Clinical trials: Neurologic Complications
Vulvodynia (Chronic Vulvar Pain), Vulvar Vestibulitis
Does a Virtual Program for Pelvic Pain Improve Pain and Sexual Outcomes in Individuals With Provoked Vestibulodynia?
The goal of this clinical trial is to learn if a 3-month online pelvic health program works to improve pain and sexual wellbeing in adult women with chronic genital pain.
- Conditions
- Vulvodynia (Chronic Vulvar Pain), Vulvar Vestibulitis, Vestibulodynia, Provoked Vestibulodynia
- Trial name
- PVD (NCT06999395)
- Testing
- Virtual online pelvic health program
- Where
- Canada
- Volunteers
- 250 people
- Sponsor
- Queen's University
Breast Neoplasms, Pain, Postoperative
Serratus Anterior Plane Block to Prevent Chronic Postoperative Pain in Breast Cancer
Chronic postoperative pain (CPP) remains a disturbing and obscure clinical problem. The hypothesis of this trial is that a peripheral block of the serratus anterior plane block type preoperatively after a modified radical…
- Conditions
- Breast Neoplasms, Pain, Postoperative, Pain, Chronic, Post-Mastectomy Chronic Pain Syndrome
- Trial name
- USB22 (NCT05494281)
- Testing
- Serratus Anterior Plane Block with local anesthetic, Serratus Anterior Plane Block with saline solution
- Where
- Morocco
- Volunteers
- 94 people
- Sponsor
- Moroccan Society of Surgery
Post-operative Pain, Acute
To Compare the Skin Incision Made by the Electrocautery and Scalpel in Inguinal Hernia Repair
The Groin hernia repair is a commonly performed general surgery procedure in both adults and children with inguinal hernias constituting more than 95% of all groin hernia repairs.
- Trial name
- NCT05666973
- Testing
- Open Mesh Hernioplasty
- Volunteers
- 60 people
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.
Postoperative Pain, Pelvic Organ Prolapse
The Effect of Local Analgesia on Postoperative Gluteal Pain in Patients Undergoing Sacrospinous Ligament Fixation
This study will randomize patients to either receive intraoperative administration of local anesthetic and corticosteriod at time of sacrospinous ligament fixation compared to placebo to determine if intraoperative trigger point…
- Conditions
- Postoperative Pain, Pelvic Organ Prolapse, Trigger Point Injection, Sacrospinous Ligament Fixation
- Trial name
- NCT03995641
- Testing
- marcaine and kenalog
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Kettering Health Network
Erector Spinae Plane Block, Serratus Posterior Superior Intercostal Plane Block
Comparison of Erector Spinae Plane Block and Serratus Posterior Superior Intercostal Plane Block
Breast cancer is the most common malignancy in women. Modified radical mastectomy, a surgical procedure in the treatment of breast cancer, is one of the standard treatments.
- Conditions
- Erector Spinae Plane Block, Serratus Posterior Superior Intercostal Plane Block, Acute Pain, Postoperative Pain
- Trial name
- NCT06407037
- Testing
- Erector Spinae Plane Block, Serratus Posterior Superior Intercostal Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Postoperative Pain
RADA16 for Adult Tonsillectomy
The purpose of the research is to determine if RADA16 (also known as PuraStat®, PuraGel®, or PuraSinus®) improves patient outcomes following tonsillectomy procedures.
- Trial name
- NCT07060495
- Testing
- RADA16 hydrogel
- Where
- 2 sites in United States
- Volunteers
- 134 people
- Sponsor
- Rutgers, The State University of New Jersey
Postoperative Pain, Chest Pain
Transversus Thoracis Muscle Plane Block for Postoperative Pain in Adult Cardiac Surgery
Inadequate pain control after coronary artery bypass graft surgery increases mortality and results in a higher incidence of persistent poststernotomy pain syndrome.
- Conditions
- Postoperative Pain, Chest Pain, Coronary Artery Bypass, Sternotomy
- Trial name
- NCT04591119
- Testing
- Transversus Thoracic Muscle Plane Block, Parasternal Intercostal Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Muğla Sıtkı Koçman University
Perioperative/Postoperative Complications, Postoperative Cognitive Dysfunction
CEReBral AutorEgulation in Non-cardiac SuRgery and Relationship to Postoperative DeliriUm State
The goal of this observational study is to learn the how to determine the mean arterial pressure(MAP) or blood pressure level to be maintained during non-cardiac surgery for optimal brain health in patients above the age of 60…
- Conditions
- Perioperative/Postoperative Complications, Postoperative Cognitive Dysfunction, Postoperative Delirium, EEG With Periodic Abnormalities
- Trial name
- CERBERUS (NCT06133842)
- Testing
- Intra-op EEG and CO data collection
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Inflammation, Osteoarthritis
Photobiomodulation Therapy in Patients Receiving Total Knee Arthroplasty
Photobiomdoulation is the use of near-infrared light to relieve pain, stimulate healing and reduce inflammation. Swelling and inflammation is a common condition after orthopedics surgeries over extremity and spine.
- Conditions
- Inflammation, Osteoarthritis, Post Operative Pain
- Trial name
- NCT06426251
- Testing
- Photobiomodulation
- Where
- Taiwan
- Volunteers
- 15 people
- Sponsor
- National Taiwan University Hospital Hsin-Chu Branch
Pain, Postoperative
Ultrasound-Guided Thoracic Paravertebral Blocks in Patients Undergoing Reduction Mammoplasty
Background: Thoracic paravertebral blocks (TPVBs) have been effective for postoperative analgesia in mastectomy, thoracic and video-assisted thoracic surgeries.
