Clinical trials: Neurologic Ambulation Disorder
Spinal Muscular Atrophy Type 3, Duchenne Muscular Dystrophy
Wearable Technology to Assess Gait Function in SMA and DMD
The purpose of this project is to devise instrumented insoles capable of accurately measuring gait at each footfall, over multiple hours in any environment.
- Trial name
- NCT04193085
- Testing
- Observational
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Columbia University
Aging, Age-Related Memory Disorders
Effects of Blueberry on Cognition and Mobility in Older Adults
This study is being conducted to assess the effect of dietary blueberry supplementation on cognition and mobility in older adults.
- Trial name
- NCT01888848
- Testing
- Freeze-dried Blueberry
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- USDA Human Nutrition Research Center on Aging
Aging, Parkinson Disease
Beam Walking Across the Lifespan for Falls Prediction
Background: Dynamic balance keeps the vertical projection of the center of mass within the base of support while the center of mass moves. The age-related decrease in dynamic balance is a risk factor for falls.
- Conditions
- Aging, Parkinson Disease, Stroke, Dementia
- Trial name
- BEAM (NCT03532984)
- Testing
- Beam test to predict falls
- Where
- 5 sites in Brazil, Germany and 3 more
- Volunteers
- 432 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Fatigue, Walking, Difficulty
Neurophysiological Effects of Transcutaneous Electrical Nerve Stimulation in Persons With MS
Transcutaneous Electrical Nerve Stimulation (TENS) is a treatment that could potentially reduce walking problems and fatigue in persons with Multiple Sclerosis.
- Conditions
- Fatigue, Walking, Difficulty, Multiple Sclerosis
- Trial name
- NCT06432686
- Testing
- Transcutaneous Electrical Nerve Stimulation, Movement
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Cerebral Palsy (CP), Typically Developing Children
The Effect of Perturbation Training on Reactive Balance in Children With Cerebral Palsy
The aim of this project was to evaluate whether perturbation training influences reflex modulation in children with spastic CP and whether changed reflex modulation leads to improved reactive balance and walking.
- Trial name
- NCT07818928
- Testing
- Balance training on a moving platform
- Where
- Belgium
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Spinal Cord Injuries, Stroke
Restorative Neuromodulation for Lower Extremity Functions
The overall objective of the proposed study is to restore lower-extremity functions of paraplegic individuals. Paralysis following Stroke or spinal cord injury (SCI) result harsh sufferings including lifelong dependence on…
- Conditions
- Spinal Cord Injuries, Stroke, Paralysis
- Trial name
- NCT04171375
- Testing
- trans-spinal Electrical Stimulation (tsES)
- Where
- Hong Kong
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Bone Resorption
The Novel Unloading Device "HEPHAISTOS" and Its Effects Upon Bone, Muscle and Vasculature
The present study aimed to investigate the importance of gravitational induced forces that appear during normal ambulation for the health of muscles, bones and blood vessels.
- Trial name
- HEP (NCT01576081)
- Testing
- HEPHAISTOS
- Where
- Germany
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- DLR German Aerospace Center
Difficulty Walking, Gait, Stumbling
Gait Analyses After Resurfacing Hip Arthroplasty Versus Metal on Metal Total Hip Arthroplasty, an Exploratory Study
Total hip replacement surgery is a very successful operation with good long-term results. Hip resurfacing arthroplasty is offered as a treatment option for young and active patients with osteoarthritis of the hip.
- Trial name
- NCT02484781
- Testing
- Gait analysis on a trendmill
- Where
- Netherlands
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Rijnstate Hospital
Parkinson Disease
Changes in Metabolic Activity, and Gait Function by Dual-task Cognitive Game-based Treadmill Intervention in Parkinson's Disease.
