Clinical trials: Neurologic Signs
Anxiety, Pain
The Effect of Virtual Reality Glasse on Pain and Anxiety During Episiotomy Repair
Episiotomy is one of the common surgical operations that can cause anxiety in women and have side effects such as pain. Nerve blockades with analgesic effects such as lidocaine used during episiotomy repair or the use of…
- Conditions
- Anxiety, Pain, Episiotomy Wound, Midwifery
- Trial name
- NCT05198908
- Testing
- VR group, Skin to skin group
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Kırklareli University
Urolithiasis
Effect of Ureteral Access Sheath Use on Postoperative Pain Level in Patients Undergoing RIRS
This study will include patients aged between 18 and 70 who will undergo retrograde intrarenal surgery (RIRS) due to renal stone(s).
- Trial name
- NCT02501525
- Testing
- RIRS with ureteral access sheath, RIRS without ureteral access sheath
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Selcuk University
Sleep, Sleep Deprivation
Sleep Duration Required to Restore Performance During Chronic Sleep Restriction
The purpose of this study is to test the hypothesis that sleep and performance depend on length of time awake, length of time asleep, the amount of sleep over several sleep episodes, and circadian phase.
- Conditions
- Sleep, Sleep Deprivation, Insufficient Sleep Syndrome
- Trial name
- NCT01581125
- Testing
- Sleep:wake 1, Sleep:wake 2
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Coronary Heart Disease, Angina Pectoris
Safety Study of Kudiezi(Yueanxin,a Chinese Medicine Injection)Used in Hospitals in China
This study was advocated by institute of Basic Research in Clinical Medicine,China Academy of Chinese Medical Sciences in October 2011.
- Conditions
- Coronary Heart Disease, Angina Pectoris, Stroke
- Trial name
- NCT01781676
- Where
- China
- Volunteers
- 30,000 people
- Sponsor
- China Academy of Chinese Medical Sciences
Progressive Supranuclear Palsy, Parkinson's Disease
Postural Instability in Progressive Supranuclear Palsy
The purpose of this study is to better understand why individuals with Progressive Supranuclear Palsy (PSP) fall. Understanding the mechanism of gait and balance dysfunction in individuals with PSP may provide us with important…
- Trial name
- NCT01563276
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Back Pain, Lower Extremity Pain
The Feasibility of Using Neuroscience Education in Adults Over 65 Years Old With Chronic Low Back and/or Lower Extremity Pain
This is a pilot study to determine if neuroscience education is acceptable to adults over 65 and if it can have an impact on pain, pain beliefs and gait speed
- Trial name
- NCT02449876
- Testing
- Neuroscience Education
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- State University of New York - Upstate Medical University
Chronic Post Surgical Pain, Functional Recovery
Incidence of Chronic Pain in Patients Undergoing Knee Arthroplasty Within a Fast-Track Protocol
The goal of this study is to learn about pain after knee replacement surgery. The surgery uses a fast-recovery program called Enhanced Recovery After Surgery (ERAS).
- Conditions
- Chronic Post Surgical Pain, Functional Recovery, ERAS, Chronic Opioid Use
- Trial name
- NCT07673276
- Where
- Belgium
- Volunteers
- 153 people
- Sponsor
- University Hospital, Ghent
Anaesthesia
Effect of Parecoxib on Post-craniotomy Pain
Aim of this trial: To investigate whether post-craniotomy analgesia with (i) intravenous (IV) parecoxib plus intravenous paracetamol is superior to (ii) intravenous paracetamol alone.
- Trial name
- NCT00455117
- Testing
- Intravenous Parecoxib ('Dynastat' Pfizer)
- Where
- Australia
- Volunteers
- 130 people
- Sponsor
- Melbourne Health
Coronary Artery Bypass Graft Surgery (CABG), Pain
Effect of Swedish Hand Massage on Pain in Patients Undergoing CABG Surgery
Coronary Artery Bypass Grafting (CABG) surgery is performed commonly today. Heart surgery performed on more than two million individuals every year leads patients experience severe postoperative pain for causes such as cutting of…
- Conditions
- Coronary Artery Bypass Graft Surgery (CABG), Pain, Pain Management, Nursing
- Trial name
- NCT06688617
- Testing
- Swedish Hand Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Istanbul University - Cerrahpasa
Pain, Pain, Postoperative
Opioid-Free Orthopaedics
The goal of this investigation is to compare effectiveness of this multimodal regimen at controlling postoperative pain with and without the use of opioid medications.
- Trial name
- NCT04659317
- Testing
- Oxycodone 5 mg Oral Tablet
- Where
- 3 sites in United States
- Volunteers
- 80 people
- Sponsor
- Emory University
Pain
Efficacy and Safety of Ibuprofen in Patients With Ankle Injuries
The objective of the study is to evaluate the efficacy and safety of Ibuprofen in patients with ankle injuries.
