Clinical trials: Neurologic Gait Disorder
Neuromuscular Disorders, Neurodevelopmental Disorders
Efficacy and Usability of the EXPLORER Exoskeleton in Children With Neurodevelopmental Disorders in Natural Environments
Neurodevelopmental disorders often lead to abnormal development of the Central Nervous System (CNS), frequently causing motor dysfunctions such as an inability to stand and walk.
- Trial name
- NCT06765070
- Testing
- EXPLORER
- Where
- 6 sites in Spain
- Volunteers
- 15 people
- Sponsor
- MarsiBionics
Parkinson Disease
Comparison of Different Non-invasive Electrical Stimulation Protocols to Facilitate Rehabilitation in Parkinson's Disease Subjects With Postural Instability and Gait Disorders
The trial will include 51 adult participants with Parkinson's disease and postural instability and gait disorders (PD-PIGD) and 20 age- and sex-matched healthy controls.
- Trial name
- NCT06868160
- Testing
- Rehabilitation, tDCS, tsDCS (first cycle)
- Where
- Italy
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Psychometrics of Two Translated Measurement Tools
Evaluation of Gait Performance in Children With Neuromuscular Diagnoses
The aims of this project are to evaluate the psychometric properties of the German versions of the two performance questionnaires 'Functional Mobility Scale' (FMS) and 'Gillette Functional Assessment Questionnaire - walking…
- Trial name
- NCT02237222
- Testing
- Gait rehabilitation
- Where
- Switzerland
- Volunteers
- 72 people
- Sponsor
- University Children's Hospital, Zurich
Parkinson Disease
Mental Practice Combined With Physical Practice to Improve the Gait Performance of People With Parkinson's Disease
Among the impairments associated to Parkinson's disease, gait disturbance is one of which that has the most negative impact on the independence in daily living activities and quality of life of people living with Parkinson's…
- Trial name
- NCT02904837
- Testing
- Experimental training, Control training
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- University of Sao Paulo General Hospital
Parkinson's Disease
Exercise, Brain Imaging, Cognition, and Gait in Parkinsonism
There is emerging research detailing the relationship between balance/gait/falls and cognition. Imaging studies also suggest a link between structural and functional changes in the frontal lobe (a region commonly associated with…
- Trial name
- EEforPD (NCT02231073)
- Testing
- Exercise and Education for Parkinson's Disease
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Stroke
Tracking Neural Synergies After Stroke.
The purpose of this study is to identify neural muscle synergies of patients post-stroke and track them during an inpatient acute rehabilitation.
- Trial name
- NCT04805866
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Parkinson Disease
Sensor-supported Classification of Gait Patterns in Everyday Movement of Patients With Parkinson's Disease
Within this study we conduct long-term measurements on Parkinson patients using a three sensor IMU setup: one sensor is located at the wrist, one sensor at the belt/ in the pocket and one sensor is worn as a pendant.
- Trial name
- PD-GPC (NCT04054856)
- Testing
- Body Sensor Network
- Where
- Germany
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- RWTH Aachen University
Multiple Sclerosis
Lokomat Training Effects on MS Gait Abnormalities
Multiple sclerosis is a degenerative disease that affects more than 400,000 people in the US alone. MS is in fact the most common disabling neurological disorder in young adults.
- Trial name
- NCT00766272
- Testing
- Lokomat
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- US Department of Veterans Affairs
Neurofibromatosis Type 1
Gait in Young Children With NF1
The objective of this study is to develop office-based tools to quantify gait in young children with NF1 that reflect overall gross motor impairment and predict future gross motor difficulties.
- Trial name
- NCT07564622
- Volunteers
- 56 people
- Sponsor
- NYU Langone Health
Parkinson Disease
Programmes de Marche Active et qualité de Vie Dans la Maladie de Parkinson
The aim of this randomized controlled pilot trial is to assess the impact of different gait rehabilitation programs on the level of physical activity and gait in daily life in patients with Parkinson's disease (PD).
- Trial name
- ACTI-PARK (NCT05685095)
- Testing
- Physical training
- Where
- France
- Sponsor
- University Hospital, Grenoble
Stroke
Post-stroke Recovery (PSR_e2020)
The study presented is part of the departmental project entitled: BEHAVIORS AND WELLNESS: A MULTIDISCIPLINARY APPROACH TO PROMOTE THE QUALITY OF LIFE IN VULNERABILITY CONDITIONS - winner of the MIUR grant "Departments of…
- Trial name
- PSR_e2020 (NCT04323501)
- Testing
- Experimental treatment, Control group
- Where
- Italy
- Volunteers
- 134 people
- Sponsor
- Universita di Verona
Cerebral Palsy, Spina Bifida
The Effects of a Powered Knee Orthosis on Gait Kinematics of Children With Knee Extension Deficiency
Crouch gait/walking, characterized by an 'over-flexed' knee when the leg is supporting body weight, is common in children with diagnoses of cerebral palsy, spina bifida and other incomplete spinal cord injuries.
