Clinical trials: Neurologic Signs
Breast Cancer
Musculoskeletal Pain in Postmenopausal, Early Breast Cancer Patients Receiving Aromatase Inhibitor Therapy - A Pilot Study
In 2005, the EBCIG demonstrated the efficacy of tamoxifen in improving overall survival in hormone receptor positive breast cancers.
- Trial name
- AIMS (NCT00653718)
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Cholecystitis, Pain
Transmuscular Quadratus Lumborum Block for Laparoscopic Cholecystectomy
The TQL block may prove a valuable method for treating postoperative pain following scopic removal of the gall bladder. The trial will compare active TQL block versus placebo TQL block after said operation.
- Trial name
- TQL (NCT02225418)
- Testing
- Ropivacaine, saline
- Where
- Denmark
- Sponsor
- Jens Borglum Neimann
Hepatic Encephalopathy, Cirrhosis
Albumin Infusion Effects in Mortality in Patients With Cirrhosis and Hepatic Encephalopathy
To assess whether albumin administration after an episode of hepatic encephalopathy (≥ grade II) improves survival at 90 days (mortality endpoint treated as a composite endpoint death and/ or liver transplantation).
- Trial name
- BETA (NCT02401490)
- Testing
- Human albumin
- Where
- 7 sites in Spain
- Volunteers
- 128 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Low Back Pain
Efficacy of the Electronic Acupuncture Shoes: A Clinical Trial for Chronic Low Back Pain
This randomized , double-blind, parallel-arm clinical trial was designed to study the efficacy and safety of the "Electronic Acupuncture Shoes" treatment on chronic low back pain patients.
- Trial name
- EAS (NCT02468297)
- Testing
- Electronic Acupunture Shoes, Ibuprofen
- Volunteers
- 60 people
- Sponsor
- Chen Yu Sheng
Irreversible Pulpitis
Dexketoprofen Trometamol in Postoperative Endodontic Pain
The purpose of this study is to investigate the analgesic efficacy of multiple doses of Dexketoprofen Trometamol 25 mg on postoperative pain following emergency endodontic treatment in teeth with irreversible pulpitis, using as…
- Trial name
- DTPEP (NCT02086097)
- Testing
- Dexketoprofen trometamol, Ibuprofen
- Where
- Mexico
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Daniel Chavarría Bolaños
Postoperative Pain
Administration of Pre-Operative Gabapentin to Patients Undergoing Laparoscopy
The purpose of this study is to prospectively determine the influence of immediate pre-operative gabapentin administration on acute postoperative pain.
- Trial name
- Gabapentin (NCT02359110)
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Tinnitus, Subjective
Temporomandibular Dysfunction in Patients With Tinnitus: Assessment and Treatment
TMD treatment, based on state of the art knowledge derived from clinical studies will be applied in patients with tinnitus and TMD.
- Trial name
- NCT03209297
- Testing
- TMD treatment: physiotherapy and/or occlusal splints
- Where
- Belgium
- Volunteers
- 120 people
- Sponsor
- Universiteit Antwerpen
Obesity, Morbid, Back Pain
THE EFFECT OF FAST WEIGHT EFFICIENCY AFTER LAPAROSCOPIC SLEEVE GASTRECTOMY ON THE COBB ANGLE IN MORBID OBESE PATIENTS
Obesity has become an increasingly common health problem today. In this context, although many anatomical, physiological and metabolic problems arising from obesity in morbid obese patients are tried to be solved in daily…
- Conditions
- Obesity, Morbid, Back Pain, Scoliosis
- Trial name
- NCT04844320
- Testing
- Cobb angle measurements
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Cardiovascular Diseases, Heart Diseases
Postmenopausal Progestins, MI and Stroke
To evaluate the cardiovascular effects of postmenopausal hormone replacement therapy and the suspected beneficial effects on myocardial infarction and stroke.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Coronary Disease, Cerebrovascular Accident
- Trial name
- NCT00005220
- Sponsor
- University of Washington
Multiple Sclerosis, Relapse
Coagulation/Complement Activation and Cerebral Hypoperfusion in Relapsing-remitting Multiple Sclerosis
This is a multi-center, prospective, controlled study. MS patients (1° group: 30 patients in relapse; 2° group: 30 patients in remission) and age/sex-matched healthy controls (3° group: 30 subjects) will be enrolled in the study.
