Clinical trials: Neurologic Gait Disorder
Spastic Cerebral Palsy (sCP)
Stop Tip-toeing Around Toe-walking
The purpose of this study is to explore the interplay among nervous-, musculoskeletal-, and psychological systems and how they impact toe-walking behavior, and vice versa.
- Trial name
- NCT04879199
- Testing
- Static stability measurement, Dynamic stability measurement
- Where
- Switzerland
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University Children's Hospital Basel
Spinal Cord Injuries, Multiple Sclerosis
Deficit-specific Training in Spinal Disorders
Impairments of walking function after spinal cord lesion due to, for example, inflammation, ischemia or trauma are exceptionally diverse.
- Conditions
- Spinal Cord Injuries, Multiple Sclerosis, Gait Disorders, Neurologic, Training
- Trial name
- NCT04292717
- Testing
- Gait training
- Where
- Switzerland
- Volunteers
- 63 people
- Sponsor
- University of Zurich
Stroke
Effects of Jaw Clenching on Gait and Mobility in Stroke
The aim of this study is to investigate the immediate effects of jaw clenching on gait and functional mobility in patients with chronic stroke.
- Trial name
- NCT07612397
- Testing
- Voluntary Jaw Clenching
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Bitlis Eren University
Stroke
Gait Training For Acute Stroke: Functional Neuromuscular Stimulation (FNS) and Weight Supported Treadmill Training
Conventional rehabilitation does not restore normal, safe gait to many stroke survivors. Functional neuromuscular stimulation (FNS) using intramuscular (IM) electrodes (FNS-IM) improved persistent gait deficits for patients with…
- Trial name
- NCT00101543
- Testing
- Electrical Stimulation with Intramuscular Electrodes, Body Weight Supported Treadmill Training
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- US Department of Veterans Affairs
Parkinson Disease, Freezing of Gait
Motor Adaptation to Split-Belt Treadmill in Parkinson's Disease
Freezing of Gait (FOG) is a disabling symptom common in advanced Parkinson's Disease. FOG is an independent contributor to fall risk and is only partially relieved by medication.
- Trial name
- NCT03725215
- Testing
- Split-Belt Treadmill Training
- Where
- 2 sites in Belgium, Germany
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Stroke
Effect of a Physiotherapy Protocol for Gait and Functional Recovery After Stroke
The purpose of this study was to identify and evaluate the effect of a new protocol of physiotherapy to retrain walking ability after stroke in subjects older than fifty-five.
- Trial name
- NCT02250040
- Testing
- Conventional physiotherapy, Techniques based on patients' functional level were added.
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- University of Valencia
Neuromuscular Disorders
Safety and Usability of the EXPLORER Exoskeleton in Adults With Neuromuscular Diseases
Neurodevelopmental disorders frequently result in abnormal development of the Central Nervous System (CNS), often leading to motor impairments such as difficulty in standing and walking.
- Trial name
- NCT06894160
- Testing
- Adults EXPLORER
- Where
- Spain
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- MarsiBionics
Parkinson Disease
The Influence of Manual and Verbal Guidance for Therapeutic Results in People With Parkinson's Disease
A prospective, single-blind, parallel-group, randomised trial was conducted in Sao Paulo, Brazil. Thrid eight People with Parkinson's Disease were recruited and randomly allocated in two groups: Experimental Group (EG), that…
- Trial name
- NCT03774225
- Testing
- Virtual Reality with Manual and Verbal Guidance, Virtual Reality with No Manual and Verbal Guidance, Physical Therapy
- Where
- 2 sites in Brazil
- Volunteers
- 49 people
- Sponsor
- University of Sao Paulo General Hospital
Parkinson's Disease
Subthalamic Nucleus, Akinesia and Parkinson's Disease
This program aims to understand the role of the subthalamic nucleus in the control of the movement in healthy humans and patients with Parkinson's disease, how the STN dysfunction contributes to akinesia and how the STN…
- Trial name
- GB-MOV (NCT01682668)
- Testing
- Bilateral subthalamic stimulation
- Where
- 2 sites in France
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Stroke
Implementation of Comprehensive Stroke Rehabilitation Therapy for Enhanced Quality of Life
The purpose of this research study is to implement into clinical practice, the comprehensive QualPro protocol for stroke survivors, which includes gait coordination, balance, mobility, and fitness training.