- Conditions
- Cerebral Palsy, Spina Bifida, Spinal Cord Injuries
- Trial name
- NCT05330052
- Testing
- Agilik
- Where
- Canada
- Volunteers
- 4 people
- Sponsor
- University of British Columbia
Parkinson Disease, Gait Disorders, Neurologic
Spinal Cord Stimulation for Gait Disorders in Parkinson's Disease
Our project is based on the fundamental hypothesis that epidural spinal cord stimulation (SCS) improves Freezing of gait (FOG) in patients with Parkinson's disease.
- Trial name
- SCM-PARK (NCT04682678)
- Testing
- Implantation of electrodes for Spinal cord stimulation
- Where
- France
- Volunteers
- 6 people
- Sponsor
- University Hospital, Grenoble
Multiple Sclerosis, Gait Disorders, Neurologic
Walking and Thinking - Brain Activity During Complex Walking in People With Multiple Sclerosis
Every-day life means being part of a complex environment and performing complex tasks that usually involve a combination of motor and cognitive skills.
- Conditions
- Multiple Sclerosis, Gait Disorders, Neurologic, Neuro-Degenerative Disease, Aging
- Trial name
- NCT05787704
- Testing
- No intervention
- Where
- Sweden
- Volunteers
- 41 people
- Sponsor
- Karolinska Institutet
Parkinson Disease
Gait Training With antiGRAVIty TREadmill 'Alter-G', in Patients With ParkinSON Disease
Parkinson's disease (PD) is a neurodegenerative disease characterized mainly by motor symptoms, in particular rigidity, akinesia, tremor, which are associated with postural reflex deficits, impaired balance and gait deficit, with…
- Trial name
- NCT05784025
- Testing
- AlterG
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
NPH (Normal Pressure Hydrocephalus)
The Effects of Exercise on Gait Characteristics, Balance, and Performance in Patients With Normal Pressure Hydrocephalus
The goal of this study is to investigate effect of exercise program on balance, gait and performance in patients with normal pressure hydrocephalus applied with lumbar puncture.
- Trial name
- NCT05679934
- Testing
- Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 41 people
- Sponsor
- Dokuz Eylul University
Parkinson Disease
Cueing-assisted Gamified Augmented-reality Gait-and-balance Rehabilitation at Home for People With Parkinson's Disease
Background: Physiotherapy in the clinic is highly recommended for improving gait, balance and falls risk in people with Parkinson's disease. In addition, technology may help boost unsupervised exercise hours at home.
- Trial name
- CAPARE (NCT06590987)
- Testing
- Strolll AR
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- VU University of Amsterdam
PARKINSON DISEASE (Disorder), Parkinson Disease (PD)
Cognitive-Based Balance Rehabilitation in Parkinson's Disease: Virtual Reality vs. Dual Task
This prospective, randomized, single-blind, controlled clinical trial aims to evaluate and compare the efficacy of cognitive-based balance rehabilitation delivered via immersive Virtual Reality (VR) versus traditional Dual-Task…
- Conditions
- PARKINSON DISEASE (Disorder), Parkinson Disease (PD), Parkinson s Disease, Postural Instability
- Trial name
- NCT07660978
- Testing
- Dual Task Training (DTT), Virtual Reality Training (VRT)
- Volunteers
- 34 people
- Sponsor
- Bezmialem Vakif University
Freezing of Gait, Parkinson's Disease
Etiology-Phenotype-Outcome Pathway Study on Freezing of Gait (FOG)
This study is a prospective, multicenter, observational cohort (patient registry) designed to better understand freezing of gait (FOG), a disabling walking problem that can occur in Parkinson's disease and other related…
- Conditions
- Freezing of Gait, Parkinson's Disease, Parkinsonism, Vascular Parkinsonism
- Trial name
- NCT07386015
- Testing
- Observational Data Collection
- Where
- China
- Volunteers
- 700 people
- Sponsor
- Tianjin Huanhu Hospital
Pregnancy Related, Epidural; Anesthesia, Headache
Inertial Sensors for Obstetrical Walking Epidural Tracking
Freedom of movement and the ability to walk are crucial during the first stage of labor, potentially reducing labor duration, cesarean section risk, epidural analgesia use, and bladder catheterization.
- Conditions
- Pregnancy Related, Epidural; Anesthesia, Headache, Labor Complication
- Trial name
- MOTION-EASE (NCT06471790)
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Hospices Civils de Lyon