Clinical trials: Neurodevelopmental Disorder (Diagnosis)
ADHD Predominantly Inattentive Type
Cognitive-Behavioral Therapy for Adults With Attention-Deficit/Hyperactivity Disorder Inattentive Presentation
Using a randomized controlled design, standard treatment of group cognitive-behavioral therapy (CBT) according to the Hesslinger protocol is compared to a newly developed group treatment specifically designed for adult patients…
- Trial name
- NCT04090983
- Testing
- Cognitive-behavioral therapy (Hesslinger protocol), Cognitive-behavioral therapy (CADDI protocol)
- Where
- Sweden
- Volunteers
- 108 people
- Sponsor
- Karolinska Institutet
Cerebral Palsy Infantile, Pre-Term
Motor-voice Assessment in Infants (MAMI)
The goal of this observational study is to discover features of normal and disordered motor-voice profiles that are biobehavioral markers of physical disability in infants..
- Conditions
- Cerebral Palsy Infantile, Pre-Term, Motor Delay, Neurodevelopmental Disorders
- Trial name
- MAMI (NCT06807203)
- Testing
- Behavioral observation
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Ohio State University
Developmental Delay
Bright by Three (BB3) Effectiveness Study
The Investigators propose to conduct a pragmatic randomized controlled trial of 350 one to four year old children and their caregivers to study the effectiveness of 1) the Bright By Three (BB3) intervention for promoting…
- Trial name
- NCT02717390
- Testing
- Bright By Three (BB3), Texts for Child Safety (TCS)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Autism Spectrum Disorder
Cognoa ASD Diagnosis Aid Validation Study
The primary objective of this study is to collect data to ascertain the Positive Predictive Value (PPV) and Negative Predictive Value (NPV) of the current version of the Cognoa diagnostic device.
- Trial name
- NCT04151290
- Testing
- Cognoa ASD diagnostic device
- Where
- 16 sites in United States
- Volunteers
- 711 people
- Sponsor
- Cognoa, Inc.
Dystonia, Drug Induced Dystonia
Clinical Validation of DystoniaNet Deep Learning Platform for Diagnosis of Isolated Dystonia
This research involves retrospective and prospective studies for clinical validation of a DystoniaNet deep learning platform for the diagnosis of isolated dystonia.
- Conditions
- Dystonia, Drug Induced Dystonia, Parkinson Disease, Essential Tremor
- Trial name
- NCT05317390
- Testing
- DystoniaNet-based diagnosis of isolated dystonia
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary
Autism
Improving Attention Skills of Children With Autism
Toddlers with autism have poor joint attention skills. Joint attention skills include pointing to objects, following another person's gaze, and responding to invitations to join in a social interaction.
- Trial name
- NCT00065910
- Testing
- Caregiver joint attention intervention
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Attention Deficit Hyperactivity Disorder
The Effects of Methylphenidate and Non-invasive Brain Stimulation on Inhibitory Control in Children With ADHD
The aim of this study is comparing the effects of non-pharmacological intervention (transcranial Direct Current Stimulation, tDCS) with those of drug (methylphenidate, MPH) administration in children and adolescents with ADHD.
- Trial name
- NCT04964427
- Testing
- Methylphenidate, anodal tDCS
- Where
- Italy
- Volunteers
- 26 people
- Sponsor
- Bambino Gesù Hospital and Research Institute
Attention Deficit Hyperactivity Disorder
Investigating the Effect of Vortioxetine in Adult ADHD Patients
The purpose is to determine the effect of vortioxetine treatment on ADHD symptoms in adult patients with ADHD in a 12 weeks study.
- Trial name
- NCT02327013
- Testing
- vortioxetine 10 mg tablet, vortioxetine 20 mg tablet
- Where
- 15 sites in United States
- Volunteers
- 227 people
- Sponsor
- H. Lundbeck A/S
Executive Function Deficits (EFD), Developmental Coordination Disorder
Let's CO-OPerate! Together we Are Stronger
The goal of this replicated single case experimental study using a randomized multiple baseline design across participants and goals is to enable children/adolescents (aged 8-16 years) with developmental coordination disorders…
- Conditions
- Executive Function Deficits (EFD), Developmental Coordination Disorder, Acquired Brain Injury (Including Stroke), Brain Injury, Fetus and Neonate
- Trial name
- NCT07085403
- Testing
- Cognitive Orientation to daily Occupational Performance (CO-OP) is a cognitive problem-solving approach
- Where
- France
- Volunteers
- 12 people
- Sponsor
- Hopitaux de Saint-Maurice
Autism Spectrum Disorder, Theta Burst Stimulation
Explore the Impacts of One Session and Multiple Session Theta Burst Stimulation Over Cerebellum in Adults With Autism Spectrum Disorder
This study aims to establish a personalized theta burst stimulation (TBS, an advanced variant of repetitive transcranial magnetic stimulation, rTMS) protocol considering autistic idiosyncrasy (interindividual variability).
