Clinical trials: Neurologic Complications
Nerve Block, Pain, Postoperative
TAP vs. ESP Block for Gynecological Post Operative Pain
The goal of this double blind randomized controlled trial is to compare transversus abdominis plane block and erector spinae plane block in gynecological surgery patients.
- Trial name
- NCT06044779
- Testing
- Transversus Abdominis Plane Block using 0.25% Bupivacaine, Erector Spinae Plane Block using 0.25% Bupivacaine
- Where
- Indonesia
- Volunteers
- 40 people
- Sponsor
- Universitas Padjadjaran
Eye Trauma
Playtime Open Globe Injuries in Children
This study investigated the epidemiology, aetiologies, and complications of playtime open-globe injuries in children at the Assiut University Hospital, Egypt, between January to July 2016.
- Trial name
- NCT04497896
- Testing
- Repair of open globe injury
- Volunteers
- 81 people
- Sponsor
- Assiut University
Postoperative Pain
Analgesic Efficacy of Fascia Iliaca Compartment Block Compared With Intrathecal Nalbuphine for Hip Surgery Under Spinal Anesthesia
It is already known that fascia iliaca compartment block and intrathecal nalbuphine are very effective ways in postoperative pain control in patients having hip surgeries.
- Trial name
- NCT06818396
- Testing
- US-guided fascia iliaca compartment block (FICB) and spinal anesthesia, Intrathecal nalbuphine and spinal anesthesia, Spinal anesthesia
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Postoperative Pain
Peritoneal Nebulization of Ropivacaine for Pain Control After Laparoscopic Colectomy
The purpose of this study is to assess if intraperitoneal nebulization of Ropivacaine 150 mg produces better postoperative pain control than Saline nebulization after laparoscopic colectomy.
- Trial name
- NCT01432496
- Testing
- Ropivacaine 150 mg, saline 15 ml
- Where
- 3 sites in Italy
- Volunteers
- 130 people
- Sponsor
- San Gerardo Hospital
Anaplastic Astrocytoma, Anaplastic Oligoastrocytoma
Vaccine Therapy With or Without Sirolimus in Treating Patients With NY-ESO-1 Expressing Solid Tumors
This phase I trial studies the side effects and best schedule of vaccine therapy with or without sirolimus in treating patients with cancer-testis antigen (NY-ESO-1) expressing solid tumors.
- Conditions
- Anaplastic Astrocytoma, Anaplastic Oligoastrocytoma, Anaplastic Oligodendroglioma, Estrogen Receptor Negative
- Trial name
- NCT01522820
- Testing
- DEC-205/NY-ESO-1 Fusion Protein CDX-1401, Laboratory Biomarker Analysis, Pharmacological Study
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Roswell Park Cancer Institute
Anesthesia, Postoperative Delirium
STimulation Electronically of Acupoints for Postoperative Delirium in elderlY Patients
Transcutaneous electrical acupoint stimulation (TEAS) was reported to benefit the patients undergoing surgeries by reducing anesthetics consumption and decreasing anesthesia related adverse effects.
- Conditions
- Anesthesia, Postoperative Delirium, Electroencephalogram
- Trial name
- STEADY (NCT06161662)
- Testing
- transcutaneous electrical acupoint stimulation, Control
- Where
- China
- Volunteers
- 226 people
- Sponsor
- Zhihong LU
Postoperative Pain, Lumbar Surgery
Retrolaminar Analgesia for LuMbar Surgery
This randomized controlled trial evaluates the effectiveness of ultrasound-guided retrolaminar nerve block in addition to standard multimodal analgesia for postoperative pain management in patients undergoing lumbar spine…
- Conditions
- Postoperative Pain, Lumbar Surgery, Back Pain Lower Back Chronic, Opioid Analgesia
- Trial name
- REALM (NCT07334288)
- Testing
- Ultrasound-Guided Retrolaminar Block, Standard Analgesia
- Where
- Chile
- Volunteers
- 50 people
- Sponsor
- Universidad de los Andes, Chile
Postoperative Acute Pain, Breast Cancer
IPP-PSP Block vs. SPSIPB in Breast Surgery
This prospective, randomized clinical study aims to compare the analgesic efficacy of the interpectoral-pectoserratus plane block and the serratus posterior superior intercostal plane block for postoperative pain management in…
- Conditions
- Postoperative Acute Pain, Breast Cancer, Regional Anesthesia
- Trial name
- NCT07246720
- Testing
- Interpectoral-Pectoserratus Plane Block, Serratus Posterior Superior Intercostal Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Zonguldak Bulent Ecevit University
Diabetic Peripheral Neuropathy Type 2
Concurrent Training vs Soleus Push-Ups on Neurogenesis-Related Biomarkers in Diabetic Neuropathy Patients
This study will examine how two types of exercise programs affect nerve health in people with diabetic peripheral neuropathy. Diabetic peripheral neuropathy is a common complication of type 2 diabetes that can cause numbness…
- Trial name
- NCT07675720
- Testing
- Concurrent Training, Soleus Push-ups
- Where
- Pakistan
- Volunteers
- 99 people
- Sponsor
- Riphah International University
Postoperative Pain
Evaluation of Preoperative Use of Pregabalin on Postoperative Analgesia After Laparoscopic Colorectal Surgery
The purpose of this study is to evaluate how effective is the preoperative administration of pregabalin 300mg, to attenuate postoperative pain and opioids consumption after laparoscopic colorectal surgery
- Trial name
- NCT01940224
- Testing
- Pregabalin, Morphine
- Where
- Greece
- Volunteers
- 50 people
- Sponsor
- Larissa University Hospital
Femoral Fractures, Postoperative Pain
Comparison of Two Different Approaches in the Fascia Iliaca Compartment Block in Femoral Fracture Surgery
Fascia Iliaca Compartment Block (FICB) is a popular regional anaesthetic technique for surgical procedures involving the hip joint and femur.
