Clinical trials: Neurodevelopmental Disorder
Attention-Deficit/Hyperactivity Disorder
SNAP 25 Gene Study
To enhance our capacity to correctly choose the appropriate medication for ADHD patients on the first try based on the presence of a particular variant of a gene that could be identified on a laboratory test.
- Trial name
- NCT00885560
- Where
- Canada
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Attention Deficit Hyperactivity Disorder (ADHD), Sleep
Examination of the Dynamic Relationships of Sleep, Physical Activity, and Circadian Rhythmicity With Neurobehavioral Heterogeneity in ADHD
Attention deficit/hyperactivity disorder (ADHD) can present differently in individuals, with some individuals having difficulty with attentional control, hyperactivity, impulsivity, emotion dysregulation, and/or neurobehavioral…
- Conditions
- Attention Deficit Hyperactivity Disorder (ADHD), Sleep, Physical Activity
- Trial name
- NCT06810180
- Testing
- Go/No-Go Task, Delay discounting task, Mirror Tracing Persistence Task
- Where
- 2 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Williams Beuren Syndrome, Williams Syndrome
Characterization and Natural History of Williams Syndrome and Other Chromosome 7q11.23 Variants
The goal of this observational natural history study is to better characterize development, transition to adulthood, health and behavior of individuals diagnosed with Williams syndrome (WS) or carrying other variants of 7q11.23…
- Conditions
- Williams Beuren Syndrome, Williams Syndrome, Williams Beuren Region Duplication, Dup7
- Trial name
- NCT06930417
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
ADHD
Nocebo Education to Reduce the Potential Unintended Harms of Mental Health Awareness
This project has two aims. First, the research team will confirm whether providing a mental health awareness workshop poses unintended harms by raising the rate of self-diagnosis (as opposed to a neutral workshop) and causing…
- Trial name
- NCT06638411
- Testing
- ADHD information workshop, ADHD information workshop with nocebo education, Sleep workshop
- Where
- Canada
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Autism Spectrum Disorders
The Multi-Media Social Skills Project for Adults
This study is investigating the development of a social skills training program for adults with Asperger's Syndrome or high-functioning autism, ages 18 to 35 years. The Principal Investigator for this study is Dr.
- Trial name
- NCT02995564
- Testing
- social skills therapy
- Where
- United States
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Autism Spectrum Disorder, Autism
The Effect of Exercise Practices on Hyperactivity Levels in Children With Autism Spectrum Disorder
The aim of this study is to examine the effect of vestibular and proprioceptive exercise practices on the hyperactivity level in children with autism spectrum disorder.
- Trial name
- NCT06415539
- Testing
- classical physical therapy program, exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Uskudar University
Attention Deficit Hyperactivity Disorder, Problem Behavior
Stimulant Effects on Disruptive Behavior
The goal of this study is to determine the effects of stimulant medication on disruptive behavior, function, preference and choice; however, it is primarily methodological and will add to current research by establishing an…
- Trial name
- NCT03420339
- Testing
- Stimulant
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Matthew J O'Brien, PhD, BCBA-D
Autism Spectrum Disorder
The Effect of Digital Storytelling and Sensory Integration on Children With Autism
Given the interest of children with Autism Spectrum Disorder (ASD) in using computers, this study examined the effect of Digital Storytelling (DST) activity on increasing activity participation and self-regulation.
- Trial name
- NCT06491875
- Testing
- Digital Storytelling (DST), Sensory Integration Therapy (SIT)
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Biruni University
Autism Spectrum Disorder, Insomnia
SweetDreams Sleep Study for Children With Autism
This proposal will acquire preliminary data on the feasibility and effectiveness of an innovative and scalable strategy for improving access to effective sleep health care for preschool-aged children with Autism Spectrum Disorder…
- Trial name
- NCT04452045
- Testing
- SweetDreams
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Attention Deficit Hyperactivity Disorder
Magnetic Resonance Imaging of Brain Development in Attention Deficit Hyperactivity Disorder
The primary purpose of this study is to investigate brain whether ADHD represents a disruption or a delay of brain development. Children and adolescents both with and without ADHD are asked to participate in several MRI sessions…
- Trial name
- NCT00143767
- Where
- Netherlands
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Attention-deficit/Hyperactivity Disorder
Gut Microbiome and Serum Metabolome Alterations in ADHD Patients
Host-microbe interactions play a key role in brain development and function and in the etiology of neurodevelopmental disorders.
