Clinical trials: Neurologic Complications
Postoperative Pain
Efficacy of Fentanyl Soaked Nasal Packs on Postoperative Pain in Nasal Surgeries.
Efficacy of fentanyl soaked nasal packs on postoperative pain in nasal surgeries.
- Trial name
- NCT06531759
- Testing
- Fentanyl
- Volunteers
- 100 people
- Sponsor
- Assiut University
Postoperative Pain
Postoperative Analgesic Effectiveness of Fascial Plane Blocks in Breast Surgery
This prospective, single-center observational study will compare postoperative pain control in adults undergoing elective breast surgery.
- Trial name
- NCT07830446
- Testing
- Rhomboid intercostal plane block, Serratus posterior superior intercostal plane block, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Neurologic Complication, Neurosurgery
The Potential Impact of Clindamycin on Neurosurgery Patients.
A prospective, open-label, single center, controlled trial. 44 patients that underwent neurosurgery or presented meningitis signs, for whom Clindamycin add-on therapy to assess its effect on neurological complication in relation…
- Trial name
- NCT06068673
- Testing
- Clindamycin 600 mg, standard regimen
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Damanhour University
Analgesia
Analgesia After Total Knee Arthroplasty
The recovery from knee replacement surgery often involves a significant amount of pain. The best way to prevent/treat this pain is unknown.
- Trial name
- NCT00869037
- Testing
- Periarticular Injection, CFNB + Posterior Capsular Injection
- Where
- Canada
- Volunteers
- 90 people
- Sponsor
- University of Manitoba
Post-surgical Pain, Pain, Acute
Online Psychology Program for Chronic Pain After Surgery
This project will evaluate the feasibility of a new fully self-guided online Acceptance and Commitment Therapy (ACT) program entitled Advancing Online Psychology Tools for the Transitional Pain Service (ADOPT-TPS), developed on…
- Conditions
- Post-surgical Pain, Pain, Acute, Pain, Chronic, Post-Surgical Pain, Chronic
- Trial name
- ADOPT-TPS (NCT06455345)
- Testing
- Self-Guided Online ACT Program, Treatment As Usual
- Where
- 2 sites in Canada
- Volunteers
- 68 people
- Sponsor
- University Health Network, Toronto
Ovarian Cancer, Malnutrition
Exercise and Nutrition Intervention in Ovarian Cancer
The objective of this multicenter randomized controlled trial is to compare a 6-month exercise and nutrition intervention (intervention group, IG) aimed at maintaining or improving physical functioning and quality of life with…
- Conditions
- Ovarian Cancer, Malnutrition, Muscle Wasting, Fatigue
- Trial name
- BENITA (NCT06250686)
- Testing
- combined exercise and nutrition intervention
- Where
- 7 sites in Germany
- Volunteers
- 185 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Postoperative Pain
Parental Self-Efficacy for Child Autonomy and Postoperative Pain in Children Undergoing Minor Surgery
This study aims to examine the relationship between parental self-efficacy in supporting child autonomy and postoperative pain levels in children undergoing minor surgical procedures.
- Trial name
- PSE-PAIN-MS (NCT07381673)
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Agri Ibrahim Cecen University
Acut Postoperative Pain, Erector Spinae Plane Block
Comparison of Intertransverse Process and Erector Spinae Plane Blocks in Acute Postoperative Analgesia Management for Laparoscopic Cholecystectomy Patients
Laparoscopic cholecystectomy is considered the gold standard for the surgical treatment of benign gallbladder diseases; however, despite its minimally invasive nature, a significant proportion of patients experience substantial…
- Conditions
- Acut Postoperative Pain, Erector Spinae Plane Block, Intertransverse Process Block
- Trial name
- NCT07504705
- Testing
- Intertransverse Process Block, Erector Spinae Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Konya City Hospital
Appendectomy, Laparoscopic, Pediatric Anesthesia
Rectus Sheath Block and Local Wound Infiltration in Pediatric Laparoscopic Appendectomies
Laparoscopic appendectomy surgeries are among the most commonly performed procedures in childhood. However, they are associated with moderate to severe postoperative pain.
- Conditions
- Appendectomy, Laparoscopic, Pediatric Anesthesia, Nerve Block/Methods, Regional Anesthesia
- Trial name
- NCT06913205
- Where
- Turkey (Türkiye)
- Volunteers
- 145 people
- Sponsor
- Bursa City Hospital
Endometriosis, Dyspareunia
Transvaginal Low-level Laser Therapy to Improve Pelvic Pain and Sexual Function in Patients with Endometriosis.
Dyspareunia is defined as pain with penetrative sexual intercourse. Women with endometriosis have a nine-fold increased risk of dyspareunia, when compared to the general female population.
