Clinical trials: Neurologic Complications
Postoperative Pain, Facial Swelling
Aescin-Based Herbal Extract (Reparil) for Postoperative Sequelae After Mandibular Third Molar Surgery
This randomized, single-blind, controlled clinical trial aims to evaluate the efficacy and safety of Aescin-based herbal extract (Reparil®) compared with Ibuprofen in managing postoperative sequelae following surgical removal of…
- Conditions
- Postoperative Pain, Facial Swelling, Trismus
- Trial name
- Reparil (NCT07244029)
- Testing
- Escin, Ibuprofen 400 mg
- Where
- Oman
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Oman Medical Speciality Board
Adenotonsillectomy, Children
Intranasal Dexmedetomidine-esketamine Administration and Postoperative Pain in Pediatric Patients
Postoperative pain after adenoid and tonsil surgery is significant, with approximately 75% of pediatric patients experiencing severe postoperative pain.
- Conditions
- Adenotonsillectomy, Children, Intranasal Administration, Dexmedetomidine
- Trial name
- NCT07479602
- Testing
- Intranasal dexmedetomidine-esketamine
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Peking University First Hospital
Robotic Colorectal Surgery, Erector Spine Plane Block
Analgesic Efficacy of Intertransverse Process Block Versus Erector Spinae Plane Block
This randomized clinical trial aims to evaluate and compare the analgesic efficacy of the Intertransverse Process Block (ITP) and the Erector Spinae Plane (ESP) block in patients undergoing Robotic Colorectal Surgery.
- Conditions
- Robotic Colorectal Surgery, Erector Spine Plane Block, Intertransverse Process Block, Postoperative Pain
- Trial name
- NCT07583602
- Testing
- Intertransverse Process Block (ITP), The Erector Spinae Plane Block (ESP)
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Antalya City Hospital
Fracture, Infection
A Geriatric Home Visit Program to Reduce Post-Hip Fracture Complications
The overall goal of the project is to reduce the incidence of post hip fracture morbidity and mortality by conducting geriatric fellow periodic home visits.The assessment will be multidisciplinary and will include assessments of…
- Conditions
- Fracture, Infection, Depression, Gait Instability
- Trial name
- NCT02058329
- Testing
- Home Visit
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Northwell Health
Acute Appendicitis
Laparoscopic-Assisted TAP Block VErsus Trocar-site Infiltration After Laparoscopic Appendectomy
This randomized controlled trial compared laparoscopic-assisted transversus abdominis plane (TAP) block with trocar-site local anesthetic infiltration for postoperative pain management in adult patients undergoing laparoscopic…
- Trial name
- NCT07849751
- Testing
- laparoscopic-assisted transversus abdominis plane block, trocar-site local anesthetic infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Stoma Closure, Postoperative Pain
Revised-Paravertebral Nerve Blocks for Enhanced Recovery After Stoma Closure
After stoma closure, pain remains an important problem affecting patient recovery. A revised paravertebral block (r-PVB) was developed as a single-shot, large-volume intercostal-space injection performed at the exposed…
- Conditions
- Stoma Closure, Postoperative Pain, Quality of Recovery
- Trial name
- r-PVB III (NCT07571902)
- Testing
- Revised-Paravertebral Nerve Block
- Volunteers
- 250 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Pain
Patient Controlled Analgesia Pharmacogenetic Study
The purpose of this research study is to identify factors and genes (the nucleic acid material that determines the makeup of the human body) that may be associated with acute and chronic post-surgical pain as well as develop…
- Trial name
- NCT01731873
- Where
- United States
- Volunteers
- 182 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Diabetic Nephropathies
Sympathetic Nervous System Inhibition for the Treatment of Diabetic Kidney Disease
The purpose of this study is to determine whether moxonidine is effective in reducing urine albumin levels in patients with diabetic kidney disease.
- Trial name
- NCT01094769
- Testing
- Moxonidine
- Where
- Australia
- Volunteers
- 48 people
- Sponsor
- Baker Heart and Diabetes Institute
Inguinal Hernia, Postoperative Pain
TENS for Pain and Sleep After Hernia Surgery
This study evaluates whether Transcutaneous Electrical Nerve Stimulation (TENS) improves postoperative pain and sleep quality in adults undergoing inguinal hernia surgery.
- Conditions
- Inguinal Hernia, Postoperative Pain, Sleep Disturbance
- Trial name
- TENS-HERNIA (NCT07319754)
- Testing
- Transcutaneous Electrical Nerve Stimulation (TENS), Standard Postoperative Care
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Nigde Omer Halisdemir University
Emergence Agitation
Comparison Between Propofol and Fentanyl for Prevention of Emergence Agitation in Children After Sevoflurane Anesthesia
The occurrence of emergence agitation (EA) in pediatric patients who have received sevoflurane anesthesia is a common postoperative problem.
