Clinical trials: Neurologic Gait Disorder
Subluxation
Simulated vs Genuine Manual Chiropractic Adjustments
Our primary aim with this trial is to measure participant blinding following two simulated/sham or genuine/real high velocity, low amplitude (HVLA) manual chiropractic adjustments to assess if participants are able to identify…
- Trial name
- SHA (NCT06931600)
- Testing
- Chiropractic adjustment
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Life University
Multiple Sclerosis
The Therapeutic Effects of Forced Aerobic Exercise in Multiple Sclerosis
This project will investigate the feasibility and initial efficacy of two aerobic exercise training approaches, forced and voluntary, to improve motor function in persons with multiple sclerosis (MS).
- Trial name
- NCT04906057
- Testing
- Forced Aerobic Exercise (FE), Voluntary Aerobic Exercise (VE)
- Where
- 2 sites in United States
- Volunteers
- 22 people
- Sponsor
- The Cleveland Clinic
Stroke
Replacing Canes With an Elasticated Orthosis in Chronic Stroke Patients: The Influence on Gait and Balance. A Series of N-of-1 Trials
This study aims to investigate the effect of an elasticated orthotic garment "Thera Togs" on walking ability and balance in currently cane using chronic stroke subjects (minimum 6 months post stroke) using a series of N-of-1…
- Trial name
- NCT03642444
- Testing
- Cane, Elasticated worn orthotic-garment
- Volunteers
- 4 people
- Sponsor
- Technical University of Bern
Post-stroke, Hemiplegic Gait
Evaluation of the Mechanisms of Weight-bearing of the Hemiplegic Limb During Table Tennis Sessions in the Framework of Post-stroke Rehabilitation : Pilot Study
This is an experimental, observational, prospective study designed to develop medical knowledge. The primary objective of the study is to analyze the weight bearing of the hemiplegic side according to the different areas of…
- Conditions
- Post-stroke, Hemiplegic Gait, Rehabilitation
- Trial name
- HEMITENNIS (NCT05857072)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- FondationbHopale
Parkinson Disease, Idiopathic
Integration of Augmented Visual Feedback in Action Observation and Motor Imagery Therapy for Parkinson's Disease
Improving movement control during rehabilitation is still a challenge for people with Parkinson's Disease, mainly because of the motor symptoms caused by the condition.
- Trial name
- NCT07094828
- Testing
- AOMI with D-Wall, Routine physiotherapy with D-Wall
- Volunteers
- 86 people
- Sponsor
- University of Bergamo
Multiple System Atrophy, Autonomic Failure
Deep Brain Stimulation for Autonomic and Gait Symptoms in Multiple System Atrophy
Patients referred to neurosurgery routinely and safely undergo deep brain stimulation (DBS) for treatment of symptoms related to neurodegenerative conditions, most commonly Parkinson's disease.
- Conditions
- Multiple System Atrophy, Autonomic Failure, Postural Hypotension, Bladder, Neurogenic
- Trial name
- STAG-MSA (NCT03593512)
- Testing
- Deep brain stimulation
- Where
- United Kingdom
- Volunteers
- 5 people
- Sponsor
- University of Oxford
Cardiovascular Diseases, Stroke Sequelae
Gait Training for Concurrent Optimization of Weight Mgt,bp Regulation and Functional Mobility
Stroke is a leading cause of long-term disability and death worldwide, with chronic survivors often experiencing gait disturbances (affecting up to 80%), reduced physical activity, and cardiometabolic comorbidities like obesity…
- Trial name
- NCT07420595
- Testing
- Weeks 1-6: EAGT (exoskeleton/end-effector devices; 30- 50% body-weight support, speed 1.5-2 km/h, ≥800-1200 steps/session). Weeks 7-12: CGT (overground walking, obstacles, stairs, dual-tasks)., Full 12 weeks CGT, progressing complexity and demands.
- Where
- Pakistan
- Volunteers
- 140 people
- Sponsor
- Iqra National University
Gait Apraxia, Alzheimer Disease
Gait and Alzheimer Interaction Tracking (GAIT) Study
The purpose of this study is to examine and to compare gait characteristics under single- and dual-task conditions among healthy subjects together with AD patients at different stages of disease (i.e., pre-dementia, mild and…
- Conditions
- Gait Apraxia, Alzheimer Disease, Impaired Cognition, Cerebral Atrophy
- Trial name
- GAIT (NCT01315717)
- Where
- France
- Volunteers
- 912 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Cerebral Palsy
Treadmill Training at Variable Inclinations in Children With Cerebral Palsy
This study aimed to evaluate the effect of treadmill training (TT) at different inclinations on balance, strength, flexibility, and gait parameters in children with cerebral palsy (CP) in addition to traditional physiotherapy…
- Trial name
- NCT06216652
- Testing
- downhill walking, uphill walking, walking with no incline
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Pamukkale University
Idiopathic Parkinson's Disease (PD)
Association of VAgus Nerve Stimulation and Treadmill Training for GAit Rehabilitation in DE Novo Parkinson's Disease
The goal of this clinical trial is to learn if transcutaneous auricular vagus nerve stimulation (taVNS) can improve gait and brain function in people with diagnosis of idiopathic Parkinson's disease (PD) within 6 months.
