Clinical trials: Neurologic Complication
Diabetic Neuropathy, Painful
Study To Evaluate Efficacy, Safety And Tolerability Of Lyrica In Patients With Painful Diabetic Peripheral Neuropathy
Pregabalin has proven effective in previous clinical trails in other countries in relieving neuropathic pain associated with postherpetic neuralgia and painful diabetic neuropathy.
- Trial name
- NCT01332149
- Testing
- Pregabalin
- Where
- 30 sites in China
- Volunteers
- 626 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Arthroplasty Complications, Knee Osteoarthritis
Large Doses of Methylprednisolone Combined With Gabapentin in Total Knee Arthroplasty
The aim of the study was to assess whether administration of gabapentin and methylprednisolone as "pre-emptive analgesia" in a group of patients above 65 years of age would be effective in complex pain management therapy…
- Conditions
- Arthroplasty Complications, Knee Osteoarthritis, Pain, Postoperative, Perioperative Complication
- Trial name
- NCT04653415
- Testing
- Gabapentin 300mg, Methylprednisolone 125 mg, Tablet
- Where
- Poland
- Volunteers
- 160 people
- Sponsor
- Jagiellonian University
Post Operative Pain, Chronic Pain
Performance and Safety of the ANTALGEEK® Thess Monitoring Medical Device in the Outpatient Management of Acute Pain and Postoperative Recovery
Acute postoperative pain (APOP) is a major public health problem, affecting nearly 10 million patients in France each year. Effective analgesic therapy in the first postoperative week is a key factor in reducing early…
- Trial name
- TRACE (NCT07680998)
- Testing
- Post-operative follow-up using the Thess Telemonitoring device in conjunction with the ANTALGEEK® protocol
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Systemic Lupus Erythematosus (With and Without Nephritis), Idiopathic Inflammatory Myopathy
A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease
This is a first-in-human, single-arm, open-label study evaluating the safety, tolerability, and preliminary efficacy of ALLO-329 in adults with autoimmune diseases: systemic lupus erythematosus (SLE) with and without renal…
- Conditions
- Systemic Lupus Erythematosus (With and Without Nephritis), Idiopathic Inflammatory Myopathy, Systemic Sclerosis
- Trial name
- RESOLUTION (NCT07085104)
- Testing
- ALLO-329, Cyclophosphamide, Fludarabine
- Where
- 17 sites in United States, Canada
- Volunteers
- 66 people
- Sponsor
- Allogene Therapeutics
Postoperative Pain
The Evaluation of Mozart Music on Pain and Respiratory Rate After Thyroidectomy
To investigate the effect of Mozart music on postoperative pain and physiological parameters in patients after total thyroidectomy.
- Trial name
- NCT04699084
- Testing
- Mozart music
- Where
- Greece
- Volunteers
- 50 people
- Sponsor
- Prolepsis Institute for Preventive, Environmental and Occupational Medicine
Opioid Use, Pain, Postoperative
Collaborative Opioid Taper After Trauma: Preventing Opioid Misuse and Opioid Use Disorder
The investigators will enroll 100 participants using a randomized control trial design to implement and evaluate an individualized opioid taper program supporting rural Primary Care Physicians (PCPs) caring for patients with…
- Conditions
- Opioid Use, Pain, Postoperative, Opioid Use, Unspecified, Trauma
- Trial name
- NCT04275258
- Testing
- Provide assistance to subject's rural PCP pertaining to subject/patient pain management goals and opioid taper plan
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Washington
Pain, Postoperative
Intraoperative Pain After Infiltration Technique Using Artpharma Versus Artinibsa in Children
The aim of this study is to assess Intraoperative pain for extraction of Maxillary primary molars using Artpharma Versus Artinibsa in children during infiltration technique.
- Trial name
- NCT04221685
- Testing
- Artpharma, Artinibsa
- Volunteers
- 130 people
- Sponsor
- Cairo University
Dementia, Cognition
Cognitive and Functional Status and Dialysis Outcomes in Older Hemodialysis Patients
The purpose of this study is to estimate how quickly cognitive status and functional status in older patients on hemodialysis declines.
- Conditions
- Dementia, Cognition, End-stage Renal Disease
- Trial name
- NCT00739843
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- University of Chicago
Pain, Postoperative
Heart Rate Variability and Postoperative Pain
Postoperative pain stimulates the autonomic nervous system, induces the production of pro-inflammatory substances, reduces patient mobility and impairs vital functions.
- Trial name
- ECG-Spectral (NCT00438035)
- Testing
- ECG spectral
- Where
- France
- Volunteers
- 106 people
- Sponsor
- University Hospital, Bordeaux
Knee Injuries and Disorders, Hip Injuries and Disorders
Impact of Different Educational Approaches on Post-operative Opiate Utilization After Elective Lower Extremity Surgery
The purpose of this study is to evaluate the use of post-operative opioid use after two different educational interventions. The investigators will compare changes in pain, disability and sleep between groups 6 months after…
- Conditions
- Knee Injuries and Disorders, Hip Injuries and Disorders, Opiate Addiction
- Trial name
- OpiateLEO (NCT02997644)
- Testing
- Video Education, Usual Care Group
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Brooke Army Medical Center
Diabete Type 2
Normast3 for Adults With Diabetic Polyneuropathy
The goal of this clinical trial is to find out if a new supplement called Normast® 3 can help reduce nerve pain and improve nerve function in adults with diabetic polyneuropathy (DPN).