- Trial name
- QualPro (NCT02225990)
- Testing
- Experimental Group, Sub-Acute, Experimental Group, Chronic, Standard of Care, Sub-Acute
- Where
- 3 sites in United States
- Volunteers
- 9 people
- Sponsor
- University of Florida
Stroke, Gait Disorders, Neurologic
ZEPU AI9 Exoskeleton Rehabilitation Robot
The goal of this clinical trial is to learn whether the ZEPU AI9 lower limb exoskeleton robot is feasible, safe, and effective for people with walking difficulty caused by stroke, incomplete spinal cord injury, or orthopedic…
- Conditions
- Stroke, Gait Disorders, Neurologic, Spinal Cord Injuries, Incomplete, Postoperative Complication
- Trial name
- NCT07750808
- Testing
- ZEPU-AI9 Lower Limb Exoskeleton Gait Training, Standard-of-Care Rehabilitation
- Where
- Bangladesh
- Volunteers
- 36 people
- Sponsor
- Bangladesh Medical University
Parkinson Disease
Combined Deep Brain Stimulation for Parkinson's Disease
Background: Deep brain stimulation (DBS) in the subthalamic nucleus (STN) is an approved treatment for Parkinson s disease. It stimulates a part of the brain that helps control symptoms like tremor, stiffness, and slow movements.
- Trial name
- NCT01485276
- Testing
- DBS Surgery
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Spinal Cord Injury
Deep Brain Stimulation in Patients With Incomplete Spinal Cord Injury for Improvement of Gait
Spinal cord injuries are anatomically mostly incomplete, showing tissue bridges of the spinal cord at the injury site. Of the 60% functionally incomplete patients, about half face a life in the wheelchair.
- Trial name
- DBS-SCI (NCT03053791)
- Testing
- Deep brain stimulation in mesencephalic locomotor region, Implantation of a Deep brain stimulation system
- Where
- Switzerland
- Volunteers
- 5 people
- Sponsor
- University of Zurich
Cerebral Palsy, Balance
The Relationship of Forward and Backward Walking with SMC, Trunk Control and Balance in Children with Cerebral Palsy
Children aged between 6-18 years old, diagnosed with cerebral palsy and meeting the inclusion criteria, will be included in this study.
- Conditions
- Cerebral Palsy, Balance, Gait Disorders in Children
- Trial name
- NCT05962749
- Testing
- Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Alanya Alaaddin Keykubat University
Idiopathic Normal Pressure Hydrocephalus (INPH)
Change in Cognition and Frailty After Shunt Surgery in Idiopathic Normal Pressure Hydrocephalus (iNPH)
The goal of this observational study is to describe changes in cognitive profile and frailty from pre shunt to one year after the shunt surgery and to identify clinical predictors of an improvement in terms of cognition and…
- Trial name
- NCT07642726
- Testing
- Ventriculoperitoneal shunt
- Where
- Norway
- Volunteers
- 276 people
- Sponsor
- Oslo University Hospital
Stroke
Clinical Applicability of Robot-assisted Gait Training System in Acute Stroke Patients
Investigation of the clinical feasibility and efficacy of a newly developed robot-assisted gait training system for acute stroke survivors.
- Trial name
- NCT02755415
- Testing
- HIWIN Robotic Gait Training System, Static Standing Table
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- China Medical University Hospital
Fibromyalgia, Chronic Pain
Assessment of Posture, Balance, Gait Disorders in Patients With Fibromyalgia
The study aims to determine the posture, balance and gait disorders objectively in patients with fibromyalgia (FM) and to investigate their relationships with disease-related parameters.
- Trial name
- NCT06245226
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
tDCS, Sham tDCS
tdCS Combined With Treadmill Training in Patients With Multiple Sclerosis
This clinical trial aims to evaluate the therapeutic effectiveness of transcranial direct current stimulation (tDCS), a non-invasive technique that modulates cortical excitability, in combination with gait training in patients…
- Trial name
- TDCS (NCT06986278)
- Testing
- tDCS
- Where
- 2 sites in Spain
- Volunteers
- 78 people
- Sponsor
- University of Castilla-La Mancha
Parkinson Disease
Asymmetric Targeted DBS for PD With PIGD
The purpose of this study is to compare the effectiveness of the deep brain stimulation of asymmetric targets [subthalamic nucleus (STN) in the right hemisphere while globus pallidus interna (GPi) in the left] versus the…
- Trial name
- ATS-PIGD (NCT05397340)
- Testing
- Deep brain stimulation
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Ruijin Hospital
Neuropathy Demyelinating
Posturography-Neuropathy
If the classification between hereditary and acquired neuropathy is often easy, there is no completely specific marker allowing the distinction between the two etiologies.
- Trial name
- PONE (NCT04154540)
- Testing
- Motion analysis
- Where
- France
- Volunteers
- 67 people
- Sponsor
- University Hospital, Lille
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