Clinical trials: Neuroimaging
Healthy
NeuroCognitive Bases of Tool Use
Tool use is considered to be the hallmark of complex cognitive adaptations that humans have achieved trough evolution, that provides an adaptive advantage to the human species.
- Trial name
- TECHNITION (NCT04566744)
- Testing
- fRMI
- Where
- France
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Tinnitus
Neuro-Music Therapy for Recent Onset Tinnitus: Evaluation of a Therapy Concept
To date, the pharmacological treatment options for tinnitus are unsatisfactory. For acute tinnitus drug treatments are only rated as being successful in approximately half of all cases.
- Trial name
- NCT01566708
- Testing
- Neuro-Music Therapy immediately, Neuro-Music Therapy after waiting time, Music-therapeutical stress management coaching
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- German Center for Music Therapy Research
Attention Deficit Hyperactivity Disorder, ADHD
Imaging Stimulant and Non Stimulant Treatments for ADHD: A Network Based Approach
The growing number of medications used to treat attention-deficit/hyperactivity disorder (ADHD) raises important questions about whether different medications have similar or different therapeutic mechanisms of action.
- Trial name
- NCT01678209
- Testing
- fMRI scans, Atomoxetine arm, Methylphenidate arm
- Where
- United States
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Child Development
LCPUFA Supplementation: A Multi-Modality Imaging Study
The purpose of this study is to take images of the brain in order to see if long-chain polyunsaturated fatty acid (LCPUFA) exposure during infancy influences brain structure and function in middle childhood.
- Trial name
- NCT02076048
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Kathleen Gustafson, Ph.D.
Nicotine Dependence
Multimodal Neuroimaging Genetic Biomarkers of Nicotine AddictionSeverity
Background: Smoking is a difficult habit to quit, and some people find it more difficult to quit than others do. Nicotine is the substance in cigarettes that makes smoking so addictive.
- Trial name
- NCT01867411
- Where
- United States
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Spastic Cerebral Palsy, Acquired Brain Injury
Evaluation of Macroscopic Muscle Growth in Infants and Young Children With Spastic Cerebral Palsy
A mixed longitudinal design study will be carried out to explore the onset and time course of morphological muscle changes on a macroscopic level in children with spastic cerebral palsy (SCP).
- Trial name
- 3D-MMAP (NCT05197764)
- Where
- Belgium
- Volunteers
- 229 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Stroke, Acute, Stroke, Subacute
Bimanual Motor Skill Learning in Acute Stroke
The subacute phase of stroke provides a window into how a lesion perturbs sensorimotor functions prior to reorganisation driven by plasticity and neurorehabilitation.
- Trial name
- MLAS4 (NCT05760846)
- Testing
- REAplan®, Dextrain Manipulandum®
- Where
- 2 sites in Belgium
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University Hospital of Mont-Godinne
Postpartum Depression, Major Depressive Disorder
Neuropsychobiological Correlates of Sex-steroid Hormone Manipulation in Healthy Women: a Risk Model for Depression
The project aimed at identifying neuropsychobiological signatures of pharmacological sex-steroid hormone manipulations in healthy women as a risk model for depression.
- Conditions
- Postpartum Depression, Major Depressive Disorder, Postpartum Psychosis, Menopause
- Trial name
- GnRHa (NCT02661789)
- Testing
- Goserelin 3.6 mg implant
- Where
- Denmark
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Gitte Moos Knudsen
Bipolar Disorder, Frontotemporal Dementia, Behavioral Variant
A Study of the Behavioral Variant of Frontotemporal Dementia and Bipolar Disorder: a Neuroimaging and Epigenetics Integrated Approach
The aim of this study is to investigate the selective epigenetic modifications and their effect on brain's morphology and functionality in the frontotemporal dementia behavioral variant and bipolar disorder.
- Trial name
- DISBAND (NCT06706687)
- Testing
- DISBAND protocol
- Where
- Italy
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Schizophrenia, Psychosis
Neuroimaging Studies of Neurophysiological Phenotypes in Schizophrenia
Background: Eye tracking, the ability to focus on and follow a moving target with the eyes, is often difficult for people who have schizophrenia.
- Trial name
- NCT01036568
- Where
- 2 sites in United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Suicidal Behavior
Functional Neuroimaging and Genetic Vulnerability to Suicidal Behavior
The main objective is to highlight, by functional imaging (MRI) dysfunctional brain regions associated with vulnerability to suicidal behavior.