The present proposal will evaluate the neural underpinnings of (a) the decline of mobility function in Parkinson's disease (PD), and (b) the effects of an innovative computer-guided dual-task (DT) mobility training platform…
- Trial name
- CMAGDT (NCT04415775)
- Testing
- Game based treadmill Program, Conventional Gait Rehabilitation
- Where
- Canada
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Knee Osteoarthritis
Retro-walking in Knee Osteoarthritis
In osteoarthritis the most affected joint is knee due to degenerative changes. Degenerative changes cause age-related wear-and-tear and may be accelerated by injury, health and lifestyle factors, and possibly by genetic…
- Trial name
- NCT04546659
- Testing
- Retrowalking, Conventional Therapy
- Where
- Pakistan
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Gait, Unsteady
Virtual Reality Training for Walking Improvement in the Elderly
Safe walking needs the older adult to anticipate and respond quickly to external demands and sudden environmental changes. The practice of complex and challenging situations of the usual daily walking is very important to prevent…
- Trial name
- NCT05623462
- Testing
- The C-Mill virtual reality treadmill, Conventional Physical Therapy Program
- Where
- Saudi Arabia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Umm Al-Qura University
Neuromuscular Diseases
Controlled Study of Upper and Lower Limb Movements in Patients Patients with Pathologies That Have an Impact on Ambulation or Motor Function
The main aim of the study is to validate the algorithms developed to analyze the signals from the various sensors contained in the magneto-inertial control units and reconstruct upper and lower limb movements under different…
- Trial name
- NCT06439823
- Testing
- ActiMyo®/Syde®
- Where
- Belgium
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Laurent Servais
Stroke, Physical Therapy Modalities
Is the 6-Minute Walking Test Combined With an IMU Useful in Stroke Rehabilitation Assessment?
This Observational study aims at the evaluation of stroke subjects with an inertial measurement unit (IMU) during the execution of a 6-Minute Walking test, to evaluate the associations between the kinematic parameters retrieved…
- Conditions
- Stroke, Physical Therapy Modalities, Gait Analysis
- Trial name
- NCT04529642
- Testing
- Inertial Measurement Unit evaluation
- Where
- Italy
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Multiple Sclerosis, 3D Gait Analysis
Gait Analysis in Multiple Sclerosis Patients
In the literature, the results of vestibular rehabilitation treatment applied in patients with Multiple Sclerosis (MS) have been investigated in detail under the headings such as fatigue, physical activity level, and quality of…
- Conditions
- Multiple Sclerosis, 3D Gait Analysis, Vestibular Rehabilitation
- Trial name
- NCT05299151
- Testing
- Vestibular exercises, Standard neurorehabilitation exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Istanbul Kültür University
Parkinson Disease
Efficacy of Pattern Respiratory PNF Associated Aerobic Training on Lung Volumes and 6MWT Test in Parkinson Individuals
INTRODUCTION: Parkinson's disease (PD) is a neurodegenerative disorder that causes motor disorders such as bradykinesia, rigidity and tremor.
- Trial name
- NCT02600052
- Testing
- PNF, treadmill
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Stroke
Development and Evaluation of iWalk: A Guide to Facilitate Evidence-informed Assessment of Walking After Stroke
Stroke remains a major health concern and the second highest cause of disability worldwide. After experiencing a stroke, many people lose the ability to walk independently.
- Trial name
- NCT04184843
- Testing
- iWalk Toolkit
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Cerebral Palsy
Neuromotor Control During Walking in Children With Cerebral Palsy
One out of every three children with cerebral palsy (CP) falls daily, with more than half of the falls occurring while walking. To avoid falling, the nervous system must continuously monitor how the body moves and, when an…
- Trial name
- NCT05233748
- Testing
- Stochastic Resonance (SR)
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Healthy, Gait Disorders, Neurologic
Exoskeleton and Brain Activity With fNIRS
Background. Force control is one of the major parameter of motor activity. There is few study concerning the cortical activity imply for different levels of force during gait. Objective.
- Trial name
- ExoNIRS (NCT05298943)
- Testing
- walking in 4 situations
- Where
- France
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Régional d'Orléans
Incomplete Spinal Cord Injury, Transverse Myelitis
Ultrasound Imaging Based Sensing of Human Ankle Motion Intent and Control Strategies for Ankle Assistance
Robotic therapies aim to improve limb function in individuals with neurological injury. Modulation of robotic assistance in many of these therapies is achieved by measuring the extant volitional strength of limb muscles.
- Trial name
- NCT05249595
- Testing
- Surface electromypgraphy-based interface to predict human ankle joint motion intent and use in ankle assistive devices, Ultrasound imaging-based interface to predict human ankle joint motion intent and use in ankle assistive devices, Surface electromypgraphy and ultrasound imaging-based interface to predict human ankle joint motion intent and use in ankle assistive devices
- Where
- 2 sites in United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- North Carolina State University
Spatial Neglect, Stroke
Spatial-Motor Stroke-Rehab Study
The purpose of this study is to understand how prism adaptation training with and without electrical stimulation changes visuospatial behavior, motor system neurophysiology, and walking dysfunction.
- Trial name
- NCT06053320
- Testing
- Prism adaptation therapy (PAT) + Electrical stimulation (E-stim), Gait Training
- Where
- 3 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Emory University