Clinical trials: Neurodevelopmental Disorder
Neurodevelopmental Disorders
Motor Development Assessment and Support for Children With Neurodevelopmental Disorders
On the one hand, it helps to understand the motor development of preschool children, so as to provide early intervention means for the prevention of motor retardation and promote the healthy development of preschool children, and…
- Trial name
- CAMD-NDD (NCT07323004)
- Testing
- Characteristic Exercise Intervention, Traditional Rehabilitation
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aiyoudong Children and Youth Sports Health Research Institute
Autism Spectrum Disorder, Fra(X) Syndrome
Establishing a Diagnostic and Therapeutic Index in Autism Spectrum Disorder (ASD) and Fragile X Syndrome
The purpose of this study is to accumulate and quantitatively analyze data on the microbiome, serotonin signaling and genetics, and inflammatory cytokines from patients with Autism Spectrum Disorder and Fragile X Syndrome.
- Trial name
- NCT04869930
- Testing
- specimen collection
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Nova Mentis Life Science Corp
Attention Deficit Hyperactivity Disorder
Magnetic Resonance Imaging of Brain Development in Attention Deficit Hyperactivity Disorder
The primary purpose of this study is to investigate brain whether ADHD represents a disruption or a delay of brain development. Children and adolescents both with and without ADHD are asked to participate in several MRI sessions…
- Trial name
- NCT00143767
- Where
- Netherlands
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Behavior and Behavior Mechanisms
Translational Research to Inform Interventions for Challenging Behavior
This project is meant to identify relations between the reinforcement histories of 80 adults with intellectual and developmental disabilities (IDD) and the prevalence of extinction bursts.
- Trial name
- NCT04842500
- Testing
- Demand Informed Moderator Analysis
- Where
- 5 sites in United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Developmental Disabilities
Child Development and Genetic Biomarkers(II): Gene Verification and Data Integration
The aims of the study include (1) identifying genes associated with child development and developmental delay in Taiwan (2) comparing the differences and similarities between genetic biomarkers of development and developmental…
- Trial name
- NCT06532721
- Where
- Taiwan
- Volunteers
- 525 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Autism Spectrum Disorder
Measuring Brain Inflammation in Autism
Autism spectrum disorders (ASD) are highly disabling, persistent neurodevelopmental disorders. There are no available treatments for core symptoms of ASD or biologically-based clinical biomarkers.
- Trial name
- NCT03117530
- Testing
- Minocycline
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Autism Spectrum Disorder
Investigation of the HDAC4 Copy Number Variation and Its Effect on Gene and Protein Expression in Patients With ASD
Specific Aims of this study: 1. To understand the distribution of HDAC4 CNV in the families of the ASD patients with HDAC4 CNV; 2. To perform the analysis of gene expression; 3.
- Trial name
- NCT03670381
- Testing
- Psychiatric diagnosis
- Where
- Taiwan
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Autistic Disorder
Characterisation of Circadian Rhythm in Autistic Spectrum Disorder
Autism spectrum disorders (ASDs) are complex neurodevelopmental conditions characterized by deficits in social communication, delay in language and repetitive behaviors.
- Trial name
- NCT01984944
- Testing
- Autistic functional exploration, Control functional exploration
- Where
- France
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Autism Spectrum Disorder, Patient Engagement
Testing Design Thinking Methodology to Engage Hispanic and Latino Families of Autistic Children in Research.
The goal of this study is to compare two methods of engagement in research that include autistic individuals, Hispanic and Latino parents of autistic children, occupational therapy clinicians, teachers, and to use the information…
- Trial name
- NCT06111092
- Testing
- Design Thinking, Focus Groups
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Attention-deficit/Hyperactivity Disorder
A Genome-wide Association Study on the Endophenotype of Spatial Working Memory in ADHD
Specific Aims: 1. To find the genetic variations associated with spatial working memory performance in patients with ADHD by using genome-wide association studies (GWAS); 2.
- Trial name
- NCT02710929
- Where
- Taiwan
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Anxiety, Obsessive-Compulsive Disorder
Virtual Reality System for Anxiety and OCD
Cognitive Behavioral Therapy with fear provoking exposures is the most effective therapy for anxiety disorders. The investigators aim to enhance this therapy with the use of virtual reality exposures.