- Trial name
- NCT02671851
- Testing
- Thoracic paravertebral blocks (TPVBs), IV metamizole sodium, paracetamol
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Istanbul University
Post-Surgical Complication, Breast Cancer Surgery
The Efficacy of Using Pentoxifylline in Patients Undergoing Breast Cancer Surgery
The goal of this clinical trial is to assess the efficacy of pentoxifylline in reducing postsurgical complications for breast cancer patients undergoing breast cancer surgery.
- Trial name
- NCT06087237
- Testing
- Pentoxifylline, paracetamol +ketorolac
- Where
- Egypt
- Volunteers
- 92 people
- Sponsor
- Mansoura University
Chronic Post Operative Pain, Kidney Transplant; Complications
Post-surgical Chronic Pain After Retroperitoneal Laparoscopic Living Kidney Donor
This study aimed to determine the relationship between the quadratus lumborum and erector spinae plane block technique and the incidence and severity of chronic post-surgical pain in accordance with Brief Pain Inventory Score…
- Conditions
- Chronic Post Operative Pain, Kidney Transplant; Complications, Anesthesia Regional, Laparoscopy
- Trial name
- NCT05572775
- Testing
- Quadratus lumborum (QL) block, Erector Spinae Plane (ESP) Block
- Where
- Indonesia
- Volunteers
- 146 people
- Sponsor
- Universitas Indonesia
Chronic Pain, Cesarean Section Complications
Intra-epidermal Nerve Fibre Density and Its Relationship to Post-caesarean Section Pain
Chronic pain is a significant burden to the individual and society with post-surgical pain identified as a research priority for the speciality of anaesthesia.
- Trial name
- NCT03715075
- Testing
- Caesarean Section
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Royal Infirmary of Edinburgh
Diabetic Neuropathy, Painful; Diabetic Neuropathies
Safety, Tolerability and Preliminary Efficacy of AZD5213 in Combination With Pregabalin in Subjects With PDN and Good Pain Reporting Ability
This is a 2-part study. In Part 1 of the study, subjects will undergo a pain reporting training program in which a painful stimulus will be applied to the subject's hand, and the subjects will be asked to report how painful the…
- Trial name
- NCT01928381
- Testing
- AZD5213 + pregabalin, pregabalin capsules
- Where
- 9 sites in United States
- Volunteers
- 150 people
- Sponsor
- AstraZeneca
Pain, Postoperative, Ketamine Adverse Reaction
Neuropsychiatric and Cardiovascular Side Effects in Ketamine Analgesic Infusions
Evaluation of neuropsychiatric and cardiovascular side effects of low dose ketamine analgesic infusion for postoperative pain
- Trial name
- NCT03525912
- Testing
- Ketamine
- Where
- Colombia
- Volunteers
- 101 people
- Sponsor
- Universidad de Antioquia
Total Shoulder Arthroplasty
Exparel for Total Shoulder Arthroplasty
The primary objective of this study is to determine if Exparel leads to better pain scores at 24, 48 and 72 hours after Total Shoulder Arthroplasty (TSA) compared to a pain pump.
- Trial name
- NCT04364867
- Testing
- Exparel, Pain Pump
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Norton Healthcare
Post-surgical Pain
Hydromorphone Hydrochloride Epidural Preemptive Analgesia for Postoperative Pain After Cesarean Section
Acute pain often occurs after cesarean section, which can lead to stress and inflammatory response in the body, which will not only affect the postpartum recovery speed of the puerpera, but also inhibit the secretion of prolactin…
- Trial name
- HHEPA (NCT06823180)
- Testing
- Hydromorphone hydrochloride low dose, Hydromorphone hydrochloride high dose, 0.9% sodium chloride
- Where
- China
- Volunteers
- 105 people
- Sponsor
- Liquan Liang
Pain, Post Operative
Nerve Block Versus Non-targeted Local Anaesthesia in Breast Surgery
Effective postoperative pain control is an essential component of surgery. Adequate analgesia improves patient comfort and satisfaction, thereby permitting earlier mobilisation, faster recovery and less likelihood of…
- Trial name
- NCT02410746
- Testing
- targeted chirocaine pec block, standard chirocaine infiltration, standard post-operative analgesia
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- BMI Healthcare
Hypothermia
Study to Determine the Effects of Pre-warming on OR Patient Temperatures and Surgical Outcomes
The application of active warming to patients whether awake or under general anesthesia has been proven safe in numerous studies and it is common practice to use warmers.
- Trial name
- NCT02177903
- Testing
- Bair Paws Patient Adjustable Warming System
- Where
- Canada
- Volunteers
- 220 people
- Sponsor
- Solventum US LLC
Post Operative Pain
The Efficacy of SPSIPB on Postoperative Pain and Analgesic Consumption in Patients Undergoing VATS
The aim of this study is to investigate the postoperative analgesic efficacy of SPSIPB and its effect on opioid consumption in patients undergoing video-assisted thoracoscopic surgery (VATS).
- Trial name
- NCT05901103
- Testing
- Serratus posterior superior intercostal plane block (SPSIPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Cumhuriyet University
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