Clinical trials: Neurodevelopmental Disorder
Autism Spectrum Disorder
Early, Objective Detection of Autism.
1- To test the hypothesis that using the SensoDetect Brainstem Evoked Response Audiometry (BERA) technology may be an effective support tool for pediatricians to detect autism.
- Trial name
- NCT06447285
- Testing
- SensoDetect BERA technology
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- SensoDetect
ADHD, Controls
Validating a New Non-invasive Approach to Testing Lidocaine Effectiveness
This work will assess the reliability of a simple painless test for the effectiveness of the commonly used local anesthetic lidocaine
- Trial name
- NCT03680885
- Testing
- Lidocaine gel, Injected lidocaine
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- PhenoSolve, LLC
Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder
SKOLKONTAKT - Social Skills Training in a School Setting
The study investigates the behavioral effects of an adapted manual-based social skills training program (SKOLKONTAKT) for the mainstream education plan delivered by school personnel, with pupils (15-20 years) with…
- Conditions
- Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder, Anxiety, Depression
- Trial name
- SKOLKONTAKT (NCT04302818)
- Testing
- SKOLKONTAKT, Social activity group
- Where
- Sweden
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Autism Spectrum Disorder
Impact of Early Interventions on Neurocognitive Profile of Children With Autism Spectrum Disorder
The Early start Denver model (Rogers, 2010; Dawson, 2010) is a developmental and behavioral model that aim to enhance socio-comunicative abilities and also global development of children with Autism spectrum disorder (ASD).
- Trial name
- IDEAEYE (NCT03254264)
- Testing
- Early Start Denver Model, 'as-usual' intervention
- Where
- France
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Oppositional Defiant Disorder, Conduct Disorder
Multi-Family Group Therapy for Reducing Behavioral Difficulties in Youth
This study will examine the effectiveness of a multiple family group mental health service delivery strategy in improving mental health service use and outcome for urban, low income children of color, ages 7-11 years old with…
- Trial name
- NCT00404911
- Testing
- MFG therapy, Standard of Care
- Where
- United States
- Volunteers
- 416 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Velopharyngeal Insufficiency, Swallowing
Velopharyngeal Insufficiency After Maxillomandibular Advancement Osteotomy in Obstructive Sleep Apnea Patients
The aim of this study is to gain insight into the development of velopharyngeal insufficiency (VPI) in patients who have undergone maxillomandibular advancement osteotomy (MMA) as a treatment for obstructive sleep apnea syndrome…
- Conditions
- Velopharyngeal Insufficiency, Swallowing, Nasality, Speech
- Trial name
- VPIMMA (NCT07301021)
- Where
- Netherlands
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Cerebral Palsy, Hemiplegic, Sensory Processing Disorder
Sensory Processing, Postural Stability, and Selective Motor Control in Children With Hemiplegia
The goal of this observational case-control study is to examine the relationship between sensory processing abilities, postural stability, and selective motor control (SMC) in children aged 6-10 years with hemiplegic cerebral…
- Conditions
- Cerebral Palsy, Hemiplegic, Sensory Processing Disorder, Postural Balance, Motor Skills Disorders
- Trial name
- HeSPoM (NCT06989034)
- Testing
- Child Sensory Profile 2 (SP2) for Sensory processing abilities, HUMAC Balance System for Postural stability evaluation, Selective Motor Control Evaluation for the upper and lower extremities
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Attention Deficit and Disruptive Behavior Disorders, Child Behavior Disorders
Study of Children at Risk for Disruptive Behavior Disorders
A conduct disorder is characterized by repetitive and persistent patterns of behavior where the basic rights of others and rules are violated.
- Conditions
- Attention Deficit and Disruptive Behavior Disorders, Child Behavior Disorders, Passive-Aggressive Personality Disorder
- Trial name
- NCT00001233
- Where
- United States
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
ADHD - Attention Deficit Disorder With Hyperactivity
Clinical Study of Non-invasive 40-Hz Audiovisual Stimulation Guided by Gamma EEG Monitoring for Promoting Perioperative Brain Function Recovery in Children
Exposure to general anesthesia during early brain development has emerged as an important risk factor for long-term attention-deficit/hyperactivity disorder (ADHD)-like behaviors and learning difficulties in school-aged children.
