Clinical trials: Neurologic Complications
Postoperative Pain
Dexamethasone Twice for Pain Treatment of Total Knee Arthroplasty
Dexamethasone twice for pain treatment after total knee arthroplasty - A Placebo-controlled, randomised, parallel 3-group multicentre trial of one and two doses of dexamethasone for postoperative treatment
- Trial name
- DEX-2-TKA (NCT03506789)
- Testing
- Dexamethasone
- Where
- 5 sites in Denmark
- Volunteers
- 485 people
- Sponsor
- Naestved Hospital
Complications of Surgical Procedure, Neurogenic Bladder
Complications of Enterocystoplasty in Children
The goal of this observational study is to describe the complications in participants who underwent enterocystoplasty in childhood.
- Conditions
- Complications of Surgical Procedure, Neurogenic Bladder, Spina Bifida, Child, Only
- Trial name
- AVPED (NCT05840874)
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Dr Christelle DESTINVAL
Breast Cancer, Mastectomy
A Study to Reduce Persistent Post-mastectomy Pain Using Opioid-free Anesthesia
In 230 patients undergoing mastectomy, the investigators will compare opioid-free anesthesia (OFA) versus conventional opioid-based anesthesia in terms of chronic pain.
- Conditions
- Breast Cancer, Mastectomy, Pain, Chronic, Pain, Post Operative
- Trial name
- RELIEF (NCT05146778)
- Testing
- Opioid-free anesthesia, Conventional opioid-based anesthesia
- Where
- South Korea
- Volunteers
- 230 people
- Sponsor
- Gangnam Severance Hospital
Esophageal Cancer, Nutrition Aspect of Cancer
Assessing Timing of Enteral Feeding Support in Esophageal Cancer Patients on Muscle functTion and Survival
The surgical stress of an esophagectomy causes a detrimental impact on the physiological response of the body. In this perspective, one could question whether the current feeding regimens of starting early nutritional support at…
- Conditions
- Esophageal Cancer, Nutrition Aspect of Cancer, Postoperative Complications, Muscle Weakness
- Trial name
- EFECTS (NCT03676478)
- Testing
- delayed start enteral support @ POD5
- Where
- Belgium
- Volunteers
- 239 people
- Sponsor
- University Hospital, Gasthuisberg
Deviated Nasal Septum
Perioperative Administration of Pregabalin for Pain After Septoplasty
Pregabalin is used for the treatment of neuropathic pain and has shown analgesic efficacy in postoperative pain. The aim of this randomized, double-blinded, placebo-controlled trial was to investigate the efficacy and safety of…
- Trial name
- NCT01370915
- Testing
- Pregabalin (Lyrica)
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Samsung Medical Center
Pain, Postoperative, Abdominoplasty
Quadratus Lumborum Block for Abdominoplasty
Double blinded, randomized, controlled, phase IV intervention trial. Both groups will receive a quadratus lumborum Block (QL), using ropivacaine 3.75 mg/mL in the intervention group, and sterile sodium chloride in the control…
- Trial name
- NCT02949778
- Testing
- QL-block, Ropivacaine, Sodium Chloride
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- Vestre Viken Hospital Trust
Post Operative Pain, Chronic Apical Periodontitis of Pulpal Origin
The Effect of Using Reciprocal Files Alone and With Different Files on Postoperative Pain
This study aims to investigate the effects of using the Wave One Gold file alone and in combination with different files on postoperative pain in patients with asymptomatic apical periodontitis.
- Trial name
- NCT06833515
- Testing
- one flare+wave one gold glider+wave one gold, wave one gold glider+wave one gold, wave one gold
- Where
- Turkey (Türkiye)
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Harran University
Tibial Fractures, Fibula Fracture
Effect of Palmitoylethanolamide on Reducing Opioid Consumption for Below Knee Fracture Fixation
Palmitoylethanolamide (PEA), a non-psychoactive cannabis compound derived from peanuts, egg yolks, and soybeans, is an Endogenous FA Amide produced in the body as a biological response and a repair mechanism in chronic…
- Conditions
- Tibial Fractures, Fibula Fracture, Knee Fracture
- Trial name
- NCT05317676
- Testing
- Palmitoylethanolamide
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Irvine
Non-Small Cell Lung Cancer
20-Fr Versus 24-Fr Chest Drains After Uniportal VATS Lobectomy for NSCLC
This randomized clinical trial compared two different chest drain sizes, 20 Fr and 24 Fr, in patients undergoing lung lobectomy for lung cancer.
