Clinical trials: Neurologic Gait Disorder
Chronic Obstructive Pulmonary Disease, Balance Impairment
The Relationship Between Pain, Balance and Gait in People With Chronic Obstructive Pulmonary Disease
The balance, gait and pain in Chronic Obstructive Pulmonary Disease (COPD) study will aim to investigate the link between balance and gait impairment, and high rates of pain in people with COPD.
- Conditions
- Chronic Obstructive Pulmonary Disease, Balance Impairment, Gait Impairment, Pain
- Trial name
- NCT04202991
- Testing
- Exposure - pain
- Where
- 2 sites in United Kingdom
- Volunteers
- 43 people
- Sponsor
- Teesside University
Spinal Cord Injury
Exercise Testing During Treadmill Gait in Incomplete Spinal Cord Injury
Treadmill therapy has the potential to improve the physical fitness and voluntary function of incomplete-lesion spinal cord injured (SCI) patients.
- Trial name
- NCT00204126
- Testing
- Treadmill with partial body weight support, Surface Functional Electrical Stimulation
- Where
- 2 sites in United Kingdom
- Volunteers
- 4 people
- Sponsor
- University of Glasgow
Parkinson Disease
Study on Preliminary Safety and Efficacy of Adaptive DBS Aligned to Locomotor States to Improve Locomotor Functions in Parkinson's Patients
At present, there is no cure for Parkinson's disease. The standard treatment involves taking dopaminergic drugs. When drugs lose their effectiveness, they can be supplemented by Deep Brain Stimulation (DBS) therapy.
- Trial name
- AdapGAIT (NCT06791902)
- Testing
- Adaptive DBS
- Where
- Switzerland
- Volunteers
- 10 people
- Sponsor
- Jocelyne Bloch
Stroke, Stroke, Acute
Achieving Meaningful Clinical Benchmarks With Ekso Gait Training During Acute Stroke Inpatient Rehabilitation.
The Ekso (Ekso Bionics) is a wearable exoskeleton that provides robotic support and walking assistance for patients with lower extremity paralysis.
- Conditions
- Stroke, Stroke, Acute, Cerebrovascular Accident, Cerebrovascular Accident, Acute
- Trial name
- NCT05241457
- Testing
- Ekso gait training, Standard physical therapy
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Sunnyview Rehabilitation Hospital
Stroke, Aging
Walking and Thinking - Brain Activity During Complex Walking in Stroke
Everyday life requires individuals to function in complex environments and perform tasks that involve the integration of motor and cognitive abilities.
- Conditions
- Stroke, Aging, Neuro-Degenerative Disease, Gait Impairment in Stroke Patients
- Trial name
- NCT07624630
- Testing
- No Interventions
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Karolinska Institutet
Cerebral Palsy
Telehealth-Supervised Resistance Training for Children With Cerebral Palsy
The goal of this clinical trial is to evaluate the feasibility and potential benefits of telehealth-supervised resistance training in ambulatory children aged 6 to 15 years with cerebral palsy (CP) classified as Gross Motor…
- Trial name
- NCT07061275
- Testing
- Telehealth-Supervised Resistance Training
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Hunan Normal University
Parkinson Disease
Effects of Different Percentages Body Weight Supported Treadmill Training on Gait, Balance, Quality of Life and Fatigue in Parkinson's Disease
Body weight supported treadmill training (BWSTT) is an important rehabilitative choice for neurologically impaired subjects such as Parkinson's disease (PD).
- Trial name
- NCT03799887
- Testing
- 0% unweighed BWSTT, 10% unweighed BWSTT, 20% unweighed BWSTT
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Hitit University
Stroke
Effectiveness of an Exoskeleton Gait Training Versus Manual Therapy in Subacute Post Stroke Patients.
The main objective of the present study was to compare the effects of exoskeleton devices used in electromechanical-assisted gait training after stroke compared to over ground conventional physical therapy in a single blind…
- Trial name
- NCT02095795
- Testing
- Technological Rehabilitation, Control Rehabilitation
- Where
- 2 sites in Italy
- Volunteers
- 28 people
- Sponsor
- Giovanni Taveggia
Cerebral Palsy
Exoskeleton-assisted Physiotherapy for Children With Mobility Impairments
Non-ambulatory children with cerebral palsy (CP) and similar childhood-onset neuromotor conditions face many challenges to fulsome participation in everyday life.
- Trial name
- NCT05463211
- Testing
- Trexo Plus Pediatric Exoskeleton
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Spinal Cord Injury
Effects of Lokomat Training on Dynamic Postural Stability in Incomplete Spinal Cord Injury
The study aims to evaluate the effects of robotic-assisted gait training (Lokomat) on dynamic postural stability in patients with incomplete spinal cord injury (SCI).
