Clinical trials: Neurologic Findings
Hearing Loss
Littlears Auditory Questionnaire: Validation Study in CI Children
The LittlEARS Auditory Questionnaire is designed to assess the development of the auditory behavior in children during the first two (hearing) years.
- Trial name
- LittlEars (NCT00785707)
- Where
- 5 sites in United States
- Volunteers
- 31 people
- Sponsor
- Med-El Corporation
Sarcopenia
Nutritional Intervention for Age-related Muscular Function and Strength Losses-Study 2
Men and women lose muscle mass and strength with age. Loss of muscle mass and strength is accompanied by a loss of muscle function which can lead to diminished quality of life and more importantly can lead to serious fall…
- Trial name
- NCT02043171
- Testing
- HMB plus Vitamin D, Non-Exercise, Exercise
- Where
- United States
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Metabolic Technologies Inc.
Alzheimer's Disease Psychosis
ACP-204 in Adults With Alzheimer's Disease Psychosis Open Label Extension Study
This 52-week, open-label extension study is to evaluate the long-term safety and tolerability of ACP-204 in subjects with ADP.
- Trial name
- NCT06194799
- Testing
- ACP-204
- Where
- 78 sites in United States, Brazil and 10 more
- Volunteers
- 752 people
- Sponsor
- ACADIA Pharmaceuticals Inc.
Pain
Bioequivalence and Adhesion Comparison of Buprenorphine Patches
To compare a 2nd generation Buprenorphine Transdermal System (BTDS) patch with a marketed 1st generation BTDS patch to confirm that the two are bioequivalent (deliver the same amount of drug) and that they equally both stick to…
- Trial name
- NCT02268422
- Testing
- Buprenorphine
- Where
- 2 sites in United Kingdom
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Mundipharma Research Limited
Muscle Recovery, Muscle Soreness
Accelerating Post-exercise Muscle Glycogen Resynthesis in Humans: Impact of Combined Nutrient Intake and Intermittent Pneumatic Compression or Heat Therapy
To determine if modalities designed to improve blood flow combined with post-exercise nutrient intake will improve replenishment of muscle glycogen better than nutrient intake alone.
- Conditions
- Muscle Recovery, Muscle Soreness, Glycogen Depletion
- Trial name
- NCT04371237
- Testing
- Compression sleeve, Heat therapy, Glycogen-depleting exercise session
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Postoperative Pain
Phase 3 Herniorrhaphy Study for Postoperative Analgesia (EPOCH 2)
This is a Phase 3, randomized, double-blind, saline placebo- and active-controlled, multicenter study to evaluate the analgesic efficacy and safety of HTX 011 administered via local administration into the surgical site in…
- Trial name
- NCT03237481
- Testing
- HTX-011, Bupivacaine HCl, Luer-lock applicator
- Where
- 24 sites in United States, Belgium
- Volunteers
- 418 people
- Sponsor
- Heron Therapeutics
Sensitivity in Esophagus
Esophageal Hypersensitivity Study in Patients With Gastroesophageal Reflux Disease (GERD)
The purpose of the study is to compare sensitivity of visceral pain in the esophagus using different pain stimuli.
- Trial name
- NCT01019928
- Testing
- AZD1386
- Where
- 2 sites in Denmark, Sweden
- Volunteers
- 14 people
- Sponsor
- AstraZeneca
Chest Pain
Evaluation of Synthesized 18-Lead ECG in the Emergency Department
This study, sponsored by Nihon Kohden, aims to determine the sensitivity and specificity of synthesized 18-lead electrocardiogram (ECG) in the diagnosis of posterior-lateral and/or right-ventricular ischemia, using actual 18-lead…
- Trial name
- NCT03426436
- Testing
- Two consecutive 15-lead ECGs
- Where
- 2 sites in United States
- Volunteers
- 314 people
- Sponsor
- Nihon Kohden
Pain
Study Evaluating Ibuprofen 600 mg Extended Release (ER) For Dental Pain
The purpose of this study is to assess the efficacy and safety of a single dose of an ibuprofen 600 mg extended release formulation in post-operative dental pain.
- Trial name
- NCT00913627
- Testing
- ibuprofen, naproxen
- Where
- United States
- Volunteers
- 196 people
- Sponsor
- Pfizer
Angina Pectoris
Neurostimulation to Treat Refractory Angina Pectoris Pain
The therapy under investigation involves an implanted Medtronic neurostimulation system to relieve symptoms of angina pectoris pain.
- Trial name
- STARTSTIM (NCT00200070)
- Testing
- Spinal Cord Stimulation
- Where
- 8 sites in United States, Canada
- Volunteers
- 228 people
- Sponsor
- MedtronicNeuro
Post-stroke Aphasia
Neurostimulation for the Treatment of Post-Stroke Aphasia
The aim of the trial is to determine whether 75Hz transcranial alternating current stimulation (tACS) synchronized with therapeutic linguistic tasks is an effective form of therapy for post-stroke aphasia.