- Trial name
- NCT03636022
- Testing
- VR System, Control
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Minnesota HealthSolutions
Brain Diseases, Memory Disorders
Low Intensity Focused Ultrasound for Learning and Memory and Emotion Regulation
The goal of this clinical trial is to investigate the impact of low intensity focused ultrasound pulsation (LIFUP) to two different brain regions, the amygdala and entorhinal cortex, in older adults.
- Conditions
- Brain Diseases, Memory Disorders, Learning Disabilities, Cognitive Impairment
- Trial name
- LIFUPMEMEMOT (NCT03717922)
- Testing
- Low Intensity Focused Ultrasound Pulsation to Amygdala, Low Intensity Focused Ultrasound Pulsation to Entorhinal Cortex
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Epilepsy, Pregnancy
Maternal Outcomes and Neurodevelopmental Effects of Antiepileptic Drugs (MONEAD)
Epilepsy is one of the most common neurological disorders affecting women of childbearing age. Poor pregnancy outcomes are increased in these women and their children.
- Trial name
- MONEAD (NCT01730170)
- Where
- 20 sites in United States
- Volunteers
- 565 people, healthy volunteers welcome
- Sponsor
- Stanford University
Attention Deficit-Hyperactivity Disorder
Influence of Stimulant Medication on Brain Processes for Decision Making in Attention Deficit Hyperactivity Disorder
The goal of this trial is to investigate the cognitive- and brain-mechanisms underlying decision making (DM) and learning in young adults with Attention-Deficit/Hyperactivity Disorder (ADHD) as well as the modulation of…
- Trial name
- NCT01831622
- Testing
- Ritalin
- Where
- 2 sites in Norway
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Mats Fredriksen
Autism Spectrum Disorder
The Effect of Individualised Homoeopathic Treatment of Autism Spectrum Disorder in Children
The aim of this study is to determine the effect of individualised homoeopathic treatment of children with Autism Spectrum Disorder (ASD).This study is of descriptive case study design, with a structured interview and…
- Trial name
- NCT02363673
- Testing
- Individualised homoeopathic remedy in aqua distilla
- Where
- South Africa
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Johannesburg
Autism Spectrum Disorder
Adapted Judo for Children With Autistic Spectrum Disorders
The project is aligned with one of the overall: To promote social inclusion and equal opportunities, encouraging participation in sport and physical activity.
- Trial name
- AUTJUDO (NCT04523805)
- Testing
- Adapted judo programme
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Ramon Llull
Autism Spectrum Disorder
Evaluation of Skillflix for Parents of Youth With ASD
The goal of this clinical trial is to evaluate the effectiveness of using a Microskills video training library for training parents of adolescents with ASD in talking with their teens about relationships and sexual health topics.
- Trial name
- NCT05958394
- Testing
- SkillFlix for Parents
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ashley Philliber
Autism Spectrum Disorder
The Effect of Simulation-based Training on Confidence and Competence in Obtaining Vitals in a Child With Autism
The objective is to evaluate the efficacy of an online learning module combined with high fidelity simulation-based training in improving medical assistants' and registered nurses' self-confidence and competence scores in taking…
- Trial name
- NCT05288868
- Testing
- Educational Intervention: online didactic lecture and educational simulation activity
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Cerebral Palsy, Developmental Delay
SmarToyGym: Smart Detection of Atypical Toy-oriented Actions in At-risk Infants
The study aims to develop a SmarToyGym where sensitized, wireless toys are strategically hung and placed within reach of infants to elicit toy-oriented body and arm/hand movements.
- Conditions
- Cerebral Palsy, Developmental Delay, Stroke, Fine Motor Delay
- Trial name
- NCT02813889
- Testing
- SmarToyGym
- Where
- 2 sites in United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Brain Activity
Brain Activity by Magnetoencephalography for Children
Investigate the differences in activation of brain networks during performing functional tasks for children with attention deficit hyperactivity disorder with developmental delays and typical development
- Trial name
- NCT04629482
- Testing
- Brain networks activity
- Where
- Taiwan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
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