- Conditions
- Endometriosis, Dyspareunia, Pelvic Pain
- Trial name
- NCT05540353
- Testing
- Transvaginal photobiomodulation
- Where
- 6 sites in United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Medstar Health Research Institute
Postoperative Pain
US Guided EOI Block Versus ESPB for Postoperative Analgesia in Laparoscopic Cholecystectomy
To compare the efficacy of USG-guided bilateral External oblique intercostal (EOI) block with Erector spinae plane block (ESPB) for post-operative analgesia after laparoscopic cholecystectomy with a hypothesis that both External…
- Trial name
- NCT05272280
- Testing
- External oblique intercostal (EOI) block, Erector spinae plane block (ESPB)
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Low-level Laser Acupuncture in Patients With Total Knee Arthroplasty
Low-level Laser Acupuncture Reduces Postoperative Pain and Morphine-related Side Effects in Patients With Total Knee Arthroplasty:
Total knee arthroplasty is a common and effective surgical procedure for patients with end-stage knee osteoarthritis, and wound pain is still a problem for many of the patients.
- Trial name
- NCT03995446
- Testing
- low-level laser
- Where
- Taiwan
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Post Operative Pain
Ultrasound-guided Transversus Abdominis Plane Block After Hysterectomy
In this randomized, controlled, observer-blinded study we plan to evaluate ultrasound-guided transversus abdominis plane (TAP) block for postoperative pain management in patients undergoing abdominal hysterectomy.
- Trial name
- TAP (NCT01153503)
- Testing
- TAP block
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Postoperative Pain
The Effect of Coenzyme Q10 in Preventing Pain After Thoracoscopic Surgery
This study aimed to assess the effectiveness of Coenzyme Q10 in preventing both acute and chronic pain following thoracoscopic surgery, with a focus on its potential benefits in reducing the incidence and severity of pain.
- Trial name
- NCT06743802
- Testing
- Coenzyme Q10
- Where
- China
- Volunteers
- 264 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Surgical Stress Response, Stress Physiological
Feasibility of Breathwork Intervention With Older Adults After Knee Surgery
Postoperative complications after surgical procedures, including following total knee arthroplasty (TKA), have a negative impact on the health and well-being of surgical patients.
- Conditions
- Surgical Stress Response, Stress Physiological, Stress Physiology, Stress Psychological
- Trial name
- NCT07464860
- Testing
- A 5-minute Asynchronous Breathwork Intervention, A 5-minute Asynchronous Card Game Video
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Postoperative Delirium (POD), Postoperative Sleep Disturbance
Effects of Esketamine on the Incidence of Postoperative Delirium and Postoperative Sleep Disturbance in Elderly Patients After Major Non-cardiac Surgery
Postoperative delirium (POD) is a common surgical complication.It is associated with a range of negative outcomes such as delayed postoperative recovery,prolonged hospitalization,additional medical expenditures and higher…
- Trial name
- EPISODE (NCT06900205)
- Testing
- Esketamine, 0.9 % saline
- Where
- China
- Sponsor
- RenJi Hospital
Postoperative Pain
Femoral or Sciatic Nerve Block to Provide Analgesia After Proximal Tibial Osteotomy
Proximal tibial osteotomy is associated with moderate to severe postoperative pain. The proximal part of the tibia is innervated by branches from the femoral nerve anteriorly and the sciatic nerve posteriorly.
- Trial name
- NCT05728294
- Testing
- Femoral nerve block with ropivacaine 0.5%, 20 ml, Sciatic nerve block with ropivacaine 0.5%, 20 ml
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Spinal Cord Injuries (SCI), Urinary Retention
Clinical Trial of Abdominal Breathing for Urinary Retention After Spinal Cord Injury
Randomized controlled trials were conducted in patients with urinary retention after spinal cord injury. The effects of abdominal breathing training on pelvic floor muscle tone, muscle strength and residual urine volume in…
- Trial name
- NCT06964256
- Testing
- Abdominal breathing exercises, Control group: intermittent catheterization, Experimental group: intermittent catheterization
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Qilu Hospital of Shandong University
Bacterial Infections, Bone Diseases, Infectious
Fosfomycin I.v. for Treatment of Severely Infected Patients
The purpose of this European, multicentric, prospective, non-interventional study is to document and evaluate the efficacy and safety of the treatment of severely infected patients with intravenously administered fosfomycin…
- Conditions
- Bacterial Infections, Bone Diseases, Infectious, Osteomyelitis, Central Nervous System Bacterial Infections
- Trial name
- FORTRESS (NCT02979951)
- Where
- 50 sites in Austria, Germany and 3 more
- Volunteers
- 1,000 people
- Sponsor
- Infectopharm Arzneimittel GmbH
Postoperative Pain, Postoperative Complications
Local Anesthetic Automated Intermittent Administration vs. Continuous Infusion Via Femoral Nerve Block.
This study evaluates the impact of local anesthetic administration regiment through peri-neural femoral nerve catheter on pain and motor block frequency, after total knee arthroplasty.
- Trial name
- NCT03696095
- Testing
- Ropivacaine Hcl 0.2% Inj Bag 200Ml (PIB mode), Ropivacaine Hcl 0.2% Inj Bag 200Ml (CI mode)
- Where
- Belgium
- Volunteers
- 70 people
- Sponsor
- J P Lecoq
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