Clinical trials: Neurologic Findings
Fibromyalgia, Sarcopenia
Determination of Metabolomic Profile Differences in Possible Sarcopenia Accompanying Fibromyalgia Syndrome in Women
The goal of this observational study is to determine the serum metabolome profile differences in the presence of possible sarcopenia in patients with fibromyalgia and to compare them with healthy individuals.
- Trial name
- NCT07381348
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Inguinal Hernia, Postoperative Pain
Comparison of Lornoxicam and Paracetamol for Pre-emptive Intravenous Analgesia for Elective Inguinal Hernia Repair
The purpose of this study is to determine whether lornoxicam or paracetamol is more effective in providing pre-emptive analgesia for adult patients undergoing elective unilateral inguinal hernia repair under general anesthesia.
- Trial name
- NCT01069055
- Testing
- Sterile Saline, Intravenous lornoxicam, Intravenous paracetamol
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Diskapi Teaching and Research Hospital
Hearing Loss, Sensorineural, Cystic Fibrosis
A Study of Web and Tablet-based Interactive Audiometry in Adults With CF
Adults with CF regularly receive anti-infective therapy that can result in impaired hearing. Recent studies have identified that up to 50% of adults with CF have hearing loss with resulting significant impact on quality of life.
- Trial name
- NCT04400955
- Testing
- Audiometry tablet diagnostic tool and web-based test
- Where
- United Kingdom
- Volunteers
- 156 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Stroke
A Study of the Efficacy and Safety of Alteplase in Participants With Mild Stroke
PRISMS is a double-blind, multicenter, randomized, Phase IIIb study to evaluate the efficacy and safety of intravenous (IV) alteplase in participants with mild acute ischemic strokes that do not appear to be clearly disabling.
- Trial name
- PRISMS (NCT02072226)
- Testing
- Alteplase, Aspirin
- Where
- 88 sites in United States
- Volunteers
- 313 people
- Sponsor
- Genentech, Inc.
Sleep Wake Disorders
Testing Methods to Increase the Frequency of Lucid Dreaming
This study investigates the impact of lucid dreaming on individuals and explores methods to increase the likelihood of inducing lucid dreams intentionally.
- Trial name
- RRF (NCT06440226)
- Testing
- Eye Movement Technique, Memory Recall of Previous Night's Thoughts, Recall of Previous Lucid Dreams
- Where
- United Kingdom
- Volunteers
- 101 people
- Sponsor
- Abdulraheem Mohamed Gouda
Spinal Cord Injuries, Muscle Spasticity
Cyproheptadine and Chlorpromazine Effects on Spasticity
The main goal of this research is to understand the neuronal mechanisms that mediate the development of spasticity and motor dysfunction after spinal cord injury.
- Trial name
- NCT01509885
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Secondary Hyperalgesia, Inflammation
The Effect of Hyperbaric Oxygen Therapy on Inflammatory Parameters Induced by a Heat Injury Model
Hyperbaric oxygen may reduce neurophatic pain and promote wound healing. Established anti inflammatory effects of HBO may contribute to this effect.
- Trial name
- HBO-SHA (NCT02397343)
- Testing
- Hyperbaric oxygen
- Where
- Denmark
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Acute Pain
Nefopam/Paracetamol Fixed Dose Combination in Acute Pain After Impacted Third Molar Extraction
This study aims to evaluate the analgesic efficacy of single and multiple doses of a new fixed dose combination of nefopam hydrochloride 30 mg and paracetamol 500mg taken orally in comparison to each single component.
- Trial name
- NCT04622735
- Testing
- nefopam hydrochloride 30mg / paracetamol 500mg X2, Paracetamol 500 Mg Oral Tablet X2, Nefopam HCl 30 MG Oral Tablet X2
- Where
- 19 sites in Belgium, France and 3 more
- Volunteers
- 321 people
- Sponsor
- Unither Pharmaceuticals, France
Post Operative Pain, Spine Surgery
Effects of Continuous ESP Catheters on Recovery, Pain and Opioid Consumption After Multilevel Spine Surgery
Single-shot erector spinae plane (ESP) blocks (ESPB) are emerging as an intervention to improve pain and minimize opioid consumption after lumbar spine surgery.
- Trial name
- NCT05494125
- Testing
- Ropivacaine
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Chronic Pain, Spinal Cord Injuries
Improving Functioning in Persons With Chronic Pain Post-SCI Through Virtual Classroom Education
Chronic pain (pain that is that is present for a long period of time) is very common among people with spinal cord injury (SCI).
- Trial name
- NCT02561676
- Testing
- Education Program Type 1, Education Program Type 2
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Kessler Foundation
Vaginal Packing Following Laparoscopic Sacrocolpopexy, Pelvic Organ Prolapse
Vaginal Packing After Laparoscopic Sacrocolpopexy
Vaginal packing is used routinely following vaginal reconstructive surgery, however, no recommendation regarding vaginal packing after laparoscopic sacrocolpopexy exists.
