Clinical trials: Neurologic Gait Disorder
Stroke
Post Stroke Walking Kinematics Using the Honda Walking Assist Robotic Exoskeleton
To investigate the effect of a robotic exoskeleton on kinematics, muscle activity, ground reaction forces and spatiotemporal characteristics during walking in persons post stroke.
- Trial name
- NCT03828214
- Testing
- Robotic exoskeleton for walking assist
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- College of St. Scholastica, Inc.
Spinal Cord Injury, Spinal Cord Injuries
Locomotor Training With Testosterone to Promote Bone and Muscle Health After Spinal Cord Injury
This pilot study will determine the feasibility of implementing a combinatory rehabilitation strategy involving testosterone replacement therapy (TRT) with locomotor training (LT; walking on a treadmill with assistance and…
- Conditions
- Spinal Cord Injury, Spinal Cord Injuries, Trauma, Nervous System, Wounds and Injury
- Trial name
- NCT04460872
- Testing
- Testosterone Enanthate, Locomotor Training
- Where
- 2 sites in United States
- Volunteers
- 21 people
- Sponsor
- North Florida Foundation for Research and Education
Gait Impairment, Cerebral Palsy (CP)
Clinical Investigation to Validate the Safety and Performance of the ABLE Kids Device in Pediatric Patients With Neurological Gait Disorders in a Clinical Setting
The primary objective of the study is to validate the safety and clinical performance of the ABLE Kids device in pediatric patients with neurological gait disorders or muscular weakness during a 10-session gait training program…
- Conditions
- Gait Impairment, Cerebral Palsy (CP), Neuromuscular Diseases (NMD), Spinal Cord Injuries (SCI)
- Trial name
- NCT07745712
- Testing
- ABLE Kids
- Where
- Spain
- Volunteers
- 15 people
- Sponsor
- ABLE Human Motion S.L.
Freezing of Gait, Parkinson Disease
DBS and Levodopa for Treating Freezing of Gait in Parkinson's Disease
Freezing of gait (FoG) is a complex symptom of Parkinson's disease (PD) that cause falls and disability in PD patients, heavily affect patients' autonomy and quality of life.
- Trial name
- NCT06316232
- Testing
- STIM ON plus, MED ON plus
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- IRCCS Istituto delle Scienze Neurologiche di Bologna
Parkinson Disease
Changes in Metabolic Activity, and Gait Function by Dual-task Cognitive Game-based Treadmill Intervention in Parkinson's Disease.
The present proposal will evaluate the neural underpinnings of (a) the decline of mobility function in Parkinson's disease (PD), and (b) the effects of an innovative computer-guided dual-task (DT) mobility training platform…
- Trial name
- CMAGDT (NCT04415775)
- Testing
- Game based treadmill Program, Conventional Gait Rehabilitation
- Where
- Canada
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Stroke
Investigation of Knee Hyperextension and Femoral Cartilage Thickness in Chronic Stroke Patients
It is aimed to measure knee hyperextension and knee joint cartilage thickness in chronic stroke patients and to examine the relationship between the factors affecting knee hyperextension and knee joint cartilage thickness.
- Trial name
- NCT05513157
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Hacettepe University
Stroke
Effects of Voluntary Adjustments During Walking in Participants Post-stroke
People post-stroke retain the capacity to modify walking patterns explicitly using biofeedback and implicitly when encountering changes in the walking environment.
- Trial name
- NCT06034119
- Testing
- Split belt treadmill, Biofeedback
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Chapman University
Cerebral Palsy
Effects of PEDAL Program With and Without EMS On Mobility And Gait In Children With Cerebral Palsy
PEDAL is a program that focuses on juvenile endurance and limb building for kids with cerebral palsy. Studying how PEDAL with and without Electrical Muscle Stimulation (EMS) affects these metrics in an effort to determine whether…
- Trial name
- NCT06460311
- Testing
- PEDAL and EMS, PEDAL
- Where
- Pakistan
- Volunteers
- 22 people
- Sponsor
- Riphah International University
Craniocerebral Trauma, Traumatic Brain Injury
Effect of Passive Gait Training on the Cortical Activity in Patients With Severe Traumatic Brain Injury.
The aim of this study is to determine whether passive gait training increases arousal, demonstrated as changes in EEG (electroencephalogram) activity.
- Conditions
- Craniocerebral Trauma, Traumatic Brain Injury, "Rehabilitation"
- Trial name
- NCT00430703
- Testing
- body weight support treadmill training
- Where
- Denmark
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Parkinson Disease
Effects of Home-based Exercise in Parkinson's Disease
Home-based exercise program focusing on axial rigidity could be used as an adjunct rehabilitation program to improve rotational movement, gait and functional movement associated with axial rigidity in individuals with PD.
