Clinical trials: Neurologic Signs
TBI Traumatic Brain Injury, Enteral Nutrition Therapy
Effect of Enteral Formula (Commercial vs. Homemade) on Muscle Mass in Trauma Brain Injury
This randomized controlled clinical trial aims to determine whether there are differences in muscle mass (MM) in patients with traumatic brain injury who receive enteral nutrition based on polymeric formulas (homemade formula…
- Conditions
- TBI Traumatic Brain Injury, Enteral Nutrition Therapy, Critical Illness
- Trial name
- NCT06949163
- Testing
- Homemade formula, Commercial formula
- Where
- Mexico
- Volunteers
- 39 people
- Sponsor
- Hospital General "Dr. Miguel Silva" de Morelia
Chronic Knee Pain, Fibromyalgia
Investigating the Role of Central Pain Hypersensitivity in Skeletal Muscle Neural Drive
Background: pain lasting for 12 weeks or beyond, which is often referred to as chronic pain, is common for people living with musculoskeletal conditions (e.g. arthritis, low back pain and fibromyalgia).
- Trial name
- Pain-Drive (NCT07281651)
- Testing
- Central Pain Hypersensitivity
- Where
- United Kingdom
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Vision Impairment
Restricted Useful Field View as a Risk Factor in Older Adults
The relationship between Useful Field of Vision (UFOV) and falls taken by the elderly will be investigated. UFOV is a test which measures visual attention.
- Trial name
- NCT00013351
- Testing
- Prevention of Falls
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- US Department of Veterans Affairs
Liver Cirrhosis
Branched Chain Aminoacid Supplementation in Patients With Liver Cirrhosis
Malnutrition is a frequent complication in patients with liver cirrhosis. Most patients have decreased dietary intake due to ascites, hepatic encephalopathy and pro-inflammatory cytokines.
- Trial name
- NCT02023229
- Testing
- Branched-chain aminoacids, High-fiber high protein diet
- Where
- Mexico
- Volunteers
- 68 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Chronic Widespread Pain
Fecal Microbiota Transplantation for Patients With Chronic Widespread Pain
This study aims to explore the effect of Fecal Microbiota Transplantation (FMT) on the clinical symptomatology in Chronic Widespread Pain (CWP), to assess the acceptability, tolerability, and safety of FMT in patients with CWP…
- Trial name
- NCT05700331
- Testing
- Fecal Microbiota Transplantation, Sigmoidoscopy
- Where
- Hong Kong
- Sponsor
- Chinese University of Hong Kong
Sickle Cell Disease, Pain
Effect of EMDR for Reduction of Pain Interference in Children With Sickle Cell Disease
Children with sickle cell disease may experience frequent painful episodes. This, together with the traumatic experiences during a hospitalization, can lead to the development of posttraumatic stress reactions.
- Conditions
- Sickle Cell Disease, Pain, Pain, Chronic Disease
- Trial name
- RELAX (NCT07001631)
- Testing
- Eye Movement Desensitization and Reprocessing (EMDR)
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Age-related Hearing Loss, Cognitive Decline
Study of Cognitive Reserve Disorder Affecting Depression in Aged Related Hearing Loss Via Rest State EEG
In this study, patients with aged-related hearing loss with depression and without depression were evaluated by audiometry (pure tone audiometry and speech audiometry), cognitive function assessment (MMSE scale for simple mental…
- Conditions
- Age-related Hearing Loss, Cognitive Decline, Depression
- Trial name
- NCT05892731
- Testing
- with depression, without depression
- Where
- China
- Volunteers
- 44 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Muscle Fatigue (C23.888.592.612.612), Muscle Weakness or Atrophy
A Biomechanical Study of Collaborative FES on Lower Limb Motor Function in the Elderly
This study will first conduct a precise assessment of the differences in muscle coordination among the elderly through muscle synergy analysis; then, based on this, it will extract abnormal synergy patterns and muscle activation…
- Trial name
- NCT07245602
- Testing
- Collaborative Functional Electrical Stimulation, Traditional functional electrical stimulation
- Volunteers
- 30 people
- Sponsor
- Chen Xuan
Deep Learning
Automated Detection and Diagnosis of Pathological DRGs in PHN Patients Using Deep Learning and Magnetic Resonance
Here, this study aimed to develop an automated system for detecting and diagnosing lesion DRGs in PHN patients based on deep learning.
- Trial name
- NCT06274502
- Testing
- YOLOv8
- Where
- 2 sites in China
- Volunteers
- 41 people
- Sponsor
- Huazhong University of Science and Technology
Progressive Supranuclear Palsy, Brain Diseases
Personalized Parkinson Project PSP Cohort
There is an urgent need for the development of digital progression biomarkers, which are sensitive to detect small, but potentially clinically relevant changes in the disease course.