- Trial name
- AVANTGARDE-PD (NCT07337226)
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation (taVNS), Conventional Physical Therapy (cPT), Sensorized Treadmill Training (STT)
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Fondazione Policlinico Universitario Campus Bio-Medico
Stroke
Exergames on an Unstable Surface in Stroke Inpatients
Aim of this study is to assess the feasibility and effects of exergame-based cognitive-motor training on a labile platform on physical and cognitive functioning in stroke inpatients.
- Trial name
- NCT06296069
- Testing
- exergame-based cognitive-motor training on an unstable surface, exergame-based cognitive-motor training on an stable surface
- Where
- Switzerland
- Volunteers
- 29 people
- Sponsor
- Eleftheria Giannouli
Cerebral Palsy
Botulinum Toxin Efficiency on Spasticity of Rectus Femoris and Semitendinosus Muscles as Functional Agonist and Antagonist Muscles
The aim of the study is to confirm the functional improvement obtained through treatment of spasticity on 2 agonist and antagonist muscles.
- Trial name
- NCT00133861
- Testing
- Botulinum toxin
- Where
- France
- Volunteers
- 23 people
- Sponsor
- Hospices Civils de Lyon
Sub-acute Stroke
Home and Clinic Rehabilitation in Subacute Stroke
The goal of this clinical trial is to learn if adding scheduled home-based rehabilitation to clinic-based rehabilitation improves walking ability and daily activities in people aged 40 to 50 with sub-acute stroke.
- Trial name
- ADLS PAC HBP (NCT07613554)
- Testing
- Physical Therapy Rehabilitation Program
- Volunteers
- 72 people
- Sponsor
- University of Lahore
Diabetic Polyneuropathy
Differential Air Pressure Technology for Treatment of Diabetic Elderly Patients
Aging can be defined as sequential deterioration that occurs in elderly people including weakness, loss of mobility, decline of physical capabilities, increase susceptibility to disease and many other age-related physiological…
- Trial name
- NCT04620265
- Testing
- Antigravity treadmill training 100% weight bearing, Antigravity treadmill training 75% weight bearing, Antigravity treadmill training 50% weight bearing
- Where
- Saudi Arabia
- Volunteers
- 110 people
- Sponsor
- Umm Al-Qura University
Parkinson Disease
Effects of Directional Subthalamic Deep Brain Stimulation on Gait and Balance in Parkinson's Disease Patients
Deep brain stimulation of the NST is effective for cardinal motor signs in patients with idiopathic Parkinson's disease (IPD), its effects on gait disturbances, especially freezing of gait-FOG, and falls are variable from one…
- Trial name
- MAGIC (NCT04223427)
- Testing
- Directional and single ring STN-DBS on gait
- Where
- France
- Volunteers
- 19 people
- Sponsor
- University Hospital, Rouen
Parkinson's Disease
Comfort and Tolerance of Surface Neuro Muscular Electrical Stimulation in Parkinson's Disease.
The purpose of this study is to investigate issues relating to comfort and tolerance to surface neuro muscular electrical stimulation in a parkinson disease population.
- Trial name
- NCT01968473
- Testing
- NMES Device comfort
- Where
- Ireland
- Volunteers
- 10 people
- Sponsor
- National University of Ireland, Galway, Ireland
Parkinson Disease (PD)
Transcranial Magnetic Stimulation for Freezing of Gait in Parkinson's Disease
This study evaluated transcranial magnetic stimulation (TMS) for freezing of gait in patients with Parkinson's disease. Participants with Parkinson's disease and freezing of gait received conventional TMS protocols, and their…
- Trial name
- PD-FOG-TMS (NCT07731841)
- Testing
- Primary Motor Cortex Transcranial Magnetic Stimulation, Spinal Cord Magnetic Stimulation, SMA TMS
- Where
- China
- Volunteers
- 85 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Hypoxic-Ischemic Encephalopathy, Periventricular Leukomalacia
Evaluation of Long-Term Gait Development in Infants With Neonatal Encephalopathy Using Infant Treadmill
There have been many studies on the use of running training in older children to improve gait development in children with cerebral palsy.
- Conditions
- Hypoxic-Ischemic Encephalopathy, Periventricular Leukomalacia, Intraventricular Hemorrhage Neonatal, Bilirubin Encephalopathy
- Trial name
- NCT03534466
- Testing
- Baby treadmill, Conventional physical rehabilitation training
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Children's Hospital of Fudan University
Alzheimer's Dementia, Falls
Wii-Fit For Improving Activity, Gait And Balance In Alzheimer's Dementia
Alzheimer's Dementia (AD) contributes to poor balance, impaired gait and functional status, thereby, increasing the risk of falls. AD is an independent risk factor for hip fractures.
- Conditions
- Alzheimer's Dementia, Falls, Gait Impairment, Balance Impairment
- Trial name
- NCT01002586
- Testing
- Wii-Fit intervention, Walking exercise program
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Nebraska
Stroke, Dementia
Taiwan Post-Stroke Disability Study
Stroke remains a major health issue in Taiwan, being the fourth leading cause of death and the top cause of disability. While past research has focused on functional outcomes at three months post-stroke, stroke can cause a range…
- Conditions
- Stroke, Dementia, Epilepsy, Depression
- Trial name
- T-PODS (NCT06772194)
- Where
- Taiwan
- Volunteers
- 2,000 people
- Sponsor
- National Taiwan University Hospital
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