- Trial name
- NCT05194566
- Testing
- tACS
- Where
- 2 sites in United States
- Volunteers
- 64 people
- Sponsor
- QVITI S.A.
Chronic Low Back Pain
Efficacy and Safety of Hydrocodone Bitartrate (HYD) in Subjects With Moderate to Severe Chronic Low Back Pain
The primary objective of this study is to evaluate the analgesic efficacy and safety of HYD tablets 20 to 120 mg once-daily dose compared to placebo in subjects with moderate to severe chronic low back pain uncontrolled by their…
- Trial name
- NCT01452529
- Testing
- Hydrocodone bitartrate q24h film-coated tablets
- Where
- 102 sites in United States
- Volunteers
- 905 people
- Sponsor
- Purdue Pharma LP
Dizziness, Nausea
Efficacy of a Transcranial Vibrating System for Mitigation of Migraine Associated Vertigo
Vertigo is among the most common symptoms associated with migraine and affects 26.5% of migraine sufferers, leading to a dramatic impact in life limiting even the most simple activities.
- Conditions
- Dizziness, Nausea, Headache, Confusion
- Trial name
- NCT03886012
- Testing
- Otoband
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Otolith Labs
ADHD, Hyperactivity
Treatment With Cannabis Oil Containing CBD, THC, CBDV or CBG vs. Placebo of Persons With ADHD
ADHD is the most frequent neuro-developmental disorder in childhood and often continues into adolescence and adulthood. Indicated drug treatments for ADHD fall into 2 categories: stimulants (such as methylphenidate and…
- Conditions
- ADHD, Hyperactivity, Attention Deficit
- Trial name
- NCT05219370
- Testing
- Cannabis oil
- Where
- Israel
- Volunteers
- 8 people
- Sponsor
- Brlev Agricultural Crops Ltd
Coronary Artery Disease, Angina Pectoris
An Evaluation of Rigid Sternal Fixation in Supporting Bone Healing and Improving Postoperative Recovery
The primary objective of this study is to evaluate sternal bone healing following a full median sternotomy versus standard of care for sternal closure with wire cerclage.
- Conditions
- Coronary Artery Disease, Angina Pectoris, Cardiac Valve Disease
- Trial name
- SB (NCT01783483)
- Testing
- SternaLock Blue closure system, Suture Wire
- Where
- 12 sites in United States
- Volunteers
- 236 people
- Sponsor
- Zimmer Biomet
Angina Pectoris, Coronary Heart Disease
Evaluate the Efficacy and Safety of MUSK Pill on Coronary Microvascular Dysfunction
Objective to evaluate the effect of Shexiang Baoxin Pill on myocardial ischemia in patients with coronary microvascular dysfunction (non obstructive coronary heart disease) through a randomized, double-blind, placebo-controlled…
- Conditions
- Angina Pectoris, Coronary Heart Disease, X Syndrome, Angina, Non Obstructive Coronary Artery Disease
- Trial name
- NCT04984954
- Testing
- MUSK pill
- Where
- China
- Volunteers
- 264 people
- Sponsor
- Shanghai Hutchison Pharmaceuticals Limited
Chronic Pain, Insomnia
The Efficacy of CALPXT96™in Improving Sleep Quality in Patients With Chronic Non-cancer Pain
California Poppy has been traditionally used in Herbal Medicine as an analgesic, mild sedative and/or sleep aid. However there are no human clinical trial data to support its use.
- Trial name
- CALPXT96 (NCT02232256)
- Testing
- CALPXT96
- Where
- Canada
- Sponsor
- 9305-9954 Quebec Inc
Pain
Efficacy and Safety of Ralfinamide in Patients With Chronic Neuropathic Low Back Pain
The aim of the study is to determine if an experimental drug, ralfinamide, relieves your neuropathic low back pain, and if it demonstrates superiority to placebo, a "dummy" or sugar pill that contains no active medication.
- Trial name
- NCT01019824
- Testing
- Ralfinamide
- Where
- United Kingdom
- Volunteers
- 411 people
- Sponsor
- Newron Pharmaceuticals SPA
Pain
Omnitram Pharmacokinetic Study In Healthy Volunteers
The purpose of this study is to compare the safety, pharmacokinetic properties (the absorption, distribution and excretion), and analgesic activity of Omnitram (10 mg tablets), Tramadol (Ultram, 50 mg tablet) following oral…
- Trial name
- NCT02205554
- Testing
- Omnitram, Tramadol
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Syntrix Biosystems, Inc.
Acute Postoperative Pain, Dental Pain
A Study of CYT-1010 in Healthy Volunteers and Participants With Acute Pain After Third Molar Extraction
The primary objective of this trial is to assess the safety and tolerability of single, ascending doses of CYT-1010 in healthy male and female volunteers and in the treatment of acute postoperative pain after third molar…
- Trial name
- NCT07905105
- Testing
- CYT-1010
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Cytogel Pharma, LLC
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