Clinical trials: Neurologic Gait Disorder
Parkinson Disease
Freezing of Gait Correction and Fall Prevention: Developing a Real-time Somatosensory Stimulation System
Background and purpose: Freezing of gait (FOG) is one of the most disabling motor symptoms in people with Parkinson's disease (PD), and closely associates with postural instability and fall.
- Trial name
- NCT01772186
- Testing
- Real-time somatosensory cue
- Where
- 2 sites in Taiwan
- Volunteers
- 50 people
- Sponsor
- National Taiwan University Hospital
Parkinson Disease
Dual Task Training in Parkinson's Disease
The aim of study is to analyze the effects of dual task training on balance, gait, cognition and neurotrophic factors in Parkinson's disease.
- Trial name
- NCT04115683
- Testing
- Dual Task Training, Single Task Training
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Gazi University
Parkinson Disease
Strategy for Daily Activity Improvement in Patients With Parkinson's Disease
The symptoms and signs of patients with Parkinson's disease (PD) include bradykinesia, rigidity, tremor and poor sensory integration, which result in mobility disability.
- Trial name
- Parkinson (NCT03972241)
- Testing
- foot insole
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kwan-Hwa Lin
Charcot Marie Tooth Disease (CMT)
CMT Gait, Mobility, Balance - AOFAS Grant
The overall objective of the proposed research is to begin to better understand the potential benefits and limitations of ankle -foot orthosis (AFO) use in the context of mobility and balance during gait for individuals with…
- Trial name
- NCT07188415
- Testing
- Ankle-foot Orthoses
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Bopha Chrea
Rehabilitation, Parkinson Disease
Golden Walk as Measure of Gait Rehabilitation in Parkinson's Disease
Gait is specifically impaired in Parkinson's disease (PD). External auditory cue based on a binary rhythm tested in PD patients disappear when the stimulus is removed.
- Conditions
- Rehabilitation, Parkinson Disease, Locomotion Disorder, Neurologic, Rhythm; Abnormal
- Trial name
- NCT04706572
- Testing
- Stimulation with external auditory bio-feedback
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Parkinson's Disease
Pedunculopontine Nucleus Stimulation for Gait Disorders in Parkinson's Disease
The appearance of postural instability and gait disorders is a major turning point in the evolution of Parkinson's disease (PD).
- Trial name
- NCT02055261
- Testing
- Low frequency DBS of the pedunculopontine nucleus
- Where
- France
- Volunteers
- 6 people
- Sponsor
- Pitié-Salpêtrière Hospital
Stroke, Gait, Hemiplegic
Assessing the Reliability and Validity of 4-meter and 10-meter Walking Test
The 4-meter walk test and 10-meter walk test is currently applied to assess gait speed.These tools are frequently used in clinical trials and were also shown to be reliable measurement methods.
- Conditions
- Stroke, Gait, Hemiplegic, Cerebral Infarction, Cerebrovascular Disorders
- Trial name
- NCT04919772
- Testing
- Assessment
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Universitat Internacional de Catalunya
Parkinson Disease
Subthalamic Nucleus Stimulation Effect on Gait Symmetry and Freezing of Gait
Impact of unilateral modulation of deep brain stimulation of the subthalamic nucleus on freezing of gait in Parkinson's disease
- Trial name
- STIMSYM (NCT02704195)
- Testing
- Unilateral reduction of stimulation, Chronic Subthalamic nucleus stimulation
- Where
- France
- Volunteers
- 12 people
- Sponsor
- University Hospital, Grenoble
Multiple Sclerosis
Bilateral Anodal Cerebellar tDCS for Multidomain Dysfunctions in Patients With Multiple Sclerosis
The goal of this clinical trial is to learn if brain stimulation can improve movement and daily function in people with multiple sclerosis (MS).
- Trial name
- CerebellertDCS (NCT07555379)
- Testing
- Bilateral Cerebellar Transcranial Direct Current Stimulation (ctDCS)
- Where
- United Arab Emirates
- Volunteers
- 40 people
- Sponsor
- University of Sharjah
Stroke, Walking Impairment
Body Weight-Supported and Virtual Reality Gait Training in Stroke Patients
The aim of this study is to compare the effects of body weight-supported gait training that includes virtual reality-assisted dual-task applications with body weight-supported forward and backward gait training on functional…
- Conditions
- Stroke, Walking Impairment, Balance, Gait Training
- Trial name
- NCT07550270
- Testing
- Virtual Reality-Assisted Gait Training, Backward Gait Training, Forward Gait Training
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Multiple Sclerosis
The Effect of Telerehabilitation Based Pilates Training in Multiple Sclerosis Patients
Multiple Sclerosis (MS) is a chronic inflammatory disease of the central nervous system characterized by myelin, oligodendrocyte, and axon damage.
