (EES) program in promoting infant well-being, preventing emotional and behavioral problems…
- Conditions
- Child Development, Child Behavior Disorders, Reactive Attachment Disorder
- Trial name
- NCT00339365
- Testing
- Promoting First Relationships Program, Early Education Support Program
- Where
- United States
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- University of Washington
Therapeutic Recreation, Intellectual Disability
The Effects of Therapeutic Recreation Activities on Aberrant Behaviours of Individuals With Intellectual Disabilities
The aim of this study was to determine the effect of Therapeutic Recreation Activities on Aberrant Behavior of Adolescents With Intellectual Disabilities.
- Conditions
- Therapeutic Recreation, Intellectual Disability, Recreational Activities, Aberrant Behaviors
- Trial name
- NCT04546464
- Testing
- Therapeutic Recreation Program
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Typical Development, Risk of Dysgraphia
Graphomotor Intervention Program for Handwriting Difficulties Prevention in School-Age
12-30% of children present handwriting difficulties, which has negative repercussions on their school career. For this reason, it is fundamental to bet on their prevention.
- Conditions
- Typical Development, Risk of Dysgraphia, Dysgraphia
- Trial name
- NCT03699800
- Testing
- Graphomotor intervention program
- Where
- Portugal
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Évora
Developmental Delay
Development and Effectiveness of Home-based Programs for Preschool Children With Developmental Delay
Early intervention refers to the provision of early detection, early diagnosis, and early intervention for infants and young children with special needs.
- Trial name
- NCT02115334
- Testing
- professional therapists delivering the PHPA, parents executing the PHPA, health education
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Autism Spectrum Disorder, Early Intervention
Biomarkers Trajectories of Early Intervention in Siblings of Children with Autism Spectrum Disorder
This project deals with essential challenges in the context of Autism Spectrum Disorder benefiting from a prospective design in childhood, early intervention and a cutting-edge experimental techniques.
- Trial name
- NCT05614206
- Testing
- Behavioral intervention based on Applied Behavior Analysis principles
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Developmental Coordination Disorder
Rhythmic Motor Learning in Children With Developmental Coordination Disorders
The importance of play and physical activity include many benefits on positively improving health and well-being, enhancing children's and young people's thinking and performance in school, improving their sleep and enabling…
- Trial name
- EPIC2 (NCT03150784)
- Testing
- EPIC Club
- Where
- 5 sites in United Kingdom
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Oxford Brookes University
ADHD, Narcolepsy
Pilot Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Abuse Liability of an Abuse-Deterrent Immediate-Release Formulation (ADAIR)
This is a pilot randomized, double-blind, active-controlled, 2-treatment, crossover study to evaluate the PK, user experience and abuse liability of manipulated ADAIR compared to a manipulated commercially-available d-amphetamine…
- Trial name
- NCT04232644
- Testing
- ADAIR 10mg IR capsules, Crushed d-amphetamine sulfate IR tablets
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Vallon Pharmaceuticals, Inc.
Specific Language Impairment
Specific Language Impairment (SLI) in Children May Caused by Epileptic Brain Activity
The objective of this study was to find if there is a possible association and the impact of epilepsy and epileptiform activity in children with SLI.
- Trial name
- NCT04141332
- Testing
- EEG was recorded by EEG Machines
- Where
- Egypt
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Mansoura University Hospital
Naltrexone, Methylphenidate Abuse
Study for Naltrexone on the Abuse Potential of Methylphenidate
The current abuse liability study aims to assess the potential for co-administration of naltrexone (NTX) to reduce the abuse potential of methylphenidate (MPH).
- Trial name
- NCT03769064
- Testing
- Methylphenidate 60 mg, Treatment Phase Sequence 4213, Treatment Phase Sequence 2134
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Avekshan LLC
Attention Deficit Hyperactivity Disorder
Sleep Extension and Behavior of Young Children
This pseudo-randomized intervention study examined change in inhibitory control following a sleep manipulation in which children with and without ADHD were instructed to advance their bedtime by 90 minutes for five days.
- Trial name
- NCT03446716
- Testing
- Sleep Extension
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Amherst
Child Development Disorders, Pervasive, Problems Psychosocial
Effect of Problem-Solving Training
The aim of this study, therefore, is to determine the effect of problem-solving training on the interpersonal problem-solving skills of mothers with special needs children. This study was a parallel randomized controlled trial.
- Conditions
- Child Development Disorders, Pervasive, Problems Psychosocial, Mother-Infant Interaction
- Trial name
- AtaturkU (NCT05688319)
- Testing
- Problem-Solving Training
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Autistic Disorder
Building Social Skills With Interdisciplinary Process Drama in ASD
This is a one group pre-post feasibility study of an interdisciplinary (theatre, Occupational Therapy (OT) and Speech Language Pathology (SLP)) intervention targeted at social skill development in children, aged 3-4.
- Trial name
- NCT03536351
- Testing
- Interdisciplinary process drama
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Utah
Autism Spectrum Disorder
Acupressure and Acupuncture as an Intervention With Children With Autism II
The purpose of this study is to see if children with autism spectrum disorder (ASD) will tolerate an acupressure and acupuncture intervention twice weekly over a 3 month period of time that targets regulatory and behavioral…
- Trial name
- NCT00935701
- Testing
- Acupressure and Acupuncture
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Autism Spectrum Disorder
Effects of Lactobacillus Plantarum PS128 in Children With ASD
Autism spectrum disorder (ASD) is a neurodevelopmental disorder that can cause significant social, communication and behavioral deficits. Probiotics are regarded as active microorganisms.
- Trial name
- NCT05307744
- Testing
- PS128
- Where
- Taiwan
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Autism Spectrum Disorder
Mindreading in Adults With Autism Spectrum Disorder
This study aims to investigate the ability of reading emotions by the Eyes task in adults with ASD, and examine the gazing pattern and frontal activation during the task.
- Trial name
- NCT04010409
- Testing
- no intervention
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
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