- Trial name
- NCT01563289
- Testing
- Ibuprofen
- Where
- Finland
- Volunteers
- 62 people
- Sponsor
- Orion Corporation, Orion Pharma
Pain, Fatigue
The Effect of Shower on Birth Pain, Postpartum Fatigue and Comfort
According to the definition of the International Association for the Study of Pain, pain; It is an unpleasant sensory and emotional sensation and behavior related to the individual's past experiences, caused by real or potential…
- Trial name
- NCT06183957
- Testing
- hydrotherapy group
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kırklareli University
Opioid Use, Pain
Hip Arthroscopy Postoperative Opioid Demands
This study will be a prospective, single-blinded, randomized controlled trial (RCT), investigating the influence of the number of opioid pills prescribed following primary hip arthroscopy.
- Conditions
- Opioid Use, Pain, Femoral Acetabular Impingement, Labral Tear, Glenoid
- Trial name
- NCT04094701
- Testing
- Control Group Regimen, Opioid reduced regimen
- Where
- United States
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Ménière's Disease, Vestibular Migraine
The CAVA Multicentre Dizziness Trial
The CAVA trial is a diagnostic accuracy multicentre device trial which aims to quantify the extent to which the CAVA system can differentiate three common inner-ear causes of dizziness: Ménière's disease, vestibular migraine and…
- Conditions
- Ménière's Disease, Vestibular Migraine, Benign Paroxysmal Positional Vertigo (BPPV)
- Trial name
- CAVA 2 (NCT05984901)
- Testing
- The continuous ambulatory vestibular assessment (CAVA) system
- Where
- United Kingdom
- Volunteers
- 4 people
- Sponsor
- Norfolk and Norwich University Hospitals NHS Foundation Trust
Neck Pain
Effectiveness of DN Versus TU Along With Routine PT in Patients With for Chronic Neck Pain RCT
To determine the effectiveness of dry needling and therapeutic ultrasound for the treatment of chronic neck pain
- Trial name
- NCT05868512
- Testing
- Dry needling, Therapeutic ultrasound
- Where
- Pakistan
- Volunteers
- 31 people
- Sponsor
- Superior University
Motivation, Apathy
Motivation and Methylphenidate
The purpose of this study is to evaluate the impact of methylphenidate, a mixed dopaminergic and noradrenergic agent, onto the different components of motivation: decision-making, effort allocation and instrumental learning.
- Conditions
- Motivation, Apathy, Impulsive Behavior
- Trial name
- MBB_MPH (NCT03190681)
- Testing
- Ritalin (methylphenidate)10Mg Tablet
- Where
- France
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Pain, Acute
Open-Label Placebo for Non-Specific Pain in the ED
The aim of this study is to assess whether an intervention with open-label placebo (OLP) for non-specific pain in the emergency department is feasible.
- Trial name
- OLP_EM (NCT06408519)
- Testing
- Ibuprofen 400 mg
- Where
- Switzerland
- Volunteers
- 57 people
- Sponsor
- Bruno Minotti
Postoperative Pain, Acute
Comparison of Transversus Abdominis Plane and Erector Spinae Plane Blocks for Pain Control After Renal Laparoscopy
The goal of this study is to compare the analgesic efficacy of ultrasound-guided transversus abdominis plane (TAP) block versus erector spinae plane block (ESPB) in adult patients undergoing laparoscopic renal surgeries.
- Trial name
- TAP-ESPB (NCT07781930)
- Testing
- TAP Block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Atrial Fibrillation (AF)
Safety in Adult Participants With Atrial Fibrillation Who Are Treated With Anticoagulation
This study is researching experimental drugs called REGN7508 and REGN9933. The study is focused on participants who have atrial fibrillation, which means that the heart beats too fast and unevenly.
- Trial name
- ROXI-ATLAS (NCT07175428)
- Testing
- REGN7508, REGN9933, Apixaban
- Where
- 89 sites in United States, Argentina and 2 more
- Volunteers
- 1,200 people
- Sponsor
- Regeneron Pharmaceuticals
Acute Pain
A Study to Evaluate the Efficacy and Safety of K-285 Compared With Menthol Gel for the Treatment of Delayed Onset Muscle Soreness (DOMS) in the Lower Extremity
The purpose of this study to evaluate the efficacy and safety of K-285 compared with menthol gel for the treatment of delayed onset muscle soreness (DOMS) in the lower extremity.
- Trial name
- NCT04484428
- Testing
- K-285, Menthol
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Kowa Research Institute, Inc.
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