- Trial name
- DRAIN2024 (NCT07827885)
- Testing
- 20-Fr Thoracic Drain, 24-Fr Thoracic Drain
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Fondazione Policlinico Universitario Campus Bio-Medico
Adrenal Cortical Cancer, Brain Cancer
Spectroscopy With Surface Coils and Decoupling
The purpose of this study is to obtain chemical information from part of your body without a biopsy. This is done using a technique called magnetic resonance spectroscopy (MRS) which is similar to magnetic resonance imaging (MRI)…
- Conditions
- Adrenal Cortical Cancer, Brain Cancer, Breast Cancer, CNS Cancer
- Trial name
- NCT00581815
- Testing
- Proton-decoupled 31P MRS at 1.5T, 1H Spectroscopy at 1.5T and 3T
- Where
- United States
- Volunteers
- 582 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Potassium, Decreased Level, Postsurgical Pain, Chronic
Serum Potassium as a Predictor of Clinical Outcomes in an Older Patient Cohort With Chronic Postsurgical Pain
Perioperative serum potassium in patients over 65 impacts recovery, quality of life and physical functioning. While perioperative serum potassium is an important preoperative risk factor for poor surgical outcomes in older…
- Trial name
- NCT05385640
- Testing
- NO intervention
- Where
- China
- Volunteers
- 3,088 people
- Sponsor
- Chinese PLA General Hospital
Opioid Use, Pain, Postoperative
SMS Education for Post-operative Pain
The purpose the research is to assess whether or not postoperative education and awareness about pain and opioid use through SMS text messages will reduce overall opioid utilization after common outpatient surgeries.
- Trial name
- NCT04039191
- Testing
- SMS education, SMS survey
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Cedars-Sinai Medical Center
Emergence Delirium
Effects of Remifentanil Infusion on Emergence Delirium After Dental Surgery in Children
In this study, the investigators tried to show the effect of remifentanil on emergence delirium caused by sevoflurane used in general anesthesia.We planned a retrospective study. We formed two groups of 80 participants.
- Trial name
- NCT04300374
- Testing
- The Paediatric Anaesthesia Emergence Delirium scale assesment which was recorded postoperatively
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Erzincan University
Emergence Delirium
Verbal Stimulation of Orientation on Emergence Agitation
The purpose of this study is to investigate whether information of the orientation such as time, place, and patient's own name can reduce emergence delirium after general anesthesia.
- Trial name
- NCT05105178
- Testing
- Giving orientation with headphones, Emergence as usual with headphones
- Where
- South Korea
- Volunteers
- 126 people
- Sponsor
- Seoul National University Hospital
Post Operative Pain
Peri Tonsillar Infiltration of Ketamine or Bupivacaine for Post Tonsillectomy Analgesia
Comparison between the analgesic effect of local infiltration of either Bupivacaine or ketamine in the peritonsillar area before the incision of tonsillectomy to achieve postoperative analgesia
- Trial name
- NCT05341323
- Testing
- Ketamine., Bupivacaine
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Sohag University
Head and Neck Cancer, Acute Pain
Perioperative Gabapentin Use In Head And Neck Mucosal Surgery Patients
Patient satisfaction with healthcare is increasingly being utilized as a metric to reflect provider and hospital quality of care.
- Conditions
- Head and Neck Cancer, Acute Pain, Postoperative Pain
- Trial name
- GABA (NCT02926573)
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 123 people
- Sponsor
- Washington University School of Medicine
Prostate Cancer
Postoperative Patient Comfort and Quality of Micturition in Suprapubic Tube vs. Transurethral Catheterization After RARP
The purpose of the study is to determine, whether the postoperative quality of micturition and continence can be improved depending on the urinary drainage catheter and retention after robot assisted radical prostatectomy.
- Trial name
- MPH (NCT02812173)
- Testing
- suprapubic tube ex 2 day, suprapubic tube ex 5 day, transurethral catheter ex 5 day
- Where
- Germany
- Volunteers
- 234 people
- Sponsor
- St. Antonius Hospital Gronau
Diabetic Neuropathies, Diabetes Mellitus, Type 2
A Study To Evaluate The Effect Of Topiramate On Clinical And Electrophysiological Parameters In Subjects With Diabetic Peripheral Polyneuropathy
The purpose of the study is to evaluate the effect of topiramate on clinical and electrophysiological parameters in patients with diabetic peripheral polyneuropathy.
- Conditions
- Diabetic Neuropathies, Diabetes Mellitus, Type 2, Polyneuropathies
- Trial name
- NCT00231673
- Testing
- Topiramate
- Volunteers
- 72 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Cardiac Arrest (CA), Post Cardiac Arrest Syndrome
TNF-α Antagonists Mitigate Systemic Inflammatory Response After Cardiac Arrest.
The investigators assessed the effect of TNF-α antagonism within 6 hours of return of spontaneous circulation on 30-day mortality in patients who remained comatose after cardiopulmonary resuscitation (CPR) following cardiac…
- Trial name
- NCT07176754
- Testing
- Infliximab
- Where
- China
- Volunteers
- 208 people
- Sponsor
- Peking University Third Hospital
Pain, Postoperative
Effects of Lavender Oil on Postoperative Pain, Sleep Quality and Mood
This project will evaluate the integration of lavender essential oil in surgical patients during the perioperative and postoperative phase of care. The study will assess patients' pain, sleep quality, and mood.
- Trial name
- NCT03093454
- Testing
- Lavender Essential Oil
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Scott Hollenbeck, MD
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