- Trial name
- NCT04810897
- Testing
- Exercise
- Where
- Thailand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Acquired Brain Injury, Stroke
Post-Brain Injury Walking and Balance Recovery Program
The purpose of this study is to test the efficacy of a walking and balance training program designed to safely challenge and improve walking performance and balance in relation to walking speed, strength, endurance, and balance…
- Conditions
- Acquired Brain Injury, Stroke, Traumatic Brain Injury
- Trial name
- NCT05934773
- Testing
- KineAssist robotic treadmill
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Stroke Gait Rehabilitation
The Effect of Whole-Body Vibration Therapy Following Botulinum Toxin A Injection on Spasticity and Balance in Stroke Patients
The purpose of this clinical study is to evaluate the effect of Whole Body Vibration (WBV) therapy, applied two weeks after botulinum toxin type A (BoNT-A) injection, on spasticity and balance parameters in individuals with…
- Trial name
- NCT07286435
- Testing
- Whole body vibration therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Uludag University
Stroke
Energy Consumption and Cardiorespiratory Load During Overground Gait Training With a Wearable Exoskeleton After Stroke
To investigate acute metabolic and cardiorespiratory responses during overground gait training with a wearable exoskeleton in persons after stroke
- Trial name
- NCT03367091
- Testing
- Ekso GT gait training with high swing assistance, Ekso GT gait training with neutral swing assistance, Ekso GT gait training with high swing resistance
- Where
- Belgium
- Volunteers
- 1 people
- Sponsor
- Vrije Universiteit Brussel
Spinal Cord Injuries
Neuromodulation of Spinal Locomotor Circuitry to Elicit Stepping After Pediatric Spinal Cord Injury
Spinal cord injury (SCI) results in damage to the descending neural pathways and leads to the immediate dysfunction of multiple physiological systems below the level of injury.
- Trial name
- NCT04077346
- Testing
- Biostim-5 transcutaneous spinal stimulator, Transcutaneous Spinal Stimulator + Activity Based Locomotor Training
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Louisville
Parkinson Disease, Movement Disorder, Functional
The Effects of fNIRS-based Neurofeedback Training on Balance and Gait in Parkinson's Disease
A cross-sectional study (part 1) aims to investigate the influence of fatigue on the MI ability in PD compared to healthy controls.
- Trial name
- NCT05800470
- Testing
- fNIRS-based neurofeedback with motor imagery, Kinesthetic motor imagery, Motor training
- Where
- Taiwan
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Acquired Brain Injury, Cerebral Palsy
The Effectiveness of Robotic Gait Training in Children With Neurological Impairment
The recovery of walking ability is one of the primary rehabilitation goals for children with neurological impairment. The aim of the study is to investigate the clinical effectiveness of rehabilitation treatments based of…
- Trial name
- NCT03828110
- Testing
- Robotic Assisted Gait Training (Lokomat), Physiotherapy
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- IRCCS Eugenio Medea
Spinal Cord Injuries, Paraplegia
Gait Training for Individuals With Paraplegia Using the H-MEX Exoskeleton
This study evaluates the feasibility and effects of H-MEX powered exoskeleton in individuals with paraplegia as a result of spinal cord injury.
- Trial name
- NCT04055610
- Testing
- Gait training using H-MEX exoskeleton
- Where
- South Korea
- Volunteers
- 10 people
- Sponsor
- Hanyang University Seoul Hospital
Parkinson Disease
Effect of Simultaneous Dual Stimulation on Freezing of Gait in Parkinson's Disease
The purpose of this study is to investigate the effect of dual-mode non-invasive brain stimulation (NIBS) with high-frequency repetitive transcranial magnetic stimulation (rTMS) over the primary motor cortex of the lower leg and…
- Trial name
- NCT02850159
- Testing
- rTMS and tDCS, rTMS
- Volunteers
- 32 people
- Sponsor
- Samsung Medical Center
Multiple Sclerosis, Multiple Sclerosis (MS) - Relapsing-remitting
Acute Intermittent Hypoxia Combined With Gait Training in Multiple Sclerosis
This interventional, randomized, sham-controlled study will examine whether Acute Intermittent Hypoxia (AIH) delivered immediately before Myoelectric Interface Neurorehabilitation Training (MINT)-based locomotor training improves…
- Conditions
- Multiple Sclerosis, Multiple Sclerosis (MS) - Relapsing-remitting, Multiple Sclerosis (MS) Primary Progressive, Multiple Sclerosis (MS) Secondary Progressive
- Trial name
- MINT (NCT07631923)
- Testing
- Acute Intermittent Hypoxia (AIH), Myoelectric Interface Neurorehabilitation Training (MINT)
- Volunteers
- 35 people
- Sponsor
- Shirley Ryan AbilityLab
Parkinson's Disease
Pedunculopontine Nucleus Stimulation for Gait Disorders in Parkinson's Disease
The appearance of postural instability and gait disorders is a major turning point in the evolution of Parkinson's disease (PD).
- Trial name
- NCT02055261
- Testing
- Low frequency DBS of the pedunculopontine nucleus
- Where
- France
- Volunteers
- 6 people
- Sponsor
- Pitié-Salpêtrière Hospital
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