- Trial name
- NCT02943525
- Testing
- vaginal packing
- Where
- Czechia
- Volunteers
- 253 people
- Sponsor
- Charles University, Czech Republic
Neurological Diseases or Conditions, Stroke, Acute
COVID-19 Prevalence and Cognitive Deficits in Neurological Patients
The purpose is to investigate the COVID-19 prevalence, associated morbidity and long-term cognitive deficits in consecutive patients presenting with acute neurological symptoms
- Conditions
- Neurological Diseases or Conditions, Stroke, Acute, Seizure Disorder
- Trial name
- Neuro-Covid (NCT04377425)
- Testing
- COVID-19 swap test PCR
- Where
- 4 sites in Denmark
- Sponsor
- Aarhus University Hospital
Critical Illness, Sedation Complication
Sedation, ANalgesia and Delirium MANagement in Intensive Care Unit
Patients with acute severe health problems often need to be admitted to specialised hospital wards called Intensive Care Units (ICUs) where they can receive emergency treatment such as mechanical ventilation to support their…
- Conditions
- Critical Illness, Sedation Complication, Intensive Care Unit Delirium, Analgesia
- Trial name
- SAnDMAN (NCT05027217)
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 3,421 people
- Sponsor
- University of Oxford
Pain, Chronic
Mobile-Based Contingency Management to Promote Daily Self-monitoring in Primary Care Patients
This project examines the efficacy and feasibility of contingency management (CM), delivered using a novel, fully automated CM app (DynamiCare Rewards), to promote daily self-monitoring of pain symptom severity and related…
- Trial name
- ProMPT (NCT03962491)
- Testing
- Daily Self-Monitoring Surveys + Contingency Management, Daily Self-Monitoring Surveys
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Virginia Commonwealth University
Analgesia
Analgesic Protocol With Gabapentin Dexmedetomidine For Postoperative Pain Managment
Assessment of quality of post mastectomy analgesic protocol of Gabapentin and Dexmedetomedine in a placebo-controlled study
- Trial name
- NCT04976374
- Testing
- Dexmedetomidine and Gabapentin, Saline
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- National Cancer Institute, Egypt
Low Back Pain, Facet Joint Pain
Ultrasound-Guided Thermocoagulation of Medial Nerve Branch in Lumbar Facet Joints Pain.
We propose here to evaluate the precision of lumbar thermocoagulation performed under a transverse ultrasound approach by performing a fluoroscopic control once the needle in the desired position.
- Conditions
- Low Back Pain, Facet Joint Pain, Facet Syndrome of Lumbar Spine, Chronic Low Back Pain
- Trial name
- NCT03564418
- Testing
- Ultrasound-Guided Thermocoagulation of Lumbar facet joints, Fluoroscopy-Guided Thermocoagulation of Lumbar facet joints
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- Erasme University Hospital
Peripheral Arterial Occlusive Disease
Interest of a Bi-truncal Nerve Block (Femoral + Sciatic) Extended, Systematically Associated With General Anesthesia, in the Femoropopliteal Bypass: Study of Post-operative Analgesia and Peripheral Circulation Downstream
The aim of this study is to assess, in patients scheduled for femoropopliteal bypass, the benefit of a double peripheral nerve block (femoral + sciatic) with levobupivacaine and clonidine in a single dose, performed before…
- Trial name
- BLOC-FEMPOP (NCT01785693)
- Testing
- levobupivacaine, clonidine
- Where
- France
- Volunteers
- 47 people
- Sponsor
- University Hospital, Clermont-Ferrand
Low Back Pain, Sleep Disruption
Effects of Mattress Firmness on Pain in Patients With Chronic Low-Back Pain
The primary study objective is to determine whether mattress firmness affects pain in patients with chronic low-back pain. We hypothesize that mattresses that differ in their firmness and support should have a varying effect on…
- Trial name
- NCT01044121
- Testing
- Mattress Firmness
- Volunteers
- 40 people
- Sponsor
- Sleep To Live Institute
Surgical Wound, Post Operative Pain
Effect of Preemptive Etoricoxib and Dexamethasone on Wound Healing and Clinical Parameters After Third Molar Surgery
The goal of this clinical trial is to compare preemptive single-dose selective cyclooxygenase 2 (COX-2) inhibitor - etoricoxib and dexamethasone use in systemically healthy patients during the surgical extraction of impacted…
- Trial name
- NCT05791721
- Testing
- Etoricoxib 90 Mg Oral Tablet, Dexamethasone 4mg
- Where
- Serbia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Belgrade
Aortic Aneurysm, Thoracoabdominal
Paraplegia Prevention in Aortic Aneurysm Repair by Thoracoabdominal Staging
Aortic aneurysms represent the most common and dangerous aortic diseases. Although conventional aortic repair techniques cure the disease, there is a high risk of paraplegia particularly in extensive thoracoabdominal aneurysms…
- Trial name
- PAPAartis (NCT03434314)
- Testing
- Minimally-Invasive Segmental Artery Coil-Embolization
- Where
- 29 sites in Austria, France and 7 more
- Volunteers
- 500 people
- Sponsor
- University of Leipzig
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