Clinical trials: Neurologic Signs
Chronic Pain, Veterans
Co-Adaptation of an Digital Pain Management Program for Canadian Veterans
The goal of this study is to gather feedback from Canadian Veterans living with chronic pain, and clinicians serving Canadian Veterans, on an existing digital psychology program for self-management of chronic pain delivered…
- Trial name
- ADOPTCanVets (NCT07818980)
- Testing
- Self-Guided Digital Acceptance and Commitment Therapy Program
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- University Health Network, Toronto
Pain, Postoperative
Comparing Anugel With Gelatine Sponges for Pain Management After Hemoroidectomy
Post-operational pain is the most common problem relating to haemorrhoidectomy. This study aims to evaluate the postoperative effects of Anugel a hydrogel impregnated multi component sponge vs gelatine sponge comparatively.
- Trial name
- NCT04057079
- Testing
- Anugel, Hydrogel sponge, Gelatine Sponge
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Deep Life Medical Ltd
Right-to-left Shunt, Migraine
Registry of Right-to-left Shunt Detection by Contrast-enhanced Transcranial Doppler in Chinese Population
The purpose of the study is to evaluate the prevalence and extent of right-to-left shunt (RLS) in Chinese migraineurs, and the morbidity of silent cerebral infarction in migraineurs.
- Conditions
- Right-to-left Shunt, Migraine, Cerebral Infarction
- Trial name
- NCT02425696
- Where
- China
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- Yingqi Xing
Gastric Emptying, Gastroparesis
Gastric Emptying Recovery After GLP-1 RA Cessation
Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) can delay gastric emptying and may increase residual gastric contents before general anesthesia.
- Conditions
- Gastric Emptying, Gastroparesis, Preoperative Care
- Trial name
- NCT07360262
- Testing
- Preoperative gastric ultrasound
- Where
- 2 sites in South Korea
- Volunteers
- 186 people
- Sponsor
- Wonkwang University Hospital
Benign Paroxysmal Positional Vertigo, Multiple Sclerosis
Epley Manoeuvre in Participants With Multiple Sclerosis Diagnosed From Benign Paroxysmal Positional Vertigo
Vertigo, dizziness and control postural disturbance are one of the most disabling symptoms in Multiple Sclerosis. These could be caused by a peripheral or central vestibular disorder.
- Trial name
- NCT04578262
- Testing
- Epley Manoeuvre
- Volunteers
- 80 people
- Sponsor
- University of Seville
Temporomandibular Disorder, Depression
Determination of Chronic Pain, Anxiety, Depression and Perceived Stress in Adults With Temporomandibular Disorders
The aim of the study was to asses levels and relationship of chronic pain, anxiety, depression and perceived stress in TMD patients .
- Conditions
- Temporomandibular Disorder, Depression, Anxiety, Pain
- Trial name
- NCT05183503
- Testing
- DC/TMD examination
- Where
- Poland
- Volunteers
- 219 people
- Sponsor
- Wroclaw Medical University
Delayed-onset Muscle Soreness, Sleep
Sleep and Delayed-onset Muscle Soreness
There is a need for further experimental research in order to gain a more in-depth understanding of this vicious cycle of pain and sleep disorders.
- Conditions
- Delayed-onset Muscle Soreness, Sleep, Pain
- Trial name
- NCT06699186
- Testing
- Sleep, Non-sleep
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Cerebral Palsy
EXOPULSE Mollii Suit & Cerebral Palsy
Spasticity is a frequent and debilitating symptom in patients with cerebral palsy. It can alter the patients' balance, mobility, as well as their quality of life (QoL).
- Trial name
- EXOCEP (NCT06266286)
- Testing
- EXOPULSE MOLLII SUIT (active)
- Where
- 4 sites in France
- Volunteers
- 32 people
- Sponsor
- Institut De La Colonne Vertebrale Et Des Neurosciences
Fibromyalgia, Pain, Chronic
Psychobiological Mechanisms Underlying Chronic Pain
Pain is a powerful motivator of behavior and it is more than the perception of nociceptive input. It is a complex experience that comprises different components: sensory discriminative, emotional-motivational and cognitive…
- Conditions
- Fibromyalgia, Pain, Chronic, Chronic Pain, Widespread
- Trial name
- NCT04674670
- Testing
- Bromocriptine Mesylate Capsules, Amisulpride 400 MG
- Where
- Switzerland
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- susanne becker
Cervical Pain, Pelvic Pain
Tenaculum Pain Control Study
The purpose of this clinical trial is to evaluate the effect of an intracervical lidocaine injection versus topical lidocaine gel on the pain experienced by patients undergoing tenaculum application to the cervix during office…
- Trial name
- NCT01421641
- Testing
- Intracervical Lidocaine Injection, Topical Lidocaine Gel
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Chronic Widespread Pain, Sleep Disturbance
Sleep Disturbances and Chronic Widespread Pain
Chronic widespread pain (CWP), defined as long-lasting pain in multiple body regions, has a prevalence of 10-14% in Europe and is associated with other physical symptoms such as fatigue and cognitive problems.
