Clinical trials: Neurologic Disorders
Body Mass Index Quantitative Trait Locus 5 Disorder, Tangier Disease
Effect of High Protein Diet on Adiponectin and Inflammation Among Overweight and Obese Children
The investigators aimed to determine the effects of HP diet on adiponectin and inflammatory factors among overweight and obese children.
- Trial name
- NCT01886495
- Testing
- nutrition intervention
- Where
- Iran
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Myofascial Pain Syndromes, Low Back Pain
Radial Extracorporeal Shock Wave Treatment (rESWT) of Myofascial Pain Syndrome in Low Back Pain
The purpose of this study is to evaluate the efficacy of treatment of radial shockwave in myofascial pain syndrome in the lumbar region compared to placebo through questionnaires and imaging exams.
- Conditions
- Myofascial Pain Syndromes, Low Back Pain, Lumbago
- Trial name
- NCT01835795
- Testing
- Swiss DolorClast® CLASSIC applicator
- Where
- Brazil
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Musculoskeletal Pain
Transcultural Adaptation and Validation to Spanish of the OSPRO Questionnaires
Clinical guidelines for managing musculoskeletal pain recommend first, assessing and identifying any signs of severe physical conditions (i.e."red flags") and then, asessing the psychosocial prognostic factors of poor outcomes…
- Trial name
- SpanishOSPRO (NCT05869695)
- Testing
- OSPRO-ROS Questionnaire, OSPRO-YF Questionnaire
- Where
- 2 sites in Spain
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Subjective Sleep Quality, Objective Sleep Quality
Effect of B. Longum 1714™ on Sleep Quality
The aim of this study is to evaluate the effect of supplementation with the B. longum 1714™ strain on subjective and objective sleep quality in healthy participants.
- Trial name
- NCT04167475
- Testing
- Probiotic capsule
- Where
- Ireland
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- PrecisionBiotics Group Ltd.
Diabetic Neuropathy
Vitamin D Treatment for Painful Diabetic Neuropathy
The main objective of the study is to assess the effect of vitamin D treatment on painful diabetic neuropathy in Pakistan. This is a prospective study of diabetic patients with a DN score ≥ 4, administered a single dose of…
- Trial name
- NCT02737423
- Testing
- cholecalciferol
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Baqai Institute of Diabetology and Endocrinology
Parkinson Disease, Neurodegenerative Diseases
Mobile Parkinson Observatory for Worldwide, Evidence-based Research (mPower)
The purpose of this study is to understand variation in the symptoms of Parkinson disease. This study uses an iPhone app to record these symptoms through questionnaires and sensors.
- Conditions
- Parkinson Disease, Neurodegenerative Diseases, Movement Disorders, Central Nervous System Diseases
- Trial name
- mPower (NCT02696603)
- Testing
- Participant self-assessment surveys, Phonation, Gait and balance
- Where
- United States
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Sage Bionetworks
Sleep Quality
Understanding Physiology During Float-REST and the Consequential Effects on Subjective and Objective Recovery
The objective of this research study is to assess how the implementation of various modern strategies for augmented recovery and physiological monitoring via wearable biotechnologies and subjective measurements affect sleep…
- Trial name
- NCT04415970
- Testing
- Flotation therapy sensory deprivation tank, Sleep Pod
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- West Virginia University
Autoimmune Diseases, Relapsing Multiple Sclerosis
Fecal Microbial Transplantation in Relapsing Multiple Sclerosis Patients
The proposed randomized, open label, with treat as usual control group (standard treatment or any disease modifying drugs), crossover phase II study will be conducted in 40 patients (n=20 per group) with the relapsing forms of…
- Trial name
- NCT03183869
- Testing
- Fecal microbiota
- Where
- Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Sleep Apnea, Obstructives, Sleep Apnea Central
Development of a Torso Patch Sensor (C-TraQ) as a Companion Device to a Fingertip Sensor (TipTraQ) for Direct Monitoring of Respiratory Effort
The existing PranaQ system utilizes a fingertip sensor that captures PPG(Photoplethysmography) and accelerometer data, and its clinical validation is well-established.
- Trial name
- NCT07744854
- Where
- Taiwan
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- PranaQ Pte. Ltd.
Peripheral Neuropathy
Evaluation of Nerve Ultrasound in Detecting Clinical and Subclinical Peripheral Neuropathy in Children and Adolescents With Type 1 Diabetes Mellitus
Aim of study: To evaluate accuracy of nerve ultrasound in detecting clinical and subclinical peripheral neuropathy in children and adolescents diagnosed with type 1 diabetes melitus .