- Trial name
- NCT07114770
- Testing
- Theta Burst Stimulation (TBS, an advanced variant of repetitive transcranial magnetic stimulation)
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Autism Spectrum Disorder (ASD), Anxiety
Adapted Group Therapy Compared With Usual Care for Anxiety and Depression in Adults With an Autism Diagnosis
The goal of this clinical trial is to learn whether an adapted group therapy works to treat anxiety and depression in adults with an autism diagnosis. The therapy is a form of cognitive behavioral therapy (CBT).
- Conditions
- Autism Spectrum Disorder (ASD), Anxiety, Depression
- Trial name
- CoMind (NCT07880028)
- Testing
- Autism-adapted group cognitive behavioral therapy
- Volunteers
- 154 people
- Sponsor
- Lovisenberg Diakonale Hospital
Attention Deficit and Disruptive Behavior Disorders, Attention Deficit Disorder With Hyperactivity
Effectiveness of the Quotient® ADHD Assessment in a System of Care
The study goal is to examine whether the use of an objective computerized neuroassessment (the Quotient System) for Attention-Deficit/Hyperactivity Disorder (ADHD) is related to improved outcomes among pediatric patients being…
- Trial name
- NCT02094612
- Testing
- Quotient®, Usual Clinic ADHD Care
- Where
- 3 sites in United States
- Volunteers
- 207 people
- Sponsor
- Kaiser Permanente
Neurodevelopmental Disorders, Congenital Cardiomyopathy
KIDSHEART AND BRAIN : Early EEG Surgery Congenital Heart Disease Predict Onset of Neurodevelopmental Disorders
Congenital cardiopathy are frequent malformations (1/100 birth). The progress of surgery permit a survival rate at the adult age of more than 90%.
- Trial name
- KHB (NCT05658965)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Lille
Down Syndrome
Effect of the Sensory Integration Approach on Balance and Motor Coordination in Children With Down Syndrome
Down syndrome can be characterized by global mental and physical dysfunction or isolated gait, cognition, growth, or sensory disturbances.
- Trial name
- NCT05583565
- Testing
- sensory integration approach, traditional physical therapy program
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Autism Spectrum Disorder
Family Centered Occupational Therapy on Play Skills and Participation of Children With ASD
Play skills and participation of children with Autism Spectrum Disorder (ASD) have been restricted by their core symptoms, resulting in heightened parenting stress and affected family daily life.
- Trial name
- NCT02795611
- Testing
- Family-centered occupational therapy, regular occupational therapy, intervention done outside our hospital
- Where
- Taiwan
- Volunteers
- 23 people
- Sponsor
- National Taiwan University Hospital
Autism With High Cognitive Abilities, COVID-19 Pandemic
The Impact of Covid-19 Pandemic On The Children With Autism Spectrum Disorder
The Covid-19 outbreak has caused families and individuals to change their life routines and eating habits, and has affected their psychology, especially for children with autism, due to the change in their routines.
- Trial name
- NCT05197634
- Testing
- Not Applicable (observation)
- Where
- Turkey (Türkiye)
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Attention Deficit Hyperactivity Disorder
Event Rate and Effects of Stimulants in ADHD
Stimulants alleviate information processing and task performance deficits in Attention Deficit/Hyperactivity Disorder (ADHD). Long acting formulations of amphetamines such as lisdexamphetamine dimesylate (LDX) are especially…
- Trial name
- ERESA (NCT01913912)
- Testing
- LDX., sugar pill, computer task (Go/No-Go task)
- Where
- 2 sites in Belgium
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Ghent
Intellectual Disability
Intensive Support Teams Study
About 17% of people with ID living in the community have challenging behaviour such as aggression to others or property, self-injury or hyperactivity.
- Trial name
- IST-ID (NCT03586375)
- Testing
- Intensive Support Team Care
- Where
- 16 sites in United Kingdom
- Volunteers
- 226 people
- Sponsor
- University College, London
Aphasia, Apraxia of Speech
Treatments of Acquired Apraxia of Speech
This study was designed to examine the effects of speech therapy on ability to produce speech sounds in persons with acquired apraxia of speech.
- Conditions
- Aphasia, Apraxia of Speech, Stroke
- Trial name
- Apraxia (NCT01483807)
- Testing
- Sound Production Treatment - Blocked, Sound Production Treatment - Random
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- VA Office of Research and Development
Autism Spectrum Disorder
Sibling-Mediated Intervention on Literacy and Reciprocity for Children With Autism
Given the increasing prevalence of autism spectrum disorder (ASD), estimated to be 1 in 68 in the United States alone, ASD has become one of the fastest-growing pediatric concerns.
- Trial name
- NCT05098392
- Testing
- Sibling-mediated intervention
- Where
- 3 sites in United States, China
- Volunteers
- 8 people
- Sponsor
- Arizona State University
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