- Trial name
- NCT07689214
- Testing
- Normast® 3 - a food for special medical purposes (FSMP) containing co-micronized palmitoylethanolamide (PEA) with rutin and hydroxytyrosol. It is designed to support the management of diabetic polyneu
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Roma La Sapienza
Cesarean Section, Cesarean Delivery
Pain Management After Cesarean Section - A Before-and-After Cohort Study
Inadequate pain relief remains a challenge after Cesarean section (CS) and may significantly impair postoperative recovery. A recent Danish single-center study (n=100) revealed that 66% of elective CS patients experienced severe…
- Conditions
- Cesarean Section, Cesarean Delivery, Pain Management, Pain Management in Postoperative Care
- Trial name
- NCT06813638
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Nordsjaellands Hospital
Premature, Pain, Procedural
Reduction of Visual and Auditory Stimuli to Reduce Pain During Venipuncture in Premature Infants.
The aim of the study is: To evaluate the efficacy of the reduction of visual and auditory stimuli on pain during venipuncture in premature newborns of 32-36 weeks of gestation.
- Trial name
- VENOPUNCIPREM (NCT04041635)
- Testing
- Stimuli reduction, Usual care
- Where
- Spain
- Volunteers
- 52 people
- Sponsor
- Germans Trias i Pujol Hospital
Pain, Postoperative, Healing Surgical Wounds
Comparative Evaluation of Various Patient Centered Outcomes Following Gingival Depigmentation Using Diode LASER in Different Modes: A Randomized Clinical Trial
Purpose of this study is to clinically evaluate and compare various patient centered outcomes using diode LASER in Continuous mode (CW) and Pulsed Mode (PM) using 300µm and 400µm fiber for depigmentation procedure.
- Conditions
- Pain, Postoperative, Healing Surgical Wounds, Analgesia, Temperature Change, Body
- Trial name
- LASER (NCT04217434)
- Testing
- 400 µm fibre length will be used in continuous contact mode, 400 µm fibre length will be used in pulsed contact mode, 300 µm fibre length will be used in continuous mode
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Orthostatic Intolerance, Orthostatic Hypotension
Postoperative Orthostatic Intolerance and Hypotension in Unilateral TKA
Incidence of Postoperative Orthostatic Intolerance and Postoperative Orthostatic Hypotension in Patients Undergoing Unilateral Total Knee Arthroplasty
- Conditions
- Orthostatic Intolerance, Orthostatic Hypotension, Postoperative Complications
- Trial name
- NCT03743116
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Hvidovre University Hospital
Post-operative Pain
TAP Block: Does Volume Make a Difference?
Patients who have abdominal surgery will experience pain from the incision. The lumbar TAP block is a procedure used to reach the nerve endings in the abdominal wall so that there is a reduction in pain after surgery.
- Trial name
- NCT01307215
- Testing
- Ropivacaine
- Where
- Canada
- Volunteers
- 31 people
- Sponsor
- McMaster University
Pain, Postoperative
Erector Spinae Block Versus Thoracic Paravertebral Block for Postoperative Pain Control After Open Nephrectomy
the study aims to compare the analgesic efficacy of erector spinae plane block versus thoracic paravertebral block after open nephrectomy surgery.
- Trial name
- NCT04719507
- Testing
- erector spinae block, thoracic paravertebral block, Pethidine Only Product in Parenteral Dose Form
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pain Management After Surgery
Evaluation of the Effect of Virtual Reality Application on Postoperative Pain and Anxiety in Women Aged 50-70
Surgical interventions, while significant milestones in patients\' physical recovery processes, can be a major source of concern for patients due to postoperative pain, which is also an important component of postoperative…
- Trial name
- Pain (NCT06436014)
- Testing
- Providing VR experience
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Osmaniye Korkut Ata University
Post Operative Pain
A Comparative Study Between Ultrasound Guided Erector Spinae Plane Block and Combined Ultrasound Guided Pericapsular Nerve Group and Lateral Femoral Nerve Block Following Total Hip Arthroplasty
The patients will be randomized into 2 equal groups by a computer-generated random numbers table, named group A, B. Group A: patients will receive Pericapsular nerve group block and lateral femoral cutaneous nerve blocks.
- Trial name
- NCT06402006
- Testing
- PENG block, LFCN block, ESP block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Symptomatic Irreversible Pulpitis, Symptomatic Irreversible Pulpitis (SIP)
Postoperative Pain After Pulpotomy in Children Using Calcium Silicate Cements With and Without Laser Therapy
This study evaluates treatment options for children and young adults with severe toothache in a permanent molar caused by symptomatic irreversible pulpitis.
- Trial name
- NCT07290049
- Testing
- Calcium Silicate Cement, Er,Cr:YSGG Laser
- Where
- United Arab Emirates
- Volunteers
- 46 people
- Sponsor
- University of Fujairah
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