- Trial name
- POSEIDON (NCT03908905)
- Testing
- Polysomnography
- Where
- Sweden
- Volunteers
- 96 people
- Sponsor
- Uppsala University
Hearing Loss, Sensorineural, Hearing Loss, Cochlear
Usability of the Intracochlear Catheter INCAT - a Feasibility Study
This is a feasibility study for a inner ear catheter which will be used to apply steroids to the inner ear. It will be used on nearly deaf patients during their surgery, when they receive an implant that will restore the hearing.
- Trial name
- INCAT (NCT06218966)
- Testing
- intracochlear catheter
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Sunnybrook Health Sciences Centre
Pain
Effect of Dry Needling on Myofascial Trigger Point
Myofascial trigger point is one of the most common causes of musculoskeletal disorders. Myofascial trigger point in upper trapezius has been reported as a symptom in patients with neck and upper thoracic pain.
- Trial name
- NCT02107456
- Testing
- Dry Needling
- Where
- Iran
- Volunteers
- 33 people
- Sponsor
- University of Social Welfare and Rehabilitation Science
Hearing Impairment
Clinical Evaluation of the Nuance Audio Hearing Aid in Adults With Mild to Moderate Hearing Difficulties
The research will produce clinical effectiveness performance metrics using standardised procedures of the Nuance Audio hearing device.
- Trial name
- NCT07100522
- Testing
- Hearing aid in spectacle frame form factor, hearing aid
- Where
- Australia
- Volunteers
- 21 people
- Sponsor
- Luxottica Group S.p.A.
Sarcopenia, Muscle Weakness
Effects of Mobility Dose in Surgical Intensive Care Unit Patients
The primary aim of this study is to assess if the mobility dose that patients receive in the surgical intensive care unit (SICU) predicts adverse discharge disposition (primary endpoint), and muscle wasting diagnosed by bedside…
- Conditions
- Sarcopenia, Muscle Weakness, Critical Illness
- Trial name
- MQS (NCT03196960)
- Where
- 3 sites in United States, Germany and 1 more
- Volunteers
- 150 people
- Sponsor
- Massachusetts General Hospital
Drug-Resistant Epilepsy, Focal-Onset Seizures
Study to Test the Safety and Efficacy of Padsevonil as Adjunctive Treatment of Focal-onset Seizures in Adult Subjects With Drug-resistant Epilepsy
The purpose of the study is to evaluate the long-term safety and tolerability of Padsevonil administered at individualized doses as adjunctive treatment for subjects with drug-resistant epilepsy.
- Trial name
- NCT03370120
- Testing
- Padsevonil
- Where
- 156 sites in United States, Australia and 25 more
- Volunteers
- 406 people
- Sponsor
- UCB Biopharma SRL
Postoperative Pain, Cholecystectomy, Laparoscopic
M-TAPA vs ESPB for Postoperative Analgesia After Laparoscopic Cholecystectomy
Postoperative pain after laparoscopic cholecystectomy can negatively affect patient comfort, recovery, and opioid consumption. Regional abdominal wall blocks are commonly used as part of multimodal analgesia to improve…
- Trial name
- NCT07403682
- Testing
- Modifiye throcoabdominal nerve block through the perichondrial approach (M-TAPA), erector spinae plane block (ESPB)
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 130 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Transcutaneous, Pulsed Radiofrequency
Transcutaneous Pulsed Radiofrequency Application Plus Genicular Nerve Block Versus Intraarticular Hyaluronic Acid Injection for Management of Chronic Pain in Knee Osteoarthritis.
The aim of the present study is to compare the analgesic efficacy of combined transcutaneous pulsed radiofrequency plus genicular nerve block with bupivacaine plus corticosteroid versus intraarticular Hyaluronic acid injections…
- Conditions
- Transcutaneous, Pulsed Radiofrequency, Genicular Nerve Block, Intraarticular
- Trial name
- NCT06710782
- Testing
- Hyaluronic acid, Transcutaneous pulsed radiofrequency
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Tanta University
Impacted Mandibular Third Molar Extraction, Post Operative Complications
A Comparison of Recovery After Impacted Wisdom Tooth Removal
Justification of the Study There is a high prevalence of impacted third molars, often accompanied by a range of postoperative complications.
- Trial name
- CESE-3M (NCT07304882)
- Testing
- serratiopeptidase, Escin, Conventional drugs
- Where
- Yemen
- Volunteers
- 24 people
- Sponsor
- University of Science and Technology, Yemen
Opioid Consumption, Incidence of Nausea and Vomiting
TAP Block for Open Radical Prostatectomy.
This is a prospective, double blind, randomized study is proposed in patients undergoing open radical prostatectomy: its objective is to establish whether continuous bilateral TAP blocks would provide adequate perioperative…
- Conditions
- Opioid Consumption, Incidence of Nausea and Vomiting, Postoperative Pain, Assessment of Recovery
- Trial name
- NCT01157546
- Testing
- Normal saline via TAP catheters, Lidocaine via TAP catheters
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
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