Clinical trials: Neurodevelopmental Disorder (Diagnosis)
ADHD
The Relationship Between CES1 Genotype and Methylphenidate Response in Children With ADHD - INDICES Work Package 6
This is a prospective observational study of a cohort of children diagnosed with Attention Deficit Hyperactive Disorder (ADHD) and followed with weekly assessments during the first 12 weeks of Methylphenidate (MPH) treatment, and…
- Trial name
- NCT04366609
- Testing
- Methylphenidate
- Volunteers
- 207 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Autism
A Study of Oxytocin in Children and Adolescents With Autistic Disorder
The investigators propose to conduct this pilot study to evaluate oxytocin as a supplemental treatment for improving social difficulties in individuals with autism.
- Trial name
- Oxytocin (NCT01308749)
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of North Carolina, Chapel Hill
Tourette Syndrome
Thalamic Deep Brain Stimulation for the Treatment of Refractory Tourette Syndrome
This research is being performed to try to understand if the use of deep brain stimulation or DBS can treat the symptoms of Tourette syndrome that do not respond well to current medications.
- Trial name
- NCT01817517
- Testing
- Medtronic Activa Deep Brain Stimulation System
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Johns Hopkins University
Ischemic-Hypoxic Encephalopathy
Long Term Prognostic of Neonatal Hypoxic Ischemic Encephalopathy With Hypothermia Treatment
The primary objective is to evaluate neonatal characteristics, and biological and clinical investigations as predictive factors of death, or of severe and moderate neurodevelopmental disability at 3 years, in a large…
- Trial name
- LyTONEPAL (NCT02676063)
- Where
- 22 sites in France
- Volunteers
- 800 people
- Sponsor
- University Hospital, Grenoble
Adhd
Improving Emotion Regulation in Adolescents With ADHD
The purpose of our study is to examine the impact of a program that provides emotion regulation skills for adolescents aged 11-16 with Attention-Deficit/Hyperactivity Disorder (ADHD) and poor emotion regulation.
- Trial name
- NCT03733548
- Testing
- RELAX
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Virginia Commonwealth University
Attention Deficit Hyperactivity Disorder
A Randomized Controlled Study of Medical-education-community Collaborated Intervention in Children With ADHD
This study is designed to test if the medical-education-community collaborated intervention can reduce the symptoms of children with Attention deficit hyperactivity disorder (ADHD) compared to routine clinical care.
- Trial name
- NCT04528433
- Testing
- Medical-education-community Collaborated Intervention, routine clinical care
- Sponsor
- Children's Hospital of Fudan University
ADHD
A Classroom Study to Assess the Time of Onset of Vyvanse (Lisdexamfetamine Dimesylate) in Pediatric Subjects Aged 6-12 With Attention Deficit/Hyperactivity Disorder (ADHD)
The primary objective of this study is to assess the time of onset of Vyvanse compared to placebo, in the analog classroom as measured by the Swanson, Kotkin, Agler, M.
- Trial name
- NCT00500149
- Testing
- Vyvanse (lisdexamfetamine dimesylate)
- Where
- 9 sites in United States
- Volunteers
- 129 people
- Sponsor
- Shire
Adhd
The Study of Efficacy and Safety of Generic Methylphenidate Prolong-released Comparison With Original
This study is a cross-over trial, design to determine the efficacy and safety of generic and original prolong-release methylphenidate (PR-MPH) in children with ADHD who had received immediate-release methylphenidate treatment
- Trial name
- NCT05410626
- Testing
- prolong-release methylphenidate
- Volunteers
- 78 people
- Sponsor
- Mahidol University
Autism Disorder
Triadic Interactions of Families With Autism and Oxytocin
The study will investigate the effects of an intranasal administration of oxytocin (OT) to parents of children with autism spectrum disorders (ASD) on the quality of mother-father-child interactions.
- Trial name
- TAO (NCT01912378)
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Physical Activity, Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse)
Expanded Game Squad for Neurodiverse Youth
The proposed study will pilot the use of an adapted Game Squad intervention aimed at improving physical activity and other important health behaviors (nutrition, sleep hygiene, screen time habits) for children and adolescents…
- Conditions
- Physical Activity, Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse), Health Behavior, Developmental Disorder
- Trial name
- NDGameSquad (NCT03665415)
- Testing
- NDGameSquad
- Where
- 2 sites in United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Merrimack College
Autism Spectrum Disorder, Parent-Child Relations
Parent Video Feedback Intervention Study
The purpose of this study is to use a randomized controlled trial to test the effectiveness of parent coaching sessions using video-based feedback, compared to the sessions without the use of video-based feedback on parent…
- Trial name
- NCT03397719
- Testing
- Treatment Condition, Control Group
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Weill Medical College of Cornell University
Autism Spectrum Disorder
Opt-In Early Pilot Study
Latinx and Rural-living children with diagnosed or suspected autism have especially long wait times for diagnoses and intervention, up to a year or even more.