- Trial name
- NCT05172869
- Testing
- Suprainguinal Performed FICB, Infrainguinal Performed FICB
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Ankara City Hospital Bilkent
Ehlers-Danlos Syndrome (EDS)
Impact of Ehlers-Danlos Syndrome on Gynaecological Health
Dysmenorrhea is a common problem in gynaecology, significantly impacting patients' quality of life. Ehlers-Danlos syndrome (EDS) is associated with joint hypermobility, tissue fragility and chronic pain.
- Trial name
- GYNESED (NCT07151274)
- Where
- France
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
Postoperative Pain, Postoperative Return of Bowel Function
Effect of Intraoperative Intravenous Lidocaine on Postoperative Pain and Return of Bowel Function After Cesarean Sections
Postoperative discomfort is a frequently seen adverse event after to caesarean operation. Early mobilization and bonding of the mother and her infant are typically impacted by this phenomenon.
- Trial name
- NCT06433713
- Testing
- Lidocaine IV
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Arthroplasty, Replacement, Knee, Pain, Postoperative
Adductor Canal Block for Total Knee Arthroplasty
Total knee arthroplasty (TKA) can be associated with a large amount of postoperative pain. This pain can oftentimes be severe enough to limit participation in physical therapy and ultimately delay discharge resulting in increased…
- Trial name
- NCT02453360
- Testing
- Adductor Canal Block
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Wisconsin, Madison
Diabetic Foot Ulcer
Effect of Virtual Reality on Pain, Anxiety and Vital Signs During Diabetic Foot Care
This study aims to determine the effects of a virtual reality (VR) intervention on pain level, state anxiety, and vital signs during foot care in individuals with diabetic foot ulcers.
- Trial name
- NCT07586423
- Testing
- VR, Standard Diabetic Foot Care
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Malatya Turgut Ozal University
Urolithiasis, Nephrolithotomy
Exit Strategy After Percutaneous Nephrolithotomy: Large or Small Bore Tube?
Regarding to the distribution of nephrostomy tube (NT) size usage by country. There was a clear distinction between countries that used solely the small bore (SB) NT (Chile and Australia) and those that used solely the large bore…
- Conditions
- Urolithiasis, Nephrolithotomy, Percutaneous Nephrolithotomy (PNL), Nephrostomy Tube (NT)
- Trial name
- NCT04153474
- Testing
- large-bore nephrostomy tube (LBNT), small-bore nephrostomy tube (SBNT)
- Where
- Egypt
- Volunteers
- 220 people
- Sponsor
- Mansoura University
Postoperative Delirium (POD), Frailty at Older Adults
Associations of Postoperative Delirium With Perioperative Frailty Worsening and Their Combined Effect on 1-Year Mortality in Older Surgical Patients
Postoperative delirium (POD) is a frequent complication in older surgical patients and is associated with adverse outcomes, while frailty is also highly prevalent during the perioperative period.
- Conditions
- Postoperative Delirium (POD), Frailty at Older Adults, Mortality, Recovery of Function
- Trial name
- NCT07259850
- Where
- China
- Volunteers
- 6,196 people
- Sponsor
- Chinese PLA General Hospital
Ultrasound Guided Rectus Sheath Block, Pain, Postoperative
Comparison Between Ultra Sound Guided Rectus Sheath Block and Field Block for Midline Hernia Repair
Randomized double blinded controlled clinical trial will be done with a total number of 75 patients will be divided into 3 groups.
- Trial name
- NCT03225313
- Testing
- Bupivacaine Hydrochloride 0.5% Injection Solution_#4, Normal Saline Flush, 0.9% Injectable Solution_#5
- Where
- Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Theodor Bilharz Research Institute
Postoperative Pain, Laparoscopic Hysterectomy
Impact of Preoperative Quadratus Lumborum Block on Postoperative Opioid Consumption After Laparoscopic Hysterectomy
The goal of this clinical trial is to learn if preoperative nerve block (quadratus lumborum [QL] block) works to improve pain control during and after laparoscopic hysterectomy.
- Conditions
- Postoperative Pain, Laparoscopic Hysterectomy, Nerve Block, Quadratus Lumborum Block
- Trial name
- NCT06709716
- Testing
- Quadratus Lumborum Block (QLB), Quadratus lumborum block, Local Anesthetic Solution
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Walter Reed National Military Medical Center
Neurogenic Bladder
Educational Video for Neurogenic Bladder
This study is designed to assess the efficacy of educational materials in parents of children with neurogenic bladder considering surgical reconstruction.
- Trial name
- NCT05482347
- Testing
- Educational video
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- University of Colorado, Denver
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