- Trial name
- NCT06187129
- Testing
- nerve ultrasound
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Esraa Hosny Dahy
Peripheral Vestibular Disorder, Benign Paroxysmal Positional Vertigo
Effect of Peripheral Vestibular Disease Location on Outcomes Following Home-based Virtual Reality Vestibular Therapy
This parallel-group randomized controlled trial aims to determine if the location of the lesion(s) in the vestibular system (unilateral versus bilateral, lateral semi-circular canal versus otolith) impacts the effectiveness of…
- Conditions
- Peripheral Vestibular Disorder, Benign Paroxysmal Positional Vertigo, Meniere Disease, Vestibular Neuritis
- Trial name
- VR-PVD-RCT (NCT05424302)
- Testing
- Standard Vestibular Rehabilitation with Adjunct At Home Virtual Reality Vestibular Rehabilitation, Standard Vestibular Rehabilitation with Adjunct Auditory Intervention
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Nicotine Withdrawal, Marijuana Dependence
Medications Development for the Treatment of Cannabis Related Disorders
The primary objective of this application is to test the neurobehavioral mechanisms and effects of aprepitant as a new cessation agent for cannabis, tobacco or both.
- Conditions
- Nicotine Withdrawal, Marijuana Dependence, Cannabis Dependence, Nicotine Dependence
- Trial name
- MTC (NCT01204723)
- Testing
- Active Aprepitant
- Where
- 2 sites in United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Cardiovascular Disease, Stroke
Heart Outcomes Prevention Evaluation-3
Heart disease and stroke are major causes of death and disability worldwide and are largely preventable. Cholesterol and blood pressure are major cardiovascular risk factors.
- Trial name
- HOPE-3 (NCT00468923)
- Testing
- Candesartan/HCT, Rosuvastatin
- Where
- Canada
- Volunteers
- 12,705 people, healthy volunteers welcome
- Sponsor
- Population Health Research Institute
Delirium
Prophylactic Olanzapine Versus Placebo for Prevention of Postoperative Delirium After Joint Replacement Surgery
In this study we wanted to determine if perioperative administration of olanzapine prior to knee or hip replacement surgery in high risk patients would prevent the onset of postoperative delirium.
- Trial name
- NCT00699946
- Testing
- olanzapine
- Where
- United States
- Volunteers
- 495 people, healthy volunteers welcome
- Sponsor
- The New England Baptist Hospital
Chronic Migraine; Multiple Sclerosis; Motoneuron Disease
Feasibility and Effectiveness of a Mindfulness Program Delivered by Web to Patients During Hospitalization and Caregivers.
Hospitalization is often a traumatic event so stressful for the life of patients. Isolation, loneliness, worries about clinical examinations, results from examinations and final diagnosis, uncertainty about the future are the…
- Trial name
- KIMPO (NCT05623254)
- Testing
- no comparator - TAU (Treatment-as-usual)
- Where
- Italy
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Sarcopenia, High Blood Pressure
The Impact of a Resistance Training Intervention on Blood Pressure Control in Older Adults With Sarcopenia
Current prevention and treatment of high blood pressure (BP) in sarcopenia, by non-pharmacological approaches remain limited and are far from optimal.
- Conditions
- Sarcopenia, High Blood Pressure, Hypertension
- Trial name
- INERTIA (NCT04255745)
- Testing
- progressive resistance training
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Shoulder Pain, Healthy Adult
Supraspinatus Tendon Acute Effects After Two Exercise Exposures: a Crossover Randomized Trial.
The purpose of this study is to understand acute tendon changes after two exercise programs. We will invite individuals with and without shoulder pain to participate in this study.
- Trial name
- NCT07489937
- Testing
- Isotonic exercise program, Plyometric exercise program
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Florida
Tetanus, Poliomyelitis
Immunogenicity and Safety Study of GSK Biologicals' Infanrix-IPV+Hib™ Vaccine
The purpose of the study is to evaluate the immunogenicity and reactogenicity of Infanrix-IPV/Hib™ vaccine when administered to healthy Chinese infants at 2, 3 and 4 or 3, 4 and 5 months of age.
- Conditions
- Tetanus, Poliomyelitis, Acellular Pertussis, Diphtheria
- Trial name
- NCT01086423
- Testing
- Infanrix-IPV/Hib™, Infanrix Hib™, Poliorix™
- Where
- 2 sites in China
- Volunteers
- 985 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Parkinson's Disease, Restless Leg Syndrome
A Single Dose, 2-Period, 2-Treatment, 2-Way Crossover Bioequivalency Study of Ropinirole 0.25 mg Tablets Und Fasted Conditions
The objective of this study was to assess the single dose bioequivalence of Roxane's Ropinirole Tablets, 0.25 mg to ReQuip Tablets, 0.25 mg (GlaxoSmithKline) under fasting conditions using a single-dose, randomized, 2-treatment…
- Trial name
- NCT00673088
- Testing
- Ropinirole Hydrochloride
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Roxane Laboratories
Brain Trauma
Magnetic Resonance (MR) Spectroscopy and Diffusion Tensor Imaging in Determining Brain Injury and Subsequent Clinical Outcome in Patients of Moderate Brain Trauma
The purpose of this study is to use magnetic resonance spectroscopy (MRS) and diffusion tensor imaging (DTI) to assess for traumatic brain injury and determine if there is any correlation of these findings to clinical outcome.
- Trial name
- NCT00760903
- Testing
- Conventional MRI of the brain, MR spectroscopy (MRS), MR Diffusion Tensor Imaging (DTI)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Michigan
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.