- Trial name
- NCT02960191
- Testing
- Magnetic resonance imaging (MRI)
- Where
- France
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Autobiographical Memory, Function of the Human Hippocampus
fMRI Studies of Memory and Perception
Episodic memory allows us to project ourselves back in time to mentally re-experience the past in vivid detail. This remarkable feat helps to define our personal identities and enables context-appropriate predictions that guide…
- Trial name
- NCT07860281
- Testing
- Participants use a smartphone to replay self-generated autobiographical memory cues.
- Where
- United States
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Florida State University
Major Depressive Disorder, Depression
Brain Imaging of rTMS Treatment for Depression
The overarching goal of this research program is to elucidate causal and directional neural network- level abnormalities in depression, and how they are modulated by an individually-tailored, circuit-directed intervention.
- Trial name
- NCT01829165
- Testing
- rTMS Treatment
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Stanford University
Seizure Disorder, Seizure Disorder, Post Traumatic
Neuroimaging Biomarker for Seizures
This multi-site study will examine patients with epilepsy (ES) following head injury [i.e., posttraumatic epilepsy (PTE)] and posttraumatic psychogenic Non-epileptic seizures (PNES) and will compare them to patients with…
- Conditions
- Seizure Disorder, Seizure Disorder, Post Traumatic, Traumatic Brain Injury, Non-Epileptic Seizure
- Trial name
- NIBMSZS (NCT03441867)
- Testing
- Cognitive Behavioral Therapy for Seizures, Standard Medical Care
- Where
- 3 sites in United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Providence VA Medical Center
Primary Cervical Dystonia, DYT 1 Dystonia
Neuroimaging of Dystonia
The main purpose of this study is to investigate primary cervical dystonia as compared to healthy control subjects and DYT 1 dystonia as compared to healthy control subjects by examining cognitive measures, physical measures, and…
- Trial name
- NID (NCT02046447)
- Testing
- Primary Cervical Dystonia (Trihexyphenidyl), Controls Primary Cervical Dystonia (Trihexyphenidyl), DYT 1 Dystonia (Healthy Control)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Florida
Magnetic Resonance
Test-retest Stability of MR-parameters. A Neuroimaging Pilot-study in Healthy Volunteers
Aim: To study the stability of brain MR-scanning parameters (blood-flow, microstructure, volume, metabolism) over 1 week in health volunteers. Hypothesis: MR-scanning parameters are stable over 1 week in healthy volunteers
- Trial name
- NCT01239615
- Where
- Denmark
- Volunteers
- healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Autism Spectrum Disorders
Brain Imaging Study of Adults With Autism Spectrum Disorders
This research study investigates the effects of oxytocin and vasopressin on brain activity in adults with Autism Spectrum Disorders using functional magnetic resonance imaging (fMRI).
- Trial name
- NCT01093768
- Testing
- Oxytocin, Vasopressin
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Intracerebral Hemorrhage
Chinese Multicenter Cohort Study of Intracerebral Hemorrhage
Spontaneous intracerebral hemorrhage is a severe form of stroke associated with high mortality and long-term disability. The Chinese Multicenter Cohort Study of Intracerebral Hemorrhage (CASA) is a prospective observational…
- Trial name
- CMCS-ICH (NCT07833410)
- Where
- China
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- Xiangya Hospital of Central South University
Transient Global Amnesia (TGA)
Neuropsycholgy and Neuroimaging in Transient Global Amnesia
The purpose of this study is to establish a diagnosis in transient global amnesia (TGA) in assessing three episodic memory's abilities (mental simulation throught the future, and the past, the learning of personnal actions i-e…
- Trial name
- 2NIA (NCT02562560)
- Testing
- Neuropsychological tests, Cerebral imaging (MRI, PET-FDG)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Mental Disorders, Healthy Control
Psychiatric Multi-omics and Neuroimaging Project
This study focuses on the structure and function of the brain and gene expression in peripheral blood of patients with schizophrenia, to explore the interaction and influence between the three.
- Trial name
- PMNP (NCT06580860)
- Testing
- Antipsychotic drugs, antidepressants, mood stabilizers, and sleep aids
- Where
- China
- Volunteers
- 1,899 people, healthy volunteers welcome
- Sponsor
- mingjun Zhong