Clinical trials: Neurologic Complications
Pain, Postoperative
A Study Comparing the Effectiveness and Safety of Extended Release (ER) Tramadol Hydrochloride (HCl)/Acetaminophen With Immediate Release (IR) Tramadol HCl/Acetaminophen in Participants With Moderate to Severe Postoperative Pain
The purpose of this study is to compare the efficacy and safety of extended release (ER) tramadol hydrochloride (HCl)/acetaminophen with immediate release (IR) tramadol HCl/acetaminophen in participants with moderate to severe…
- Trial name
- NCT01814878
- Testing
- Tramadol HCl/Acetaminophen ER, Tramadol HCl/Acetaminophen IR
- Volunteers
- 320 people
- Sponsor
- Janssen Korea, Ltd., Korea
Intracranial Tumors
The Effect of Ciprofol Versus Propofol Anesthesia on Postoperative Neurological Complications
Postoperative delirium and postoperative ischemic stroke are common neurological complications in clinical practice. The incidence of these complications is further increased in patients undergoing neurosurgical procedures.
- Trial name
- NCT07805876
- Testing
- Ciprofo, Propofol
- Where
- China
- Volunteers
- 434 people
- Sponsor
- Beijing Tiantan Hospital
Pain, Postoperative
Do Patient Educational Videos Improve Pain and Recovery After Laparoscopic Hysterectomy?
The use of multi-model patient education has been used in a variety of medical specialties to educate patients on expectations for various medical procedures and improve patients' understanding of their own health care.
- Trial name
- NCT06265376
- Testing
- Educational Video
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Benaroya Research Institute
Growth Hormone Deficiency, Idiopathic Short Stature
Long-term Safety and Effectiveness of Growtropin®-II Treatment in Children With Short Stature
This study evaluates long-term safety and effectiveness of Growtropin®-II treatment in children with short stature.
- Conditions
- Growth Hormone Deficiency, Idiopathic Short Stature, Turner Syndrome, Small for Gestational Age
- Trial name
- NCT04798690
- Where
- South Korea
- Volunteers
- 5,000 people
- Sponsor
- Dong-A ST Co., Ltd.
Impacted Lower Third Molar, Alveolar Bone Regeneration Following Odontectomy
Evaluating The Use of CGF Made Gel in Mandibular Extraction Sites of Lower Impacted 3rd Molars.
The goal of this clinical trial is to learn if Concentrated Growth Factor (CGF) Gel help improve bone healing and reduce pain after the surgical removal of impacted lower third molars.
- Conditions
- Impacted Lower Third Molar, Alveolar Bone Regeneration Following Odontectomy, Postoperative Pain Management in Oral Surgery, Concentrated Growth Factor for Extraction Socket Healing
- Trial name
- CGF (NCT07520097)
- Testing
- Concentrated Growth Factor (CGF) Gel
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University
Post Operative Pain
Comparison of Post Operative Pain in Resin-Based and Bioceramic Based Root Canal Sealers in Patient Presenting at Peshawar Dental College.
The goal of this clinical trial is to compare the post operative pain in Resin-Based and Bio ceramic based sealers in patients presenting at Peshawar dental college.
- Trial name
- NCT07253025
- Testing
- Resin based root canal sealer, Bioceramic based root canal sealer
- Where
- Pakistan
- Volunteers
- 180 people
- Sponsor
- Prime Foundation
Preoperative, Sleep Disturbance
Preoperative Oral Midazolam to Postoperative Pain Relief in Sleep Disturbance or Anxiety Patients With Colorectal Cancer
Previous studies have indicated a high incidence of sleep disturbances and anxiety symptoms in individuals with colorectal cancers prior to undergoing surgery, leading to worsened postoperative pain, slower recovery, and higher…
- Conditions
- Preoperative, Sleep Disturbance, Anxiety, Midazolam
- Trial name
- POMPPR (NCT06407518)
- Testing
- Midazolam oral solution
- Where
- China
- Volunteers
- 280 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Pelvic Pain, Endometriosis
The Women's Health Study: From Adolescence to Adulthood
In order to learn more about women's health issues that occur over the lifespan, the Women's Health Study: from Adolescence to Adulthood is building a biorepository and database.
- Conditions
- Pelvic Pain, Endometriosis, Dysmenorrhea, Infertility
- Trial name
- WHS:A2A (NCT01738204)
- Where
- 2 sites in United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Postoperative Pain, Shoulder Arthroscopy
Interscalene Brachial Plexus Block Versus Serratus Posterior Superior Intercostal Plane Block for Arthroscopic Shoulder Surgery
Arthroscopic shoulder surgery is associated with moderate to severe postoperative pain that may delay recovery and rehabilitation.
- Trial name
- SISA (NCT07668648)
- Testing
- Interscalene Brachial Plexus Block, Serratus Posterior Superior Intercostal Plane Block, Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ferit Yetik
Cerebral Palsy, Intraventricular Hemorrhage
Beneficial Effects of Antenatal Magnesium Sulfate (BEAM Trial)
As many more premature infants survive, the numbers of these infants with health problems increases. The rate of cerebral palsy (CP) in extremely premature infants is approximately 20%.