- Trial name
- NCT07719465
- Testing
- 40-Hz non-invasive synchronized audiovisual stimulation
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- General Hospital of Ningxia Medical University
ADHD, ADD
ADHD Electrophysiological Subtypes and Implications in Transcranial Direct-current Stimulation
In the present study the aim is to examine whether transcranial direct-current stimulation (tDCS) generated excitability changes and induce modifications of functional cortical architecture in Attention Deficit Hyperactivity…
- Trial name
- tdcs&adhd (NCT01649232)
- Testing
- Active tDCS
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Spanish Foundation for Neurometrics Development
ADD, ADHD
Neurocognitive and Neurobiological Improvement in ADHD Children With High Protein Diet
Multicenter, Prospective, randomized, comparative and controlled study about the beneficial effects in behavior and brain connectivity of different dietary patterns in 100 children with ADHD between 7 and 12 years, followed up…
- Trial name
- BrainProtein (NCT02614599)
- Testing
- BP22042013, Low carbohydrate diet
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Spanish Foundation for Neurometrics Development
Autism Spectrum Disorder, Autism
Achieving Steady Work Among Adults With Autism Through Specialized Employment Program
Individuals with autism spectrum disorder (ASD) have significantly higher levels of unemployment and underemployment compared to their typically developing peers and all other groups with neurodevelopmental disorders, even though…
- Trial name
- NCT04107064
- Testing
- NaW, NaW-DS
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Lawrence Fung
Child Development, Infant Development
Expanding the Infant Achievements Intervention Through Community Partnerships
The goal of the research study is to increase teachers' implementation of evidence-based practices in Early Head Start classrooms through the delivery of a professional development (PD) training intervention.
- Conditions
- Child Development, Infant Development, Developmental Delay, Language Development
- Trial name
- NCT06312358
- Testing
- Building Capacity for Infant Achievements in Child Care
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Refractive Error, Visual Impairment
The Baltimore Reading and Eye Disease Study
The Baltimore Reading and Eye Disease Study (BREDS) is a two year study to determine the prevalence of vision problems in an early school age population with reading difficulty.
- Conditions
- Refractive Error, Visual Impairment, Convergence Insufficiency, Reading Disabilities
- Trial name
- BREDS (NCT02607384)
- Testing
- Eyeglass wearing, Orthoptic exercises, Specialist referral
- Volunteers
- 328 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Parent-Child Relations, Meals
Parent-Mediated Intervention for Families With Children With Autism and Feeding Challenges, Australia Cohort
The goal is to expand a parent-mediated intervention for feeding challenges in children with autism with an Australian cohort, building on recent research and current successful models already being used.
- Conditions
- Parent-Child Relations, Meals, Autism Spectrum Disorder
- Trial name
- NCT05852548
- Testing
- Parent-Mediated Intervention
- Where
- Australia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
ADHD
Effects of Noise Cancelling Headphones on Neurocognitive and Academic Outcomes in ADHD
The purpose of this study is to evaluate performance on the Attention Deficit Hyperactivity Disorder ( ADHD) Battery of the Cambridge Automated Neuropsychological Test Battery (CANTAB), including spatial working memory…
- Trial name
- NCT03216512
- Testing
- Use of Noise Cancelling Headphones
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Duke University
Autism Spectrum Disorder
Training and Implementation of RUBI in Community Mental Health Settings
This project is focused on evaluating outcomes related to this statewide clinical training effort in the RUBI parent training program.
- Trial name
- NCT05742464
- Testing
- RUBI
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Autism Spectrum Disorder
Insecure Attachment and Psychosocial Functioning in Autistic Adults Are Mediated by Depression and Paranoid Ideation
The present study examines if depressive symptoms, paranoid ideation, and emotion regulation strategies mediate the relationship between attachment and psychosocial functioning in autistic adults.
- Trial name
- NCT06030167
- Testing
- Insecure attachment and psychosocial functioning in autistic adults
- Where
- Netherlands
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Parnassia Groep
Tourette Syndrome
Impulsivity in Tourette Syndrome : Behavioral and Neuroimaging Study
Tourette syndrome (TS) is characterized by the presence of multiple vocal and motor tics. Behavioral disorders associated with TS are common, particularly impulsivity, anti-sociality and socially inappropriate behavior.
- Trial name
- COGIT (NCT02960698)
- Testing
- IRM and comportemental tasks
- Where
- France
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
ADHD - Attention Deficit Disorder With Hyperactivity
Sustained Endogenous Attention Deficits in Attention Deficit Hyperactivity Disorder
Subjects with ADHD may exhibit deficits in sustained internal attention. The "Sustained-Paced Finger Tapping" test was recently developed and experimentally used in international literature to assess sustained internal attention…
- Trial name
- NCT06900400
- Testing
- Sustained-Paced Finger Tapping" (Petilli et al., 2018)
- Where
- 2 sites in Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
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