- Trial name
- NCT07621900
- Testing
- Robotic Rehabilitation, Control
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Concussion, Eye
The Effects of Concussion on Gait and Posture in Individuals With Peripheral Vision Loss
Changes in gait and balance often occur in individuals who have suffered a concussion. In addition, a subset of concussed individuals also experience peripheral vision loss.
- Trial name
- NCT05948501
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Gaylord Hospital, Inc
Parkinson's Disease With Freezing of Gait
Neurophysiological Dissection and Intervention of Freezing of Gait in Parkinson's Disease
Different conditions of gait ignition freezing, spontaneous freezing during walking and turning freezing on encountering obstacle will be investigated in fMRI study to examine whether different regions of brain will be involved…
- Trial name
- NCT03127475
- Testing
- Transcranial direct current stimulation
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- China Medical University Hospital
CP (Cerebral Palsy), Robotic Exoskeleton
Study Aims to Compare the Effect of Robotic-assisted Gait Training and Conventional Treadmill Training on Postural Stability in Ambulatory Children With Cerebral Palsy.
The aim of this study is to explore the impact of gait training with a robotic device versus treadmill training on enhancing postural stability and walking capabilities in children with cerebral palsy (CP).
- Conditions
- CP (Cerebral Palsy), Robotic Exoskeleton, Treadmill Locomotor-based Training, Postural Stability
- Trial name
- NCT06719271
- Testing
- Participants this group will receive gait training in robotic assisted gait training (RAGT) three times per week for eight weeks, Body Weight Supported Treadmill Training
- Where
- Saudi Arabia
- Volunteers
- 36 people
- Sponsor
- King Saud University
Cerebral Palsy
Safety and Performance of Agilik in CP
The purpose of this post market study is to demonstrate the safety and performance of a powered extension assist (EA) knee ankle foot orthosis (KAFO), or EA-KAFO, in individuals with knee extension deficiency due to cerebral…
- Trial name
- Agilik (NCT05746871)
- Testing
- Agilik, standard care
- Where
- Italy
- Volunteers
- 9 people
- Sponsor
- IRCCS Eugenio Medea
Cerebral Palsy
Effects of Robotic Gait, Hydrotherapy, and Conventional Physiotherapy in Spastic Hemiparetic CP
This study aims to evaluate the effects of three different physiotherapy approaches-robot-assisted gait training, hydrotherapy, and conventional physiotherapy-on muscle strength, balance, functional mobility, and psychological…
- Trial name
- NCT07031609
- Testing
- Robot-assisted gait training using Lokomat, Hydrotherapy, Conventional Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Istanbul Arel University
Parkinson Disease
Targeted Motor Learning to Improve Gait for Individuals With Parkinson Disease
The purpose of this research study is to determine how training to step with a metronome on both a treadmill, as well as overground, will influence the way that people with Parkinson disease walk.
- Trial name
- NCT05864157
- Testing
- Gait training without rhythmic auditory cues, TRAC, dTRAC
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of North Carolina, Chapel Hill
Parkinson Disease, Walking, Difficulty
Model-based Cueing-as-needed for Walking in Parkinson's Disease
Correcting of the lack of regularity in steps is a key component of gait rehabilitation in Parkinson's disease. The proposal is to introduce adaptive spatial auditory cueing (ASAC) based on verbal instruction "lengthen the step"…
- Conditions
- Parkinson Disease, Walking, Difficulty, Gait, Festinating
- Trial name
- GAITPARK (NCT06073028)
- Testing
- 20-minute gait training
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Henri Mondor University Hospital
Stroke
Post Stroke Walking Kinematics Using the Honda Walking Assist Robotic Exoskeleton
To investigate the effect of a robotic exoskeleton on kinematics, muscle activity, ground reaction forces and spatiotemporal characteristics during walking in persons post stroke.
- Trial name
- NCT03828214
- Testing
- Robotic exoskeleton for walking assist
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- College of St. Scholastica, Inc.
Spinal Cord Injury
Safety Study of Outdoor and Indoor Mobility in People With Spinal Cord Injury (ROBOtics Spinal Cord Injury EKSO).
The aim of this study will be to evaluate the safety and the efficacy of a new robotic exoskeleton device in subjects with Spinal Cord Injury (SCI) and in subjects with other neurological disease with an impairment of lower limbs.
- Trial name
- ROBOSCIEKSO (NCT02065830)
- Testing
- EKSO
- Where
- 2 sites in Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele Roma
Stroke
Error Based Learning for Restoring Gait Symmetry Post-Stroke
Many of the 780,000 people affected by stroke each year are left with slow, asymmetric walking patterns. The proposed project will evaluate the effectiveness of two competing motor learning approaches to restore symmetric gait…
- Trial name
- NCT01598675
- Testing
- Same Belt Speeds, Different Belt Speeds
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of North Carolina, Chapel Hill
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