Clinical trials: Neurologic Complications
Postoperative Pain After a Total Knee Arthroplasty
Post-operative Analgesic Effect of Oral Nefopam
Primary knee arthroplasty by total prosthesis is a painful surgery, performed on patients with advanced gonarthrosis (stage III), thus already presenting hyperalgesia and hyperalgesia and allodynia.
- Trial name
- NefPO (NCT04576078)
- Testing
- Oral nefopam
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Hospices Civils de Lyon
Diabetic Polyneuropathy, Sleep Hygiene
The Effect of Sleep Hygiene Education on Sleep Quality and Quality of Life in Patients With Painful Diabetic Polyneuropathy
This randomized controlled study was designed to the effect of sleep hygiene education on sleep quality and quality of life in patients with painful diabetic polyneuropathy The study was conducted between January 2025 and January…
- Conditions
- Diabetic Polyneuropathy, Sleep Hygiene, Pain
- Trial name
- NCT07646743
- Testing
- sleep hygiene education, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Trakya University
Parkinson's Disease, Overactive Bladder
Anticholinergic Therapy for Overactive Bladder in Parkinson's Disease
The purpose of this research study is to investigate the cognitive (thinking, memory, knowledge, intelligence) side effects of two medications commonly used to treat overactive bladder (OAB) symptoms in veteran patients with…
- Trial name
- NCT00892450
- Testing
- Oxybutynin and darifenacin
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- US Department of Veterans Affairs
Chronic Apical Periodontitis
The Effect of Different Sodium Hypochlorite Concentrations and Activation Techniques on Postoperative Pain
The goal of this clinical trial was to evaluate the effect of different sodium hypochlorite (NaOCl) concentrations and irrigation activation techniques on the intensity of postoperative pain following single-visit root canal…
- Trial name
- NCT07033247
- Testing
- EDDY Sonic Activation System, Passive Ultrasonic Irrigation (PUI)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Cukurova University
Gait Disorders, Neurologic, Urinary Incontinence, Urge
Time to be Ready to Void: a New Tool to Assess the Time Needed to Perform Micturition in Multiple Sclerosis
The aim of the study is to create a specific test to assess the global time required to go to the toilet and to perform micturition, at the moment the patient decides to urinate in multiple sclerosis population, and to assess its…
- Conditions
- Gait Disorders, Neurologic, Urinary Incontinence, Urge, Multiple Sclerosis
- Trial name
- NCT04024085
- Testing
- completion of the test created Time to be Ready to Void
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Gérard Amarenco
Pain, Postoperative
Methadone Perception Survey Study
This is a cross-sectional survey study to describe the perception of methadone in various groups, caregivers of pediatric outpatient surgical patients, surgeons, and anesthesiologists.
- Trial name
- NCT07537608
- Testing
- Survey
- Where
- United States
- Volunteers
- 199 people
- Sponsor
- Ashley Smith
Pain, Postoperative, Ureter Stone
Local Anaesthetic and Steroid in the Ureter
Précis: Randomised control trial to evaluate safety and efficacy of intraluminal injection of high pH-high concentration of a long-acting local anesthetic and long-acting glucocorticoid in the ureter after ureteroscopy.
- Trial name
- LASTE (NCT03296189)
- Testing
- Levobupivacaine, Dexamethasone Sodium Phosphate
- Where
- Ireland
- Volunteers
- 150 people
- Sponsor
- The Adelaide and Meath Hospital, incorporating The National Children's Hospital
Postoperative Pain
Interscalene Versus Combined Infraclavicular-suprascapular Nerve Blocks
The aim of this trial is to compare the analgesic efficiency and hemi-diaphragmatic paralysis of the standard ultrasound-guided interscalene (ISB) brachial plexus block with the combined use of costoclavicular approach of…
- Trial name
- NCT03628950
- Testing
- ICSSB group, ISB group
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Fayoum University Hospital
Pain, Postoperative
Thoracic Paravertebral Block Using Ropivacaine and Dexmedetomidine
The hypothesis of the study is whether dexmedetomidine plus local anesthetic ropivacaine could extend the pain relieve time compared with only ropivacaine when thoracic paravertebral block is performed at the end of…
- Trial name
- NCT02814890
- Testing
- Video-assisted Pneumonectomy, Thoracic paravertebral block
- Where
- China
- Volunteers
- 65 people
- Sponsor
- Jianghui Xu
Hip Arthroplasty, Hip Fracture Surgeries
Sacral ESPB vs. PENG Block for Hip Hemiarthroplasty Analgesia
Sacral erector spinae plane block(S-ESPB) has been recently described. Case reports are showing that it is useful in various types of surgery.
- Conditions
- Hip Arthroplasty, Hip Fracture Surgeries, Femoral Neck Fractures, Postoperative Pain
- Trial name
- NCT07442721
- Testing
- Sacral erector spinae plane block, PENG block
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Fayoum University Hospital
Diabetic Polyneuropathy
A Study of CGRP Monoclonal Antibody to Treat Diabetic Neuropathy
The main purpose of this study is to compare the change in pain intensity during treatment with a CGRP monoclonal antibody (eptinezumab) compared with placebo treatment in patients with painful diabetic polyneuropathy (DPN).