- Trial name
- NCT06908187
- Testing
- Opt-In Early Latinx intervention, Opt-In Early Rural Intervention
- Where
- 2 sites in United States
- Volunteers
- 120 people
- Sponsor
- Oregon Health and Science University
Child Behavior Disorders, ASD
Improving Self-regulation in Children With Neurodevelopmental Disorders:
Children with neurodevelopmental disorders may show difficulties in self-regulation. The main objective of this study is to improve self-regulation skills in children between 6 and 11 years old with neurodevelopmental disorders.
- Conditions
- Child Behavior Disorders, ASD, ADHD
- Trial name
- NCT04418921
- Testing
- Self-regulation: MRehab - Un colegio emocionante, clinical trial with non-immersive virtual reality, Traditional self-regulation program
- Volunteers
- 42 people
- Sponsor
- Universidad de Granada
Autism Spectrum Disorder
STEPS: A Virtual Reality-based Intervention for Adults With Autism.
The goal of this clinical trial is to learn if a new Virtual Reality-based intervention will be effective in treating social cognitive challenges in adults with autism. The main questions it aims to answer are: 1.
- Trial name
- STEPS (NCT06438536)
- Testing
- Virtual Reality-based Social Cognitive Training
- Where
- Denmark
- Volunteers
- 140 people
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
Tourette Syndrome
Safety and Efficacy of Cannabis in Tourette Syndrome
For many individuals with Tourette syndrome (TS), available medications do not help with their symptoms, or cause significant side effects.
- Trial name
- NCT03247244
- Testing
- Cannabis
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- University Health Network, Toronto
Congenital Heart Defect, Executive Function
Improving Neurodevelopmental Outcomes in Children With Congenital Heart Disease: An Intervention Study
Each year, approximately 1 child in every 100 is born with Congenital Heart Disease (CHD), making it the most common birth defect.
- Conditions
- Congenital Heart Defect, Executive Function, Children, Neurodevelopmental Disorders
- Trial name
- NCT03023644
- Testing
- Cogmed Working Memory Training
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Boston Children's Hospital
Math Learning Disability, Child Development
Interventions in Mathematics and Cognitive Skills
The purpose of this study is to investigate neurocognitive mechanisms underlying response to intervention aimed at enhancing, and remediating weaknesses in, numerical skills in children, including those with mathematical learning…
- Conditions
- Math Learning Disability, Child Development, Developmental Disability, Learning Disabilities
- Trial name
- NCT05201534
- Testing
- Interventions in Mathematics and Cognitive Skills - Experimental, Interventions in Mathematics and Cognitive Skills - Active Comparator
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Stanford University
Autism
Study of Pharmacokinetics, Safety, Efficacy, and Tolerability of Memantine in Children With Autism
The purpose of this study is to investigate the safety and efficacy of memantine extended release, as well as its extent of absorption in pediatric patients with autism.
- Trial name
- NCT00872898
- Testing
- Memantine - Extended Release (ER)
- Where
- 17 sites in United States
- Volunteers
- 124 people
- Sponsor
- Forest Laboratories
Autism Spectrum Disorder (ASD)
Omega-3 Fatty Acids Monotherapy in Children and Adolescents With Autism Spectrum Disorders
The primary aim of this study is to examine the efficacy and tolerability of short-term omega-3 fatty acids monotherapy in youth with Autism Spectrum Disorders (ASD).
- Trial name
- NCT01248130
- Testing
- Omega-3 Fatty Acid
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Massachusetts General Hospital
Attention Deficit Hyperactivity Disorder
Development of Virtual Reality-based Interventions to Strengthen Cognitive Skillsets Related to Attention Deficit Hyperactivity Disorder (ADHD): A Pilot Phase I and Randomized Controlled Phase II Trial
Background: Children with attention deficit hyperactivity disorder (ADHD) often have cognitive problems. It may be hard for them to control their behaviors, concentrate for long periods, or make decisions.
- Trial name
- NCT05608434
- Testing
- Non-adaptive Floreo VR control, Floreo Virtual Reality application
- Where
- United States
- Volunteers
- 219 people
- Sponsor
- National Institute of Mental Health (NIMH)
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