- Trial name
- NCT04838886
- Testing
- Telerehabilitation-based Pilates Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Gazi University
Hemiparesis/Hemiplegia (One Sided Weakness/Paralysis), Gait Disorder
Isokinetic Strength Training in Hemiparetic Patient With Knee Extension Thrust
The purpose of this study is to assess the impact of an isokinetic strength training of knee flexor and extensor muscles on walking performance in hemiparetic patients with knee extension thrust.
- Trial name
- ISOWALK (NCT05887440)
- Testing
- isokinetic strength training of knee extensor and flexor muscles
- Where
- France
- Volunteers
- 12 people
- Sponsor
- Rennes University Hospital
Ischemic Stroke
Robot-Assisted Gait Therapy in the Subacute Phase of First Ischemic Stroke
Robot-assisted gait training (RAGT) represents a modern concept of neurorehabilitation in stroke patients. This single-center randomized parallel-group neurorehabilitation trial with blinded primary outcome assessment is aimed at…
- Trial name
- NCT04910217
- Testing
- Conventional rehabilitation, Leg/lower body exerciser device intervention., Lokomat intervention
- Where
- Czechia
- Volunteers
- 80 people
- Sponsor
- University Hospital Ostrava
Acute Stroke
Evaluation of Early Standardized Task-Specific Training (ESTT)
A. Specific Aims: 1. There is one specific aim of this study. The aim is to evaluate the effectiveness of early standardized task-specific training (ESTT) in persons with acute stroke. B. Hypothesis: 1.
- Trial name
- ESTT (NCT01774110)
- Testing
- Early standardized task training
- Where
- 4 sites in United States
- Volunteers
- 12 people
- Sponsor
- University of Texas Southwestern Medical Center
Stroke
The Feasibility and Acceptability of a Gait Training Program Based on Telerehabilitation After Stroke
Gait impairments following stroke significantly reduce functional mobility, making walking recovery a primary rehabilitation goal to improve safety, speed, and quality of life while reducing fall risk.
- Trial name
- NCT07623018
- Testing
- STEP-Tech intervention
- Where
- 2 sites in Saudi Arabia
- Volunteers
- 12 people
- Sponsor
- University of Exeter
Stroke, Physical Therapy Modalities
Is the 6-Minute Walking Test Combined With an IMU Useful in Stroke Rehabilitation Assessment?
This Observational study aims at the evaluation of stroke subjects with an inertial measurement unit (IMU) during the execution of a 6-Minute Walking test, to evaluate the associations between the kinematic parameters retrieved…
- Conditions
- Stroke, Physical Therapy Modalities, Gait Analysis
- Trial name
- NCT04529642
- Testing
- Inertial Measurement Unit evaluation
- Where
- Italy
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Stroke
Dynamic Hot Spring Hydrotherapy for Gait Disorders and Balance Function Recovery After Stroke
Our research aims to analyze and compare the improvement of various indicators of gait disorders and balance function before and after dynamic hot spring hydrotherapy and conventional exercise intervention, and clarify the…
- Trial name
- NCT06955182
- Testing
- Dynamic hot spring hydrotherapy intervention, Conventional rehabilitation intervention
- Where
- China
- Volunteers
- 80 people
- Sponsor
- The Second Affiliated Hospital of Kunming Medical University
Parkinson s Disease
Comparison of Immersive and Non-Immersive Virtual Reality Rehabilitation in Parkinson's Disease
Parkinson's disease commonly affects walking ability, balance, mobility, and cognitive function, increasing the risk of falls and reducing independence.
- Trial name
- VR-PD (NCT07659288)
- Testing
- Immersive Virtual Reality, Non-Immersive Virtual Reality
- Where
- Chile
- Volunteers
- 16 people
- Sponsor
- Neuro Group XR Inc.
Acquired Brain Injury, Disorders of Consciousness
Robot-assisted Training After Acquired Brain Injury and Disorders of Consciousness
The goal of this randomised cross-over feasibility trial is to investigate two intensive robot-assisted training therapies in the early rehabilitation phase after acquired brain injury and disorders of consciousness.
- Trial name
- NCT06343415
- Testing
- GAIT-assisted training, STEP-assisted training
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- Christina Kruuse
Stroke
Personalized Post-Stroke Gait Rehabilitation Interventions
The objective of this study is to understand whether certain post-stroke patient subsets, identified from clinical, biomechanical, and neuromuscular characteristics, preferentially respond to different walking rehabilitation…
- Trial name
- NCT07212608
- Testing
- Soft robotic exosuit, Propulsion neuroprosthesis
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Boston University Charles River Campus
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