- Trial name
- NCT05937152
- Testing
- Eptinezumab
- Where
- 3 sites in United States, Denmark
- Sponsor
- Mayo Clinic
Postoperative Pain
Massage After Surgery To Help Treat Post-Operative Pain
Postoperative pain is often undertreated. Although studies have demonstrated that many patients experience a substantial degree of unrelieved pain following operative procedures and that this pain can increase the incidence of…
- Trial name
- NCT00057148
- Testing
- massage treatment
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- US Department of Veterans Affairs
Parkinson's Disease, Overactive Bladder
Safety and Efficacy of Botulinum Toxin A for Treatment of Overactive Bladder in Parkinson's Disease
A randomized controlled trial is to be conducted to confirm the efficacy and safety of intramuscular injection of botulinum toxin in the treatment of Parkinson's bladder overactivity.
- Conditions
- Parkinson's Disease, Overactive Bladder, Onabotulinumtoxin A
- Trial name
- NCT05997043
- Testing
- oral anti-Parkinson drugs and injection of botulinum toxin, oral anti-Parkinson's drugs
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Zhujiang Hospital
Diabetic Polyneuropathy, Diabetes Mellitus, Type 2
Driving with Neuropathy
This study is a proof-of-concept randomised controlled trial (RCT). The goal of the study is to investigate the effectiveness of a feedback intervention to improve use of the accelerator pedal in patients driving with diabetes…
- Trial name
- NCT06739135
- Testing
- Visual feedback training
- Where
- United Kingdom
- Volunteers
- 115 people
- Sponsor
- Manchester Metropolitan University
Molar, Third, Postoperative Complications
The Use of Injectable-Platelet Rich Fibrin (i-PRF) in the Lower Third Molar Extraction
Lower third molar extraction is one of the most frequently performed surgical procedures in dentistry. Common sequelae, including pain, swelling and trismus, can severely affect patients' quality of life during the immediate…
- Trial name
- NCT06073535
- Testing
- Extraction of mandibular third molar, i-PRF
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Naples
Postoperative Pain, Video-Assisted Thoracoscopic Surgery
SPSIP Block vs SAP Block for Post-VATS Pain
Comparison of Superior Serratus Posterior Intercostal Plane Block and Serratus Anterior Plane Block for Pain Management Following Video-Assisted Thoracoscopic Surgery: A Prospective Observational Cohort Study Introduction…
- Trial name
- NCT07467291
- Testing
- Serratus Anterior Plane Block (SAPB) group, Serratus posterior superior intercostal plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Firat University
Rotator Cuff Tear
Clinical Research Study of the Benefits of BREG Polar Care Wave to Reduce Opioid Use by Patients Having Undergone Arthroscopic Rotator Cuff Repair Shoulder Surgery
The goal of this clinical trial is to compare effect of cold compression to standard of care in patients undergoing rotator cuff repair.
- Trial name
- CCROUT (NCT07455474)
- Testing
- Breg Polar Care Wave Cold Compression Device
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- University of Nevada, Reno
Postoperative Complications, Psychosomatic Disorder
Development of Machine Learning Models for the Prediction of Complications After Colonic, Colorectal and Small Intestine Anastomosis in Psychiatric and Non-psychiatric Patient Collectives (P-Study)
Our study aims to lay the basis for a predictive modeling service for postoperative complications and prolonged hospital stay in patients suffering from psychiatric diseases undergoing colorectal surgery.
- Conditions
- Postoperative Complications, Psychosomatic Disorder, Psychiatric Disorder, Cancer
- Trial name
- NCT05257863
- Where
- Switzerland
- Volunteers
- 10,000 people
- Sponsor
- Dr. Med Anas Taha
Postoperative Pain
Protracted Mixture of Local Anesthetics for Major Foot and Ankle Surgery
To extend the duration of peripheral nerve blockade after major foot and ankle surgery the investigators randomize the postoperative treatment with either perineurial sciatic nerve blocks with 0.5% Bupivacaine-Epinephrine with or…
- Trial name
- NCT02526199
- Testing
- Bupivacaine, Epinephrine, Dexamethasone
- Where
- Denmark
- Volunteers
- 56 people
- Sponsor
- Rasmus Wulff Hauritz
Postoperative Pain
Ultrasound Guided Bilateral Erector Spinae Plane Block in Retropubic Radical Prostatectomy
This study will define the postoperative analgesic effect of ESP block via amount of patient-controlled analgesia (PCA) and postoperative analgesic consumption (such as routinely and rescue analgesics) and compare the control…
- Trial name
- NCT03413163
- Testing
- Ultrasound guided erector spinae plane block, Standard Pain Followup and Monitorization
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Maltepe University
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