- Conditions
- Progressive Supranuclear Palsy, Brain Diseases, Neurodegenerative Diseases, Movement Disorders
- Trial name
- PPP-PSP (NCT05501431)
- Testing
- Verily Study Watch
- Where
- Netherlands
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Pain
A Study of Cannabis Based Medicine Extracts and Placebo in Patients With Pain Due to Spinal Cord Injury
A study to investigate the effects of sublingual cannabis based medicine extracts on neuropathic pain associated with spinal cord injury.
- Trial name
- NCT01606202
- Testing
- GW-1000-02
- Where
- United Kingdom
- Volunteers
- 116 people
- Sponsor
- Jazz Pharmaceuticals
Chronic Fatigue Syndrome
Transcutaneous Vagus Nerve Stimulation as a Complementary Therapy to Exercise in Chronic Fatigue
Chronic fatigue is enhanced by adapted physical activity (APA) programs. Patients consulting on St Etienne hospital and suffering from fibromyalgia and long Covid benefit from a 4-6 week APA program, with 2 sessions per week.
- Trial name
- PAF-tVNS (NCT06170645)
- Testing
- APA program, Active transcutaneous VNS
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Cervical Cancer, Endometrial Cancer
Epidural Analgesia or Patient-Controlled Analgesia in Treating Patients Who Have Undergone Surgery for Gynecologic Cancer
RATIONALE: Giving pain medication into the space between the wall of the spinal canal and the covering of the spinal cord or giving it into a vein may help lessen pain caused by cancer surgery.
- Conditions
- Cervical Cancer, Endometrial Cancer, Fallopian Tube Cancer, Ovarian Cancer
- Trial name
- NCT00295945
- Testing
- fentanyl citrate, hydromorphone hydrochloride, ropivacaine hydrochloride
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- University of California, San Francisco
Sarcopenia
Increase of Handgrip Strength After the Use of Removable Partial Dentures.
A common goal of the health professions is to keep the elderly functional, preventing sarcopenia and frailty. Is there an association between handgrip strength in partially edentulous elderlies after completing their dentition…
- Trial name
- NCT04606745
- Where
- Chile
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Comisión Nacional de Investigación Científica y Tecnológica
Radiculopathy, Musculoskeletal Diseases
Clinical Effectiveness of High-Intensity Laser Therapy in Patients With Cervical Radiculopathy:
This investigation aims to investigate the effect of high intensity laser therapy on radicular symptoms, neuropathic pain, cervical range of motion and quality of life in patients with cervical radiculopathy compared to cervical…
- Conditions
- Radiculopathy, Musculoskeletal Diseases, Cervical Pain, Cervical Radicular Pain
- Trial name
- NCT04734977
- Testing
- High-intensity laser therapy (HILT), Therapeutic Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Afyonkarahisar Health Sciences University
Post Herpetic Neuralgia
Efficacy, Tolerability, and Safety of NXN-462 in Patients With Post-Herpetic Neuralgia
The purpose of this study is to investigate whether NXN-462, a selective nNOS inhibitor, is effective in reducing pain levels in patients with post-herpetic neuralgia.
- Trial name
- NCT01748877
- Testing
- NXN-462
- Where
- 25 sites in United States, Canada
- Volunteers
- 188 people
- Sponsor
- NeurAxon Inc.
Pain
The Effect of Warming and Vibration Applications on Pain in Newborns
This study aimed to determine the effects of warming and vibration applications on pain during heel blood collection in newborns. H1: Warming application has a positive effect on pain during heel blood collection in newborns.
- Trial name
- NCT06607575
- Testing
- Control group, Warming, Vibration
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Endometriosis
BGS649 Monotherapy in Moderate to Severe Endometriosis Patients
This study will assess the safety and tolerability of BGS649 in women with moderate to severe endometriosis.
- Trial name
- NCT01190475
- Testing
- Active treatment with a high dose of BGS649, Active treatment with a low dose of BGS649
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Mereo BioPharma
Pain
Do Emotions Affect Mechanical Pain Thresholds?
The purpose of this study is to investigate if different emotional states could influence mechanical pain thresholds.
- Trial name
- DEAMPT (NCT06074575)
- Testing
- Emotion induction
- Where
- Sweden
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Linnaeus University
Cirrhosis, Hepatic Encephalopathy
Brain Energy Metabolism in Patients With Chronic Liver Disease and Impaired Central Nervous System
The purpose of the current study is to look into the pathogenesis of a severe medical condition causing acute episodes on the central nervous system as seen in majority of patients with liver cirrhosis.
- Trial name
- NCT00424957
- Where
- Denmark
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.