- Conditions
- Cerebral Palsy, Intraventricular Hemorrhage, Periventricular Leukomalacia, Pulmonary Edema
- Trial name
- BEAM (NCT00014989)
- Testing
- magnesium sulfate
- Where
- 17 sites in United States
- Volunteers
- 2,136 people
- Sponsor
- The George Washington University Biostatistics Center
Shortness of Breath, Chest Pain
Checklists Resuscitation Emergency Department
The study will systematically evaluate how an emergency manual-a collection of checklists and fact sheets-affects the performance of resuscitation teams during the management of priority one patients in an emergency department.
- Conditions
- Shortness of Breath, Chest Pain, Abdominal Pain, Altered Mental Status
- Trial name
- NCT05649891
- Testing
- Emergency Manual
- Volunteers
- 2,000 people
- Sponsor
- Region Skane
Emergence Agitation, Anesthetics
The Effect of Low Flow Anesthesia on Postoperative Emergence Agitation in Rhinoplasty
Emergence agitation, defined as restlessness, disorientation, arousal, and/or inconsolable crying, is a common phenomenon seen in the early phase of recovery from general anesthesia; this may cause respiratory depression, nausea…
- Conditions
- Emergence Agitation, Anesthetics, Rhinoplasty
- Trial name
- NCT05601674
- Testing
- : Conventional flow Anesthesia, Low Flow Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Inonu University
Embolic Stroke, Postoperative Cognitive Dysfunction
Perfusion Pressure Cerebral Infarction Trial (PPCI)
STUDY HYPOTHESIS In cardiac surgery the volume of perioperative cerebral infarctions can be reduced by increasing mean arterial pressure (MAP) during the cardiopulmonary bypass procedure.
- Trial name
- PPCI (NCT02185885)
- Testing
- Increased bloodpressure during CPB.
- Where
- Denmark
- Volunteers
- 197 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Care Acceptor, Health, Pain, Postoperative
Effect of Comedy Therapy on Pain and Anxiety Levels After Ureterorenoscopy
The aim is to determine the effect of comedy therapy on pain and anxiety levels in patients after Uretero-Renoscopy (URS) surgery.
- Conditions
- Care Acceptor, Health, Pain, Postoperative, Anxiety Postoperative, Surgery
- Trial name
- NCT06805058
- Testing
- comedy therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Bitlis Eren University
Cystitis, Interstitial
Pilot Study Evaluating the Efficacy of Certolizumab Pegol for Interstitial Cystitis
A Randomized, Double-blind, Placebo Controlled Trial of Certolizumab Pegol in Women with Refractory Interstitial Cystitis/Bladder Pain Syndrome
- Trial name
- NCT02497976
- Testing
- Certolizumab pegol
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- ICStudy, LLC
Adenomyosis, Heavy Uterine Bleeding
Effect of Ulipristal Acetate on Bleeding Patterns and Dysmenorrhea in Women With Adenomyosis
Adenomyosis affects approximately 21% of symptomatic women who present to gynecology clinics. The disease is characterized by heavy bleeding and pain during periods.
- Conditions
- Adenomyosis, Heavy Uterine Bleeding, Dysmenorrhea
- Trial name
- NCT03325868
- Testing
- Ulipristal Acetate
- Where
- United States
- Sponsor
- Vanderbilt University Medical Center
Postoperative Pain
OFA - Opioid Free Anesthesia
Opioids have been used for analgesia since many years, but despite potent analgesia they are also associated to side effects, including opioid induced Hyperalgesia (OIH).
- Trial name
- OFA (NCT03124082)
- Testing
- Remifentanil, Ketamine, Lidocaine
- Where
- Italy
- Volunteers
- 64 people
- Sponsor
- University of Parma
Postoperative Pain
Peripheral Nerve Blocks for Major Lower Extremity Amputations
This study will be a double-blinded randomized controlled trial analyzing all patients who will undergo major lower extremity amputations by the vascular surgery service at University of California, San Francisco (UCSF) Fresno…
- Trial name
- NCT03174782
- Testing
- Bupivacaine, Saline Solution
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Pain, Postoperative
Survey of Postoperative Pain and Pain Management in Norwegian Hospitals
The study is a national survey of pain and pain management to surgical patients in Norwegian Hospitals. Data on pain management are gathered from patient records and data on pain and patient satisfaction are gathered as patients'…
- Trial name
- NCT01413724
- Volunteers
- 300 people
- Sponsor
- Norwegian University of Science and Technology
Pain, Postoperative
The Efficacy and Safety of NALDEBAIN for the Treatment of Post-Laparotomy Surgery
The primary objective of this study is to determine the safety and efficacy of single doses of intramuscular NALDEBAIN on patients scheduled to undergo elective laparotomy.
- Trial name
- NCT03296488
- Testing
- Nalbuphine Sebacate, Fentanyl Citrate
- Where
- Taiwan
- Volunteers
- 110 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
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