- Trial name
- NCT04380220
- Testing
- Blood samples and processing
- Where
- 3 sites in United States, Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Regina Elena Cancer Institute
Ischemic Attack, Transient
Cognitive and Physical Functions in Patients With Transient Ischemic Attack. A Randomized Controlled Trial of Physical Activity on Prescription up to One Year After the Event
The purpose of this study is to determine whether Physical Activation on Prescription can help patients with TIA to become more physically active.
- Trial name
- NCT01509924
- Testing
- Physical activation on Prescription
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Tiohundra AB
Fracture
Cannabidiol After Multi-Trauma for Pain and Opioid Therapy
The aim of this project is to investigate the therapeutic potential and safety of acute Cannabidiol (CBD) treatment on longitudinal pain symptoms, and to assess potential interactions with pain mediators including opioids and sex…
- Trial name
- CAM-POT (NCT06448923)
- Testing
- Cannabidiol
- Where
- Canada
- Volunteers
- 225 people
- Sponsor
- Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal
Visual Impairments
Traditional Exercise RCT in Visually Impaired Adults
This study aims to investigate the benefits and underlying mechanisms of traditional exercise interventions on the physical and mental health of individuals with visual impairments.
- Trial name
- NCT07265024
- Testing
- Taichi, Baduanjin
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Northeast Normal University
Patients Undergoing Arthroscopic Knee Surgery
Evaluation of the Effectiveness of iPACK and Adductor Canal Blocks on Patients Undergoing Arthroscopic Knee Surgery
Arthroscopic knee surgery is one of the most commonly performed procedures in orthopedic surgery. More than 50% of patients experience moderate to severe pain after the operation.
- Trial name
- NCT07002580
- Testing
- IPACK and adductor canal block with Bupivacaine 0.25%, Spinal Anesthesia with Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Sakarya University
Language Development Disorders
Kindergarten Children Acquiring Words Through Storybook Reading
Children with Specific Language Impairment (SLI) are slower to learn new words than their peers, placing them at risk for academic failure.
- Trial name
- KAWStory (NCT03586479)
- Testing
- Interactive storybook reading
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Kansas
Fibromyalgia
Effects and Mechanisms of Pain Neuroscience Education in Patients With Fibromyalgia
This randomized controlled trials study aims, first, to determine the effectiveness of a nurse-led PNE program designed by a multidisciplinary team, compared with an active control group on pain intensity, fibromyalgia (FM)…
- Trial name
- NCT06097091
- Testing
- Self-management education, pain neuroscience education
- Where
- Taiwan
- Volunteers
- 98 people
- Sponsor
- Taipei Medical University
Postoperative Pain
Quadratus Lumborum Block for Total Abdominal Hysterectomy
Procedure specific postoperative pain management (PROSPECT) guidelines for abdominal hysterectomy published in 2006 recommended laparoscopic or vaginal hysterectomy as a preferred surgical technique.
- Trial name
- NCT05765318
- Testing
- QLB
- Where
- Serbia
- Volunteers
- 60 people
- Sponsor
- Clinical Center Niš
BIPOLAR DISORDER
Involvement of the Sodium Pump and Endogenous Digitalis-like Compounds in Bipolar Disorder
This study deals with the possible molecular mechanisms that underlie the etiology of bipolar disorders (BD). Previous studies have implicated Na+, K+-ATPase and endogenous digitalis-like compounds (DLC) in the depressive state…
- Trial name
- NA\K-MANIA (NCT01322113)
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Hadassah Medical Organization
Primary Central Nervous System Lymphoma, Recurrent Cancer
Pembrolizumab, Ibrutinib and Rituximab in PCNSL
This research study is evaluating a combination therapy of 3 drugs as possible treatments for recurrent primary central nervous system lymphoma (PCNSL).
- Conditions
- Primary Central Nervous System Lymphoma, Recurrent Cancer, Refractory Cancer, Relapsed Cancer
- Trial name
- NCT04421560
- Testing
- Ibrutinib, Pembrolizumab, Rituximab
- Where
- 4 sites in United States
- Volunteers
- 37 people
- Sponsor
- Dana-Farber Cancer Institute
Gonarthrosis
Efficacy of Ultrasound-Guided Genicular Nerve Radiofrequency Ablation Therapy
The main symptom of knee osteoarthritis, which occurs after damage to the joint cartilage with age, is pain, but this symptom often becomes chronic.
- Trial name
- NCT06914960
- Testing
- 2-point Radiofrequency Ablation, 3-point Radiofrequency Ablation, 5-point Radiofrequency Ablation
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Bengu Turemenogullari
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