- Trial name
- ADHD (NCT03447223)
- Where
- China
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Fetal Alcohol Syndrome, Alcohol-related Neurodevelopmental Disorder
Neurocognitive Habilitation for Children With Fetal Alcohol Syndrome (FAS)/Alcohol-Related Neurodevelopmental Disorder (ARND)
Children will receive comprehensive evaluations through the Children's Research Triangle (CRT) clinical program. The assessment for the child will be in accordance with the protocol developed by Astley and Clarren as performed by…
- Trial name
- NCT00164346
- Testing
- neurocognitive habilitation
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Autistic Spectrum Disorders
A Pilot Trial of a Developmental, Individual-Difference, Relationship-Bases (DIR)/Floortime for Children With Autistic Spectrum Disorders
Thirty two children age 2-6 years are recruited into the study and the randomization will be stratified for chronological age and symptom severity into 2 main groups, intervention and control.
- Trial name
- DIR (NCT00954083)
- Testing
- DIR/Floortime, Routine care
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Voice, Speech
Virtual Reality as a Tool for Training Public Speaking Skills in Higher Education Students
According to the scientific literature, public speaking (PS) is an important skill for students to master. However, a large proportion of students do not feel comfortable speaking in public.
- Conditions
- Voice, Speech, Virtual Reality Simulation, Healthy Adult
- Trial name
- NCT07392554
- Testing
- Indirect Method, Direct Method
- Where
- Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Liege
Autism Spectrum Disorder, Parental Stress
The Effect of a Micro-Appreciation Intervention (Three-Things Journal Application) on Caregiver Burden, Family Functioning, and Happiness Levels for Mothers of Children With Autism Spectrum Disorder
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder in which individuals experience significant difficulties in social interaction, communication, and repetitive behaviors.
- Trial name
- NCT07124091
- Testing
- Positive Event Writing Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Movement Disorder
Cerebral Activity Related to Primary Motor Stereotypies in Children: An EEG Study.
Background: Motor stereotypies are a movement disorder characterized by involuntary, repetitive, and rhythmic movements. These movements have a predictable pattern and seem purposeful, but they serve no obvious function, tend to…
- Trial name
- NCT01037361
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Attention Deficit Hyperactivity Disorder
A Controlled Study of Solriamfetol for Attention Deficit Hyperactivity Disorder (ADHD) in Adults
A double-blind, placebo controlled study of solriamfetol for adults age 18 to 65 with diagnosis of Attention Deficit Hyperactivity Disorder.
- Trial name
- NCT04839562
- Testing
- Solriamfetol 75 MG, Solriamfetol 150 MG
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Autism Spectrum Disorder
A Study to Investigate the Effect of Esomeprazole and the Effect of Food on the Pharmacokinetics of Balovaptan in Healthy Volunteers
This study will investigate the effect of food and the effect of esomeprazole on the pharmacokinetics (PK) of a single dose of balovaptan in healthy volunteers.
- Trial name
- NCT04156646
- Testing
- Balovaptan, Esomeprazole
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Attention Deficit Hyperactivity Disorder
Neurophysiological Attention Test (NAT) for Objective Assessment of Adult ADHD
The purpose of this study is to refine a new assessment tool for Attention Deficit/Hyperactivity Disorder (ADHD) and then to test its validity (i.e. ability to discriminate between individuals with ADHD and healthy controls.
- Trial name
- NAT-II (NCT02756286)
- Testing
- NAT electroencephalography (EEG) test
- Where
- 3 sites in United States
- Volunteers
- 258 people, healthy volunteers welcome
- Sponsor
- Think Now Incorporated
ADHD, Attention Deficit Hyperactivity Disorder
Brain Plasticity Underlying Acquisition of New Organizational Skills in Children-R61 Phase
Organizational, time management and planning (OTMP) skills deficits are seriously impairing features of developmental disorders, such as Attention Deficit Hyperactive Disorder (ADHD) and autism, which compromise school…
- Conditions
- ADHD, Attention Deficit Hyperactivity Disorder, Neurodevelopmental Disorders
- Trial name
- NCT03148782
- Testing
- OST Intervention for participants with Organizational skill difficulties
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
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