- Trial name
- NCT01506622
- Testing
- Administration of propofol, Administration of fentanyl, Administration of saline
- Where
- South Korea
- Volunteers
- 222 people
- Sponsor
- Yonsei University
Postoperative Pain
Analgesic Efficacy of Intravenous Lidocaine and/or Ketamine
The aim of the present study is to evaluate the analgesic benefit of intravenous lidocaine and ketamine in the perioperative period of abdominal surgery.
- Trial name
- NCT01439399
- Testing
- Lidocaine,, Ketamine, association ketamine-lidocaine
- Where
- Switzerland
- Volunteers
- 52 people
- Sponsor
- University of Lausanne Hospitals
Pulpal Inflammation, Dental Caries
Effect of Different Heating Protocols of Resin Composites on Pulp Condition (Randomized Controlled Trial)
This randomized controlled clinical trial evaluates the effect of different resin composite preheating protocols on pulpal inflammation and postoperative pain.
- Conditions
- Pulpal Inflammation, Dental Caries, Postoperative Pain
- Trial name
- NCT07720999
- Testing
- Arm 1 only "VisCalor Thermoviscous Bulk-Fill Composite", Tetric EvoCeram Conventional Nanohybrid Composite (Preheated 55°C), Tetric EvoCeram Conventional Nanohybrid Composite (Room Temperature)
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Surgery, Anesthesia, Local
Block of the Sphenopalatine Nerve Ganglion for Postoperative Analgesia
Transsphenoidal surgery is considered safe and effective and is currently the procedure of choice for the removal of intrasellar lesions.
- Conditions
- Surgery, Anesthesia, Local, Postoperative Pain
- Trial name
- NCT04339231
- Testing
- sphenopalatine ganglion block
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Stroke, Swallowing Disorder
The Effects of Neuromuscular Electrical Stimulation on Swallowing Functions in Stroke Patients With Dysphagia
In our study, our aim is to evaluate the effect of neuromuscular electrical stimulation added to traditional dysphagia therapy in stroke patients with dysphagia, on functional oral intake status, dysphagia-related symptoms…
- Conditions
- Stroke, Swallowing Disorder, Dysphagia, Stroke, Complication
- Trial name
- NCT04421937
- Testing
- Procedure: Traditional Dysphagia Therapy (TDT), Procedure: Neuromuscular Electrical Stimulation with TDT
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Istanbul University
Chronic Postsurgical Pain
Vaginal or Laparoscopic Hysterectomy, Persistent Postsurgical Pain
Previous studies have shown that chronic pain after hysterectomy is common. The aim of this study is to investigate the incidence of chronic pain after vaginal or laparoscopic hysterectomy for benign reasons.
- Trial name
- NCT01537731
- Testing
- vaginal or laparoscopic hysterectomy
- Where
- Finland
- Volunteers
- 225 people
- Sponsor
- Tampere University Hospital
Pain, Postoperative
Preemptive Analgesia for Postoperative Pain Control for Dental Treatment Under General Anesthesia
The aim of this study was to compare the analgesic-treated children with analgesic prior to the treatment and to compare the postoperative analgesic needs of children undergoing dental treatment under general anesthesia.
- Trial name
- NCT03852602
- Testing
- Preemptive Analgesics, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Aydin Adnan Menderes University
Septic Shock, Delirium
Septic Shock and Delirium Because of rSO2 Abnormalities in Intensive Care Unit Patients (The SAD BRAIN Study)
Delirium in the ICU is a prevalent problem occurring in up to 80% of ICU patients. A potential cause of delirium in ICU patients could be cerebral hypoxia. Septic shock is associated with high rates of delirium.
- Conditions
- Septic Shock, Delirium, Renal Failure
- Trial name
- NCT01836302
- Testing
- Observation
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- University of Manitoba
Failed Back Surgery Syndrome
Spinal Cord Stimulation Frequency Study
The purpose of this study is to evaluate the role of frequency settings on spinal cord stimulation in the management of Failed Back Surgery Syndrome (SCS Frequency Study).
- Trial name
- NCT01750229
- Testing
- 1200 Hz, 3030 Hz, 5882 Hz
- Where
- United Kingdom
- Volunteers
- 53 people
- Sponsor
- MedtronicNeuro
Post Operative Pain, Acute, Post-Op Complication
Pigtail or Chest Tube Placement After Uniportal Video-assisted Thoracoscopic Surgery
This study aims to figure out how small-bore pigtail catheter or large-bore chest tube for postoperative drainage impact on analgesic efficacy and actually enhance recovery postoperatively.
- Conditions
- Post Operative Pain, Acute, Post-Op Complication, Opioid Use, Unspecified, ERAS
- Trial name
- NCT06050551
- Testing
- uniportal VATS
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Cheng-Kung University Hospital
Post Operative Pain
Preemptive Acetaminophen for Postoperative Pain Control Following Minimally Invasive Hysterectomy
This study is investigating whether administration of acetaminophen the day before surgery improves post operative pain following minimally invasive hysterectomy.
- Trial name
- NCT04360135
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
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